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Items: 1 to 50 of 111

1.

Aortic Arch Atherosclerosis in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Trial.

Ntaios G, Pearce LA, Meseguer E, Endres M, Amarenco P, Ozturk S, Lang W, Bornstein NM, Molina CA, Pagola J, Mundl H, Berkowitz SD, Liu YY, Sen S, Connolly SJ, Hart RG; NAVIGATE ESUS Investigators.

Stroke. 2019 Sep 17:STROKEAHA119025813. doi: 10.1161/STROKEAHA.119.025813. [Epub ahead of print]

PMID:
31526123
2.

Identifying mental health and substance use disorders using emergency department and hospital records: a population-based retrospective cohort study of diagnostic concordance and disease attribution.

Wang L, Homayra F, Pearce LA, Panagiotoglou D, McKendry R, Barrios R, Mitton C, Nosyk B.

BMJ Open. 2019 Jul 11;9(7):e030530. doi: 10.1136/bmjopen-2019-030530.

3.

An evaluation of Take Home Naloxone program implementation in British Columbian correctional facilities.

Pearce LA, Mathany L, Rothon D, Kuo M, Buxton JA.

Int J Prison Health. 2019 Mar 11;15(1):46-57. doi: 10.1108/IJPH-12-2017-0058. Epub 2019 Feb 20.

PMID:
30827160
4.

Physical, Anthropometric, and Athletic Movement Qualities Discriminate Development Level in a Rugby League Talent Pathway.

Pearce LA, Sinclair WH, Leicht AS, Woods CT.

J Strength Cond Res. 2018 Nov;32(11):3169-3176. doi: 10.1519/JSC.0000000000002350.

PMID:
30540281
5.

CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function.

Bandala-Sanchez E, G Bediaga N, Goddard-Borger ED, Ngui K, Naselli G, Stone NL, Neale AM, Pearce LA, Wardak A, Czabotar P, Haselhorst T, Maggioni A, Hartley-Tassell LA, Adams TE, Harrison LC.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7783-7788. doi: 10.1073/pnas.1722056115. Epub 2018 Jul 11. Erratum in: Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7592-7593.

6.

Predictors of Mortality in Patients With Atrial Fibrillation (from the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events [ACTIVE A]).

Perera KS, Pearce LA, Sharma M, Benavente O, Connolly SJ, Hart RG; ACTIVE A (Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events) Steering Committee and Investigators.

Am J Cardiol. 2018 Mar 1;121(5):584-589. doi: 10.1016/j.amjcard.2017.11.028. Epub 2017 Dec 11.

PMID:
29291887
7.

Microbleeds in the Secondary Prevention of Small Subcortical Strokes Trial: Stroke, mortality, and treatment interactions.

Shoamanesh A, Pearce LA, Bazan C, Catanese L, McClure LA, Sharma M, Marti-Fabregas J, Anderson DC, Kase CS, Hart RG, Benavente OR; SPS3 Trial Investigators.

Ann Neurol. 2017 Aug;82(2):196-207. doi: 10.1002/ana.24988. Epub 2017 Jul 19.

8.

Morphological classification of penetrating artery pontine infarcts and association with risk factors and prognosis: The SPS3 trial.

Wilson LK, Pearce LA, Arauz A, Anderson DC, Tapia J, Bazan C, Benavente OR, Field TS; SPS3 Investigators.

Int J Stroke. 2016 Jun;11(4):412-9. doi: 10.1177/1747493016637366. Epub 2016 Mar 8.

PMID:
26956031
9.

Structural characterization by transmission electron microscopy and immunoreactivity of recombinant Hendra virus nucleocapsid protein expressed and purified from Escherichia coli.

Pearce LA, Yu M, Waddington LJ, Barr JA, Scoble JA, Crameri GS, McKinstry WJ.

Protein Expr Purif. 2015 Dec;116:19-29. doi: 10.1016/j.pep.2015.07.008. Epub 2015 Jul 18.

PMID:
26196500
10.

Cognitive performance following lacunar stroke in Spanish-speaking patients: results from the SPS3 trial.

Jacova C, Pearce LA, Roldan AM, Arauz A, Tapia J, Costello R, McClure LA, Hart RG, Benavente OR.

Int J Stroke. 2015 Jun;10(4):519-28. doi: 10.1111/ijs.12511.

11.

Left Ventricular Geometry on Transthoracic Echocardiogram and Prognosis after Lacunar Stroke: The SPS3 Trial.

Field TS, Pearce LA, Asinger RW, Smyth NG, De SK, Hart RG, Benavente OR; SPS3 Investigators.

J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1423-9. doi: 10.1016/j.jstrokecerebrovasdis.2015.03.005. Epub 2015 Apr 1.

12.

Vertebrobasilar ectasia in patients with lacunar stroke: the secondary prevention of small subcortical strokes trial.

Nakajima M, Pearce LA, Ohara N, Field TS, Bazan C, Anderson DC, Hart RG, Benavente OR; SPS3 Investigators.

J Stroke Cerebrovasc Dis. 2015 May;24(5):1052-8. doi: 10.1016/j.jstrokecerebrovasdis.2014.12.039. Epub 2015 Mar 25.

13.

Effect of addition of clopidogrel to aspirin on subdural hematoma: meta-analysis of randomized clinical trials.

Bakheet MF, Pearce LA, Hart RG.

Int J Stroke. 2015 Jun;10(4):501-5. doi: 10.1111/ijs.12419. Epub 2014 Dec 3.

PMID:
25472690
14.

Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial.

Pearce LA, McClure LA, Anderson DC, Jacova C, Sharma M, Hart RG, Benavente OR; SPS3 Investigators.

Lancet Neurol. 2014 Dec;13(12):1177-85. doi: 10.1016/S1474-4422(14)70224-8. Epub 2014 Oct 23.

15.

Clinical correlates of infarct shape and volume in lacunar strokes: the Secondary Prevention of Small Subcortical Strokes trial.

Asdaghi N, Pearce LA, Nakajima M, Field TS, Bazan C, Cermeno F, McClure LA, Anderson DC, Hart RG, Benavente OR; SPS3 Investigators.

Stroke. 2014 Oct;45(10):2952-8. doi: 10.1161/STROKEAHA.114.005211. Epub 2014 Sep 4.

16.

Predictors of mortality in patients with lacunar stroke in the secondary prevention of small subcortical strokes trial.

Sharma M, Pearce LA, Benavente OR, Anderson DC, Connolly SJ, Palacio S, Coffey CS, Hart RG.

Stroke. 2014 Oct;45(10):2989-94. doi: 10.1161/STROKEAHA.114.005789. Epub 2014 Aug 26.

17.

Cardiac troponin changes to distinguish type 1 and type 2 myocardial infarction and 180-day mortality risk.

Sandoval Y, Thordsen SE, Smith SW, Schulz KM, Murakami MM, Pearce LA, Apple FS.

Eur Heart J Acute Cardiovasc Care. 2014 Dec;3(4):317-25. doi: 10.1177/2048872614538411. Epub 2014 Jun 25.

PMID:
24965188
18.

Vitamin K antagonists and risk of subdural hematoma: meta-analysis of randomized clinical trials.

Connolly BJ, Pearce LA, Hart RG.

Stroke. 2014 Jun;45(6):1672-8. doi: 10.1161/STROKEAHA.114.005430. Epub 2014 May 13.

PMID:
24876259
19.

Clinical-MRI correlations in a multiethnic cohort with recent lacunar stroke: the SPS3 trial.

Benavente OR, Pearce LA, Bazan C, Roldan AM, Catanese L, Bhat Livezey VM, Vidal-Pergola G, McClure LA, Hart RG; SPS3 Investigators.

Int J Stroke. 2014 Dec;9(8):1057-64. doi: 10.1111/ijs.12282. Epub 2014 May 27.

PMID:
24862645
20.

The relevance of living supports on antiplatelet adherence and trial participation: the SPS3 trial.

Lewis BL, Pearce LA, Field TS, White CL, Benavente OR; SPS3 Investigators.

Int J Stroke. 2014 Jun;9(4):443-8. doi: 10.1111/ijs.12267. Epub 2014 Mar 24.

21.

Predictors of stroke recurrence in patients with recent lacunar stroke and response to interventions according to risk status: secondary prevention of small subcortical strokes trial.

Hart RG, Pearce LA, Bakheet MF, Benavente OR, Conwit RA, McClure LA, Talbert RL, Anderson DC.

J Stroke Cerebrovasc Dis. 2014 Apr;23(4):618-24. doi: 10.1016/j.jstrokecerebrovasdis.2013.05.021. Epub 2013 Jun 22.

22.

Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial.

SPS3 Study Group, Benavente OR, Coffey CS, Conwit R, Hart RG, McClure LA, Pearce LA, Pergola PE, Szychowski JM.

Lancet. 2013 Aug 10;382(9891):507-15. doi: 10.1016/S0140-6736(13)60852-1. Epub 2013 May 29. Erratum in: Lancet. 2013 Aug 10;382(9891):506. Coffey, C S [aded].

23.

Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials.

Palacio S, Hart RG, Pearce LA, Anderson DC, Sharma M, Birnbaum LA, Benavente OR.

Int J Stroke. 2015 Jul;10(5):686-91. doi: 10.1111/ijs.12050. Epub 2013 May 22.

24.

Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide.

Nisbet RM, Nuttall SD, Robert R, Caine JM, Dolezal O, Hattarki M, Pearce LA, Davydova N, Masters CL, Varghese JN, Streltsov VA.

Proteins. 2013 Oct;81(10):1748-58. doi: 10.1002/prot.24312. Epub 2013 Jul 22.

PMID:
23609990
25.

Aspirin therapy and risk of subdural hematoma: meta-analysis of randomized clinical trials.

Connolly BJ, Pearce LA, Kurth T, Kase CS, Hart RG.

J Stroke Cerebrovasc Dis. 2013 May;22(4):444-8. doi: 10.1016/j.jstrokecerebrovasdis.2013.01.007. Epub 2013 Feb 16.

PMID:
23422345
26.

Biochemical characterization of individual human glycosylated pro-insulin-like growth factor (IGF)-II and big-IGF-II isoforms associated with cancer.

Greenall SA, Bentley JD, Pearce LA, Scoble JA, Sparrow LG, Bartone NA, Xiao X, Baxter RC, Cosgrove LJ, Adams TE.

J Biol Chem. 2013 Jan 4;288(1):59-68. doi: 10.1074/jbc.M112.432013. Epub 2012 Nov 19.

27.

Cognitive impairment in lacunar strokes: the SPS3 trial.

Jacova C, Pearce LA, Costello R, McClure LA, Holliday SL, Hart RG, Benavente OR.

Ann Neurol. 2012 Sep;72(3):351-62. doi: 10.1002/ana.23733.

28.

Sex, stroke, and atrial fibrillation.

Hart RG, Eikelboom JW, Pearce LA.

Arch Neurol. 2012 Dec;69(12):1641-3. doi: 10.1001/archneurol.2012.2691.

PMID:
23007639
29.

Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.

Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA.

Ann Emerg Med. 2012 Dec;60(6):766-76. doi: 10.1016/j.annemergmed.2012.07.119. Epub 2012 Aug 31. Erratum in: Ann Emerg Med. 2013 Oct;62(4):302.

PMID:
22939607
30.

Effects of clopidogrel added to aspirin in patients with recent lacunar stroke.

SPS3 Investigators, Benavente OR, Hart RG, McClure LA, Szychowski JM, Coffey CS, Pearce LA.

N Engl J Med. 2012 Aug 30;367(9):817-25. doi: 10.1056/NEJMoa1204133.

31.

Effect of addition of clopidogrel to aspirin on mortality: systematic review of randomized trials.

Palacio S, Hart RG, Pearce LA, Benavente OR.

Stroke. 2012 Aug;43(8):2157-62. doi: 10.1161/STROKEAHA.112.656173. Review.

32.

Electrocardiographic differentiation of early repolarization from subtle anterior ST-segment elevation myocardial infarction.

Smith SW, Khalil A, Henry TD, Rosas M, Chang RJ, Heller K, Scharrer E, Ghorashi M, Pearce LA.

Ann Emerg Med. 2012 Jul;60(1):45-56.e2. doi: 10.1016/j.annemergmed.2012.02.015. Epub 2012 Apr 19.

PMID:
22520989
33.

Clinical features and racial/ethnic differences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.

White CL, Szychowski JM, Roldan A, Benavente MF, Pretell EJ, Del Brutto OH, Kase CS, Arauz A, Meyer BC, Meissner I, Demaerschalk BM, McClure LA, Coffey CS, Pearce LA, Conwit R, Irby LH, Peri K, Pergola PE, Hart RG, Benavente OR; SPS3 Investigators.

J Stroke Cerebrovasc Dis. 2013 Aug;22(6):764-74. doi: 10.1016/j.jstrokecerebrovasdis.2012.03.002. Epub 2012 Apr 17.

34.

Delta changes for optimizing clinical specificity and 60-day risk of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome utilizing the ADVIA Centaur TnI-Ultra assay.

Apple FS, Smith SW, Pearce LA, Murakami MM.

Clin Biochem. 2012 Jul;45(10-11):711-3. doi: 10.1016/j.clinbiochem.2012.02.030. Epub 2012 Mar 23.

PMID:
22465126
35.

Increased cardiac troponin I as measured by a high-sensitivity assay is associated with high odds of cardiovascular death: the Minnesota Heart Survey.

Apple FS, Steffen LM, Pearce LA, Murakami MM, Luepker RV.

Clin Chem. 2012 May;58(5):930-5. doi: 10.1373/clinchem.2011.179176. Epub 2012 Mar 19.

36.

Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by Sortase A-mediated protein ligation.

Madej MP, Coia G, Williams CC, Caine JM, Pearce LA, Attwood R, Bartone NA, Dolezal O, Nisbet RM, Nuttall SD, Adams TE.

Biotechnol Bioeng. 2012 Jun;109(6):1461-70. doi: 10.1002/bit.24407. Epub 2011 Dec 26.

PMID:
22170409
37.

Warfarin in atrial fibrillation patients with moderate chronic kidney disease.

Hart RG, Pearce LA, Asinger RW, Herzog CA.

Clin J Am Soc Nephrol. 2011 Nov;6(11):2599-604. doi: 10.2215/CJN.02400311. Epub 2011 Sep 8.

38.

Sleep apnea and white matter disease in hypertensive patients: a case series.

Kiernan TE, Capampangan DJ, Hickey MG, Pearce LA, Aguilar MI.

Neurologist. 2011 Sep;17(5):289-91. doi: 10.1097/NRL.0b013e31821a25d6.

PMID:
21881475
39.

Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin I concentrations.

Apple FS, Smith SW, Pearce LA, Schulz KM, Ler R, Murakami MM.

Clin Chem. 2011 Apr;57(4):603-8. doi: 10.1373/clinchem.2010.158014. Epub 2011 Jan 24.

40.

Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.

Robert R, Streltsov VA, Newman J, Pearce LA, Wark KL, Dolezal O.

Protein Sci. 2010 Feb;19(2):299-308. doi: 10.1002/pro.312.

41.

Current status of stroke risk stratification in patients with atrial fibrillation.

Hart RG, Pearce LA.

Stroke. 2009 Jul;40(7):2607-10. doi: 10.1161/STROKEAHA.109.549428. Epub 2009 May 21. Review. No abstract available.

PMID:
19461020
42.

Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events.

Apple FS, Pearce LA, Smith SW, Kaczmarek JM, Murakami MM.

Clin Chem. 2009 May;55(5):930-7. doi: 10.1373/clinchem.2008.114728. Epub 2009 Mar 19.

43.

Neuroprotection trials in Parkinson's disease: systematic review.

Hart RG, Pearce LA, Ravina BM, Yaltho TC, Marler JR.

Mov Disord. 2009 Apr 15;24(5):647-54. doi: 10.1002/mds.22432. Review.

PMID:
19117366
44.

Kinetic screening of antibody-Im7 conjugates by capture on a colicin E7 DNase domain using optical biosensors.

Hosse RJ, Tay L, Hattarki MK, Pontes-Braz L, Pearce LA, Nuttall SD, Dolezal O.

Anal Biochem. 2009 Feb 15;385(2):346-57. doi: 10.1016/j.ab.2008.11.026. Epub 2008 Nov 27.

PMID:
19073134
45.

Assessment of the multiple-biomarker approach for diagnosis of myocardial infarction in patients presenting with symptoms suggestive of acute coronary syndrome.

Apple FS, Smith SW, Pearce LA, Murakami MM.

Clin Chem. 2009 Jan;55(1):93-100. doi: 10.1373/clinchem.2008.102905. Epub 2008 Nov 21.

46.

Use of the Centaur TnI-Ultra assay for detection of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome.

Apple FS, Smith SW, Pearce LA, Ler R, Murakami MM.

Clin Chem. 2008 Apr;54(4):723-8. doi: 10.1373/clinchem.2007.097162. Epub 2008 Jan 31.

47.

Use of the bioMérieux VIDAS troponin I ultra assay for the diagnosis of myocardial infarction and detection of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome.

Apple FS, Smith SW, Pearce LA, Ler R, Murakami MM, Benoit MO, Levy C, Dumas C, Paul JL.

Clin Chim Acta. 2008 Apr;390(1-2):72-5. doi: 10.1016/j.cca.2007.12.016. Epub 2008 Jan 11.

PMID:
18230357
48.

Adjusted-dose warfarin versus aspirin for preventing stroke in patients with atrial fibrillation.

Hart RG, Pearce LA, Aguilar MI.

Ann Intern Med. 2007 Oct 16;147(8):590-2. No abstract available.

PMID:
17938402
49.
50.

Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.

Hart RG, Pearce LA, Aguilar MI.

Ann Intern Med. 2007 Jun 19;146(12):857-67.

PMID:
17577005

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