Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 163

1.

Trib1 regulates T cell differentiation during chronic infection by restraining the effector program.

Rome KS, Stein SJ, Kurachi M, Petrovic J, Schwartz GW, Mack EA, Uljon S, Wu WW, DeHart AG, McClory SE, Xu L, Gimotty PA, Blacklow SC, Faryabi RB, Wherry EJ, Jordan MS, Pear WS.

J Exp Med. 2020 May 4;217(5). pii: e20190888. doi: 10.1084/jem.20190888.

PMID:
32150623
2.

TooManyCells identifies and visualizes relationships of single-cell clades.

Schwartz GW, Zhou Y, Petrovic J, Fasolino M, Xu L, Shaffer SM, Pear WS, Vahedi G, Faryabi RB.

Nat Methods. 2020 Mar 2. doi: 10.1038/s41592-020-0748-5. [Epub ahead of print]

PMID:
32123397
3.

Transcription factor and cytokine regulation of eosinophil lineage commitment.

Mack EA, Pear WS.

Curr Opin Hematol. 2020 Jan;27(1):27-33. doi: 10.1097/MOH.0000000000000552.

PMID:
31688456
4.

Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program.

Mack EA, Stein SJ, Rome KS, Xu L, Wertheim GB, Melo RCN, Pear WS.

Blood. 2019 May 30;133(22):2413-2426. doi: 10.1182/blood.2018872218. Epub 2019 Mar 27.

PMID:
30917956
5.

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Petrovic J, Zhou Y, Fasolino M, Goldman N, Schwartz GW, Mumbach MR, Nguyen SC, Rome KS, Sela Y, Zapataro Z, Blacklow SC, Kruhlak MJ, Shi J, Aster JC, Joyce EF, Little SC, Vahedi G, Pear WS, Faryabi RB.

Mol Cell. 2019 Mar 21;73(6):1174-1190.e12. doi: 10.1016/j.molcel.2019.01.006. Epub 2019 Feb 7.

6.

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds.

Guerrero-Juarez CF, Dedhia PH, Jin S, Ruiz-Vega R, Ma D, Liu Y, Yamaga K, Shestova O, Gay DL, Yang Z, Kessenbrock K, Nie Q, Pear WS, Cotsarelis G, Plikus MV.

Nat Commun. 2019 Feb 8;10(1):650. doi: 10.1038/s41467-018-08247-x.

7.

Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm.

Kong G, You X, Wen Z, Chang YI, Qian S, Ranheim EA, Letson C, Zhang X, Zhou Y, Liu Y, Rajagopalan A, Zhang J, Stieglitz E, Loh M, Hofmann I, Yang D, Zhong X, Padron E, Zhou L, Pear WS, Zhang J.

Leukemia. 2019 Mar;33(3):671-685. doi: 10.1038/s41375-018-0248-0. Epub 2018 Sep 11.

8.

Can genetics resolve what Notch does in HSCs?

Maillard I, Pear WS.

Blood. 2018 Apr 12;131(15):1633-1635. doi: 10.1182/blood-2018-02-829069. No abstract available.

9.

Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells.

Johnson JL, Georgakilas G, Petrovic J, Kurachi M, Cai S, Harly C, Pear WS, Bhandoola A, Wherry EJ, Vahedi G.

Immunity. 2018 Feb 20;48(2):243-257.e10. doi: 10.1016/j.immuni.2018.01.012.

10.

MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.

Pajcini KV, Xu L, Shao L, Petrovic J, Palasiewicz K, Ohtani Y, Bailis W, Lee C, Wertheim GB, Mani R, Muthusamy N, Li Y, Meijerink JPP, Blacklow SC, Faryabi RB, Cherry S, Pear WS.

Sci Signal. 2017 Nov 14;10(505). pii: eaam6846. doi: 10.1126/scisignal.aam6846.

11.

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.

12.

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.

Choi SH, Severson E, Pear WS, Liu XS, Aster JC, Blacklow SC.

PLoS One. 2017 Oct 12;12(10):e0185762. doi: 10.1371/journal.pone.0185762. eCollection 2017.

13.

Genome-wide identification and characterization of Notch transcription complex-binding sequence-paired sites in leukemia cells.

Severson E, Arnett KL, Wang H, Zang C, Taing L, Liu H, Pear WS, Shirley Liu X, Blacklow SC, Aster JC.

Sci Signal. 2017 May 2;10(477). pii: eaag1598. doi: 10.1126/scisignal.aag1598.

14.

Regeneration of fat cells from myofibroblasts during wound healing.

Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G.

Science. 2017 Feb 17;355(6326):748-752. doi: 10.1126/science.aai8792. Epub 2017 Jan 5.

15.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Kobayashi M, Nabinger SC, Bai Y, Yoshimoto M, Gao R, Chen S, Yao C, Dong Y, Zhang L, Rodriguez S, Yashiro-Ohtani Y, Pear WS, Carlesso N, Yoder MC, Kapur R, Kaplan MH, Daniel Lacorazza H, Zhang ZY, Liu Y.

Stem Cells. 2017 Apr;35(4):1053-1064. doi: 10.1002/stem.2559. Epub 2017 Jan 19.

16.

The Varied Roles of Notch in Cancer.

Aster JC, Pear WS, Blacklow SC.

Annu Rev Pathol. 2017 Jan 24;12:245-275. doi: 10.1146/annurev-pathol-052016-100127. Epub 2016 Dec 5. Review.

17.

High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia.

Chiang MY, Wang Q, Gormley AC, Stein SJ, Xu L, Shestova O, Aster JC, Pear WS.

Blood. 2016 Nov 3;128(18):2229-2240. Epub 2016 Sep 26.

18.

Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand.

Greene M, Lai Y, Pajcini K, Bailis W, Pear WS, Lancaster E.

PLoS One. 2016 Sep 13;11(9):e0161157. doi: 10.1371/journal.pone.0161157. eCollection 2016.

19.

Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.

Stein SJ, Mack EA, Rome KS, Pajcini KV, Ohtani T, Xu L, Li Y, Meijerink JP, Faryabi RB, Pear WS.

PLoS One. 2016 May 18;11(5):e0155408. doi: 10.1371/journal.pone.0155408. eCollection 2016.

20.

Structural Basis for Substrate Selectivity of the E3 Ligase COP1.

Uljon S, Xu X, Durzynska I, Stein S, Adelmant G, Marto JA, Pear WS, Blacklow SC.

Structure. 2016 May 3;24(5):687-696. doi: 10.1016/j.str.2016.03.002. Epub 2016 Mar 31.

Supplemental Content

Support Center