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Items: 1 to 50 of 131

1.

SWI/SNF complex heterogeneity relates with polyphenotypic differentiation, prognosis and immune response in rhabdoid tumors.

Panwalkar P, Pratt D, Chung C, Dang D, Le P, Martinez D, Bayliss JM, Smith KS, Adam M, Potter S, Northcott P, Mascarenhas L, Shows J, Pawel B, Margol A, Huang A, Judkins AR, Venneti S.

Neuro Oncol. 2020 Jan 8. pii: noaa004. doi: 10.1093/neuonc/noaa004. [Epub ahead of print]

PMID:
31912158
2.

Phase I Clinical Trial of the Wee1 Inhibitor Adavosertib (AZD1775) with Irinotecan in Children with Relapsed Solid Tumors. A COG Phase I Consortium Report (ADVL1312).

Cole KA, Pal S, Kudgus RA, Ijaz H, Liu X, Minard CG, Pawel BR, Maris JM, Haas-Kogan DA, Voss SD, Berg SL, Reid JM, Fox E, Weigel BJ.

Clin Cancer Res. 2019 Dec 19. doi: 10.1158/1078-0432.CCR-19-3470. [Epub ahead of print]

PMID:
31857431
3.

Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.

Makvandi M, Lee H, Puentes LN, Reilly SW, Rathi KS, Weng CC, Chan HS, Hou C, Raman P, Martinez D, Xu K, Carlin SD, Greenberg RA, Pawel BR, Mach RH, Maris JM, Pryma DA.

Mol Cancer Ther. 2019 Jul;18(7):1195-1204. doi: 10.1158/1535-7163.MCT-18-0837. Epub 2019 May 9.

PMID:
31072830
4.

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.

Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau9732. doi: 10.1126/scitranslmed.aau9732.

PMID:
30867324
5.

Systemic manifestations of extraskeletal myxoid chondrosarcoma associated with a novel t(2;22)(q34;q12) EWS translocation in a child and a review of the literature.

Batsis ID, Offenbacher R, Rybinski B, Pawel B, Weiser DA.

Pediatr Hematol Oncol. 2018 Oct - Nov;35(7-8):434-441. doi: 10.1080/08880018.2018.1557766. Epub 2019 Feb 18. Review.

PMID:
30776935
6.

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.

Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG.

Int J Cancer. 2019 Jun 1;144(11):2707-2717. doi: 10.1002/ijc.32006. Epub 2019 Jan 15.

PMID:
30565669
7.

Diffuse Strong BCOR Immunoreactivity Is a Sensitive and Specific Marker for Clear Cell Sarcoma of the Kidney (CCSK) in Pediatric Renal Neoplasia.

Argani P, Pawel B, Szabo S, Reyes-Múgica M, Timmons C, Antonescu CR.

Am J Surg Pathol. 2018 Aug;42(8):1128-1131. doi: 10.1097/PAS.0000000000001089. No abstract available.

8.

SMARCB1-deficient Tumors of Childhood: A Practical Guide.

Pawel BR.

Pediatr Dev Pathol. 2018 Jan-Feb;21(1):6-28. doi: 10.1177/1093526617749671. Epub 2017 Dec 27. Review.

PMID:
29280680
9.

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Bosse KR, Raman P, Zhu Z, Lane M, Martinez D, Heitzeneder S, Rathi KS, Kendsersky NM, Randall M, Donovan L, Morrissy S, Sussman RT, Zhelev DV, Feng Y, Wang Y, Hwang J, Lopez G, Harenza JL, Wei JS, Pawel B, Bhatti T, Santi M, Ganguly A, Khan J, Marra MA, Taylor MD, Dimitrov DS, Mackall CL, Maris JM.

Cancer Cell. 2017 Sep 11;32(3):295-309.e12. doi: 10.1016/j.ccell.2017.08.003.

10.

Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.

Cheema A, Arkader A, Pawel B.

Skeletal Radiol. 2017 Oct;46(10):1447-1452. doi: 10.1007/s00256-017-2707-5. Epub 2017 Jun 28. Review.

PMID:
28660405
11.

Assessment of programmed death-ligand 1 expression and tumor-associated immune cells in pediatric cancer tissues.

Majzner RG, Simon JS, Grosso JF, Martinez D, Pawel BR, Santi M, Merchant MS, Geoerger B, Hezam I, Marty V, Vielh P, Daugaard M, Sorensen PH, Mackall CL, Maris JM.

Cancer. 2017 Oct 1;123(19):3807-3815. doi: 10.1002/cncr.30724. Epub 2017 Jun 13.

12.

Frequency and pathogenesis of central liver nodules in Alagille syndrome patients: Reply to Libbrecht and Cassiman.

Rapp JB, Bellah RD, Maya C, Pawel BR, Anupindi SA.

Pediatr Radiol. 2017 Jul;47(8):1025. doi: 10.1007/s00247-017-3881-2. Epub 2017 May 6. No abstract available.

PMID:
28478502
13.

Advancing Clinicopathologic Diagnosis of High-risk Neuroblastoma Using Computerized Image Analysis and Proteomic Profiling.

Niazi MKK, Chung JH, Heaton-Johnson KJ, Martinez D, Castellanos R, Irwin MS, Master SR, Pawel BR, Gurcan MN, Weiser DA.

Pediatr Dev Pathol. 2017 Sep-Oct;20(5):394-402. doi: 10.1177/1093526617698603. Epub 2017 Apr 18.

PMID:
28420318
14.

Multimodality imaging findings of massive ovarian edema in children.

Dahmoush H, Anupindi SA, Pawel BR, Chauvin NA.

Pediatr Radiol. 2017 May;47(5):576-583. doi: 10.1007/s00247-017-3782-4. Epub 2017 Feb 28.

PMID:
28246900
15.

Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma.

Li Y, Pawel BR, Hill DA, Epstein JI, Argani P.

Am J Surg Pathol. 2017 Apr;41(4):472-481. doi: 10.1097/PAS.0000000000000816.

16.

Xanthogranulomatous Pyelonephritis Manifesting as a Nephrocutaneous Fistula in a 5-Year-Old Female.

Zambrano IA, Van Batavia J, Bonzo J, Pawel BR, Long CJ.

Urology. 2017 Jul;105:24-28. doi: 10.1016/j.urology.2017.01.023. Epub 2017 Jan 25. No abstract available.

PMID:
28131924
17.

Fetal Lymphatic Malformations: More Variable Than We Think?

Oliver ER, Coleman BG, DeBari SE, Victoria T, Looney DM, Horii SC, Moldenhauer JS, Langer JE, Howell LJ, Pawel BR, Adzick NS.

J Ultrasound Med. 2017 May;36(5):1051-1058. doi: 10.7863/ultra.16.04071. Epub 2017 Jan 27.

PMID:
28127788
18.

Giant hepatic regenerative nodules in Alagille syndrome.

Rapp JB, Bellah RD, Maya C, Pawel BR, Anupindi SA.

Pediatr Radiol. 2017 Feb;47(2):197-204. doi: 10.1007/s00247-016-3728-2. Epub 2016 Oct 28.

PMID:
27796468
19.

Retropharyngeal Abscess and Mediastinitis in a Well-Appearing Infant With Prolonged Fever.

Vinograd AM, Zonfrillo MR, Pawel B.

Pediatr Emerg Care. 2017 Jan;33(1):43-46. doi: 10.1097/PEC.0000000000000849.

PMID:
27548742
20.

The 'hole' story of a lung: Answers.

Kakajiwala A, Fernandes P, Pawel BR, Amaral S.

Pediatr Nephrol. 2017 May;32(5):777-779. doi: 10.1007/s00467-016-3454-x. Epub 2016 Jul 18. No abstract available.

PMID:
27432361
21.

The 'hole' story of a lung: Questions.

Kakajiwala A, Fernandes P, Pawel BR, Amaral S.

Pediatr Nephrol. 2017 May;32(5):773-775. doi: 10.1007/s00467-016-3453-y. Epub 2016 Jul 18. No abstract available.

PMID:
27432360
22.

Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma.

Liu Z, Lam N, Wang E, Virden RA, Pawel B, Attiyeh EF, Maris JM, Thiele CJ.

Oncogene. 2017 Jan 5;36(1):97-109. doi: 10.1038/onc.2016.179. Epub 2016 Jun 6.

23.

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.

Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW.

Science. 2016 May 13;352(6287):844-9. doi: 10.1126/science.aac7272.

24.

Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Evageliou NF, Haber M, Vu A, Laetsch TW, Murray J, Gamble LD, Cheng NC, Liu K, Reese M, Corrigan KA, Ziegler DS, Webber H, Hayes CS, Pawel B, Marshall GM, Zhao H, Gilmour SK, Norris MD, Hogarty MD.

Clin Cancer Res. 2016 Sep 1;22(17):4391-404. doi: 10.1158/1078-0432.CCR-15-2539. Epub 2016 Mar 24.

25.

T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma.

Singh N, Kulikovskaya I, Barrett DM, Binder-Scholl G, Jakobsen B, Martinez D, Pawel B, June CH, Kalos MD, Grupp SA.

Oncoimmunology. 2015 Aug 12;5(1):e1040216. eCollection 2016.

26.

Hypertension and proteinuria-the needle in the haystack?: Answers.

Denburg MR, Surrey LF, Pawel BR, Kaplan BS.

Pediatr Nephrol. 2016 Sep;31(9):1457-8. doi: 10.1007/s00467-015-3128-0. Epub 2015 May 28. No abstract available.

27.

Hypertension and proteinuria-the needle in the haystack?: Questions.

Denburg MR, Surrey LF, Pawel BR, Kaplan BS.

Pediatr Nephrol. 2016 Sep;31(9):1455-6. doi: 10.1007/s00467-015-3127-1. Epub 2015 May 28. No abstract available.

PMID:
26018122
28.

Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.

Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB.

Mol Cell. 2014 Oct 23;56(2):205-218. doi: 10.1016/j.molcel.2014.08.018. Epub 2014 Sep 18.

29.

Serine catabolism regulates mitochondrial redox control during hypoxia.

Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB.

Cancer Discov. 2014 Dec;4(12):1406-17. doi: 10.1158/2159-8290.CD-14-0250. Epub 2014 Sep 3.

30.

Malignant rhabdoid tumor of the bladder and ganglioglioma in a 14 year-old male with a germline 22q11.2 deletion.

Bosse KR, Shukla AR, Pawel B, Chikwava KR, Santi M, Tooke L, Castagna K, Biegel JA, Bagatell R.

Cancer Genet. 2014 Sep;207(9):415-9. doi: 10.1016/j.cancergen.2014.05.007. Epub 2014 May 21.

PMID:
25018128
31.

Significant immunohistochemical expression of human chorionic gonadotropin in high-grade osteosarcoma is rare, but may be associated with clinically elevated serum levels.

Lee AF, Pawel BR, Sullivan LM.

Pediatr Dev Pathol. 2014 Jul-Aug;17(4):278-85. doi: 10.2350/14-02-1436-OA.1. Epub 2014 May 23.

PMID:
24856811
32.

Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic leukemia and mediastinal germ cell tumor.

Oshrine BR, Olsen MN, Heneghan M, Wertheim G, Daber R, Wilmoth DM, Biegel JA, Pawel B, Aplenc R, King RL.

Cancer Genet. 2014 Apr;207(4):153-9. doi: 10.1016/j.cancergen.2014.03.009. Epub 2014 Apr 5.

PMID:
24831771
33.

High ALK mRNA expression has a negative prognostic significance in rhabdomyosarcoma.

Bonvini P, Zin A, Alaggio R, Pawel B, Bisogno G, Rosolen A.

Br J Cancer. 2013 Dec 10;109(12):3084-91. doi: 10.1038/bjc.2013.653. Epub 2013 Oct 22.

34.

Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma.

Rader J, Russell MR, Hart LS, Nakazawa MS, Belcastro LT, Martinez D, Li Y, Carpenter EL, Attiyeh EF, Diskin SJ, Kim S, Parasuraman S, Caponigro G, Schnepp RW, Wood AC, Pawel B, Cole KA, Maris JM.

Clin Cancer Res. 2013 Nov 15;19(22):6173-82. doi: 10.1158/1078-0432.CCR-13-1675. Epub 2013 Sep 17.

35.

Mutations in the ABCC6 gene as a cause of generalized arterial calcification of infancy: genotypic overlap with pseudoxanthoma elasticum.

Li Q, Brodsky JL, Conlin LK, Pawel B, Glatz AC, Gafni RI, Schurgers L, Uitto J, Hakonarson H, Deardorff MA, Levine MA.

J Invest Dermatol. 2014 Mar;134(3):658-665. doi: 10.1038/jid.2013.370. Epub 2013 Sep 5.

36.

Acanthosis nigricans associated with an adrenocortical tumor in a pediatric patient.

Isaacoff E, Dimitriadi FF, Barrows F, Pawel B, Mattei P, Mostoufi-Moab S.

Case Rep Endocrinol. 2013;2013:174593. doi: 10.1155/2013/174593. Epub 2013 May 30.

37.

Immunohistochemical expression of glypican-3 in pediatric tumors: an analysis of 414 cases.

Chan ES, Pawel BR, Corao DA, Venneti S, Russo P, Santi M, Sullivan LM.

Pediatr Dev Pathol. 2013 Jul-Aug;16(4):272-7. doi: 10.2350/12-06-1216-OA.1. Epub 2013 Mar 26.

PMID:
23530909
38.

Combination therapy targeting the Chk1 and Wee1 kinases shows therapeutic efficacy in neuroblastoma.

Russell MR, Levin K, Rader J, Belcastro L, Li Y, Martinez D, Pawel B, Shumway SD, Maris JM, Cole KA.

Cancer Res. 2013 Jan 15;73(2):776-84. doi: 10.1158/0008-5472.CAN-12-2669. Epub 2012 Nov 7.

39.

Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group.

Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR.

J Clin Oncol. 2012 Nov 20;30(33):4148-54. doi: 10.1200/JCO.2011.41.5703. Epub 2012 Oct 22. Erratum in: J Clin Oncol. 2015 Mar 1;33(7):814. Dosage error in article text.

40.

Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions.

Sullivan LM, Folpe AL, Pawel BR, Judkins AR, Biegel JA.

Mod Pathol. 2013 Mar;26(3):385-92. doi: 10.1038/modpathol.2012.175. Epub 2012 Oct 12.

41.

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group.

Dubois SG, Geier E, Batra V, Yee SW, Neuhaus J, Segal M, Martinez D, Pawel B, Yanik G, Naranjo A, London WB, Kreissman S, Baker D, Attiyeh E, Hogarty MD, Maris JM, Giacomini K, Matthay KK.

Int J Mol Imaging. 2012;2012:250834. doi: 10.1155/2012/250834. Epub 2012 Sep 25.

42.

Clonal trisomy 4 cells detected in the ossifying renal tumor of infancy: study of 3 cases.

Liu J, Guzman MA, Pawel BR, Pezanowski DM, Patel DM, Roth JA, Halligan GE, de Chadarévian JP.

Mod Pathol. 2013 Feb;26(2):275-81. doi: 10.1038/modpathol.2012.120. Epub 2012 Sep 14.

43.

Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.

Bosse KR, Diskin SJ, Cole KA, Wood AC, Schnepp RW, Norris G, Nguyen le B, Jagannathan J, Laquaglia M, Winter C, Diamond M, Hou C, Attiyeh EF, Mosse YP, Pineros V, Dizin E, Zhang Y, Asgharzadeh S, Seeger RC, Capasso M, Pawel BR, Devoto M, Hakonarson H, Rappaport EF, Irminger-Finger I, Maris JM.

Cancer Res. 2012 Apr 15;72(8):2068-78. doi: 10.1158/0008-5472.CAN-11-3703. Epub 2012 Feb 20.

44.

Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma.

Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mossé YP.

Oncogene. 2012 Nov 15;31(46):4859-67. doi: 10.1038/onc.2011.647. Epub 2012 Jan 23. Erratum in: Oncogene. 2012 Nov 15;31(46):4888. Vigny, M [added]; Mazot, P [added].

45.

Expression of therapeutic targets in Ewing sarcoma family tumors.

Ahmed AA, Sherman AK, Pawel BR.

Hum Pathol. 2012 Jul;43(7):1077-83. doi: 10.1016/j.humpath.2011.09.001. Epub 2011 Dec 21.

PMID:
22196127
46.

Claudin-6 is a nonspecific marker for malignant rhabdoid and other pediatric tumors.

Sullivan LM, Yankovich T, Le P, Martinez D, Santi M, Biegel JA, Pawel BR, Judkins AR.

Am J Surg Pathol. 2012 Jan;36(1):73-80. doi: 10.1097/PAS.0b013e31822cfa7e.

47.

Malignant rhabdoid tumors express stem cell factors, which relate to the expression of EZH2 and Id proteins.

Venneti S, Le P, Martinez D, Xie SX, Sullivan LM, Rorke-Adams LB, Pawel B, Judkins AR.

Am J Surg Pathol. 2011 Oct;35(10):1463-72. doi: 10.1097/PAS.0b013e318224d2cd.

PMID:
21921784
48.

Polyps and masses of the pediatric urinary bladder: a 21-year pathology review.

Huppmann AR, Pawel BR.

Pediatr Dev Pathol. 2011 Nov-Dec;14(6):438-44. doi: 10.2350/11-01-0958-OA.1. Epub 2011 Jul 27.

PMID:
21793666
49.

p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors.

Venneti S, Le P, Martinez D, Eaton KW, Shyam N, Jordan-Sciutto KL, Pawel B, Biegel JA, Judkins AR.

J Neuropathol Exp Neurol. 2011 Jul;70(7):596-609. doi: 10.1097/NEN.0b013e31822146ca.

50.

Eosinophilic fasciitis mimicking angioedema and treatment response to infliximab in a pediatric patient.

Poliak N, Orange JS, Pawel BR, Weiss PF.

Ann Allergy Asthma Immunol. 2011 May;106(5):444-5. doi: 10.1016/j.anai.2011.01.021. Epub 2011 Feb 23. No abstract available.

PMID:
21530881

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