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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 3
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1994 17
1995 21
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1997 33
1998 39
1999 53
2000 51
2001 51
2002 66
2003 56
2004 38
2005 59
2006 78
2007 63
2008 74
2009 85
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1,796 results

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Page 1
The Role of PAX2 in Neurodevelopment and Disease.
Lv N, Wang Y, Zhao M, Dong L, Wei H. Lv N, et al. Neuropsychiatr Dis Treat. 2021 Dec 7;17:3559-3567. doi: 10.2147/NDT.S332747. eCollection 2021. Neuropsychiatr Dis Treat. 2021. PMID: 34908837 Free PMC article. Review.
Secondly, the structure of Pax2 gene and PAX2 protein, as well as the function of Pax2 gene in neural development, was discussed. Finally, a diagram of the PAX2 protein regulatory network was made and a possible molecular mechanism of Pax2 mutat …
Secondly, the structure of Pax2 gene and PAX2 protein, as well as the function of Pax2 gene in neural development, was …
PAX2-Related Disorder.
Bower MA, Schimmenti LA, Eccles MR. Bower MA, et al. 2007 Jun 8 [updated 2018 Feb 8]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2007 Jun 8 [updated 2018 Feb 8]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301624 Free Books & Documents. Review.
DIAGNOSIS/TESTING: The diagnosis of PAX2-related disorder is established in a proband with the characteristic renal and/or eye findings by the identification of a heterozygous pathogenic variant in PAX2 by molecular genetic testing. ...GENETIC COUNSELING: PAX2 …
DIAGNOSIS/TESTING: The diagnosis of PAX2-related disorder is established in a proband with the characteristic renal and/or eye findin …
PAX2 Gene Mutation in Pediatric Renal Disorders-A Narrative Review.
Muntean C, Chirtes C, Baczoni B, Banescu C. Muntean C, et al. Int J Mol Sci. 2023 Aug 13;24(16):12737. doi: 10.3390/ijms241612737. Int J Mol Sci. 2023. PMID: 37628926 Free PMC article. Review.
The PAX2 gene is a transcription factor that is essential for the development of the urinary system among other transcription factors. The role of PAX2 is highlighted from the seventh week of gestation, when it is involved in development processes and the emergence …
The PAX2 gene is a transcription factor that is essential for the development of the urinary system among other transcription factors …
Reliable Identification of Endometrial Precancers Through Combined Pax2, beta-Catenin, and Pten Immunohistochemistry.
Aguilar M, Chen H, Rivera-Colon G, Niu S, Carrick K, Gwin K, Cuevas IC, Sahoo SS, Li HD, Zhang S, Zheng W, Lucas E, Castrillon DH. Aguilar M, et al. Am J Surg Pathol. 2022 Mar 1;46(3):404-414. doi: 10.1097/PAS.0000000000001810. Am J Surg Pathol. 2022. PMID: 34545858 Free PMC article.
For example, the World Health Organization 2020 Classification specifies that loss of Pten, Pax2, or mismatch repair proteins are desirable diagnostic criteria. ...Arid1a, Mlh1, and p53 were robust and readily scored markers, but all cases showing aberrant expression of th …
For example, the World Health Organization 2020 Classification specifies that loss of Pten, Pax2, or mismatch repair proteins are des …
Pax2 in development and renal disease.
Dressler GR, Woolf AS. Dressler GR, et al. Int J Dev Biol. 1999;43(5):463-8. Int J Dev Biol. 1999. PMID: 10535325 Review.
However, Pax2 expression is down-regulated as cells leave the mitotic cycle. Humans carrying a single Pax2 mutant allele exhibit renal hypoplasia, vesicoureteric reflux, and optic nerve colobomas. ...
However, Pax2 expression is down-regulated as cells leave the mitotic cycle. Humans carrying a single Pax2 mutant allele exhib …
PAX2 in human kidney malformations and disease.
Harshman LA, Brophy PD. Harshman LA, et al. Pediatr Nephrol. 2012 Aug;27(8):1265-75. doi: 10.1007/s00467-011-2053-0. Epub 2011 Dec 3. Pediatr Nephrol. 2012. PMID: 22138676 Review.
Defining the relationship of PAX2 to human renal disease requires an appreciation of its fundamental role in renal development. Given the highly conserved nature of the PAX2 gene in vertebrates, it is not surprising that much of our understanding of PAX2 invo …
Defining the relationship of PAX2 to human renal disease requires an appreciation of its fundamental role in renal development. Given …
PAX2 induces vascular-like structures in normal ovarian cells and ovarian cancer.
Alwosaibai K, Al-Hujaily EM, Alamri S, Ghandorah S, Garson K, Vanderhyden BC. Alwosaibai K, et al. Exp Ther Med. 2022 Jun;23(6):412. doi: 10.3892/etm.2022.11339. Epub 2022 Apr 27. Exp Ther Med. 2022. PMID: 35601066 Free PMC article.
In adult tissue, the paired box 2 (PAX2) protein is expressed in healthy oviductal, but not normal ovarian surface epithelial cells. PAX2 is expressed in a subset of cases of serous ovarian carcinoma; however, the role of PAX2 in the initiation and progressio …
In adult tissue, the paired box 2 (PAX2) protein is expressed in healthy oviductal, but not normal ovarian surface epithelial cells. …
UnPAXing the Divergent Roles of PAX2 and PAX8 in High-Grade Serous Ovarian Cancer.
Hardy LR, Salvi A, Burdette JE. Hardy LR, et al. Cancers (Basel). 2018 Aug 8;10(8):262. doi: 10.3390/cancers10080262. Cancers (Basel). 2018. PMID: 30096791 Free PMC article. Review.
PAX2 expression is lost early in serous cancer progression, while PAX8 is expressed ubiquitously. ...In this review, we examine the implications of PAX2 and PAX8 expression in the cell of origin of serous cancer and their potential efficacy as drug targets by summar …
PAX2 expression is lost early in serous cancer progression, while PAX8 is expressed ubiquitously. ...In this review, we examine the i …
New PAX2 heterozygous mutation in a child with chronic kidney disease: a case report and review of the literature.
Zhang L, Zhai SB, Zhao LY, Zhang Y, Sun BC, Ma QS. Zhang L, et al. BMC Nephrol. 2018 Sep 21;19(1):245. doi: 10.1186/s12882-018-1044-9. BMC Nephrol. 2018. PMID: 30241513 Free PMC article. Review.
BACKGROUND: We herein report a 3-year-old boy presented with chronic kidney disease (CKD) due to PAX2 missense mutation (C to G transversion at position 418 in exon 4). ...Genetic investigations revealed that he has inherited a mutated PAX2 gene from his father, who …
BACKGROUND: We herein report a 3-year-old boy presented with chronic kidney disease (CKD) due to PAX2 missense mutation (C to G trans …
Renal hypoplasia: lessons from Pax2.
Dziarmaga A, Quinlan J, Goodyer P. Dziarmaga A, et al. Pediatr Nephrol. 2006 Jan;21(1):26-31. doi: 10.1007/s00467-005-2039-x. Epub 2005 Nov 5. Pediatr Nephrol. 2006. PMID: 16273412 Review.
In this review, we use lessons from the study of Pax2 as organizing principles to focus on the developmental processes which, if disrupted, might lead to renal hypoplasia in humans. ...Finally, the effect of Pax2 on apoptosis in the branching ureteric bud seems to i …
In this review, we use lessons from the study of Pax2 as organizing principles to focus on the developmental processes which, if disr …
1,796 results