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Items: 8

1.

Trichlorination of a Teicoplanin-Type Glycopeptide Antibiotic by the Halogenase StaI Evades Resistance.

Yim G, Wang W, Pawlowski AC, Wright GD.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01540-18. doi: 10.1128/AAC.01540-18. Print 2018 Dec.

PMID:
30275088
2.

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.

Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD.

Nat Commun. 2018 Jan 9;9(1):112. doi: 10.1038/s41467-017-02680-0.

3.

The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies.

Pawlowski AC, Westman EL, Koteva K, Waglechner N, Wright GD.

ISME J. 2018 Mar;12(3):885-897. doi: 10.1038/s41396-017-0017-5. Epub 2017 Dec 19.

PMID:
29259290
4.

A Common Platform for Antibiotic Dereplication and Adjuvant Discovery.

Cox G, Sieron A, King AM, De Pascale G, Pawlowski AC, Koteva K, Wright GD.

Cell Chem Biol. 2017 Jan 19;24(1):98-109. doi: 10.1016/j.chembiol.2016.11.011. Epub 2016 Dec 22.

5.

A diverse intrinsic antibiotic resistome from a cave bacterium.

Pawlowski AC, Wang W, Koteva K, Barton HA, McArthur AG, Wright GD.

Nat Commun. 2016 Dec 8;7:13803. doi: 10.1038/ncomms13803.

6.

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database.

Jia B, Raphenya AR, Alcock B, Waglechner N, Guo P, Tsang KK, Lago BA, Dave BM, Pereira S, Sharma AN, Doshi S, Courtot M, Lo R, Williams LE, Frye JG, Elsayegh T, Sardar D, Westman EL, Pawlowski AC, Johnson TA, Brinkman FS, Wright GD, McArthur AG.

Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. doi: 10.1093/nar/gkw1004. Epub 2016 Oct 26.

7.

Evolving medicinal chemistry strategies in antibiotic discovery.

Pawlowski AC, Johnson JW, Wright GD.

Curr Opin Biotechnol. 2016 Dec;42:108-117. doi: 10.1016/j.copbio.2016.04.006. Epub 2016 Apr 24. Review.

PMID:
27116217
8.

The comprehensive antibiotic resistance database.

McArthur AG, Waglechner N, Nizam F, Yan A, Azad MA, Baylay AJ, Bhullar K, Canova MJ, De Pascale G, Ejim L, Kalan L, King AM, Koteva K, Morar M, Mulvey MR, O'Brien JS, Pawlowski AC, Piddock LJ, Spanogiannopoulos P, Sutherland AD, Tang I, Taylor PL, Thaker M, Wang W, Yan M, Yu T, Wright GD.

Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57. doi: 10.1128/AAC.00419-13. Epub 2013 May 6.

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