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Items: 43

1.

Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy.

Weichert JP, Clark PA, Kandela IK, Vaccaro AM, Clarke W, Longino MA, Pinchuk AN, Farhoud M, Swanson KI, Floberg JM, Grudzinski J, Titz B, Traynor AM, Chen HE, Hall LT, Pazoles CJ, Pickhardt PJ, Kuo JS.

Sci Transl Med. 2014 Jun 11;6(240):240ra75. doi: 10.1126/scitranslmed.3007646.

2.

NOV-002, A Glutathione Disulfide Mimetic, Suppresses Tumor Cell Invasion and Metastasis.

Gumireddy K, Li A, Cao L, Yan J, Liu L, Xu X, Pazoles C, Huang Q.

J Carcinog Mutagen. 2013 Apr 30;2013. pii: S7-002.

3.

S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs.

Grek CL, Townsend DM, Uys JD, Manevich Y, Coker WJ 3rd, Pazoles CJ, Tew KD.

Cancer Res. 2012 May 1;72(9):2383-93. doi: 10.1158/0008-5472.CAN-11-4088. Epub 2012 Mar 8.

4.

The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress.

Diaz-Montero CM, Wang Y, Shao L, Feng W, Zidan AA, Pazoles CJ, Montero AJ, Zhou D.

Free Radic Biol Med. 2012 May 1;52(9):1560-8. doi: 10.1016/j.freeradbiomed.2012.02.007. Epub 2012 Feb 15.

5.

Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic.

Uys JD, Manevich Y, Devane LC, He L, Garret TE, Pazoles CJ, Tew KD, Townsend DM.

Biomed Pharmacother. 2010 Sep;64(7):493-8. doi: 10.1016/j.biopha.2010.01.003. Epub 2010 Feb 24.

6.

Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress.

Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD.

J Biol Chem. 2009 Jan 2;284(1):436-45. doi: 10.1074/jbc.M805586200. Epub 2008 Nov 6.

7.

NOV-002, a mimetic of glutathione disulfide.

Townsend DM, Pazoles CJ, Tew KD.

Expert Opin Investig Drugs. 2008 Jul;17(7):1075-83. doi: 10.1517/13543784.17.7.1075 .

PMID:
18549343
8.

NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance.

Townsend DM, He L, Hutchens S, Garrett TE, Pazoles CJ, Tew KD.

Cancer Res. 2008 Apr 15;68(8):2870-7. doi: 10.1158/0008-5472.CAN-07-5957.

9.

Enterococcus faecalis multi-drug resistance transporters: application for antibiotic discovery.

Davis DR, McAlpine JB, Pazoles CJ, Talbot MK, Alder EA, White C, Jonas BM, Murray BE, Weinstock GM, Rogers BL.

J Mol Microbiol Biotechnol. 2001 Apr;3(2):179-84. Review.

PMID:
11321571
10.

The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-alpha (TNFalpha) production in mice: effect of adrenalectomy.

Cheng JB, Watson JW, Pazoles CJ, Eskra JD, Griffiths RJ, Cohan VL, Turner CR, Showell HJ, Pettipher ER.

J Pharmacol Exp Ther. 1997 Feb;280(2):621-6.

11.

In vitro pharmacology of the novel phosphodiesterase type 4 inhibitor, CP-80633.

Cohan VL, Showell HJ, Fisher DA, Pazoles CJ, Watson JW, Turner CR, Cheng JB.

J Pharmacol Exp Ther. 1996 Sep;278(3):1356-61.

PMID:
8819523
12.

The in vivo pharmacology of CP-80, 633, a selective inhibitor of phosphodiesterase 4.

Turner CR, Cohan VL, Cheng JB, Showell HJ, Pazoles CJ, Watson JW.

J Pharmacol Exp Ther. 1996 Sep;278(3):1349-55.

PMID:
8819522
13.

Inhibition of cytokine activation processes in vitro by tenidap, a novel anti-inflammatory agent.

McNiff PA, Laliberte RE, Svensson L, Pazoles CJ, Gabel CA.

Cytokine. 1995 Feb;7(2):196-208.

PMID:
7780040
14.

Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. I. Mechanism and evidence of functional significance.

McNiff P, Svensson L, Pazoles CJ, Gabel CA.

J Immunol. 1994 Sep 1;153(5):2180-93.

PMID:
8051419
15.
16.

Potentiation of morphine antinociception by monoamine reuptake inhibitors in the rat spinal cord.

Taiwo YO, Fabian A, Pazoles CJ, Fields HL.

Pain. 1985 Apr;21(4):329-37.

PMID:
4000684
17.

A role for bombesin in sensory processing in the spinal cord.

O'Donohue TL, Massari VJ, Pazoles CJ, Chronwall BM, Shults CW, Quirion R, Chase TN, Moody TW.

J Neurosci. 1984 Dec;4(12):2956-62.

18.

An osmotic mechanism for exocytosis from dissociated chromaffin cells.

Pollard HB, Pazoles CJ, Creutz CE, Scott JH, Zinder O, Hotchkiss A.

J Biol Chem. 1984 Jan 25;259(2):1114-21.

19.

Anion and proton transport in chromaffin granules.

Pazoles CJ.

Fed Proc. 1982 Sep;41(11):2769-74.

PMID:
6288478
20.

Calcium-dependent regulation of chromaffin granule movement, membrane contact, and fusion during exocytosis.

Pollard HB, Creutz CE, Fowler V, Scott J, Pazoles CJ.

Cold Spring Harb Symp Quant Biol. 1982;46 Pt 2:819-34. Review. No abstract available.

PMID:
6213354
21.
22.
23.

A simple and novel method for radiometric analysis of glucose utilization by adrenal chromaffin cells.

Pollard HB, Stopak SS, Pazoles CJ, Creutz CE.

Anal Biochem. 1981 Jan 15;110(2):424-30. No abstract available.

PMID:
7235229
24.

Role of Ions and intracellular proteins in exocytosis.

Pollard HB, Creutz CE, Pazoles CJ.

Methods Cell Biol. 1981;23:313-34. No abstract available.

PMID:
6460150
25.

Mechanism of calcium action and release of vesicle-bound hormones during exocytosis.

Pollard HB, Pazoles CJ, Creutz CE.

Recent Prog Horm Res. 1981;37:299-332. No abstract available.

PMID:
6456530
26.

Permeant anion activation of MgATPase activity in chromaffin granules. Evidence for direct coupling of proton and anion transport.

Pazoles CJ, Creutz CE, Ramu A, Pollard HB.

J Biol Chem. 1980 Aug 25;255(16):7863-9. No abstract available.

27.

Identification and subcellular localization of catalase activity in bovine adrenal medulla and cortex.

Pazoles CJ, Claggett CE, Creutz CE, Pollard HB, Weinbach EC.

Arch Biochem Biophys. 1980 Apr 1;200(2):434-43. No abstract available.

PMID:
7436413
28.

Evidence for direct coupling of proton and anion transport in chromaffin granules.

Pazoles CJ, Creutz CE, Pollard HB.

Ann N Y Acad Sci. 1980;358:354-5. No abstract available.

PMID:
6259998
29.

Role of intracellular proteins in the regulation of calcium action and transmitter release during exocytosis.

Pollard HB, Pazoles CJ, Creutz CE, Zinder O.

Monogr Neural Sci. 1980;7:106-16.

PMID:
6112701
30.

A simplified, one-step method for radiometric analysis of phenylethanolamine-N-methyltransferase in adrenal chromaffin cells.

Pollard HB, Stopak SS, Pazoles CJ, Creutz CE.

Anal Biochem. 1979 Nov 1;99(2):281-2. No abstract available.

PMID:
517741
31.

Internal pH and state of ATP in adrenergic chromaffin granules determined by 31P nuclear magnetic resonance spectroscopy.

Pollard HB, Shindo H, Creutz CE, Pazoles CJ, Cohen JS.

J Biol Chem. 1979 Feb 25;254(4):1170-7. No abstract available.

33.

The chromaffin granule and possible mechanisms of exocytosis.

Pollard HB, Pazoles CJ, Creutz CE, Zinder O.

Int Rev Cytol. 1979;58:159-97. Review. No abstract available.

PMID:
391762
34.

Evidence for stimulation of anion transport in ATP-evoked transmitter release from isolated secretory vesicles.

Pazoles CJ, Pollard HB.

J Biol Chem. 1978 Jun 10;253(11):3962-9. No abstract available.

35.

Application of Bradford's protein assay to adrenal gland subcellular fractions.

Pollard HB, Menard R, Brandt HA, Pazoles CJ, Creutz CE, Ramu A.

Anal Biochem. 1978 Jun 1;86(2):761-3. No abstract available.

PMID:
77646
36.
37.

Role of anions in parathyroid hormone release from dispersed bovine parathyroid cells.

Brown EM, Pazoles CJ, Creutz CE, Aurbach GD, Pollard HB.

Proc Natl Acad Sci U S A. 1978 Feb;75(2):876-80.

38.

Evidence for control of serotonin secretion from human platelets by hydroxyl ion transport and osmotic lysis.

Pollard HB, Tack-Goldman K, Pazoles CJ, Creutz CE, Shulman NR.

Proc Natl Acad Sci U S A. 1977 Dec;74(12):5295-9.

39.

Calcium binding properties of monovalent anions commonly used to substitute for chloride in physiological salt solutions.

Pollard HB, Ceutz CE, Pazoles CJ, Hansen J.

Anal Biochem. 1977 Nov;83(1):311-4. No abstract available.

PMID:
920948
40.

Biosynthesis and structure of lipopolysaccharide in an outer membrane-defective mutant of Escherichia coli J5.

Pazoles CJ, Kulpa CF Jr.

Biochim Biophys Acta. 1977 Apr 1;466(1):160-75.

PMID:
322711
41.

A role for anion transport in the regulation of release from chromaffin granules and exocytosis from cells.

Pollard HB, Pazoles CJ, Creutz CE, Ramu A, Strott CA, Ray P, Brown EM, Aurbach GD, Tack-Goldman KM, Shulman NR.

J Supramol Struct. 1977;7(3-4):277-85. No abstract available.

PMID:
616482
42.

Regulation of release from isolated adrenergic secretory vesicles by ATP-mediated changes in transmembrane potential and anion permeability.

Pollard HB, Pazoles CJ, Hoffman PG, Zinder O, Nikodijevik O.

Prog Clin Biol Res. 1977;15:259-66.

PMID:
22084
43.

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