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Items: 1 to 50 of 62

1.

Identification and clinical validation of a multigene assay that interrogates the biology of cancer stem cells and predicts metastasis in breast cancer: A retrospective consecutive study.

Pece S, Disalvatore D, Tosoni D, Vecchi M, Confalonieri S, Bertalot G, Viale G, Colleoni M, Veronesi P, Galimberti V, Di Fiore PP.

EBioMedicine. 2019 Apr;42:352-362. doi: 10.1016/j.ebiom.2019.02.036. Epub 2019 Mar 5.

2.

Prep1 (pKnox1) transcription factor contributes to pubertal mammary gland branching morphogenesis.

Sicouri L, Pisati F, Pece S, Blasi F, Longobardi E.

Int J Dev Biol. 2018;62(11-12):827-836. doi: 10.1387/ijdb.180278fb.

3.

A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility.

Zobel M, Disanza A, Senic-Matuglia F, Franco M, Colaluca IN, Confalonieri S, Bisi S, Barbieri E, Caldieri G, Sigismund S, Pece S, Chavrier P, Di Fiore PP, Scita G.

J Cell Biol. 2018 Sep 3;217(9):3161-3182. doi: 10.1083/jcb.201802023. Epub 2018 Jul 30.

4.

Author Correction: A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.

Nat Commun. 2018 May 22;9(1):2085. doi: 10.1038/s41467-018-04515-y.

5.

High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis.

Avanzato D, Pupo E, Ducano N, Isella C, Bertalot G, Luise C, Pece S, Bruna A, Rueda OM, Caldas C, Di Fiore PP, Sapino A, Lanzetti L.

Cancer Res. 2018 Jul 1;78(13):3432-3444. doi: 10.1158/0008-5472.CAN-17-3018. Epub 2018 Apr 24.

6.

A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.

Nat Commun. 2018 Apr 16;9(1):1475. doi: 10.1038/s41467-018-03571-8. Erratum in: Nat Commun. 2018 May 22;9(1):2085.

7.

Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, di Cantogno LV, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2018 Mar 30;9:16203. doi: 10.1038/ncomms16203.

8.

A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.

Colaluca IN, Basile A, Freiburger L, D'Uva V, Disalvatore D, Vecchi M, Confalonieri S, Tosoni D, Cecatiello V, Malabarba MG, Yang CJ, Kainosho M, Sattler M, Mapelli M, Pece S, Di Fiore PP.

J Cell Biol. 2018 Feb 5;217(2):745-762. doi: 10.1083/jcb.201709092. Epub 2017 Dec 21.

9.

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.

Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E.

Cancer Cell. 2017 Oct 9;32(4):444-459.e7. doi: 10.1016/j.ccell.2017.09.002.

10.

The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.

Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, Verdun di Cantogno L, Dallaglio K, Castellano I, Amici A, Centonze G, Sharma N, Lunardi S, Cabodi S, Cavallo F, Lamolinara A, Stramucci L, Moiso E, Provero P, Albini A, Sapino A, Staaf J, Di Fiore PP, Bertalot G, Pece S, Tosoni D, Confalonieri S, Iezzi M, Di Stefano P, Turco E, Defilippi P.

Nat Commun. 2017 Mar 16;8:14797. doi: 10.1038/ncomms14797. Erratum in: Nat Commun. 2018 Mar 30;9:16203.

11.

Pre-clinical validation of a selective anti-cancer stem cell therapy for Numb-deficient human breast cancers.

Tosoni D, Pambianco S, Ekalle Soppo B, Zecchini S, Bertalot G, Pruneri G, Viale G, Di Fiore PP, Pece S.

EMBO Mol Med. 2017 May;9(5):655-671. doi: 10.15252/emmm.201606940.

12.

Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.

Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, Confalonieri S, Bertalot G, Pece S, Settembre C, Malouf GG, Leemans JC, de Heer E, Salvatore M, Peters DJ, Di Fiore PP, Ballabio A.

Elife. 2016 Sep 26;5. pii: e17047. doi: 10.7554/eLife.17047.

13.

Sensitive and affordable diagnostic assay for the quantitative detection of anaplastic lymphoma kinase (ALK) alterations in patients with non-small cell lung cancer.

Dama E, Tillhon M, Bertalot G, de Santis F, Troglio F, Pessina S, Passaro A, Pece S, de Marinis F, Dell'Orto P, Viale G, Spaggiari L, Di Fiore PP, Bianchi F, Barberis M, Vecchi M.

Oncotarget. 2016 Jun 14;7(24):37160-37176. doi: 10.18632/oncotarget.9471.

14.

The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.

Tosoni D, Zecchini S, Coazzoli M, Colaluca I, Mazzarol G, Rubio A, Caccia M, Villa E, Zilian O, Di Fiore PP, Pece S.

J Cell Biol. 2015 Nov 23;211(4):845-62. doi: 10.1083/jcb.201505037.

15.

A Trust-Based Pact in Research Biobanks. From Theory to Practice.

Sanchini V, Bonizzi G, Disalvatore D, Monturano M, Pece S, Viale G, Di Fiore PP, Boniolo G.

Bioethics. 2016 May;30(4):260-71. doi: 10.1111/bioe.12184. Epub 2015 Aug 26.

PMID:
26307361
16.

Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer.

Chiaradonna F, Barozzi I, Miccolo C, Bucci G, Palorini R, Fornasari L, Botrugno OA, Pruneri G, Masullo M, Passafaro A, Galimberti VE, Fantin VR, Richon VM, Pece S, Viale G, Di Fiore PP, Draetta G, Pelicci PG, Minucci S, Chiocca S.

Antioxid Redox Signal. 2015 Jul 1;23(1):15-29. doi: 10.1089/ars.2014.6189. Epub 2015 May 27.

17.

Whole exome sequencing identifies driver mutations in asymptomatic computed tomography-detected lung cancers with normal karyotype.

Belloni E, Veronesi G, Rotta L, Volorio S, Sardella D, Bernard L, Pece S, Di Fiore PP, Fumagalli C, Barberis M, Spaggiari L, Pelicci PG, Riva L.

Cancer Genet. 2015 Apr;208(4):152-5. doi: 10.1016/j.cancergen.2015.02.004. Epub 2015 Feb 20.

PMID:
25850996
18.

HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.

Puca F, Colamaio M, Federico A, Gemei M, Tosti N, Bastos AU, Del Vecchio L, Pece S, Battista S, Fusco A.

Oncotarget. 2014 May 30;5(10):3234-45.

19.

flowFit: a Bioconductor package to estimate proliferation in cell-tracking dye studies.

Rambaldi D, Pece S, Di Fiore PP.

Bioinformatics. 2014 Jul 15;30(14):2060-5. doi: 10.1093/bioinformatics/btu127. Epub 2014 Mar 27.

PMID:
24681909
20.

TPT1/ TCTP-regulated pathways in phenotypic reprogramming.

Amson R, Pece S, Marine JC, Di Fiore PP, Telerman A.

Trends Cell Biol. 2013 Jan;23(1):37-46. doi: 10.1016/j.tcb.2012.10.002. Epub 2012 Oct 30. Review.

21.

Functional purification of human and mouse mammary stem cells.

Tosoni D, Di Fiore PP, Pece S.

Methods Mol Biol. 2012;916:59-79. doi: 10.1007/978-1-61779-980-8_6.

PMID:
22914933
22.

Reciprocal repression between P53 and TCTP.

Amson R, Pece S, Lespagnol A, Vyas R, Mazzarol G, Tosoni D, Colaluca I, Viale G, Rodrigues-Ferreira S, Wynendaele J, Chaloin O, Hoebeke J, Marine JC, Di Fiore PP, Telerman A.

Nat Med. 2011 Dec 11;18(1):91-9. doi: 10.1038/nm.2546.

PMID:
22157679
23.

Cobalamin deficiency-induced changes of epidermal growth factor (EGF)-receptor expression and EGF levels in rat spinal cord.

Mutti E, Magnaghi V, Veber D, Faroni A, Pece S, Di Fiore PP, Scalabrino G.

Brain Res. 2011 Feb 28;1376:23-30. doi: 10.1016/j.brainres.2010.12.056. Epub 2010 Dec 23.

PMID:
21185268
24.

Genomic characterization of asymptomatic CT-detected lung cancers.

Belloni E, Veronesi G, Micucci C, Javan S, Minardi SP, Venturini E, Maisonneuve P, Volorio S, Riboni M, Bellomi M, Scanagatta P, Taliento G, Pelosi G, Pece S, Spaggiari L, Pelicci PG.

Oncogene. 2011 Mar 3;30(9):1117-26. doi: 10.1038/onc.2010.478. Epub 2010 Oct 25.

PMID:
20972464
25.

NUMB-ing down cancer by more than just a NOTCH.

Pece S, Confalonieri S, R Romano P, Di Fiore PP.

Biochim Biophys Acta. 2011 Jan;1815(1):26-43. doi: 10.1016/j.bbcan.2010.10.001. Epub 2010 Oct 16. Review.

PMID:
20940030
26.

Trusted consent and research biobanks: towards a 'new alliance' between researchers and donors.

Boniolo G, Di Fiore PP, Pece S.

Bioethics. 2012 Feb;26(2):93-100. doi: 10.1111/j.1467-8519.2010.01823.x. Epub 2010 May 17.

PMID:
20497169
27.

Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.

Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S, Bernard L, Viale G, Pelicci PG, Di Fiore PP.

Cell. 2010 Jan 8;140(1):62-73. doi: 10.1016/j.cell.2009.12.007.

28.

Alterations of the Notch pathway in lung cancer.

Westhoff B, Colaluca IN, D'Ario G, Donzelli M, Tosoni D, Volorio S, Pelosi G, Spaggiari L, Mazzarol G, Viale G, Pece S, Di Fiore PP.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22293-8. doi: 10.1073/pnas.0907781106. Epub 2009 Dec 10.

29.

Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor.

Confalonieri S, Quarto M, Goisis G, Nuciforo P, Donzelli M, Jodice G, Pelosi G, Viale G, Pece S, Di Fiore PP.

Oncogene. 2009 Aug 20;28(33):2959-68. doi: 10.1038/onc.2009.156. Epub 2009 Jun 22.

PMID:
19543318
30.

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer.

Rustighi A, Tiberi L, Soldano A, Napoli M, Nuciforo P, Rosato A, Kaplan F, Capobianco A, Pece S, Di Fiore PP, Del Sal G.

Nat Cell Biol. 2009 Feb;11(2):133-42. doi: 10.1038/ncb1822. Epub 2009 Jan 18.

PMID:
19151708
31.

Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas.

Maiorano E, Favia G, Pece S, Resta L, Maisonneuve P, Di Fiore PP, Capodiferro S, Urbani U, Viale G.

Int J Immunopathol Pharmacol. 2007 Oct-Dec;20(4):779-89.

PMID:
18179751
32.

NUMB controls p53 tumour suppressor activity.

Colaluca IN, Tosoni D, Nuciforo P, Senic-Matuglia F, Galimberti V, Viale G, Pece S, Di Fiore PP.

Nature. 2008 Jan 3;451(7174):76-80. doi: 10.1038/nature06412.

PMID:
18172499
33.

Breast cancer metastases are molecularly distinct from their primary tumors.

Vecchi M, Confalonieri S, Nuciforo P, Viganò MA, Capra M, Bianchi M, Nicosia D, Bianchi F, Galimberti V, Viale G, Palermo G, Riccardi A, Campanini R, Daidone MG, Pierotti MA, Pece S, Di Fiore PP.

Oncogene. 2008 Apr 3;27(15):2148-58. Epub 2007 Oct 22.

PMID:
17952122
34.

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.

Mey V, Giovannetti E, De Braud F, Nannizzi S, Curigliano G, Verweij F, De Cobelli O, Pece S, Del Tacca M, Danesi R.

Br J Cancer. 2006 Aug 7;95(3):289-97. Epub 2006 Jul 25.

35.

Cyclin D3 immunoreactivity is an independent predictor of survival in laryngeal squamous cell carcinoma.

Pruneri G, Pignataro L, Valentini S, Fabris S, Maisonneuve P, Carboni N, Pece S, Capra M, Del Curto B, Neri A, Viale G.

Clin Cancer Res. 2005 Jan 1;11(1):242-8.

36.

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis.

Pece S, Serresi M, Santolini E, Capra M, Hulleman E, Galimberti V, Zurrida S, Maisonneuve P, Viale G, Di Fiore PP.

J Cell Biol. 2004 Oct 25;167(2):215-21. Epub 2004 Oct 18.

37.

Endocytosis and cancer.

Polo S, Pece S, Di Fiore PP.

Curr Opin Cell Biol. 2004 Apr;16(2):156-61. Review.

PMID:
15196558
38.

E-cadherin and Hakai: signalling, remodeling or destruction?

Pece S, Gutkind JS.

Nat Cell Biol. 2002 Apr;4(4):E72-4. No abstract available.

PMID:
11944035
39.
40.

Loss of PTEN expression leading to high Akt activation in human multiple myelomas.

Hyun T, Yam A, Pece S, Xie X, Zhang J, Miki T, Gutkind JS, Li W.

Blood. 2000 Nov 15;96(10):3560-8.

42.

Helicobacter pylori infection and host cell responses.

Di Leo A, Messa C, Russo F, Linsalata M, Amati L, Caradonna L, Pece S, Pellegrino NM, Caccavo D, Antonaci S, Jirillo E.

Immunopharmacol Immunotoxicol. 1999 Nov;21(4):803-46. Review.

PMID:
10584213
43.

Lactoferrin-lipid A-lipopolysaccharide interaction: inhibition by anti-human lactoferrin monoclonal antibody AGM 10.14.

Caccavo D, Afeltra A, Pece S, Giuliani G, Freudenberg M, Galanos C, Jirillo E.

Infect Immun. 1999 Sep;67(9):4668-72.

45.

Spontaneous and Fas-induced apoptotic cell death in aged neutrophils.

Tortorella C, Piazzolla G, Spaccavento F, Pece S, Jirillo E, Antonaci S.

J Clin Immunol. 1998 Sep;18(5):321-9.

PMID:
9793824
46.

In vitro production of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 from normal human peripheral blood mononuclear cells stimulated by Rhodococcus equi.

Pece S, Giuliani G, Fumarola D, Mastroianni CM, Lichtner M, Vullo V, Antonaci S, Jirillo E.

Vet Microbiol. 1997 Jun 16;56(3-4):277-85.

PMID:
9226842
47.

Role of lipopolysaccharide and related cytokines in Helicobacter pylori infection.

Pece S, Giuliani G, Di Leo A, Fumarola D, Antonaci S, Jirillo E.

Recenti Prog Med. 1997 May;88(5):237-41. Review.

PMID:
9200967
48.

Pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. A review.

Covelli V, Pece S, Giuliani G, De Simone C, Jirillo E.

Immunopharmacol Immunotoxicol. 1997 May;19(2):147-64. Review.

PMID:
9130002
49.

Effect of Helicobacter pylori lipopolysaccharide (LPS) and LPS derivatives on the production of tissue factor and plasminogen activator inhibitor type 2 by human blood mononuclear cells.

Semeraro N, Montemurro P, Piccoli C, Muolo V, Colucci M, Giuliani G, Fumarola D, Pece S, Moran AP.

J Infect Dis. 1996 Dec;174(6):1255-60.

PMID:
8940216
50.

Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats.

Mitolo-Chieppa D, Serio M, Potenza MA, Montagnani M, Mansi G, Pece S, Jirillo E, Stoclet JC.

Eur J Pharmacol. 1996 Aug 8;309(2):175-82.

PMID:
8874136

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