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Items: 1 to 50 of 119

1.

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.

Veeraragavan S, Wan YW, Connolly DR, Hamilton SM, Ward CS, Soriano S, Pitcher MR, McGraw CM, Huang SG, Green JR, Yuva LA, Liang AJ, Neul JL, Yasui DH, LaSalle JM, Liu Z, Paylor R, Samaco RC.

Hum Mol Genet. 2016 Aug 1;25(15):3284-3302. doi: 10.1093/hmg/ddw178. Epub 2016 Jun 30.

2.

Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.

Guo W, Molinaro G, Collins KA, Hays SA, Paylor R, Worley PF, Szumlinski KK, Huber KM.

J Neurosci. 2016 Feb 17;36(7):2131-47. doi: 10.1523/JNEUROSCI.2921-15.2016.

3.

Applying the ARRIVE Guidelines to an In Vivo Database.

Karp NA, Meehan TF, Morgan H, Mason JC, Blake A, Kurbatova N, Smedley D, Jacobsen J, Mott RF, Iyer V, Matthews P, Melvin DG, Wells S, Flenniken AM, Masuya H, Wakana S, White JK, Lloyd KC, Reynolds CL, Paylor R, West DB, Svenson KL, Chesler EJ, de Angelis MH, Tocchini-Valentini GP, Sorg T, Herault Y, Parkinson H, Mallon AM, Brown SD.

PLoS Biol. 2015 May 20;13(5):e1002151. doi: 10.1371/journal.pbio.1002151. eCollection 2015 May.

4.

Fmr1 and Nlgn3 knockout rats: novel tools for investigating autism spectrum disorders.

Hamilton SM, Green JR, Veeraragavan S, Yuva L, McCoy A, Wu Y, Warren J, Little L, Ji D, Cui X, Weinstein E, Paylor R.

Behav Neurosci. 2014 Apr;128(2):103-9. doi: 10.1037/a0035988.

PMID:
24773431
5.

Deficits in adult neurogenesis, contextual fear conditioning, and spatial learning in a Gfap mutant mouse model of Alexander disease.

Hagemann TL, Paylor R, Messing A.

J Neurosci. 2013 Nov 20;33(47):18698-706. doi: 10.1523/JNEUROSCI.3693-13.2013.

6.

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

Henderson C, Wijetunge L, Kinoshita MN, Shumway M, Hammond RS, Postma FR, Brynczka C, Rush R, Thomas A, Paylor R, Warren ST, Vanderklish PW, Kind PC, Carpenter RL, Bear MF, Healy AM.

Sci Transl Med. 2012 Sep 19;4(152):152ra128.

7.

Enriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits.

Lacaria M, Spencer C, Gu W, Paylor R, Lupski JR.

Hum Mol Genet. 2012 Jul 15;21(14):3083-96. doi: 10.1093/hmg/dds124. Epub 2012 Apr 5.

8.

Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse.

Cowin RM, Roscic A, Bui N, Graham D, Paganetti P, Jankowsky JL, Weiss A, Paylor R.

Behav Brain Res. 2012 Apr 15;229(2):308-19. doi: 10.1016/j.bbr.2011.12.045. Epub 2012 Jan 28.

PMID:
22306231
9.

Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis.

Cowin RM, Bui N, Graham D, Green JR, Yuva-Paylor LA, Weiss A, Paylor R.

Mamm Genome. 2012 Jun;23(5-6):367-77. doi: 10.1007/s00335-012-9391-5.

10.

Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability.

Cowin RM, Bui N, Graham D, Green JR, Grueninger S, Yuva-Paylor LA, Syed AU, Weiss A, Paylor R.

PLoS One. 2011;6(12):e28409. doi: 10.1371/journal.pone.0028409. Epub 2011 Dec 7.

11.

Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS).

Veeraragavan S, Graham D, Bui N, Yuva-Paylor LA, Wess J, Paylor R.

Behav Brain Res. 2012 Mar 1;228(1):1-8. doi: 10.1016/j.bbr.2011.11.018. Epub 2011 Nov 23.

12.

The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide.

Veeraragavan S, Bui N, Perkins JR, Yuva-Paylor LA, Paylor R.

Behav Neurosci. 2011 Oct;125(5):783-90. doi: 10.1037/a0025202.

13.

Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome.

Thomas AM, Bui N, Perkins JR, Yuva-Paylor LA, Paylor R.

Psychopharmacology (Berl). 2012 Jan;219(1):47-58. doi: 10.1007/s00213-011-2375-4. Epub 2011 Jun 10.

PMID:
21656124
14.

Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.

Thomas AM, Bui N, Graham D, Perkins JR, Yuva-Paylor LA, Paylor R.

Behav Brain Res. 2011 Oct 1;223(2):310-21. doi: 10.1016/j.bbr.2011.04.049. Epub 2011 May 6.

15.

R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI.

Smith KD, Paylor R, Pautler RG.

Magn Reson Med. 2011 May;65(5):1423-9. doi: 10.1002/mrm.22733. Epub 2010 Dec 8.

16.

Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome.

Veeraragavan S, Bui N, Perkins JR, Yuva-Paylor LA, Carpenter RL, Paylor R.

Psychopharmacology (Berl). 2011 Sep;217(1):143-51. doi: 10.1007/s00213-011-2276-6. Epub 2011 Apr 13.

PMID:
21487657
17.

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.

Spencer CM, Alekseyenko O, Hamilton SM, Thomas AM, Serysheva E, Yuva-Paylor LA, Paylor R.

Autism Res. 2011 Feb;4(1):40-56. doi: 10.1002/aur.168. Epub 2011 Jan 25.

18.

Multiple autism-like behaviors in a novel transgenic mouse model.

Hamilton SM, Spencer CM, Harrison WR, Yuva-Paylor LA, Graham DF, Daza RA, Hevner RF, Overbeek PA, Paylor R.

Behav Brain Res. 2011 Mar 17;218(1):29-41. doi: 10.1016/j.bbr.2010.11.026. Epub 2010 Nov 17.

19.

Histone methylation regulates memory formation.

Gupta S, Kim SY, Artis S, Molfese DL, Schumacher A, Sweatt JD, Paylor RE, Lubin FD.

J Neurosci. 2010 Mar 10;30(10):3589-99. doi: 10.1523/JNEUROSCI.3732-09.2010.

20.

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.

Li HH, Roy M, Kuscuoglu U, Spencer CM, Halm B, Harrison KC, Bayle JH, Splendore A, Ding F, Meltzer LA, Wright E, Paylor R, Deisseroth K, Francke U.

EMBO Mol Med. 2009 Apr;1(1):50-65. doi: 10.1002/emmm.200900003.

21.

A mouse model of the human Fragile X syndrome I304N mutation.

Zang JB, Nosyreva ED, Spencer CM, Volk LJ, Musunuru K, Zhong R, Stone EF, Yuva-Paylor LA, Huber KM, Paylor R, Darnell JC, Darnell RB.

PLoS Genet. 2009 Dec;5(12):e1000758. doi: 10.1371/journal.pgen.1000758. Epub 2009 Dec 11.

22.

Early changes in the apparent diffusion coefficient (ADC) in a mouse model of Sandhoff's disease occur prior to disease symptoms and behavioral deficits.

Hu L, Sun Y, Villasana LE, Paylor R, Klann E, Pautler RG.

Magn Reson Med. 2009 Nov;62(5):1175-84. doi: 10.1002/mrm.22138.

23.

Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging.

McKinney AM, Kieffer SA, Paylor RT, SantaCruz KS, Kendi A, Lucato L.

AJR Am J Roentgenol. 2009 Jul;193(1):192-206. doi: 10.2214/AJR.08.1176.

PMID:
19542414
24.

Ectopic expression of CGG containing mRNA is neurotoxic in mammals.

Hashem V, Galloway JN, Mori M, Willemsen R, Oostra BA, Paylor R, Nelson DL.

Hum Mol Genet. 2009 Jul 1;18(13):2443-51. doi: 10.1093/hmg/ddp182. Epub 2009 Apr 18.

25.

Questioning standardization in science.

Paylor R.

Nat Methods. 2009 Apr;6(4):253-4. doi: 10.1038/nmeth0409-253. No abstract available.

PMID:
19333239
26.

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety.

Thomas A, Burant A, Bui N, Graham D, Yuva-Paylor LA, Paylor R.

Psychopharmacology (Berl). 2009 Jun;204(2):361-73. doi: 10.1007/s00213-009-1466-y. Epub 2009 Feb 3.

27.

Simultaneous behavioral characterizations: Embracing complexity.

Paylor R.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20563-4. doi: 10.1073/pnas.0811546106. Epub 2008 Dec 23. No abstract available.

28.

Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior.

Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E.

Neuron. 2008 Dec 10;60(5):832-45. doi: 10.1016/j.neuron.2008.09.037.

29.

Reversal of sensorimotor gating abnormalities in Fmr1 knockout mice carrying a human Fmr1 transgene.

Paylor R, Yuva-Paylor LA, Nelson DL, Spencer CM.

Behav Neurosci. 2008 Dec;122(6):1371-7. doi: 10.1037/a0013047.

PMID:
19045956
30.

Pitfalls in the interpretation of genetic and pharmacological effects on anxiety-like behaviour in rodents.

Bouwknecht JA, Paylor R.

Behav Pharmacol. 2008 Sep;19(5-6):385-402. doi: 10.1097/FBP.0b013e32830c3658. Review.

PMID:
18690100
31.

Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene.

Spencer CM, Graham DF, Yuva-Paylor LA, Nelson DL, Paylor R.

Behav Neurosci. 2008 Jun;122(3):710-5. doi: 10.1037/0735-7044.122.3.710.

PMID:
18513141
32.

Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes.

Bi W, Yan J, Shi X, Yuva-Paylor LA, Antalffy BA, Goldman A, Yoo JW, Noebels JL, Armstrong DL, Paylor R, Lupski JR.

Hum Mol Genet. 2007 Aug 1;16(15):1802-13. Epub 2007 May 21.

PMID:
17517686
33.

Rai1 duplication causes physical and behavioral phenotypes in a mouse model of dup(17)(p11.2p11.2).

Walz K, Paylor R, Yan J, Bi W, Lupski JR.

J Clin Invest. 2006 Nov;116(11):3035-41. Epub 2006 Oct 5.

34.

Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior.

Nishijima I, Yamagata T, Spencer CM, Weeber EJ, Alekseyenko O, Sweatt JD, Momoi MY, Ito M, Armstrong DL, Nelson DL, Paylor R, Bradley A.

Hum Mol Genet. 2006 Nov 1;15(21):3241-50. Epub 2006 Sep 28.

35.

Fmr1 knockout mice are impaired in a leverpress escape/avoidance task.

Brennan FX, Albeck DS, Paylor R.

Genes Brain Behav. 2006 Aug;5(6):467-71.

36.
37.

Phenotypic characterization of Bbs4 null mice reveals age-dependent penetrance and variable expressivity.

Eichers ER, Abd-El-Barr MM, Paylor R, Lewis RA, Bi W, Lin X, Meehan TP, Stockton DW, Wu SM, Lindsay E, Justice MJ, Beales PL, Katsanis N, Lupski JR.

Hum Genet. 2006 Sep;120(2):211-26. Epub 2006 Jun 23.

PMID:
16794820
38.

Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.

Paylor R, Glaser B, Mupo A, Ataliotis P, Spencer C, Sobotka A, Sparks C, Choi CH, Oghalai J, Curran S, Murphy KC, Monks S, Williams N, O'Donovan MC, Owen MJ, Scambler PJ, Lindsay E.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7729-34. Epub 2006 May 9.

39.

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

Spencer CM, Serysheva E, Yuva-Paylor LA, Oostra BA, Nelson DL, Paylor R.

Hum Mol Genet. 2006 Jun 15;15(12):1984-94. Epub 2006 May 4.

PMID:
16675531
40.

The stress-induced hyperthermia paradigm as a physiological animal model for anxiety: a review of pharmacological and genetic studies in the mouse.

Adriaan Bouwknecht J, Olivier B, Paylor RE.

Neurosci Biobehav Rev. 2007;31(1):41-59. Epub 2006 Apr 17. Review.

PMID:
16618509
41.

Mouse models of 22q11 deletion syndrome.

Paylor R, Lindsay E.

Biol Psychiatry. 2006 Jun 15;59(12):1172-9. Epub 2006 Apr 17. Review.

PMID:
16616724
42.

Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function.

Davis RJ, Pesah YI, Harding M, Paylor R, Mardon G.

Genesis. 2006 Feb;44(2):84-92.

PMID:
16470613
43.

The use of behavioral test batteries, II: effect of test interval.

Paylor R, Spencer CM, Yuva-Paylor LA, Pieke-Dahl S.

Physiol Behav. 2006 Jan 30;87(1):95-102. Epub 2005 Sep 28.

PMID:
16197969
44.

Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome.

Spencer CM, Alekseyenko O, Serysheva E, Yuva-Paylor LA, Paylor R.

Genes Brain Behav. 2005 Oct;4(7):420-30.

45.

Deletion of the beta 2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation.

McCallum SE, Collins AC, Paylor R, Marks MJ.

Psychopharmacology (Berl). 2006 Mar;184(3-4):314-27. Epub 2005 Jul 2.

PMID:
16001112
46.

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

Bowers BJ, McClure-Begley TD, Keller JJ, Paylor R, Collins AC, Wehner JM.

Alcohol Clin Exp Res. 2005 Mar;29(3):295-302.

PMID:
15770102
47.

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

Moretti P, Bouwknecht JA, Teague R, Paylor R, Zoghbi HY.

Hum Mol Genet. 2005 Jan 15;14(2):205-20. Epub 2004 Nov 17.

PMID:
15548546
48.
49.

Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning.

Wehner JM, Keller JJ, Keller AB, Picciotto MR, Paylor R, Booker TK, Beaudet A, Heinemann SF, Balogh SA.

Neuroscience. 2004;129(1):11-24.

PMID:
15489024
50.

Behavioral and physiological mouse models for anxiety: effects of flesinoxan in 129S6/SvEvTac and C57BL/6J mice.

Bouwknecht JA, van der Gugten J, Groenink L, Olivier B, Paylor RE.

Eur J Pharmacol. 2004 Jun 21;494(1):45-53.

PMID:
15194450

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