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Items: 1 to 50 of 111

1.

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.

Pecquet C, Chachoua I, Roy A, Balligand T, Vertenoeil G, Leroy E, Albu RI, Defour JP, Nivarthi H, Hug E, Xu E, Ould-Amer Y, Mouton C, Colau D, Vertommen D, Shwe MM, Marty C, Plo I, Vainchenker W, Kralovics R, Constantinescu SN.

Blood. 2019 Jun 20;133(25):2669-2681. doi: 10.1182/blood-2018-09-874578. Epub 2019 Mar 22.

PMID:
30902807
2.

Differential effect of inhibitory strategies of the V617 mutant of JAK2 on cytokine receptor signaling.

Leroy E, Balligand T, Pecquet C, Mouton C, Colau D, Shiau AK, Dusa A, Constantinescu SN.

J Allergy Clin Immunol. 2019 Jan 29. pii: S0091-6749(19)30115-0. doi: 10.1016/j.jaci.2018.12.1023. [Epub ahead of print]

PMID:
30707971
3.

[Omalizumab for the treatment of chronic urticaria: Real-life findings].

Hamelin A, Amsler E, Mathelier-Fusade P, Pecquet C, Bayrou O, Barbaud A, Soria A.

Ann Dermatol Venereol. 2019 Jan;146(1):9-18. doi: 10.1016/j.annder.2018.07.031. Epub 2019 Jan 9. French.

PMID:
30638684
4.

Cooccurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms.

Mambet C, Babosova O, Defour JP, Leroy E, Necula L, Stanca O, Tatic A, Berbec N, Coriu D, Belickova M, Kralova B, Lanikova L, Vesela J, Pecquet C, Saussoy P, Havelange V, Diaconu CC, Divoky V, Constantinescu SN.

Blood. 2018 Dec 20;132(25):2695-2699. doi: 10.1182/blood-2018-04-843060. Epub 2018 Oct 30. No abstract available.

PMID:
30377194
5.

Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor.

Ngo A, Koay A, Pecquet C, Diaconu CC, Jenkins DA, Shiau AK, Constantinescu SN, Choong ML.

Methods Mol Biol. 2018;1787:53-66. doi: 10.1007/978-1-4939-7847-2_4.

PMID:
29736709
6.

Eyelid allergic contact dermatitis after intravitreal injections of anti-vascular endothelial growth factor: What is the culprit? A report of 3 cases.

de Risi-Pugliese T, Amsler E, Collet E, Francès C, Barbaud A, Pecquet C, Soria A.

Contact Dermatitis. 2018 Apr 30. doi: 10.1111/cod.13000. [Epub ahead of print] No abstract available.

PMID:
29708276
7.

Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response.

Barbieri D, Elvira-Matelot E, Pelinski Y, Genève L, de Laval B, Yogarajah G, Pecquet C, Constantinescu SN, Porteu F.

J Exp Med. 2018 May 7;215(5):1463-1480. doi: 10.1084/jem.20170997. Epub 2018 Apr 3.

8.

Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction.

Badaoui A, Pecquet C, Fargeas C, Mahé E.

Contact Dermatitis. 2017 Dec;77(6):423-424. doi: 10.1111/cod.12854. No abstract available.

PMID:
29164698
9.

Severe allergic contact dermatitis caused by octylisothiazolinone in a leather sofa: two new cases.

Raison-Peyron N, Amsler E, Pecquet C, Du-Thanh A, Naessens T, Apers S, Aerts O.

Contact Dermatitis. 2017 Sep;77(3):176-178. doi: 10.1111/cod.12793. No abstract available.

PMID:
28766805
10.

Airborne allergic contact dermatitis caused by isothiazolinones in water-based paints: a retrospective study of 44 cases.

Amsler E, Aerts O, Raison-Peyron N, Debons M, Milpied B, Giordano-Labadie F, Waton J, Ferrier-Le Bouëdec MC, Lartigau I, Pecquet C, Assier H, Avenel-Audran M, Bernier C, Castelain F, Collet E, Crépy MN, Genillier N, Girardin P, Pralong P, Tetart F, Vital-Durand D, Soria A, Barbaud A; Dermatology Allergy Group (DAG) of the French Society of Dermatology.

Contact Dermatitis. 2017 Sep;77(3):163-170. doi: 10.1111/cod.12795. Epub 2017 Apr 27.

PMID:
28449346
11.

The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin.

Varghese LN, Defour JP, Pecquet C, Constantinescu SN.

Front Endocrinol (Lausanne). 2017 Mar 31;8:59. doi: 10.3389/fendo.2017.00059. eCollection 2017. Review.

12.

An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L.

Favale F, Messaoudi K, Varghese LN, Boukour S, Pecquet C, Gryshkova V, Defour JP, Albu RI, Bluteau O, Ballerini P, Leverger G, Plo I, Debili N, Raslova H, Favier R, Constantinescu SN, Vainchenker W.

Blood. 2016 Dec 29;128(26):3146-3158. doi: 10.1182/blood-2016-06-722058. Epub 2016 Nov 10.

13.

A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms.

Ngo A, Koay AZ, Pecquet C, Diaconu CC, Ould-Amer Y, Huang Q, Kang C, Poulsen A, Lee MA, Jenkins D, Shiau A, Constantinescu SN, Choong ML.

Comb Chem High Throughput Screen. 2016;19(10):824-833. doi: 10.2174/1386207319666161010163825.

PMID:
27748177
14.

Cooperation of germ line JAK2 mutations E846D and R1063H in hereditary erythrocytosis with megakaryocytic atypia.

Kapralova K, Horvathova M, Pecquet C, Fialova Kucerova J, Pospisilova D, Leroy E, Kralova B, Milosevic Feenstra JD, Schischlik F, Kralovics R, Constantinescu SN, Divoky V.

Blood. 2016 Sep 8;128(10):1418-23. doi: 10.1182/blood-2016-02-698951. Epub 2016 Jul 7.

15.

Non-ischemic cerebral enhancing lesions secondary to endovascular aneurysm therapy: nickel allergy or foreign body reaction? Case series and review of the literature.

Shotar E, Law-Ye B, Baronnet-Chauvet F, Zeidan S, Psimaras D, Bielle F, Pecquet C, Navarro S, Rosso C, Cohen F, Chiras J, Di Maria F, Sourour N, Clarençon F.

Neuroradiology. 2016 Sep;58(9):877-85. doi: 10.1007/s00234-016-1699-5. Epub 2016 May 23. Review.

PMID:
27216205
16.

Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin.

Balligand T, Achouri Y, Pecquet C, Chachoua I, Nivarthi H, Marty C, Vainchenker W, Plo I, Kralovics R, Constantinescu SN.

Leukemia. 2016 Aug;30(8):1775-8. doi: 10.1038/leu.2016.47. Epub 2016 Feb 29. No abstract available.

PMID:
26987905
17.

Thrombopoietin receptor is required for the oncogenic function of CALR mutants.

Nivarthi H, Chen D, Cleary C, Kubesova B, Jäger R, Bogner E, Marty C, Pecquet C, Vainchenker W, Constantinescu SN, Kralovics R.

Leukemia. 2016 Aug;30(8):1759-63. doi: 10.1038/leu.2016.32. Epub 2016 Feb 17. No abstract available.

18.

Allergic contact dermatitis caused by methylisothiazolinone in hair gel.

Badaoui A, Bayrou O, Fite C, Frances C, Soria A, Pecquet C.

Contact Dermatitis. 2015 Dec;73(6):364-6. doi: 10.1111/cod.12467. No abstract available.

PMID:
26768996
19.

Immediate hypersensitivity to iodinated contrast media: diagnostic accuracy of skin tests and intravenous provocation test with low dose.

Sesé L, Gaouar H, Autegarden JE, Alari A, Amsler E, Vial-Dupuy A, Pecquet C, Francès C, Soria A.

Clin Exp Allergy. 2016 Mar;46(3):472-8. doi: 10.1111/cea.12703.

PMID:
26750091
20.

Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.

Chachoua I, Pecquet C, El-Khoury M, Nivarthi H, Albu RI, Marty C, Gryshkova V, Defour JP, Vertenoeil G, Ngo A, Koay A, Raslova H, Courtoy PJ, Choong ML, Plo I, Vainchenker W, Kralovics R, Constantinescu SN.

Blood. 2016 Mar 10;127(10):1325-35. doi: 10.1182/blood-2015-11-681932. Epub 2015 Dec 14.

21.

Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis.

Marty C, Pecquet C, Nivarthi H, El-Khoury M, Chachoua I, Tulliez M, Villeval JL, Raslova H, Kralovics R, Constantinescu SN, Plo I, Vainchenker W.

Blood. 2016 Mar 10;127(10):1317-24. doi: 10.1182/blood-2015-11-679571. Epub 2015 Nov 25.

22.

PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib.

Arts FA, Chand D, Pecquet C, Velghe AI, Constantinescu S, Hallberg B, Demoulin JB.

Oncogene. 2016 Jun 23;35(25):3239-48. doi: 10.1038/onc.2015.383. Epub 2015 Oct 12.

PMID:
26455322
23.

Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms.

Defour JP, Chachoua I, Pecquet C, Constantinescu SN.

Leukemia. 2016 May;30(5):1214-6. doi: 10.1038/leu.2015.271. Epub 2015 Oct 6. No abstract available.

PMID:
26437785
24.

[Bullous rash around a peritoneal dialysis catheter exit site].

Chasset F, Pecquet C, Cury K, Sesé L, Moguelet P, Francès C, Gharbi C, Senet P.

Ann Dermatol Venereol. 2015 Jun-Jul;142(6-7):438-42. doi: 10.1016/j.annder.2015.04.016. Epub 2015 May 18. French.

PMID:
25999261
25.

An outbreak of contact allergy to cocamide diethanolamide?

Badaoui A, Amsler E, Raison-Peyron N, Vigan M, Pecquet C, Frances C, Soria A.

Contact Dermatitis. 2015 Jun;72(6):407-9. doi: 10.1111/cod.12332. Epub 2015 Feb 24. No abstract available.

PMID:
25712779
26.

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.

Girardot M, Pecquet C, Chachoua I, Van Hees J, Guibert S, Ferrant A, Knoops L, Baxter EJ, Beer PA, Giraudier S, Moriggl R, Vainchenker W, Green AR, Constantinescu SN.

Oncogene. 2015 Mar 5;34(10):1323-32. doi: 10.1038/onc.2014.60. Epub 2014 Mar 31.

27.

[A study of 19 cases of allergy to heparins with positive skin testing].

Phan C, Vial-Dupuy A, Autegarden JE, Amsler E, Gaouar H, Abuaf N, Pecquet C, Francès C, Soria A.

Ann Dermatol Venereol. 2014 Jan;141(1):23-9. doi: 10.1016/j.annder.2013.10.040. Epub 2013 Dec 2. French.

PMID:
24461090
28.

Allergic reactions to insect secretions.

Pecquet C.

Eur J Dermatol. 2013 Nov-Dec;23(6):767-73. doi: 10.1684/ejd.2013.2186. Review.

PMID:
24449611
29.

Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors.

Marty C, Saint-Martin C, Pecquet C, Grosjean S, Saliba J, Mouton C, Leroy E, Harutyunyan AS, Abgrall JF, Favier R, Toussaint A, Solary E, Kralovics R, Constantinescu SN, Najman A, Vainchenker W, Plo I, Bellanné-Chantelot C.

Blood. 2014 Feb 27;123(9):1372-83. doi: 10.1182/blood-2013-05-504555. Epub 2014 Jan 7.

30.

Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors.

Choong ML, Pecquet C, Pendharkar V, Diaconu CC, Yong JW, Tai SJ, Wang SF, Defour JP, Sangthongpitag K, Villeval JL, Vainchenker W, Constantinescu SN, Lee MA.

J Cell Mol Med. 2013 Nov;17(11):1397-409. doi: 10.1111/jcmm.12156. Epub 2013 Nov 19.

31.

Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.

Constantinescu SN, Leroy E, Gryshkova V, Pecquet C, Dusa A.

Biochem Soc Trans. 2013 Aug;41(4):1048-54. doi: 10.1042/BST20130084. Review.

PMID:
23863177
32.

Cutaneous adverse drug reaction to oral acetazolamide and skin tests.

Jachiet M, Bellon N, Assier H, Amsler E, Gaouar H, Pecquet C, Bourrain JL, Bégon E, Chosidow O, Francès C, Ingen-Housz-Oro S, Soria A.

Dermatology. 2013;226(4):347-52. doi: 10.1159/000350939. Epub 2013 Jun 29.

PMID:
23817276
33.

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.

Mead AJ, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, Lutteropp M, Woll P, Chowdhury O, Luc S, Buza-Vidas N, Ferry H, Clark SA, Goardon N, Vyas P, Constantinescu SN, Sitnicka E, Nerlov C, Jacobsen SE.

Cell Rep. 2013 Jun 27;3(6):1766-76. doi: 10.1016/j.celrep.2013.04.031. Epub 2013 May 30.

34.

Chronic contact eczema on the hand related to PlayStation(®) controller use.

Kluger N, Pecquet C.

Int J Dermatol. 2014 Mar;53(3):e196-7. doi: 10.1111/ijd.12018. Epub 2013 May 15. No abstract available.

PMID:
23676210
35.

Impact of isolated germline JAK2V617I mutation on human hematopoiesis.

Mead AJ, Chowdhury O, Pecquet C, Dusa A, Woll P, Atkinson D, Burns A, Score J, Rugless M, Clifford R, Moule S, Bienz N, Vyas P, Cross N, Gale RE, Henderson S, Constantinescu SN, Schuh A, Jacobsen SE.

Blood. 2013 May 16;121(20):4156-65. doi: 10.1182/blood-2012-05-430926. Epub 2013 Mar 27.

36.

Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation.

Defour JP, Itaya M, Gryshkova V, Brett IC, Pecquet C, Sato T, Smith SO, Constantinescu SN.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2540-5. doi: 10.1073/pnas.1211560110. Epub 2013 Jan 28.

37.

Continuous subcutaneous insulin infusion allows tolerance induction and diabetes treatment in a type 1 diabetic child with insulin allergy.

Hasselmann C, Pecquet C, Bismuth E, Raverdy C, Sola-Gazagnes A, Lobut JB, Carel JC, Tubiana-Rufi N.

Diabetes Metab. 2013 Apr;39(2):174-7. doi: 10.1016/j.diabet.2012.10.002. Epub 2012 Dec 1.

PMID:
23206896
38.

Barley γ3-hordein: glycosylation at an atypical site, disulfide bridge analysis, and reactivity with IgE from patients allergic to wheat.

Snégaroff J, Bouchez I, Smaali Mel A, Pecquet C, Raison-Peyron N, Jolivet P, Laurière M.

Biochim Biophys Acta. 2013 Jan;1834(1):395-403. doi: 10.1016/j.bbapap.2012.07.016. Epub 2012 Aug 4.

PMID:
22885023
39.

A recombinant ω-gliadin-like D-type glutenin and an α-gliadin from wheat (Triticum aestivum): two immunoglobulin E binding proteins, useful for the diagnosis of wheat-dependent allergies.

Mameri H, Bouchez I, Pecquet C, Raison-Peyron N, Choudat D, Chabane H, Kerre S, Denery-Papini S, Gohon Y, Briozzo P, Laurière M, Snégaroff J.

J Agric Food Chem. 2012 Aug 15;60(32):8059-68. doi: 10.1021/jf301992w. Epub 2012 Aug 3.

PMID:
22809016
40.

Immunoglobulin-E reactivity and structural analysis of wheat low-molecular-weight glutenin subunits and their repetitive and nonrepetitive halves.

Mameri H, Snégaroff J, Gohon Y, Pecquet C, Choudat D, Raison-Peyron N, Denery-Papini S, Wien F, Briozzo P.

J Agric Food Chem. 2012 Aug 1;60(30):7538-47. doi: 10.1021/jf3007568. Epub 2012 Jul 17.

PMID:
22747247
41.

Five cases of contact dermatitis to a trendy pet.

Amsler E, Bayrou O, Pecquet C, Francès C.

Dermatology. 2012;224(4):292-4. doi: 10.1159/000338890. Epub 2012 Jun 1.

PMID:
22677934
42.

[Dermatoses associated with high technology (cell phones, computers and video games)].

Kluger N, Pecquet C.

Ann Dermatol Venereol. 2012 Mar;139(3):230-8; quiz 229, 239. doi: 10.1016/j.annder.2011.09.192. Epub 2012 Jan 31. French. No abstract available.

PMID:
22401694
43.

Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes.

Pecquet C, Diaconu CC, Staerk J, Girardot M, Marty C, Royer Y, Defour JP, Dusa A, Besancenot R, Giraudier S, Villeval JL, Knoops L, Courtoy PJ, Vainchenker W, Constantinescu SN.

Blood. 2012 May 17;119(20):4625-35. doi: 10.1182/blood-2011-08-372524. Epub 2012 Feb 29.

44.

New pets and allergies.

Pecquet C.

Eur J Dermatol. 2012 Jan-Feb;22(1):14-22. doi: 10.1684/ejd.2011.1555. Review.

PMID:
22062496
45.

Orientation-specific signalling by thrombopoietin receptor dimers.

Staerk J, Defour JP, Pecquet C, Leroy E, Antoine-Poirel H, Brett I, Itaya M, Smith SO, Vainchenker W, Constantinescu SN.

EMBO J. 2011 Sep 2;30(21):4398-413. doi: 10.1038/emboj.2011.315.

46.

Adverse cutaneous drug reactions to ibandronate.

Weber I, Olaiwan A, Bonte I, Artigou C, Pras-Landre V, Moguelet P, Frances C, Pecquet C.

Eur J Dermatol. 2011 Jul-Aug;21(4):591-4. doi: 10.1684/ejd.2011.1386.

PMID:
21700532
47.

Treatment with propranolol of 6 patients with idiopathic aquagenic pruritus.

Nosbaum A, Pecquet C, Bayrou O, Amsler E, Nicolas JF, Bérard F, Francès C.

J Allergy Clin Immunol. 2011 Nov;128(5):1113. doi: 10.1016/j.jaci.2011.05.001. Epub 2011 May 25. No abstract available.

PMID:
21616525
48.

JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitors.

Dusa A, Mouton C, Pecquet C, Herman M, Constantinescu SN.

PLoS One. 2010 Jun 16;5(6):e11157. doi: 10.1371/journal.pone.0011157.

49.

miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets.

Girardot M, Pecquet C, Boukour S, Knoops L, Ferrant A, Vainchenker W, Giraudier S, Constantinescu SN.

Blood. 2010 Jul 22;116(3):437-45. doi: 10.1182/blood-2008-06-165985. Epub 2010 May 5.

50.

[Contact urticaria induced by hydrolyzed wheat proteins in cosmetics].

Olaiwan A, Pecquet C, Mathelier-Fusade P, Francès C.

Ann Dermatol Venereol. 2010 Apr;137(4):281-4. doi: 10.1016/j.annder.2010.01.010. Epub 2010 Feb 18. French.

PMID:
20417361

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