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Items: 29

1.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

2.

Dictyostelium as a Model to Assess Site-Specific ADP-Ribosylation Events.

Kolb AL, Hsu DW, Wallis ABA, Ura S, Rakhimova A, Pears CJ, Lakin ND.

Methods Mol Biol. 2018;1813:125-148. doi: 10.1007/978-1-4939-8588-3_9.

PMID:
30097865
3.

Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks.

Rakhimova A, Ura S, Hsu DW, Wang HY, Pears CJ, Lakin ND.

Sci Rep. 2017 Mar 2;7:43750. doi: 10.1038/srep43750.

4.

Emerging models for DNA repair: Dictyostelium discoideum as a model for nonhomologous end-joining.

Pears CJ, Lakin ND.

DNA Repair (Amst). 2014 May;17:121-31. doi: 10.1016/j.dnarep.2014.01.008. Epub 2014 Feb 16.

PMID:
24548787
5.

Nonhomologous end-joining promotes resistance to DNA damage in the absence of an ADP-ribosyltransferase that signals DNA single strand breaks.

Couto CA, Hsu DW, Teo R, Rakhimova A, Lempidaki S, Pears CJ, Lakin ND.

J Cell Sci. 2013 Aug 1;126(Pt 15):3452-61. doi: 10.1242/jcs.128769. Epub 2013 Jun 7.

6.

Investigation of DNA repair pathway activity.

Couto AM, Lakin ND, Pears CJ.

Methods Mol Biol. 2013;983:295-310. doi: 10.1007/978-1-62703-302-2_16.

PMID:
23494314
7.

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

Unsworth AJ, Finney BA, Navarro-Nunez L, Severin S, Watson SP, Pears CJ.

J Thromb Haemost. 2012 Sep;10(9):1887-94. doi: 10.1111/j.1538-7836.2012.04857.x. Erratum in: J Thromb Haemost. 2013 Jan;11(1):217.

8.

Dynamic acetylation of lysine-4-trimethylated histone H3 and H3 variant biology in a simple multicellular eukaryote.

Hsu DW, Chubb JR, Muramoto T, Pears CJ, Mahadevan LC.

Nucleic Acids Res. 2012 Aug;40(15):7247-56. doi: 10.1093/nar/gks367. Epub 2012 May 16.

9.

The role of ADP-ribosylation in regulating DNA double-strand break repair.

Pears CJ, Couto CA, Wang HY, Borer C, Kiely R, Lakin ND.

Cell Cycle. 2012 Jan 1;11(1):48-56. doi: 10.4161/cc.11.1.18793. Epub 2012 Jan 1. Review.

10.

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks.

Couto CA, Wang HY, Green JC, Kiely R, Siddaway R, Borer C, Pears CJ, Lakin ND.

J Cell Biol. 2011 Aug 8;194(3):367-75. doi: 10.1083/jcb.201012132. Epub 2011 Aug 1.

11.

DNA double-strand break repair pathway choice in Dictyostelium.

Hsu DW, Kiely R, Couto CA, Wang HY, Hudson JJ, Borer C, Pears CJ, Lakin ND.

J Cell Sci. 2011 May 15;124(Pt 10):1655-63. doi: 10.1242/jcs.081471.

12.

Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.

Unsworth AJ, Smith H, Gissen P, Watson SP, Pears CJ.

J Biol Chem. 2011 Jun 17;286(24):21073-82. doi: 10.1074/jbc.M110.187138. Epub 2011 Apr 13.

13.

Targets downstream of Cdk8 in Dictyostelium development.

Greene DM, Bloomfield G, Skelton J, Ivens A, Pears CJ.

BMC Dev Biol. 2011 Jan 21;11:2. doi: 10.1186/1471-213X-11-2.

14.

Control of cyclin C levels during development of Dictyostelium.

Greene DM, Hsu DW, Pears CJ.

PLoS One. 2010 May 7;5(5):e10543. doi: 10.1371/journal.pone.0010543.

15.

Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

Pears CJ, Thornber K, Auger JM, Hughes CE, Grygielska B, Protty MB, Pearce AC, Watson SP.

PLoS One. 2008;3(11):e3793. doi: 10.1371/journal.pone.0003793. Epub 2008 Nov 24.

16.
17.

DNA damage signaling and repair in Dictyostelium discoideum.

Hsu DW, Gaudet P, Hudson JJ, Pears CJ, Lakin ND.

Cell Cycle. 2006 Apr;5(7):702-8. Epub 2006 Apr 1. Review.

PMID:
16582628
18.

DNA-PKcs-dependent signaling of DNA damage in Dictyostelium discoideum.

Hudson JJ, Hsu DW, Guo K, Zhukovskaya N, Liu PH, Williams JG, Pears CJ, Lakin ND.

Curr Biol. 2005 Oct 25;15(20):1880-5.

19.

Developmental decisions in Dictyostelium discoideum.

Strmecki L, Greene DM, Pears CJ.

Dev Biol. 2005 Aug 1;284(1):25-36. Review.

20.

PKD: a new protein kinase C-dependent pathway in platelets.

Stafford MJ, Watson SP, Pears CJ.

Blood. 2003 Feb 15;101(4):1392-9. Epub 2002 Oct 10.

PMID:
12393506
21.

Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.

Stafford MJ, Atkinson BT, Watson SP, Pears CJ.

Platelets. 2001 Dec;12(8):476-85.

PMID:
11798397
22.

Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.

Atkinson BT, Stafford MJ, Pears CJ, Watson SP.

Eur J Biochem. 2001 Oct;268(20):5242-8.

24.

Domain interactions in protein kinase C.

Pears CJ, Parker PJ.

J Cell Sci. 1991 Dec;100 ( Pt 4):683-6. Review. No abstract available.

25.

Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation.

Pears CJ, Kour G, House C, Kemp BE, Parker PJ.

Eur J Biochem. 1990 Nov 26;194(1):89-94.

29.

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