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Items: 33

1.

Correction: γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers.

Trošt N, Peña-Llopis S, Koirala S, Stojan J, Potts PR, Fon Tacer K, Martinez ED.

Oncotarget. 2019 Jan 25;10(8):916. doi: 10.18632/oncotarget.26649. eCollection 2019 Jan 25.

2.

Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability.

Tapia-Laliena MÁ, Korzeniewski N, Peña-Llopis S, Scholl C, Fröhling S, Hohenfellner M, Duensing A, Duensing S.

Oncogenesis. 2019 Jan 9;8(1):4. doi: 10.1038/s41389-018-0110-2.

3.

Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks.

Bayo J, Tran TA, Wang L, Peña-Llopis S, Das AK, Martinez ED.

Cell Rep. 2018 Oct 23;25(4):1040-1050.e5. doi: 10.1016/j.celrep.2018.09.081.

4.

Multistep regulation of TFEB by MTORC1.

Vega-Rubin-de-Celis S, Peña-Llopis S, Konda M, Brugarolas J.

Autophagy. 2017 Mar 4;13(3):464-472. doi: 10.1080/15548627.2016.1271514. Epub 2017 Jan 5.

5.

Unique epigenetic gene profiles define human breast cancers with poor prognosis.

Peña-Llopis S, Wan Y, Martinez ED.

Oncotarget. 2016 Dec 27;7(52):85819-85831. doi: 10.18632/oncotarget.13334.

6.

Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone.

Cheng WY, Huynh H, Chen P, Peña-Llopis S, Wan Y.

Elife. 2016 Oct 3;5. pii: e18501. doi: 10.7554/eLife.18501.

7.

Fibroblast Growth Factor Receptor-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant Renal Cell Carcinoma.

Tran TA, Leong HS, Pavia-Jimenez A, Fedyshyn S, Yang J, Kucejova B, Sivanand S, Spence P, Xie XJ, Peña-Llopis S, Power N, Brugarolas J.

Mol Cell Biol. 2016 Jun 15;36(13):1836-55. doi: 10.1128/MCB.00189-16. Print 2016 Jul 1.

8.

An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types.

Park S, Kim SJ, Yu D, Peña-Llopis S, Gao J, Park JS, Chen B, Norris J, Wang X, Chen M, Kim M, Yong J, Wardak Z, Choe K, Story M, Starr T, Cheong JH, Hwang TH.

Bioinformatics. 2016 Jun 1;32(11):1643-51. doi: 10.1093/bioinformatics/btv692. Epub 2015 Dec 3.

9.

γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers.

Trošt N, Peña-Llopis S, Koirala S, Stojan J, Potts PR, Fon Tacer K, Martinez ED.

Oncotarget. 2016 Jan 19;7(3):2611-28. doi: 10.18632/oncotarget.6006. Erratum in: Oncotarget. 2019 Jan 25;10(8):916.

10.

Prospective evaluation of plasma levels of ANGPT2, TuM2PK, and VEGF in patients with renal cell carcinoma.

Gayed BA, Gillen J, Christie A, Peña-Llopis S, Xie XJ, Yan J, Karam JA, Raj G, Sagalowsky AI, Lotan Y, Margulis V, Brugarolas J.

BMC Urol. 2015 Apr 3;15:24. doi: 10.1186/s12894-015-0019-4.

11.

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.

Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S.

Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17.

12.

N-Acetylcysteine boosts xenobiotic detoxification in shellfish.

Peña-Llopis S, Serrano R, Pitarch E, Beltrán E, Ibáñez M, Hernández F, Peña JB.

Aquat Toxicol. 2014 Sep;154:131-40. doi: 10.1016/j.aquatox.2014.05.006. Epub 2014 May 16.

PMID:
24880785
13.

Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.

Schuster K, Venkateswaran N, Rabellino A, Girard L, Peña-Llopis S, Scaglioni PP.

Mol Cancer Res. 2014 Jun;12(6):912-23. doi: 10.1158/1541-7786.MCR-13-0620-T. Epub 2014 Mar 11.

14.

Simultaneous isolation of high-quality DNA, RNA, miRNA and proteins from tissues for genomic applications.

Peña-Llopis S, Brugarolas J.

Nat Protoc. 2013 Nov;8(11):2240-55. doi: 10.1038/nprot.2013.141. Epub 2013 Oct 17.

15.

Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1.

Tran TA, Kinch L, Peña-Llopis S, Kockel L, Grishin N, Jiang H, Brugarolas J.

Mol Cell Biol. 2013 Oct;33(19):3762-79. doi: 10.1128/MCB.01570-12. Epub 2013 Jul 22.

16.

Cooperation and antagonism among cancer genes: the renal cancer paradigm.

Peña-Llopis S, Christie A, Xie XJ, Brugarolas J.

Cancer Res. 2013 Jul 15;73(14):4173-9. doi: 10.1158/0008-5472.CAN-13-0360. Epub 2013 Jul 5. Review.

17.

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth.

Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, Easmon J, Martinez ED.

Nat Commun. 2013;4:2035. doi: 10.1038/ncomms3035. Erratum in: Nat Commun. 2013;4:2639.

18.

A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma.

Farley MN, Schmidt LS, Mester JL, Pena-Llopis S, Pavia-Jimenez A, Christie A, Vocke CD, Ricketts CJ, Peterson J, Middelton L, Kinch L, Grishin N, Merino MJ, Metwalli AR, Xing C, Xie XJ, Dahia PLM, Eng C, Linehan WM, Brugarolas J.

Mol Cancer Res. 2013 Sep;11(9):1061-1071. doi: 10.1158/1541-7786.MCR-13-0111. Epub 2013 May 24.

19.

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation.

Kapur P, Peña-Llopis S, Christie A, Zhrebker L, Pavía-Jiménez A, Rathmell WK, Xie XJ, Brugarolas J.

Lancet Oncol. 2013 Feb;14(2):159-167. doi: 10.1016/S1470-2045(12)70584-3. Epub 2013 Jan 16.

20.

BAP1 loss defines a new class of renal cell carcinoma.

Peña-Llopis S, Vega-Rubín-de-Celis S, Liao A, Leng N, Pavía-Jiménez A, Wang S, Yamasaki T, Zhrebker L, Sivanand S, Spence P, Kinch L, Hambuch T, Jain S, Lotan Y, Margulis V, Sagalowsky AI, Summerour PB, Kabbani W, Wong SW, Grishin N, Laurent M, Xie XJ, Haudenschild CD, Ross MT, Bentley DR, Kapur P, Brugarolas J.

Nat Genet. 2012 Jun 10;44(7):751-9. doi: 10.1038/ng.2323. Erratum in: Nat Genet. 2012 Sep;44(9):1072.

21.

A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma.

Sivanand S, Peña-Llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jimenez A, Yamasaki T, McBride DJ, Gillen J, Wolff NC, Morlock L, Lotan Y, Raj GV, Sagalowsky A, Margulis V, Cadeddu JA, Ross MT, Bentley DR, Kabbani W, Xie XJ, Kapur P, Williams NS, Brugarolas J.

Sci Transl Med. 2012 Jun 6;4(137):137ra75. doi: 10.1126/scitranslmed.3003643.

22.

TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy.

Peña-Llopis S, Brugarolas J.

Cell Cycle. 2011 Dec 1;10(23):3987-8. doi: 10.4161/cc.10.23.18251. Epub 2011 Dec 1. No abstract available.

23.

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.

Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM.

Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645.

24.

Regulation of TFEB and V-ATPases by mTORC1.

Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J.

EMBO J. 2011 Jul 29;30(16):3242-58. doi: 10.1038/emboj.2011.257.

25.

Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.

Kucejova B, Peña-Llopis S, Yamasaki T, Sivanand S, Tran TA, Alexander S, Wolff NC, Lotan Y, Xie XJ, Kabbani W, Kapur P, Brugarolas J.

Mol Cancer Res. 2011 Sep;9(9):1255-65. doi: 10.1158/1541-7786.MCR-11-0302. Epub 2011 Jul 28.

26.

Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death.

Kucejova B, Sunny NE, Nguyen AD, Hallac R, Fu X, Peña-Llopis S, Mason RP, Deberardinis RJ, Xie XJ, Debose-Boyd R, Kodibagkar VD, Burgess SC, Brugarolas J.

Oncogene. 2011 May 5;30(18):2147-60. doi: 10.1038/onc.2010.587. Epub 2011 Jan 10.

27.

Regulation of superoxide stress in Pseudomonas putida KT2440 is different from the SoxR paradigm in Escherichia coli.

Park W, Peña-Llopis S, Lee Y, Demple B.

Biochem Biophys Res Commun. 2006 Mar 3;341(1):51-6. Epub 2006 Jan 6.

PMID:
16412384
28.

Expression analysis of the fpr (ferredoxin-NADP+ reductase) gene in Pseudomonas putida KT2440.

Lee Y, Peña-Llopis S, Kang YS, Shin HD, Demple B, Madsen EL, Jeon CO, Park W.

Biochem Biophys Res Commun. 2006 Jan 27;339(4):1246-54.

PMID:
16360643
29.

Constitutive soxR mutations contribute to multiple-antibiotic resistance in clinical Escherichia coli isolates.

Koutsolioutsou A, Peña-Llopis S, Demple B.

Antimicrob Agents Chemother. 2005 Jul;49(7):2746-52.

30.
32.
33.

Glutathione-dependent resistance of the European eel Anguilla anguilla to the herbicide molinate.

Peña-Llopis S, Peña JB, Sancho E, Fernández-Vega C, Ferrando MD.

Chemosphere. 2001 Nov;45(4-5):671-81.

PMID:
11680763

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