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Items: 8


Soluble CD93 is an apoptotic cell opsonin recognized by αx β2.

Blackburn JWD, Lau DHC, Liu EY, Ellins J, Vrieze AM, Pawlak EN, Dikeakos JD, Heit B.

Eur J Immunol. 2019 Apr;49(4):600-610. doi: 10.1002/eji.201847801. Epub 2019 Feb 7.


PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway.

Dirk BS, End C, Pawlak EN, Van Nynatten LR, Jacob RA, Heit B, Dikeakos JD.

Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):519-525. doi: 10.1016/j.bbrc.2018.11.085. Epub 2018 Nov 17.


Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997).

Van Nynatten LR, Johnson AL, Dirk BS, Pawlak EN, Jacob RA, Haeryfar SMM, Dikeakos JD.

Viruses. 2018 Sep 13;10(9). pii: E493. doi: 10.3390/v10090493.


The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells.

Pawlak EN, Dirk BS, Jacob RA, Johnson AL, Dikeakos JD.

Retrovirology. 2018 Jan 12;15(1):6. doi: 10.1186/s12977-018-0388-3.


The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis.

Jacob RA, Johnson AL, Pawlak EN, Dirk BS, Van Nynatten LR, Haeryfar SMM, Dikeakos JD.

Virology. 2017 Sep;509:1-10. doi: 10.1016/j.virol.2017.05.018. Epub 2017 Jun 1.


HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling.

Dirk BS, Pawlak EN, Johnson AL, Van Nynatten LR, Jacob RA, Heit B, Dikeakos JD.

Sci Rep. 2016 Nov 14;6:37021. doi: 10.1038/srep37021.


Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways.

Dirk BS, Jacob RA, Johnson AL, Pawlak EN, Cavanagh PC, Van Nynatten L, Haeryfar SM, Dikeakos JD.

PLoS One. 2015 Apr 27;10(4):e0125619. doi: 10.1371/journal.pone.0125619. eCollection 2015.


HIV-1 Nef: a master manipulator of the membrane trafficking machinery mediating immune evasion.

Pawlak EN, Dikeakos JD.

Biochim Biophys Acta. 2015 Apr;1850(4):733-41. doi: 10.1016/j.bbagen.2015.01.003. Epub 2015 Jan 10. Review.


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