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Items: 38


Synthetic Antigen Gels as Practical Controls for Standardized and Quantitative Immunohistochemistry.

Hötzel KJ, Havnar CA, Ngu HV, Rost S, Liu SD, Rangell LK, Peale FV.

J Histochem Cytochem. 2019 May;67(5):309-334. doi: 10.1369/0022155419832002. Epub 2019 Mar 18.


Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors.

Italiano A, Infante JR, Shapiro GI, Moore KN, LoRusso PM, Hamilton E, Cousin S, Toulmonde M, Postel-Vinay S, Tolaney S, Blackwood EM, Mahrus S, Peale FV, Lu X, Moein A, Epler J, DuPree K, Tagen M, Murray ER, Schutzman JL, Lauchle JO, Hollebecque A, Soria JC.

Ann Oncol. 2018 Feb 23. doi: 10.1093/annonc/mdy076. [Epub ahead of print]


Monitoring and Targeting Anti-VEGF Induced Hypoxia within the Viable Tumor by 19F-MRI and Multispectral Analysis.

Shi Y, Oeh J, Hitz A, Hedehus M, Eastham-Anderson J, Peale FV Jr, Hamilton P, O'Brien T, Sampath D, Carano RAD.

Neoplasia. 2017 Nov;19(11):950-959. doi: 10.1016/j.neo.2017.07.010. Epub 2017 Oct 6.


Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors.

Infante JR, Hollebecque A, Postel-Vinay S, Bauer TM, Blackwood EM, Evangelista M, Mahrus S, Peale FV, Lu X, Sahasranaman S, Zhu R, Chen Y, Ding X, Murray ER, Schutzman JL, Lauchle JO, Soria JC, LoRusso PM.

Clin Cancer Res. 2017 May 15;23(10):2423-2432. doi: 10.1158/1078-0432.CCR-16-1782. Epub 2016 Nov 4.


Mapping in vivo tumor oxygenation within viable tumor by 19F-MRI and multispectral analysis.

Shi Y, Oeh J, Eastham-Anderson J, Yee S, Finkle D, Peale FV Jr, Ross J, Hedehus M, van Bruggen N, Venook R, Ross S, Sampath D, Carano RA.

Neoplasia. 2013 Nov;15(11):1241-50.


An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy.

Chung AS, Wu X, Zhuang G, Ngu H, Kasman I, Zhang J, Vernes JM, Jiang Z, Meng YG, Peale FV, Ouyang W, Ferrara N.

Nat Med. 2013 Sep;19(9):1114-23. doi: 10.1038/nm.3291. Epub 2013 Aug 4.


Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF-induced neutrophil recruitment.

Phan VT, Wu X, Cheng JH, Sheng RX, Chung AS, Zhuang G, Tran C, Song Q, Kowanetz M, Sambrone A, Tan M, Meng YG, Jackson EL, Peale FV, Junttila MR, Ferrara N.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6079-84. doi: 10.1073/pnas.1303302110. Epub 2013 Mar 25.


Navitoclax (ABT-263) reduces Bcl-x(L)-mediated chemoresistance in ovarian cancer models.

Wong M, Tan N, Zha J, Peale FV, Yue P, Fairbrother WJ, Belmont LD.

Mol Cancer Ther. 2012 Apr;11(4):1026-35. doi: 10.1158/1535-7163.MCT-11-0693. Epub 2012 Feb 1.


Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes.

Kowanetz M, Wu X, Lee J, Tan M, Hagenbeek T, Qu X, Yu L, Ross J, Korsisaari N, Cao T, Bou-Reslan H, Kallop D, Weimer R, Ludlam MJ, Kaminker JS, Modrusan Z, van Bruggen N, Peale FV, Carano R, Meng YG, Ferrara N.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21248-55. doi: 10.1073/pnas.1015855107. Epub 2010 Nov 16.


Vessel imaging with viable tumor analysis for quantification of tumor angiogenesis.

Ungersma SE, Pacheco G, Ho C, Yee SF, Ross J, van Bruggen N, Peale FV Jr, Ross S, Carano RA.

Magn Reson Med. 2010 Jun;63(6):1637-47. doi: 10.1002/mrm.22442. Erratum in: Magn Reson Med. 2011 Mar;65(3):889. Magn Reson Med. 2012 Nov;68(5):1681-2. Corrected and republished in: Magn Reson Med. 2011 Mar;65(3):889-99.


Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging.

O'Connor JP, Carano RA, Clamp AR, Ross J, Ho CC, Jackson A, Parker GJ, Rose CJ, Peale FV, Friesenhahn M, Mitchell CL, Watson Y, Roberts C, Hope L, Cheung S, Reslan HB, Go MA, Pacheco GJ, Wu X, Cao TC, Ross S, Buonaccorsi GA, Davies K, Hasan J, Thornton P, del Puerto O, Ferrara N, van Bruggen N, Jayson GC.

Clin Cancer Res. 2009 Nov 1;15(21):6674-82. doi: 10.1158/1078-0432.CCR-09-0731. Epub 2009 Oct 27.


Reactive hyperemia and BOLD MRI demonstrate that VEGF inhibition, age, and atherosclerosis adversely affect functional recovery in a murine model of peripheral artery disease.

Greve JM, Williams SP, Bernstein LJ, Goldman H, Peale FV Jr, Bunting S, van Bruggen N.

J Magn Reson Imaging. 2008 Oct;28(4):996-1004. doi: 10.1002/jmri.21517.


Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1.

Korsisaari N, Ross J, Wu X, Kowanetz M, Pal N, Hall L, Eastham-Anderson J, Forrest WF, Van Bruggen N, Peale FV, Ferrara N.

Clin Cancer Res. 2008 Jan 1;14(1):249-58. doi: 10.1158/1078-0432.CCR-07-1552.


Bv8 regulates myeloid-cell-dependent tumour angiogenesis.

Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N.

Nature. 2007 Dec 6;450(7171):825-31.


Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice.

Korsisaari N, Kasman IM, Forrest WF, Pal N, Bai W, Fuh G, Peale FV, Smits R, Ferrara N.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10625-30. Epub 2007 Jun 6.


Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease.

Greve JM, Chico TJ, Goldman H, Bunting S, Peale FV Jr, Daugherty A, van Bruggen N, Williams SP.

J Magn Reson Imaging. 2006 Nov;24(5):1124-32.


Quantitative in situ hybridization of tissue microarrays.

Jubb AM, Pham TQ, Frantz GD, Peale FV Jr, Hillan KJ.

Methods Mol Biol. 2006;326:255-64. Review.


Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma.

Tejada ML, Yu L, Dong J, Jung K, Meng G, Peale FV, Frantz GD, Hall L, Liang X, Gerber HP, Ferrara N.

Clin Cancer Res. 2006 May 1;12(9):2676-88.


Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

Liang WC, Wu X, Peale FV, Lee CV, Meng YG, Gutierrez J, Fu L, Malik AK, Gerber HP, Ferrara N, Fuh G.

J Biol Chem. 2006 Jan 13;281(2):951-61. Epub 2005 Nov 7.


Human endocrine gland-derived vascular endothelial growth factor: expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis.

Samson M, Peale FV Jr, Frantz G, Rioux-Leclercq N, Rajpert-De Meyts E, Ferrara N.

J Clin Endocrinol Metab. 2004 Aug;89(8):4078-88.


Expression of vascular endothelial growth factor, hypoxia inducible factor 1alpha, and carbonic anhydrase IX in human tumours.

Jubb AM, Pham TQ, Hanby AM, Frantz GD, Peale FV, Wu TD, Koeppen HW, Hillan KJ.

J Clin Pathol. 2004 May;57(5):504-12.


Stanniocalcin 1 is an autocrine modulator of endothelial angiogenic responses to hepatocyte growth factor.

Zlot C, Ingle G, Hongo J, Yang S, Sheng Z, Schwall R, Paoni N, Wang F, Peale FV Jr, Gerritsen ME.

J Biol Chem. 2003 Nov 28;278(48):47654-9. Epub 2003 Sep 17.


Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization.

Jubb AM, Landon TH, Burwick J, Pham TQ, Frantz GD, Cairns B, Quirke P, Peale FV, Hillan KJ.

J Pathol. 2003 Aug;200(5):577-88.


Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover.

Street J, Bao M, deGuzman L, Bunting S, Peale FV Jr, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, van Bruggen N, Redmond HP, Carano RA, Filvaroff EH.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9656-61. Epub 2002 Jul 12.


Dobutamine stress cine-MRI of cardiac function in the hearts of adult cardiomyocyte-specific VEGF knockout mice.

Williams SP, Gerber HP, Giordano FJ, Peale FV Jr, Bernstein LJ, Bunting S, Chien KR, Ferrara N, van Bruggen N.

J Magn Reson Imaging. 2001 Oct;14(4):374-82.


Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays.

Frantz GD, Pham TQ, Peale FV Jr, Hillan KJ.

J Pathol. 2001 Sep;195(1):87-96. Review.


Gene profiling techniques and their application in angiogenesis and vascular development.

Peale FV Jr, Gerritsen ME.

J Pathol. 2001 Sep;195(1):7-19. Review.


FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family.

Holcomb IN, Kabakoff RC, Chan B, Baker TW, Gurney A, Henzel W, Nelson C, Lowman HB, Wright BD, Skelton NJ, Frantz GD, Tumas DB, Peale FV Jr, Shelton DL, Hébert CC.

EMBO J. 2000 Aug 1;19(15):4046-55.


Expression of novel potassium channels in the chick basilar papilla.

Mason K, Peale FV Jr, Stone JS, Rubel EW, Bothwell M.

Hear Res. 1998 Nov;125(1-2):120-30.


Characterization of CMIX, a chicken homeobox gene related to the Xenopus gene mix.1.

Peale FV Jr, Sugden L, Bothwell M.

Mech Dev. 1998 Jul;75(1-2):167-70.


Multiplex display polymerase chain reaction amplifies and resolves related sequences sharing a single moderately conserved domain.

Peale FV Jr, Mason K, Hunter AW, Bothwell M.

Anal Biochem. 1998 Feb 15;256(2):158-68.


Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro.

Klinge CM, Peale FV Jr, Hilf R, Bambara RA, Zain S.

Cancer Res. 1992 Mar 1;52(5):1073-81.


A microtiter well assay for quantitative measurement of estrogen receptor binding to estrogen-responsive elements.

Ludwig LB, Klinge CM, Peale FV Jr, Bambara RA, Zain S, Hilf R.

Mol Endocrinol. 1990 Jul;4(7):1027-33.


Rapid purification of the estrogen receptor by sequence-specific DNA affinity chromatography.

Peale FV Jr, Ishibe Y, Klinge CM, Zain S, Hilf R, Bambara RA.

Biochemistry. 1989 Oct 31;28(22):8671-5.


Properties of a high-affinity DNA binding site for estrogen receptor.

Peale FV Jr, Ludwig LB, Zain S, Hilf R, Bambara RA.

Proc Natl Acad Sci U S A. 1988 Feb;85(4):1038-42.


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