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Items: 40

1.

Structure of a hyperthermostable dimeric archaeal Rubisco from Hyperthermus butylicus.

Bundela R, Keown J, Watkin S, Pearce FG.

Acta Crystallogr D Struct Biol. 2019 Jun 1;75(Pt 6):536-544. doi: 10.1107/S2059798319006466. Epub 2019 May 28.

PMID:
31205016
2.

An unexpected sticking point for carboxysome assembly.

Pearce FG.

J Biol Chem. 2019 Feb 22;294(8):2604-2605. doi: 10.1074/jbc.H119.007530.

3.

Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus.

Davies JS, Coombes D, Horne CR, Pearce FG, Friemann R, North RA, Dobson RCJ.

FEBS Lett. 2019 Jan;593(1):52-66. doi: 10.1002/1873-3468.13289. Epub 2018 Nov 26.

PMID:
30411345
4.

A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins.

Keown JR, Black MM, Ferron A, Yap M, Barnett MJ, Pearce FG, Stoye JP, Goldstone DC.

J Biol Chem. 2018 Nov 23;293(47):18378-18386. doi: 10.1074/jbc.RA118.004202. Epub 2018 Oct 3.

5.

Self-assembly of toroidal proteins explored using native mass spectrometry.

Yewdall NA, Allison TM, Pearce FG, Robinson CV, Gerrard JA.

Chem Sci. 2018 Jun 18;9(28):6099-6106. doi: 10.1039/c8sc01379a. eCollection 2018 Jul 28.

6.

Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications.

Valegård K, Andralojc PJ, Haslam RP, Pearce FG, Eriksen GK, Madgwick PJ, Kristoffersen AK, van Lun M, Klein U, Eilertsen HC, Parry MAJ, Andersson I.

J Biol Chem. 2018 Aug 24;293(34):13033-13043. doi: 10.1074/jbc.RA118.003518. Epub 2018 Jun 20.

PMID:
29925588
7.

Immobilization of tobacco etch virus (TEV) protease on a high surface area protein nanofibril scaffold.

Raynes JK, Domigan LJ, Pearce FG, Gerrard JA.

Biotechnol Prog. 2018 Nov;34(6):1506-1512. doi: 10.1002/btpr.2670. Epub 2018 Sep 8.

PMID:
29882251
8.

Quaternary structure influences the peroxidase activity of peroxiredoxin 3.

Yewdall NA, Peskin AV, Hampton MB, Goldstone DC, Pearce FG, Gerrard JA.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):558-563. doi: 10.1016/j.bbrc.2018.02.093. Epub 2018 Feb 10.

PMID:
29438714
9.

Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.

Fagerlund RD, Wilkinson ME, Klykov O, Barendregt A, Pearce FG, Kieper SN, Maxwell HWR, Capolupo A, Heck AJR, Krause KL, Bostina M, Scheltema RA, Staals RHJ, Fineran PC.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5122-E5128. doi: 10.1073/pnas.1618421114. Epub 2017 Jun 13.

10.

Archaeal Lsm rings as stable self-assembling tectons for protein nanofabrication.

Wason A, Pearce FG, Gerrard JA, Mabbutt BC.

Biochem Biophys Res Commun. 2017 Jul 29;489(3):326-331. doi: 10.1016/j.bbrc.2017.05.129. Epub 2017 May 27.

PMID:
28559137
11.

Allelic Dropout During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci.

Stevens AJ, Taylor MG, Pearce FG, Kennedy MA.

G3 (Bethesda). 2017 Mar 10;7(3):1019-1025. doi: 10.1534/g3.116.038687.

12.

Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.

North RA, Watson AJ, Pearce FG, Muscroft-Taylor AC, Friemann R, Fairbanks AJ, Dobson RC.

FEBS Lett. 2016 Dec;590(23):4414-4428. doi: 10.1002/1873-3468.12462. Epub 2016 Nov 7.

13.

Structure and Function of Cyanobacterial DHDPS and DHDPR.

Christensen JB, Soares da Costa TP, Faou P, Pearce FG, Panjikar S, Perugini MA.

Sci Rep. 2016 Nov 15;6:37111. doi: 10.1038/srep37111.

14.

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

Cree SL, Fredericks R, Miller A, Pearce FG, Filichev V, Fee C, Kennedy MA.

FEBS Lett. 2016 Sep;590(17):2870-83. doi: 10.1002/1873-3468.12331. Epub 2016 Aug 11.

15.

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

Chen K, Dobson RC, Lucet IS, Young SN, Pearce FG, Blewitt ME, Murphy JM.

Biochem J. 2016 Jun 15;473(12):1733-44. doi: 10.1042/BCJ20160189. Epub 2016 Apr 8.

PMID:
27059856
16.
17.

Peroxiredoxin is a versatile self-assembling tecton for protein nanotechnology.

Phillips AJ, Littlejohn J, Yewdall NA, Zhu T, Valéry C, Pearce FG, Mitra AK, Radjainia M, Gerrard JA.

Biomacromolecules. 2014 May 12;15(5):1871-81. doi: 10.1021/bm500261u. Epub 2014 May 1.

PMID:
24749984
18.

From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae.

Dogovski C, Gorman MA, Ketaren NE, Praszkier J, Zammit LM, Mertens HD, Bryant G, Yang J, Griffin MD, Pearce FG, Gerrard JA, Jameson GB, Parker MW, Robins-Browne RM, Perugini MA.

PLoS One. 2013 Dec 13;8(12):e83419. doi: 10.1371/journal.pone.0083419. eCollection 2013.

19.

Small oligomers of ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase are required for biological activity.

Keown JR, Griffin MD, Mertens HD, Pearce FG.

J Biol Chem. 2013 Jul 12;288(28):20607-15. doi: 10.1074/jbc.M113.466383. Epub 2013 May 29.

20.

Aggregation and fibrillogenesis of proteins not associated with disease: a few case studies.

Lassé M, Gerrard JA, Pearce FG.

Subcell Biochem. 2012;65:253-70. doi: 10.1007/978-94-007-5416-4_11. Review.

PMID:
23225007
21.

Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana.

Griffin MD, Billakanti JM, Wason A, Keller S, Mertens HD, Atkinson SC, Dobson RC, Perugini MA, Gerrard JA, Pearce FG.

PLoS One. 2012;7(7):e40318. doi: 10.1371/journal.pone.0040318. Epub 2012 Jul 5.

22.

Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.

Atkinson SC, Dogovski C, Downton MT, Pearce FG, Reboul CF, Buckle AM, Gerrard JA, Dobson RC, Wagner J, Perugini MA.

PLoS One. 2012;7(6):e38318. doi: 10.1371/journal.pone.0038318. Epub 2012 Jun 25.

23.

Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana.

Griffin MD, Billakanti JM, Gerrard JA, Dobson RC, Pearce FG.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1386-90. doi: 10.1107/S1744309111033276. Epub 2011 Oct 27.

24.

Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization.

Pearce FG, Dobson RC, Jameson GB, Perugini MA, Gerrard JA.

Biochim Biophys Acta. 2011 Dec;1814(12):1900-9. doi: 10.1016/j.bbapap.2011.07.016. Epub 2011 Jul 22.

PMID:
21803176
25.

Immobilization of organophosphate hydrolase on an amyloid fibril nanoscaffold: towards bioremediation and chemical detoxification.

Raynes JK, Pearce FG, Meade SJ, Gerrard JA.

Biotechnol Prog. 2011 Mar-Apr;27(2):360-7. doi: 10.1002/btpr.518. Epub 2010 Nov 23.

PMID:
21485029
26.

Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine.

Muscroft-Taylor AC, Catchpole RJ, Dobson RC, Pearce FG, Perugini MA, Gerrard JA.

Arch Biochem Biophys. 2010 Nov 15;503(2):202-6. doi: 10.1016/j.abb.2010.08.009. Epub 2010 Aug 13.

PMID:
20709017
27.

Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

Dommaraju S, Gorman MA, Dogovski C, Pearce FG, Gerrard JA, Dobson RC, Parker MW, Perugini MA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):57-60. doi: 10.1107/S1744309109047964. Epub 2009 Dec 25.

28.

Does domain swapping improve the stability of RNase A?

Pearce FG, Griffin MD, Gerrard JA.

Biochem Biophys Res Commun. 2009 Apr 24;382(1):114-8. doi: 10.1016/j.bbrc.2009.02.142. Epub 2009 Mar 3.

PMID:
19265683
29.

Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme.

Pearce FG, Dobson RC, Weber A, Lane LA, McCammon MG, Squire MA, Perugini MA, Jameson GB, Robinson CV, Gerrard JA.

Biochemistry. 2008 Nov 18;47(46):12108-17. doi: 10.1021/bi801094t. Epub 2008 Oct 21.

PMID:
18937497
30.

Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.

Dobson RC, Griffin MD, Devenish SR, Pearce FG, Hutton CA, Gerrard JA, Jameson GB, Perugini MA.

Protein Sci. 2008 Dec;17(12):2080-90. doi: 10.1110/ps.037440.108. Epub 2008 Sep 11.

31.

Evolution of quaternary structure in a homotetrameric enzyme.

Griffin MD, Dobson RC, Pearce FG, Antonio L, Whitten AE, Liew CK, Mackay JP, Trewhella J, Jameson GB, Perugini MA, Gerrard JA.

J Mol Biol. 2008 Jul 18;380(4):691-703. doi: 10.1016/j.jmb.2008.05.038. Epub 2008 May 22.

PMID:
18556019
32.

Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics.

Pearce FG, Sprissler C, Gerrard JA.

J Biochem. 2008 May;143(5):617-23. doi: 10.1093/jb/mvn012. Epub 2008 Feb 4.

PMID:
18250105
33.

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.

Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC.

Biochem J. 2008 Apr 15;411(2):351-60.

PMID:
18062777
34.

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

Mitsakos V, Dobson RC, Pearce FG, Devenish SR, Evans GL, Burgess BR, Perugini MA, Gerrard JA, Hutton CA.

Bioorg Med Chem Lett. 2008 Jan 15;18(2):842-4. Epub 2007 Nov 13.

PMID:
18054225
35.

Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing.

Pearce FG, Mackintosh SH, Gerrard JA.

J Agric Food Chem. 2007 Jan 24;55(2):318-22.

PMID:
17227060
36.

Dihydrodipicolinate synthase from Thermotoga maritima.

Pearce FG, Perugini MA, McKerchar HJ, Gerrard JA.

Biochem J. 2006 Dec 1;400(2):359-66.

38.

Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase.

Dobson RC, Devenish SR, Turner LA, Clifford VR, Pearce FG, Jameson GB, Gerrard JA.

Biochemistry. 2005 Oct 4;44(39):13007-13.

PMID:
16185069
39.

Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde.

Dobson RC, Gerrard JA, Pearce FG.

Biochem J. 2004 Feb 1;377(Pt 3):757-62.

40.

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