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Items: 1 to 50 of 86

1.

Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.

Makvandi M, Lee H, Puentes LN, Reilly SW, Rathi KS, Weng CC, Chan HS, Hou C, Raman P, Martinez D, Xu K, Carlin SD, Greenberg RA, Pawel BR, Mach RH, Maris JM, Pryma DA.

Mol Cancer Ther. 2019 Jul;18(7):1195-1204. doi: 10.1158/1535-7163.MCT-18-0837. Epub 2019 May 9.

PMID:
31072830
2.

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.

Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau9732. doi: 10.1126/scitranslmed.aau9732.

PMID:
30867324
3.

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.

Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG.

Int J Cancer. 2019 Jun 1;144(11):2707-2717. doi: 10.1002/ijc.32006. Epub 2019 Jan 15.

PMID:
30565669
4.

SMARCB1-deficient Tumors of Childhood: A Practical Guide.

Pawel BR.

Pediatr Dev Pathol. 2018 Jan-Feb;21(1):6-28. doi: 10.1177/1093526617749671. Epub 2017 Dec 27. Review.

PMID:
29280680
5.

Assessment of programmed death-ligand 1 expression and tumor-associated immune cells in pediatric cancer tissues.

Majzner RG, Simon JS, Grosso JF, Martinez D, Pawel BR, Santi M, Merchant MS, Geoerger B, Hezam I, Marty V, Vielh P, Daugaard M, Sorensen PH, Mackall CL, Maris JM.

Cancer. 2017 Oct 1;123(19):3807-3815. doi: 10.1002/cncr.30724. Epub 2017 Jun 13.

6.

Frequency and pathogenesis of central liver nodules in Alagille syndrome patients: Reply to Libbrecht and Cassiman.

Rapp JB, Bellah RD, Maya C, Pawel BR, Anupindi SA.

Pediatr Radiol. 2017 Jul;47(8):1025. doi: 10.1007/s00247-017-3881-2. Epub 2017 May 6. No abstract available.

PMID:
28478502
7.

Advancing Clinicopathologic Diagnosis of High-risk Neuroblastoma Using Computerized Image Analysis and Proteomic Profiling.

Niazi MKK, Chung JH, Heaton-Johnson KJ, Martinez D, Castellanos R, Irwin MS, Master SR, Pawel BR, Gurcan MN, Weiser DA.

Pediatr Dev Pathol. 2017 Sep-Oct;20(5):394-402. doi: 10.1177/1093526617698603. Epub 2017 Apr 18.

PMID:
28420318
8.

Multimodality imaging findings of massive ovarian edema in children.

Dahmoush H, Anupindi SA, Pawel BR, Chauvin NA.

Pediatr Radiol. 2017 May;47(5):576-583. doi: 10.1007/s00247-017-3782-4. Epub 2017 Feb 28.

PMID:
28246900
9.

Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma.

Li Y, Pawel BR, Hill DA, Epstein JI, Argani P.

Am J Surg Pathol. 2017 Apr;41(4):472-481. doi: 10.1097/PAS.0000000000000816.

10.

Xanthogranulomatous Pyelonephritis Manifesting as a Nephrocutaneous Fistula in a 5-Year-Old Female.

Zambrano IA, Van Batavia J, Bonzo J, Pawel BR, Long CJ.

Urology. 2017 Jul;105:24-28. doi: 10.1016/j.urology.2017.01.023. Epub 2017 Jan 25. No abstract available.

PMID:
28131924
11.

Fetal Lymphatic Malformations: More Variable Than We Think?

Oliver ER, Coleman BG, DeBari SE, Victoria T, Looney DM, Horii SC, Moldenhauer JS, Langer JE, Howell LJ, Pawel BR, Adzick NS.

J Ultrasound Med. 2017 May;36(5):1051-1058. doi: 10.7863/ultra.16.04071. Epub 2017 Jan 27.

PMID:
28127788
12.

Giant hepatic regenerative nodules in Alagille syndrome.

Rapp JB, Bellah RD, Maya C, Pawel BR, Anupindi SA.

Pediatr Radiol. 2017 Feb;47(2):197-204. doi: 10.1007/s00247-016-3728-2. Epub 2016 Oct 28.

PMID:
27796468
13.

The 'hole' story of a lung: Answers.

Kakajiwala A, Fernandes P, Pawel BR, Amaral S.

Pediatr Nephrol. 2017 May;32(5):777-779. doi: 10.1007/s00467-016-3454-x. Epub 2016 Jul 18. No abstract available.

PMID:
27432361
14.

The 'hole' story of a lung: Questions.

Kakajiwala A, Fernandes P, Pawel BR, Amaral S.

Pediatr Nephrol. 2017 May;32(5):773-775. doi: 10.1007/s00467-016-3453-y. Epub 2016 Jul 18. No abstract available.

PMID:
27432360
15.

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.

Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.

Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.

16.

Hypertension and proteinuria-the needle in the haystack?: Answers.

Denburg MR, Surrey LF, Pawel BR, Kaplan BS.

Pediatr Nephrol. 2016 Sep;31(9):1457-8. doi: 10.1007/s00467-015-3128-0. Epub 2015 May 28. No abstract available.

17.

Hypertension and proteinuria-the needle in the haystack?: Questions.

Denburg MR, Surrey LF, Pawel BR, Kaplan BS.

Pediatr Nephrol. 2016 Sep;31(9):1455-6. doi: 10.1007/s00467-015-3127-1. Epub 2015 May 28. No abstract available.

PMID:
26018122
18.

Serine catabolism regulates mitochondrial redox control during hypoxia.

Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB.

Cancer Discov. 2014 Dec;4(12):1406-17. doi: 10.1158/2159-8290.CD-14-0250. Epub 2014 Sep 3.

19.

Significant immunohistochemical expression of human chorionic gonadotropin in high-grade osteosarcoma is rare, but may be associated with clinically elevated serum levels.

Lee AF, Pawel BR, Sullivan LM.

Pediatr Dev Pathol. 2014 Jul-Aug;17(4):278-85. doi: 10.2350/14-02-1436-OA.1. Epub 2014 May 23.

PMID:
24856811
20.

Immunohistochemical expression of glypican-3 in pediatric tumors: an analysis of 414 cases.

Chan ES, Pawel BR, Corao DA, Venneti S, Russo P, Santi M, Sullivan LM.

Pediatr Dev Pathol. 2013 Jul-Aug;16(4):272-7. doi: 10.2350/12-06-1216-OA.1. Epub 2013 Mar 26.

PMID:
23530909
21.

Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group.

Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR.

J Clin Oncol. 2012 Nov 20;30(33):4148-54. doi: 10.1200/JCO.2011.41.5703. Epub 2012 Oct 22. Erratum in: J Clin Oncol. 2015 Mar 1;33(7):814. Dosage error in article text.

22.

Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions.

Sullivan LM, Folpe AL, Pawel BR, Judkins AR, Biegel JA.

Mod Pathol. 2013 Mar;26(3):385-92. doi: 10.1038/modpathol.2012.175. Epub 2012 Oct 12.

23.

Clonal trisomy 4 cells detected in the ossifying renal tumor of infancy: study of 3 cases.

Liu J, Guzman MA, Pawel BR, Pezanowski DM, Patel DM, Roth JA, Halligan GE, de Chadarévian JP.

Mod Pathol. 2013 Feb;26(2):275-81. doi: 10.1038/modpathol.2012.120. Epub 2012 Sep 14.

24.

Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.

Bosse KR, Diskin SJ, Cole KA, Wood AC, Schnepp RW, Norris G, Nguyen le B, Jagannathan J, Laquaglia M, Winter C, Diamond M, Hou C, Attiyeh EF, Mosse YP, Pineros V, Dizin E, Zhang Y, Asgharzadeh S, Seeger RC, Capasso M, Pawel BR, Devoto M, Hakonarson H, Rappaport EF, Irminger-Finger I, Maris JM.

Cancer Res. 2012 Apr 15;72(8):2068-78. doi: 10.1158/0008-5472.CAN-11-3703. Epub 2012 Feb 20.

25.

Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma.

Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mossé YP.

Oncogene. 2012 Nov 15;31(46):4859-67. doi: 10.1038/onc.2011.647. Epub 2012 Jan 23. Erratum in: Oncogene. 2012 Nov 15;31(46):4888. Vigny, M [added]; Mazot, P [added].

26.

Expression of therapeutic targets in Ewing sarcoma family tumors.

Ahmed AA, Sherman AK, Pawel BR.

Hum Pathol. 2012 Jul;43(7):1077-83. doi: 10.1016/j.humpath.2011.09.001. Epub 2011 Dec 21.

PMID:
22196127
27.

Claudin-6 is a nonspecific marker for malignant rhabdoid and other pediatric tumors.

Sullivan LM, Yankovich T, Le P, Martinez D, Santi M, Biegel JA, Pawel BR, Judkins AR.

Am J Surg Pathol. 2012 Jan;36(1):73-80. doi: 10.1097/PAS.0b013e31822cfa7e.

28.

Polyps and masses of the pediatric urinary bladder: a 21-year pathology review.

Huppmann AR, Pawel BR.

Pediatr Dev Pathol. 2011 Nov-Dec;14(6):438-44. doi: 10.2350/11-01-0958-OA.1. Epub 2011 Jul 27.

PMID:
21793666
29.

Eosinophilic fasciitis mimicking angioedema and treatment response to infliximab in a pediatric patient.

Poliak N, Orange JS, Pawel BR, Weiss PF.

Ann Allergy Asthma Immunol. 2011 May;106(5):444-5. doi: 10.1016/j.anai.2011.01.021. Epub 2011 Feb 23. No abstract available.

PMID:
21530881
30.

Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children's Oncology Group.

Borinstein SC, Barkauskas DA, Krailo M, Scher D, Scher L, Schlottmann S, Kallakury B, Dickman PS, Pawel BR, West DC, Womer RB, Toretsky JA.

Cancer. 2011 Nov 1;117(21):4966-76. doi: 10.1002/cncr.26112. Epub 2011 Apr 8.

31.

EWSR1-POU5F1 fusion in soft tissue myoepithelial tumors. A molecular analysis of sixty-six cases, including soft tissue, bone, and visceral lesions, showing common involvement of the EWSR1 gene.

Antonescu CR, Zhang L, Chang NE, Pawel BR, Travis W, Katabi N, Edelman M, Rosenberg AE, Nielsen GP, Dal Cin P, Fletcher CD.

Genes Chromosomes Cancer. 2010 Dec;49(12):1114-24. doi: 10.1002/gcc.20819.

32.

Congenital epulis.

Bewley A, Bloom JD, Kherani S, Pawel BR.

Ear Nose Throat J. 2010 Jul;89(7):299-300. No abstract available.

PMID:
20628985
33.

Congenital peribronchial myofibroblastic tumor: comparison of fetal and postnatal morphology.

Huppmann AR, Coffin CM, Hoot AC, Kahwash S, Pawel BR.

Pediatr Dev Pathol. 2011 Mar-Apr;14(2):124-9. doi: 10.2350/09-12-0767-CR.1. Epub 2010 Apr 5.

PMID:
20367454
34.

High expression of the PAX3-FKHR oncoprotein is required to promote tumorigenesis of human myoblasts.

Xia SJ, Holder DD, Pawel BR, Zhang C, Barr FG.

Am J Pathol. 2009 Dec;175(6):2600-8. doi: 10.2353/ajpath.2009.090192. Epub 2009 Nov 5.

35.

Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors in vivo.

Reid GS, Shan X, Coughlin CM, Lassoued W, Pawel BR, Wexler LH, Thiele CJ, Tsokos M, Pinkus JL, Pinkus GS, Grupp SA, Vonderheide RH.

Clin Cancer Res. 2009 Nov 1;15(21):6602-8. doi: 10.1158/1078-0432.CCR-09-0829. Epub 2009 Oct 13.

36.

Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.

Lestini BJ, Goldsmith KC, Fluchel MN, Liu X, Chen NL, Goyal B, Pawel BR, Hogarty MD.

Cancer Biol Ther. 2009 Aug;8(16):1587-95. Epub 2009 Aug 8.

37.

Thyroid transcription factor-1 expression in normal gynecologic tissues and its potential significance.

Niu HL, Pasha TL, Pawel BR, LiVolsi VA, Zhang PJ.

Int J Gynecol Pathol. 2009 Jul;28(4):301-7. doi: 10.1097/PGP.0b013e31819901c6.

PMID:
19483637
38.

Loss of INI1 expression defines a unique subset of pediatric undifferentiated soft tissue sarcomas.

Kreiger PA, Judkins AR, Russo PA, Biegel JA, Lestini BJ, Assanasen C, Pawel BR.

Mod Pathol. 2009 Jan;22(1):142-50. doi: 10.1038/modpathol.2008.185. Epub 2008 Nov 7.

39.

ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.

Corao DA, Biegel JA, Coffin CM, Barr FG, Wainwright LM, Ernst LM, Choi JK, Zhang PJ, Pawel BR.

Pediatr Dev Pathol. 2009 Jul-Aug;12(4):275-83. doi: 10.2350/08-03-0434.1.

PMID:
18788887
40.

Recurrent pedal hobnail (Dabska-retiform) hemangioendothelioma with forefoot reconstructive surgery using a digital fillet flap.

Yarmel D, Dormans JP, Pawel BR, Chang B.

J Foot Ankle Surg. 2008 Sep-Oct;47(5):487-93. doi: 10.1053/j.jfas.2008.06.004. Epub 2008 Jul 31.

PMID:
18725133
41.

CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.

Fujita T, Igarashi J, Okawa ER, Gotoh T, Manne J, Kolla V, Kim J, Zhao H, Pawel BR, London WB, Maris JM, White PS, Brodeur GM.

J Natl Cancer Inst. 2008 Jul 2;100(13):940-9. doi: 10.1093/jnci/djn176. Epub 2008 Jun 24.

42.

Schistosomiasis: an unexpected finding in an inguinal hernia sac.

Pawel BR, Osman J, Nance ML, McGowan KL.

Pediatr Dev Pathol. 2008 Sep-Oct;11(5):402-4. Epub 2007 Jun 7.

PMID:
17990928
43.

Atraumatic compartment syndrome: a manifestation of toxic shock and infectious pyomyositis in a child. A case report.

Park S, Shatsky JB, Pawel BR, Wells L.

J Bone Joint Surg Am. 2007 Jun;89(6):1337-42. No abstract available.

PMID:
17545439
44.

Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas.

Laé M, Ahn EH, Mercado GE, Chuai S, Edgar M, Pawel BR, Olshen A, Barr FG, Ladanyi M.

J Pathol. 2007 Jun;212(2):143-51.

PMID:
17471488
45.

Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma.

Coughlin CM, Fleming MD, Carroll RG, Pawel BR, Hogarty MD, Shan X, Vance BA, Cohen JN, Jairaj S, Lord EM, Wexler MH, Danet-Desnoyers GA, Pinkus JL, Pinkus GS, Maris JM, Grupp SA, Vonderheide RH.

J Clin Oncol. 2006 Dec 20;24(36):5725-34.

PMID:
17179106
46.

The glomangioma in the differential diagnosis of vascular malformations.

Myers RS, Lo AK, Pawel BR.

Ann Plast Surg. 2006 Oct;57(4):443-6.

PMID:
16998340
47.

The value of the metabolic autopsy in the pediatric hospital setting.

Ernst LM, Sondheimer N, Deardorff MA, Bennett MJ, Pawel BR.

J Pediatr. 2006 Jun;148(6):779-83.

PMID:
16769386
48.

Idiopathic infantile arterial calcification: two case reports, a review of the literature and a role for cardiac transplantation.

Glatz AC, Pawel BR, Hsu DT, Weinberg P, Chrisant MR.

Pediatr Transplant. 2006 Mar;10(2):225-33. Review.

PMID:
16573612
49.

Langerhans cell histiocytosis and human herpes virus 6 (HHV-6), an analysis by real-time polymerase chain reaction.

Glotzbecker MP, Dormans JP, Pawel BR, Wills BP, Joshi Y, Elkan M, Hodinka RL.

J Orthop Res. 2006 Mar;24(3):313-20.

50.

Two novel TP63 mutations associated with the ankyloblepharon, ectodermal defects, and cleft lip and palate syndrome: a skin fragility phenotype.

Payne AS, Yan AC, Ilyas E, Li W, Seykora JT, Young TL, Pawel BR, Honig PJ, Camacho J, Imaizumi S, Heymann WR, Schnur RE.

Arch Dermatol. 2005 Dec;141(12):1567-73.

PMID:
16365259

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