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Items: 29

1.

Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse.

Mayeux JM, Escalante GM, Christy JM, Pawar RD, Kono DH, Pollard KM.

Front Immunol. 2018 Apr 26;9:874. doi: 10.3389/fimmu.2018.00874. eCollection 2018.

2.

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN.

Pollard KM, Escalante GM, Huang H, Haraldsson KM, Hultman P, Christy JM, Pawar RD, Mayeux JM, Gonzalez-Quintial R, Baccala R, Beutler B, Theofilopoulos AN, Kono DH.

J Immunol. 2017 Dec 1;199(11):3739-3747. doi: 10.4049/jimmunol.1700332. Epub 2017 Oct 20.

3.

A peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigens.

Xia Y, Eryilmaz E, Der E, Pawar RD, Guo X, Cowburn D, Putterman C.

Clin Exp Immunol. 2016 Mar;183(3):369-79. doi: 10.1111/cei.12734. Epub 2015 Dec 8.

4.

Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors.

Jacob CO, Yu N, Sindhava V, Cancro MP, Pawar RD, Putterman C, Stohl W.

Arthritis Rheumatol. 2015 Sep;67(9):2523-35. doi: 10.1002/art.39210.

5.

Deficiency of fibroblast growth factor-inducible 14 (Fn14) preserves the filtration barrier and ameliorates lupus nephritis.

Xia Y, Herlitz LC, Gindea S, Wen J, Pawar RD, Misharin A, Perlman H, Wu L, Wu P, Michaelson JS, Burkly LC, Putterman C.

J Am Soc Nephrol. 2015 May;26(5):1053-70. doi: 10.1681/ASN.2014030233. Epub 2014 Sep 30.

6.

B7x/B7-H4 modulates the adaptive immune response and ameliorates renal injury in antibody-mediated nephritis.

Pawar RD, Goilav B, Xia Y, Herlitz L, Doerner J, Chalmers S, Ghosh K, Zang X, Putterman C.

Clin Exp Immunol. 2015 Feb;179(2):329-43. doi: 10.1111/cei.12452.

7.

Serum autoantibodies in pristane induced lupus are regulated by neutrophil gelatinase associated lipocalin.

Pawar RD, Goilav B, Xia Y, Zhuang H, Herlitz L, Reeves WH, Putterman C.

Clin Immunol. 2014 Sep;154(1):49-65. doi: 10.1016/j.clim.2014.06.007. Epub 2014 Jun 24.

8.

Inflammatory response following neutrophil recovery postchemotherapy in acute myeloid leukemia cases without evidence of infection: role of homing of neutrophils.

Pawar RD, Williams T, Khera R, Eid A, Aljitawi OS, Dusing RW.

J Blood Med. 2014 Mar 10;5:37-41. doi: 10.2147/JBM.S53616. eCollection 2014.

9.

The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies.

Xia Y, Pawar RD, Nakouzi AS, Herlitz L, Broder A, Liu K, Goilav B, Fan M, Wang L, Li QZ, Casadevall A, Putterman C.

J Autoimmun. 2012 Dec;39(4):398-411. doi: 10.1016/j.jaut.2012.06.005. Epub 2012 Jul 28.

10.

Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice.

Jacob CO, Guo S, Jacob N, Pawar RD, Putterman C, Quinn WJ 3rd, Cancro MP, Migone TS, Stohl W.

Arthritis Rheum. 2012 May;64(5):1610-9. doi: 10.1002/art.33458.

11.

Neutrophil gelatinase-associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis in mice.

Pawar RD, Pitashny M, Gindea S, Tieng AT, Levine B, Goilav B, Campbell SR, Xia Y, Qing X, Thomas DB, Herlitz L, Berger T, Mak TW, Putterman C.

Arthritis Rheum. 2012 May;64(5):1620-31. doi: 10.1002/art.33485.

12.

Marginal zone precursor B cells as cellular agents for type I IFN-promoted antigen transport in autoimmunity.

Wang JH, Li J, Wu Q, Yang P, Pawar RD, Xie S, Timares L, Raman C, Chaplin DD, Lu L, Mountz JD, Hsu HC.

J Immunol. 2010 Jan 1;184(1):442-51. doi: 10.4049/jimmunol.0900870. Epub 2009 Nov 30.

13.

Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway.

Hägele H, Allam R, Pawar RD, Reichel CA, Krombach F, Anders HJ.

Am J Pathol. 2009 Nov;175(5):1896-904. doi: 10.2353/ajpath.2009.090182. Epub 2009 Oct 15.

14.

Double-stranded RNA activates type I interferon secretion in glomerular endothelial cells via retinoic acid-inducible gene (RIG)-1.

Hägele H, Allam R, Pawar RD, Anders HJ.

Nephrol Dial Transplant. 2009 Nov;24(11):3312-8. doi: 10.1093/ndt/gfp339. Epub 2009 Jul 16.

PMID:
19608629
15.

Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier.

Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Gröne HJ, Anders HJ.

Immunology. 2009 Sep;128(1 Suppl):e206-21. doi: 10.1111/j.1365-2567.2008.02948.x. Epub 2008 Oct 24.

16.

Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.

Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ.

Eur J Immunol. 2008 Dec;38(12):3487-98. doi: 10.1002/eji.200838604.

17.

Anti-Ccl2 Spiegelmer permits 75% dose reduction of cyclophosphamide to control diffuse proliferative lupus nephritis and pneumonitis in MRL-Fas(lpr) mice.

Kulkarni O, Eulberg D, Selve N, Zöllner S, Allam R, Pawar RD, Pfeiffer S, Segerer S, Klussmann S, Anders HJ.

J Pharmacol Exp Ther. 2009 Feb;328(2):371-7. doi: 10.1124/jpet.108.142711. Epub 2008 Nov 7.

PMID:
18997060
18.

Molecular mimicry in innate immunity? The viral RNA recognition receptor TLR7 accelerates murine lupus.

Anders HJ, Krug A, Pawar RD.

Eur J Immunol. 2008 Jul;38(7):1795-9. doi: 10.1002/eji.200838478.

19.

Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis.

Savarese E, Steinberg C, Pawar RD, Reindl W, Akira S, Anders HJ, Krug A.

Arthritis Rheum. 2008 Apr;58(4):1107-15. doi: 10.1002/art.23407.

20.

Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice.

Kulkarni O, Pawar RD, Purschke W, Eulberg D, Selve N, Buchner K, Ninichuk V, Segerer S, Vielhauer V, Klussmann S, Anders HJ.

J Am Soc Nephrol. 2007 Aug;18(8):2350-8. Epub 2007 Jul 11.

21.

Coactivation of Toll-like receptor-3 and -7 in immune complex glomerulonephritis.

Patole PS, Pawar RD, Lichtnekert J, Lech M, Kulkarni OP, Ramanjaneyulu A, Segerer S, Anders HJ.

J Autoimmun. 2007 Aug;29(1):52-9. Epub 2007 Jun 4.

PMID:
17544622
22.

Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus.

Pawar RD, Ramanjaneyulu A, Kulkarni OP, Lech M, Segerer S, Anders HJ.

J Am Soc Nephrol. 2007 Jun;18(6):1721-31. Epub 2007 Apr 25.

23.

Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis.

Pawar RD, Patole PS, Ellwart A, Lech M, Segerer S, Schlondorff D, Anders HJ.

J Am Soc Nephrol. 2006 Dec;17(12):3365-73. Epub 2006 Nov 2.

24.

Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.

Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ.

Nephrol Dial Transplant. 2006 Nov;21(11):3062-73. Epub 2006 Sep 5.

PMID:
16954173
25.

Microbial nucleic acids pay a Toll in kidney disease.

Pawar RD, Patole PS, Wörnle M, Anders HJ.

Am J Physiol Renal Physiol. 2006 Sep;291(3):F509-16. Epub 2006 Apr 4. Review.

26.

Toll-like receptor-7 modulates immune complex glomerulonephritis.

Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M, Schlöndorff D, Anders HJ.

J Am Soc Nephrol. 2006 Jan;17(1):141-9. Epub 2005 Nov 9.

27.

Molecular mechanisms of autoimmunity triggered by microbial infection.

Anders HJ, Zecher D, Pawar RD, Patole PS.

Arthritis Res Ther. 2005;7(5):215-24. Epub 2005 Aug 30. Review.

28.

G-rich DNA suppresses systemic lupus.

Patole PS, Zecher D, Pawar RD, Gröne HJ, Schlöndorff D, Anders HJ.

J Am Soc Nephrol. 2005 Nov;16(11):3273-80. Epub 2005 Sep 21.

29.

Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.

Ninichuk V, Gross O, Reichel C, Khandoga A, Pawar RD, Ciubar R, Segerer S, Belemezova E, Radomska E, Luckow B, Perez de Lema G, Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M, Krombach F, Schlöndorff D, Anders HJ.

J Am Soc Nephrol. 2005 Apr;16(4):977-85. Epub 2005 Feb 16.

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