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Items: 1 to 50 of 172

1.

Proactive therapeutic drug monitoring (TDM) may be helpful in managing long-term treatment with linezolid safely: findings from a monocentric, prospective, open-label, interventional study.

Cojutti PG, Merelli M, Bassetti M, Pea F.

J Antimicrob Chemother. 2019 Aug 31. pii: dkz374. doi: 10.1093/jac/dkz374. [Epub ahead of print]

PMID:
31504570
2.

Reappraisal of Linezolid Dosing in Renal Impairment To Improve Safety.

Crass RL, Cojutti PG, Pai MP, Pea F.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00605-19. doi: 10.1128/AAC.00605-19. Print 2019 Aug.

PMID:
31109977
3.

Treatment of Candida infections with fluconazole in adult liver transplant recipients: Is TDM-guided dosing adaptation helpful?

Righi E, Carnelutti A, Baccarani U, Sartor A, Cojutti P, Bassetti M, Pea F.

Transpl Infect Dis. 2019 Aug;21(4):e13113. doi: 10.1111/tid.13113. Epub 2019 Jun 4.

PMID:
31106504
4.

Inter-laboratory analysis of Isavuconazole plasma concentration assays among European laboratories.

Pea F, Krause R, Müller C, Hennart B, Richardson M, Meinitzer A, Wiesen MHJ, Wiktorowicz T, Spickermann J, Henriksen AS.

Ther Drug Monit. 2019 Mar 31. doi: 10.1097/FTD.0000000000000632. [Epub ahead of print]

PMID:
30950933
5.
6.

Successful and safe long-term treatment of cerebral aspergillosis with high-dose voriconazole guided by therapeutic drug monitoring.

Cojutti PG, Merelli M, Allegri L, Damante G, Bassetti M, Pea F.

Br J Clin Pharmacol. 2019 Jan;85(1):266-269. doi: 10.1111/bcp.13789. Epub 2018 Nov 9.

PMID:
30414213
7.

Pharmacokinetics and drug metabolism of antibiotics in the elderly.

Pea F.

Expert Opin Drug Metab Toxicol. 2018 Oct;14(10):1087-1100. doi: 10.1080/17425255.2018.1528226. Epub 2018 Oct 10. Review.

PMID:
30251551
8.

Disposition of ceftobiprole during continuous venous-venous hemodiafiltration (CVVHDF) in a single critically ill patient.

Cojutti PG, Merelli M, De Stefanis P, Fregonese C, Lucchese F, Bassetti M, Pea F.

Eur J Clin Pharmacol. 2018 Dec;74(12):1671-1672. doi: 10.1007/s00228-018-2535-0. Epub 2018 Aug 10. No abstract available.

PMID:
30094703
9.

Population pharmacokinetics of fluconazole in liver transplantation: implications for target attainment for infections with Candida albicans and non-albicans spp.

Cojutti PG, Lugano M, Righi E, Della Rocca G, Bassetti M, Hope W, Pea F.

Eur J Clin Pharmacol. 2018 Nov;74(11):1449-1459. doi: 10.1007/s00228-018-2526-1. Epub 2018 Jul 21.

PMID:
30032414
10.

Co-administration of proton pump inhibitors and/or of steroids may be a risk factor for low trough concentrations of posaconazole delayed-released tablets in adult patients with haematological malignancies.

Cojutti PG, Candoni A, Lazzarotto D, Rabassi N, Fanin R, Hope W, Pea F.

Br J Clin Pharmacol. 2018 Nov;84(11):2544-2550. doi: 10.1111/bcp.13707. Epub 2018 Aug 19.

PMID:
29975796
11.

Procalcitonin-guided antibiotic therapy: an expert consensus.

Bartoletti M, Antonelli M, Bruno Blasi FA, Casagranda I, Chieregato A, Fumagalli R, Girardis M, Pieralli F, Plebani M, Rossolini GM, Sartelli M, Viaggi B, Viale P, Viscoli C, Pea F.

Clin Chem Lab Med. 2018 Jul 26;56(8):1223-1229. doi: 10.1515/cclm-2018-0259.

12.

Is meropenem MIC increase against KPC-producing Klebsiella pneumoniae correlated with increased resistance rates against other antimicrobials with Gram-negative activity?

Cojutti P, Sartor A, Bassetti M, Scarparo C, Pea F.

J Glob Antimicrob Resist. 2018 Sep;14:238-241. doi: 10.1016/j.jgar.2018.05.005. Epub 2018 Jul 9.

PMID:
29775786
13.

Higher than standard meropenem and linezolid dosages needed for appropriate treatment of an intracerebral hemorrhage patient with augmented renal clearance.

Cojutti PG, Barbarino C, De Monte A, Hope W, Pea F.

Eur J Clin Pharmacol. 2018 Aug;74(8):1091-1092. doi: 10.1007/s00228-018-2465-x. Epub 2018 Apr 29. No abstract available.

PMID:
29705821
14.

Valganciclovir Pharmacokinetics in Patients Receiving Oral Prophylaxis Following Kidney Transplantation and Model-Based Predictions of Optimal Dosing Regimens.

Tängdén T, Cojutti PG, Roberts JA, Pea F.

Clin Pharmacokinet. 2018 Nov;57(11):1399-1405. doi: 10.1007/s40262-018-0638-5.

PMID:
29546589
15.

Actoxumab + bezlotoxumab combination: what promise for Clostridium difficile treatment?

Posteraro B, Pea F, Masucci L, Posteraro P, Sanguinetti M.

Expert Opin Biol Ther. 2018 Apr;18(4):469-476. doi: 10.1080/14712598.2018.1452908. Epub 2018 Mar 15. Review.

PMID:
29534621
16.

Ceftolozane/tazobactam: place in therapy.

Giacobbe DR, Bassetti M, De Rosa FG, Del Bono V, Grossi PA, Menichetti F, Pea F, Rossolini GM, Tumbarello M, Viale P, Viscoli C; ISGRI-SITA (Italian Study Group on Resistant Infections of the Società Italiana Terapia Antinfettiva).

Expert Rev Anti Infect Ther. 2018 Apr;16(4):307-320. doi: 10.1080/14787210.2018.1447381. Epub 2018 Mar 9. Review.

17.

The current role of glycopeptides in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in not neutropenic adults: the viewpoint of a group of Italian experts.

Concia E, Viscoli C, Del Bono V, Giannella M, Bassetti M, De Rosa GF, Durante Mangoni E, Esposito S, Giusti M, Grossi P, Menichetti F, Pea F, Petrosillo N, Tumbarello M, Stefani S, Venditti M, Viale P; group of Italian Experts.

J Chemother. 2018 May;30(3):157-171. doi: 10.1080/1120009X.2017.1420610. Epub 2018 Jan 30.

PMID:
29380676
18.

Overview of antifungal dosing in invasive candidiasis.

Pea F, Lewis RE.

J Antimicrob Chemother. 2018 Jan 1;73(suppl_1):i33-i43. doi: 10.1093/jac/dkx447. Review.

PMID:
29304210
19.

Ceftolozane/tazobactam for the treatment of MDR Pseudomonas aeruginosa left ventricular assist device infection as a bridge to heart transplant.

Peghin M, Maiani M, Castaldo N, Givone F, Righi E, Lechiancole A, Sartor A, Pea F, Livi U, Bassetti M.

Infection. 2018 Apr;46(2):263-265. doi: 10.1007/s15010-017-1086-0. Epub 2017 Oct 31.

PMID:
29086895
20.

Population Pharmacokinetics and Dosing Considerations for the Use of Linezolid in Overweight and Obese Adult Patients.

Cojutti P, Pai MP, Pea F.

Clin Pharmacokinet. 2018 Aug;57(8):989-1000. doi: 10.1007/s40262-017-0606-5.

PMID:
29080937
21.

Clinical and pharmacokinetic drug evaluation of delafloxacin for the treatment of acute bacterial skin and skin structure infections.

Bassetti M, Pecori D, Cojutti P, Righi E, Pea F.

Expert Opin Drug Metab Toxicol. 2017 Nov;13(11):1193-1200. doi: 10.1080/17425255.2017.1386654. Epub 2017 Oct 14. Review.

PMID:
28988505
22.

β-Blockers and Diltiazem Combination-Bear in Mind the Risk of Heart Block.

Pea F.

JAMA Intern Med. 2017 Oct 1;177(10):1543-1544. doi: 10.1001/jamainternmed.2017.4765. No abstract available.

PMID:
28973279
23.

Pharmacodynamics of teicoplanin against MRSA.

Ramos-Martín V, Johnson A, McEntee L, Farrington N, Padmore K, Cojutti P, Pea F, Neely MN, Hope WW.

J Antimicrob Chemother. 2017 Dec 1;72(12):3382-3389. doi: 10.1093/jac/dkx289.

PMID:
28962026
24.

Successful treatment and FDG-PET/CT monitoring of HHV-6 encephalitis in a non-neutropenic patient: case report and literature review.

Righi E, Carnelutti A, Muser D, Zaja F, Lucchini E, Pea F, Di Gregorio F, Alavi A, Bassetti M.

J Neurovirol. 2017 Dec;23(6):908-912. doi: 10.1007/s13365-017-0566-4. Epub 2017 Aug 18.

PMID:
28822107
25.

Population Pharmacokinetics of High-Dose Continuous-Infusion Meropenem and Considerations for Use in the Treatment of Infections Due to KPC-Producing Klebsiella pneumoniae.

Cojutti P, Sartor A, Righi E, Scarparo C, Bassetti M, Pea F.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00794-17. doi: 10.1128/AAC.00794-17. Print 2017 Oct.

26.

Intracellular Pharmacokinetics of Antibacterials and Their Clinical Implications.

Pea F.

Clin Pharmacokinet. 2018 Feb;57(2):177-189. doi: 10.1007/s40262-017-0572-y. Review.

PMID:
28639230
27.

Population pharmacokinetics and dosing considerations for the use of daptomycin in adult patients with haematological malignancies.

Cojutti PG, Candoni A, Ramos-Martin V, Lazzarotto D, Zannier ME, Fanin R, Hope W, Pea F.

J Antimicrob Chemother. 2017 Aug 1;72(8):2342-2350. doi: 10.1093/jac/dkx140.

PMID:
28575511
28.

Limited sampling strategies for determining the area under the plasma concentration-time curve for isoniazid might be a valuable approach for optimizing treatment in adult patients with tuberculosis.

Cojutti P, Giangreco M, Isola M, Pea F.

Int J Antimicrob Agents. 2017 Jul;50(1):23-28. doi: 10.1016/j.ijantimicag.2017.01.036. Epub 2017 May 8.

PMID:
28495479
29.
30.

Monitoring Polypharmacy in Healthcare Systems Through a Multi-Setting Survey: Should We Put More Attention on Long Term Care Facilities?

Arnoldo L, Cattani G, Cojutti P, Pea F, Brusaferro S.

J Public Health Res. 2016 Dec 9;5(3):745. doi: 10.4081/jphr.2016.745. eCollection 2016 Dec 9.

31.

Population Pharmacokinetics and Pharmacodynamics of Levofloxacin in Acutely Hospitalized Older Patients with Various Degrees of Renal Function.

Cojutti PG, Ramos-Martin V, Schiavon I, Rossi P, Baraldo M, Hope W, Pea F.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02134-16. doi: 10.1128/AAC.02134-16. Print 2017 Mar.

32.

Might real-time pharmacokinetic/pharmacodynamic optimisation of high-dose continuous-infusion meropenem improve clinical cure in infections caused by KPC-producing Klebsiella pneumoniae?

Pea F, Della Siega P, Cojutti P, Sartor A, Crapis M, Scarparo C, Bassetti M.

Int J Antimicrob Agents. 2017 Feb;49(2):255-258. doi: 10.1016/j.ijantimicag.2016.10.018. Epub 2016 Dec 8.

PMID:
28012683
33.

Methicillin-resistant Staphylococcus aureus infections: A review of the currently available treatment options.

Purrello SM, Garau J, Giamarellos E, Mazzei T, Pea F, Soriano A, Stefani S.

J Glob Antimicrob Resist. 2016 Dec;7:178-186. doi: 10.1016/j.jgar.2016.07.010. Epub 2016 Sep 5. Review.

PMID:
27889013
36.

Practical concept of pharmacokinetics/pharmacodynamics in the management of skin and soft tissue infections.

Pea F.

Curr Opin Infect Dis. 2016 Apr;29(2):153-9. doi: 10.1097/QCO.0000000000000256. Review.

PMID:
26836376
37.

Might isoniazid plasma exposure be a valuable predictor of drug-related hepatotoxicity risk among adult patients with TB?

Cojutti P, Duranti S, Isola M, Baraldo M, Viale P, Bassetti M, Pea F.

J Antimicrob Chemother. 2016 May;71(5):1323-9. doi: 10.1093/jac/dkv490. Epub 2016 Jan 31.

PMID:
26832752
38.

Immunologic and Pharmacologic Aspects in an Elderly Recipient of Liver Transplant With Pulmonary Aspergillosis and Multiple Comorbidities.

Righi E, Ivaldi F, Carnelutti A, Tomkova L, Villa G, Sartor A, Soardo G, Baccarani U, Pea F, Bassetti M.

Exp Clin Transplant. 2016 Oct;14(5):567-570. doi: 10.6002/ect.2014.0127. Epub 2016 Jan 8.

39.

Does Critical Illness Change Levofloxacin Pharmacokinetics?

Roberts JA, Cotta MO, Cojutti P, Lugano M, Della Rocca G, Pea F.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1459-63. doi: 10.1128/AAC.02610-15.

40.

Reply: Implementation of a Meningitis Care Bundle in the Emergency Room Reduces Mortality Associated With Acute Bacterial Meningitis.

Viale P, Giannella M, Tedeschi S, Bartoletti M, Pea F.

Ann Pharmacother. 2016 Feb;50(2):153. doi: 10.1177/1060028015615881. Epub 2015 Nov 20. No abstract available.

PMID:
26590386
41.

Variability of Voriconazole Trough Levels in Haematological Patients: Influence of Comedications with cytochrome P450(CYP) Inhibitors and/or with CYP Inhibitors plus CYP Inducers.

Cojutti P, Candoni A, Forghieri F, Isola M, Zannier ME, Bigliardi S, Luppi M, Fanin R, Pea F.

Basic Clin Pharmacol Toxicol. 2016 Jun;118(6):474-9. doi: 10.1111/bcpt.12530. Epub 2015 Dec 28.

42.

A 1 year retrospective audit of quality indicators of clinical pharmacological advice for personalized linezolid dosing: one stone for two birds?

Pea F, Cojutti P, Dose L, Baraldo M.

Br J Clin Pharmacol. 2016 Feb;81(2):341-8. doi: 10.1111/bcp.12806. Epub 2015 Dec 5.

43.

Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia.

Pea F, Cojutti P, Tursi V, Livi U, Baraldo M.

Transpl Infect Dis. 2015 Dec;17(6):926-8. doi: 10.1111/tid.12446. Epub 2015 Oct 28. No abstract available.

PMID:
26296391
44.

Is empiric daptomycin effective in reducing mortality in Staphylococcus aureus bacteraemia? A real-life experience.

Bassetti M, Ansaldi F, De Florentiis D, Righi E, Pea F, Sartor A, Scarparo C, Carnelutti A.

Intensive Care Med. 2015 Nov;41(11):2026-8. doi: 10.1007/s00134-015-4021-9. Epub 2015 Aug 20. No abstract available.

PMID:
26289010
45.

Editorial overview: Anti-infectives: Current challenges and unmet needs in antimicrobial therapy.

Pea F.

Curr Opin Pharmacol. 2015 Oct;24:iv-vi. doi: 10.1016/j.coph.2015.08.001. Epub 2015 Aug 13. No abstract available.

PMID:
26278344
46.

Linezolid underexposure in a patient co-treated with venlafaxine.

Cojutti P, Crapis M, Bassetti M, Hope W, Pea F.

Eur J Clin Pharmacol. 2015 Oct;71(10):1285-6. doi: 10.1007/s00228-015-1922-z. Epub 2015 Aug 8. No abstract available.

PMID:
26253645
47.

Urological infections due to multidrug-resistant bacteria: what we need to know?

Cai T, De Nunzio C, Salonia A, Pea F, Mazzei T, Concia E, Battaglia M, Mirone V.

Urologia. 2016 Jan-Mar;83(1):21-6. doi: 10.5301/uro.5000123. Epub 2016 Feb 12. Review.

PMID:
26166012
48.

Antimicrobial treatment of bacterial infections in frail elderly patients: the difficult balance between efficacy, safety and tolerability.

Pea F.

Curr Opin Pharmacol. 2015 Oct;24:18-22. doi: 10.1016/j.coph.2015.06.006. Epub 2015 Jul 1. Review.

PMID:
26141569
49.

Pharmacokinetics and pharmacodynamics of continuous-infusion meropenem in pediatric hematopoietic stem cell transplant patients.

Cojutti P, Maximova N, Pea F.

Antimicrob Agents Chemother. 2015 Sep;59(9):5535-41. doi: 10.1128/AAC.00787-15. Epub 2015 Jun 29.

50.

Implementation of a Meningitis Care Bundle in the Emergency Room Reduces Mortality Associated With Acute Bacterial Meningitis.

Viale P, Scudeller L, Pea F, Tedeschi S, Lewis R, Bartoletti M, Sbrojavacca R, Cristini F, Tumietto F, Di Lauria N, Fasulo G, Giannella M.

Ann Pharmacother. 2015 Sep;49(9):978-85. doi: 10.1177/1060028015586012. Epub 2015 Jun 23.

PMID:
26104050

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