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Items: 1 to 50 of 59

1.

A regional Australasian experience of extended endoscopic transsphenoidal surgery for craniopharyngioma: Progression of the mentoring model.

Gauden AJ, Harley B, Pears C, Wickremesekera A, Parker A, Robinson S, Baguley C, Wormald PJ.

J Clin Neurosci. 2019 Jul 11. pii: S0967-5868(18)31497-8. doi: 10.1016/j.jocn.2019.06.032. [Epub ahead of print]

PMID:
31303398
2.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

3.

Dictyostelium as a Model to Assess Site-Specific ADP-Ribosylation Events.

Kolb AL, Hsu DW, Wallis ABA, Ura S, Rakhimova A, Pears CJ, Lakin ND.

Methods Mol Biol. 2018;1813:125-148. doi: 10.1007/978-1-4939-8588-3_9.

PMID:
30097865
4.

Endoscopic neuroendoscopy using a novel ventricular access port.

Gauden AJ, Pears C, Parker A, Woon K, Köck H, Hunn M, Symons W, Wickremesekera A.

Br J Neurosurg. 2018 Dec;32(6):653-656. doi: 10.1080/02688697.2017.1418292. Epub 2017 Dec 20.

PMID:
29260909
5.

An enhanced C. elegans based platform for toxicity assessment.

Xiong H, Pears C, Woollard A.

Sci Rep. 2017 Aug 29;7(1):9839. doi: 10.1038/s41598-017-10454-3.

6.

Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks.

Rakhimova A, Ura S, Hsu DW, Wang HY, Pears CJ, Lakin ND.

Sci Rep. 2017 Mar 2;7:43750. doi: 10.1038/srep43750.

7.

Expanding the yeast protein arginine methylome.

Plank M, Fischer R, Geoghegan V, Charles PD, Konietzny R, Acuto O, Pears C, Schofield CJ, Kessler BM.

Proteomics. 2015 Sep;15(18):3232-43. doi: 10.1002/pmic.201500032. Epub 2015 Jul 2.

PMID:
26046779
8.

Emerging models for DNA repair: Dictyostelium discoideum as a model for nonhomologous end-joining.

Pears CJ, Lakin ND.

DNA Repair (Amst). 2014 May;17:121-31. doi: 10.1016/j.dnarep.2014.01.008. Epub 2014 Feb 16.

PMID:
24548787
9.

Nonhomologous end-joining promotes resistance to DNA damage in the absence of an ADP-ribosyltransferase that signals DNA single strand breaks.

Couto CA, Hsu DW, Teo R, Rakhimova A, Lempidaki S, Pears CJ, Lakin ND.

J Cell Sci. 2013 Aug 1;126(Pt 15):3452-61. doi: 10.1242/jcs.128769. Epub 2013 Jun 7.

10.

Investigation of DNA repair pathway activity.

Couto AM, Lakin ND, Pears CJ.

Methods Mol Biol. 2013;983:295-310. doi: 10.1007/978-1-62703-302-2_16.

PMID:
23494314
11.

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.

Unsworth AJ, Finney BA, Navarro-Nunez L, Severin S, Watson SP, Pears CJ.

J Thromb Haemost. 2012 Sep;10(9):1887-94. doi: 10.1111/j.1538-7836.2012.04857.x. Erratum in: J Thromb Haemost. 2013 Jan;11(1):217.

12.

Dynamic acetylation of lysine-4-trimethylated histone H3 and H3 variant biology in a simple multicellular eukaryote.

Hsu DW, Chubb JR, Muramoto T, Pears CJ, Mahadevan LC.

Nucleic Acids Res. 2012 Aug;40(15):7247-56. doi: 10.1093/nar/gks367. Epub 2012 May 16.

13.

The role of ADP-ribosylation in regulating DNA double-strand break repair.

Pears CJ, Couto CA, Wang HY, Borer C, Kiely R, Lakin ND.

Cell Cycle. 2012 Jan 1;11(1):48-56. doi: 10.4161/cc.11.1.18793. Epub 2012 Jan 1. Review.

14.

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks.

Couto CA, Wang HY, Green JC, Kiely R, Siddaway R, Borer C, Pears CJ, Lakin ND.

J Cell Biol. 2011 Aug 8;194(3):367-75. doi: 10.1083/jcb.201012132. Epub 2011 Aug 1.

15.

DNA double-strand break repair pathway choice in Dictyostelium.

Hsu DW, Kiely R, Couto CA, Wang HY, Hudson JJ, Borer C, Pears CJ, Lakin ND.

J Cell Sci. 2011 May 15;124(Pt 10):1655-63. doi: 10.1242/jcs.081471.

16.

Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.

Unsworth AJ, Smith H, Gissen P, Watson SP, Pears CJ.

J Biol Chem. 2011 Jun 17;286(24):21073-82. doi: 10.1074/jbc.M110.187138. Epub 2011 Apr 13.

17.

Targets downstream of Cdk8 in Dictyostelium development.

Greene DM, Bloomfield G, Skelton J, Ivens A, Pears CJ.

BMC Dev Biol. 2011 Jan 21;11:2. doi: 10.1186/1471-213X-11-2.

18.

Control of cyclin C levels during development of Dictyostelium.

Greene DM, Hsu DW, Pears CJ.

PLoS One. 2010 May 7;5(5):e10543. doi: 10.1371/journal.pone.0010543.

19.

Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

Pears CJ, Thornber K, Auger JM, Hughes CE, Grygielska B, Protty MB, Pearce AC, Watson SP.

PLoS One. 2008;3(11):e3793. doi: 10.1371/journal.pone.0003793. Epub 2008 Nov 24.

20.

Proteomic and microarray analyses of the Dictyostelium Zak1-GSK-3 signaling pathway reveal a role in early development.

Strmecki L, Bloomfield G, Araki T, Dalton E, Skelton J, Schilde C, Harwood A, Williams JG, Ivens A, Pears C.

Eukaryot Cell. 2007 Feb;6(2):245-52. Epub 2006 Nov 3.

21.
22.

DNA damage signaling and repair in Dictyostelium discoideum.

Hsu DW, Gaudet P, Hudson JJ, Pears CJ, Lakin ND.

Cell Cycle. 2006 Apr;5(7):702-8. Epub 2006 Apr 1. Review.

PMID:
16582628
23.

DNA-PKcs-dependent signaling of DNA damage in Dictyostelium discoideum.

Hudson JJ, Hsu DW, Guo K, Zhukovskaya N, Liu PH, Williams JG, Pears CJ, Lakin ND.

Curr Biol. 2005 Oct 25;15(20):1880-5.

24.

Transcriptional switch of the dia1 and impA promoter during the growth/differentiation transition.

Hirose S, Mayanagi T, Pears C, Amagai A, Loomis WF, Maeda Y.

Eukaryot Cell. 2005 Aug;4(8):1477-82.

25.

Developmental decisions in Dictyostelium discoideum.

Strmecki L, Greene DM, Pears CJ.

Dev Biol. 2005 Aug 1;284(1):25-36. Review.

26.

A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium.

Lin HH, Khosla M, Huang HJ, Hsu DW, Michaelis C, Weeks G, Pears C.

Dev Biol. 2004 Jul 1;271(1):49-58.

27.

Superoxide signalling required for multicellular development of Dictyostelium.

Bloomfield G, Pears C.

J Cell Sci. 2003 Aug 15;116(Pt 16):3387-97. Epub 2003 Jul 2.

28.

PKD: a new protein kinase C-dependent pathway in platelets.

Stafford MJ, Watson SP, Pears CJ.

Blood. 2003 Feb 15;101(4):1392-9. Epub 2002 Oct 10.

29.

Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.

Stafford MJ, Atkinson BT, Watson SP, Pears CJ.

Platelets. 2001 Dec;12(8):476-85.

PMID:
11798397
30.

A Dictyostelium nuclear phosphatidylinositol phosphate kinase required for developmental gene expression.

Guo K, Nichol R, Skehel P, Dormann D, Weijer CJ, Williams JG, Pears C.

EMBO J. 2001 Nov 1;20(21):6017-27.

31.

Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.

Atkinson BT, Stafford MJ, Pears CJ, Watson SP.

Eur J Biochem. 2001 Oct;268(20):5242-8.

32.

Cell cycle-dependent regulation of early developmental genes.

Huang H, Pears C.

Biochim Biophys Acta. 1999 Dec 9;1452(3):296-302.

33.

Protein kinase C-alpha is essential for Ramos-BL B cell survival.

Keenan C, Thompson S, Knox K, Pears C.

Cell Immunol. 1999 Sep 15;196(2):104-9.

PMID:
10527562
34.

Regulation of B cell apoptosis during the cell cycle.

Keenan C, Hall A, Pears C, Knox K.

Biochem Soc Trans. 1998 Nov;26(4):S337. No abstract available.

PMID:
10047851
35.

The role of protein kinase C in B cell apoptosis.

Keenan C, Pears C, Knox K.

Biochem Soc Trans. 1998 Nov;26(4):S336. No abstract available.

PMID:
10047850
36.

Generation of genomic mini-libraries by Taq DNA polymerase modification of genomic fragments.

Huang HJ, Pears C.

Biotechniques. 1998 Apr;24(4):566-8. No abstract available.

37.

Negative influence of RasG on chemoattractant-induced ERK2 phosphorylation in Dictyostelium.

Kosaka C, Khosla M, Weeks G, Pears C.

Biochim Biophys Acta. 1998 Mar 12;1402(1):1-5.

38.

Protein kinase C in dictyostelium discoideum.

Keenan C, Phillips P, Thio M, Pears C.

Biochem Soc Trans. 1997 Nov;25(4):S592. No abstract available.

PMID:
9450020
39.

Assay to determine the isoform specificity of protein kinase C inhibitors.

Keenan C, Goode N, Pears C.

Biochem Soc Trans. 1997 Nov;25(4):S591. No abstract available.

PMID:
9450019
40.

Cells at the center of Dictyostelium aggregates become spores.

Huang HJ, Takagawa D, Weeks G, Pears C.

Dev Biol. 1997 Dec 15;192(2):564-71.

41.

A protein kinase C-like activity involved in the chemotactic response of Dictyostelium discoideum.

Phillips P, Thio M, Pears C.

Biochim Biophys Acta. 1997 Nov 8;1349(1):72-80.

PMID:
9421198
42.

Isoform specificity of activators and inhibitors of protein kinase C gamma and delta.

Keenan C, Goode N, Pears C.

FEBS Lett. 1997 Sep 22;415(1):101-8.

44.

Protein kinase C-delta and -epsilon: a functional appraisal.

Olivier AR, Kiley SC, Pears C, Schaap D, Jaken S, Parker PJ.

Biochem Soc Trans. 1992 Aug;20(3):603-7. Review. No abstract available.

PMID:
1426597
45.

Protein kinase C.

Parker PJ, Cook PP, Olivier AR, Pears C, Ways DK, Webster C.

Biochem Soc Trans. 1992 May;20(2):415-8. Review. No abstract available.

PMID:
1397641
46.

Studies on the phosphorylation of protein kinase C-alpha.

Pears C, Stabel S, Cazaubon S, Parker PJ.

Biochem J. 1992 Apr 15;283 ( Pt 2):515-8.

47.

Domain interactions in protein kinase C.

Pears CJ, Parker PJ.

J Cell Sci. 1991 Dec;100 ( Pt 4):683-6. Review. No abstract available.

48.

Down-regulation of a kinase defective PKC-alpha.

Pears C, Parker PJ.

FEBS Lett. 1991 Jun 17;284(1):120-2.

49.

The regulatory domain of protein kinase C-epsilon restricts the catalytic-domain-specificity.

Pears C, Schaap D, Parker PJ.

Biochem J. 1991 May 15;276 ( Pt 1):257-60.

50.

Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation.

Pears CJ, Kour G, House C, Kemp BE, Parker PJ.

Eur J Biochem. 1990 Nov 26;194(1):89-94.

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