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Items: 1 to 50 of 386

1.

Asthma impacts on workplace productivity in employed patients who are symptomatic despite background therapy: a multinational survey.

Gruffydd-Jones K, Thomas M, Roman-Rodríguez M, Infantino A, FitzGerald JM, Pavord I, Haddon JM, Elsasser U, Vogelberg C.

J Asthma Allergy. 2019 Jul 11;12:183-194. doi: 10.2147/JAA.S204278. eCollection 2019.

2.

Dupilumab Efficacy in Uncontrolled, Moderate-to-Severe Asthma With Self-reported Chronic Rhinosinusitis.

Maspero JF, Katelaris CH, Busse WW, Castro M, Corren J, Chipps BE, Peters AT, Pavord ID, Ford LB, Sher L, Rabe KF, Rice MS, Rowe P, Lu Y, Harel S, Jagerschmidt A, Khan A, Kamat S, Pirozzi G, Amin N, Ruddy M, Graham NMH, Mannent L, Teper A.

J Allergy Clin Immunol Pract. 2019 Jul 24. pii: S2213-2198(19)30633-6. doi: 10.1016/j.jaip.2019.07.016. [Epub ahead of print]

3.

Reply to: Inhaled Corticosteroids and Adult Asthma.

Beasley R, Harper J, Bird G, Maijers I, Weatherall M, Pavord ID.

Am J Respir Crit Care Med. 2019 Jul 24. doi: 10.1164/rccm.201907-1408LE. [Epub ahead of print] No abstract available.

PMID:
31339340
4.

Prognostic and predictive value of blood eosinophil count, fractional exhaled nitric oxide and their combination in severe asthma: a post-hoc analysis.

Shrimanker R, Keene O, Hynes G, Wenzel S, Yancey S, Pavord ID.

Am J Respir Crit Care Med. 2019 Jul 12. doi: 10.1164/rccm.201903-0599LE. [Epub ahead of print] No abstract available.

PMID:
31298922
5.

Severe T2-high asthma in the biologics era: European experts' opinion.

Pavord I, Bahmer T, Braido F, Cosío BG, Humbert M, Idzko M, Adamek L.

Eur Respir Rev. 2019 Jul 8;28(152). pii: 190054. doi: 10.1183/16000617.0054-2019. Print 2019 Jun 30. Review.

6.

Usability of mepolizumab single-use prefilled autoinjector for patient self-administration.

Bernstein D, Pavord ID, Chapman KR, Follows R, Bentley JH, Pouliquen I, Bradford E.

J Asthma. 2019 Jun 28:1-12. doi: 10.1080/02770903.2019.1630641. [Epub ahead of print]

PMID:
31251090
7.

Blood eosinophil count and GOLD stage predict response to maintenance azithromycin treatment in COPD patients with frequent exacerbations.

Djamin RS, Bafadhel M, Uzun S, Russell REK, Ermens AAM, Kerstens R, Aerts JGJV, Pavord ID, van der Eerden MM.

Respir Med. 2019 Jul - Aug;154:27-33. doi: 10.1016/j.rmed.2019.06.005. Epub 2019 Jun 8.

PMID:
31203097
8.

The acute wheezy adult with airways disease in the emergency department: a retrospective case-note review of exacerbations of COPD.

Russell R, Beer S, Pavord ID, Pullinger R, Bafadhel M.

Int J Chron Obstruct Pulmon Dis. 2019 May 7;14:971-977. doi: 10.2147/COPD.S190085. eCollection 2019.

9.

Controlled Trial of Budesonide-Formoterol as Needed for Mild Asthma.

Beasley R, Holliday M, Reddel HK, Braithwaite I, Ebmeier S, Hancox RJ, Harrison T, Houghton C, Oldfield K, Papi A, Pavord ID, Williams M, Weatherall M; Novel START Study Team.

N Engl J Med. 2019 May 23;380(21):2020-2030. doi: 10.1056/NEJMoa1901963. Epub 2019 May 19.

PMID:
31112386
10.

Asthma progression and mortality: the role of inhaled corticosteroids.

O'Byrne P, Fabbri LM, Pavord ID, Papi A, Petruzzelli S, Lange P.

Eur Respir J. 2019 Jul 18;54(1). pii: 1900491. doi: 10.1183/13993003.00491-2019. Print 2019 Jul. Review.

11.

Measuring lung function in airways diseases: current and emerging techniques.

Petousi N, Talbot NP, Pavord I, Robbins PA.

Thorax. 2019 Aug;74(8):797-805. doi: 10.1136/thoraxjnl-2018-212441. Epub 2019 Apr 29.

PMID:
31036773
12.

Controversies in Allergy: Should Severe Asthma with Eosinophilic Phenotype Always Be Treated with Anti-IL-5 Therapies.

Pavord ID, Hanania NA.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1430-1436. doi: 10.1016/j.jaip.2019.03.010. Epub 2019 Apr 5. Review. No abstract available.

PMID:
30962155
13.

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019.

Singh D, Agusti A, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Criner GJ, Frith P, Halpin DMG, Han M, López Varela MV, Martinez F, Montes de Oca M, Papi A, Pavord ID, Roche N, Sin DD, Stockley R, Vestbo J, Wedzicha JA, Vogelmeier C.

Eur Respir J. 2019 May 18;53(5). pii: 1900164. doi: 10.1183/13993003.00164-2019. Print 2019 May. Review.

PMID:
30846476
14.

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report.

McDonald VM, Fingleton J, Agusti A, Hiles SA, Clark VL, Holland AE, Marks GB, Bardin PP, Beasley R, Pavord ID, Wark PAB, Gibson PG; participants of the Treatable Traits Down Under International Workshop; Treatable Traits Down Under International Workshop participants:.

Eur Respir J. 2019 May 9;53(5). pii: 1802058. doi: 10.1183/13993003.02058-2018. Print 2019 May. Review.

PMID:
30846468
15.

Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function.

Hardman C, Chen W, Luo J, Batty P, Chen YL, Nahler J, Wu Y, Pavord ID, Erpenbeck VJ, Sandham DA, Xue L, Ogg G.

J Allergy Clin Immunol. 2019 Jun;143(6):2329-2333. doi: 10.1016/j.jaci.2019.02.015. Epub 2019 Feb 28. No abstract available.

PMID:
30825466
16.

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment.

Saunders R, Kaul H, Berair R, Gonem S, Singapuri A, Sutcliffe AJ, Chachi L, Biddle MS, Kaur D, Bourne M, Pavord ID, Wardlaw AJ, Siddiqui SH, Kay RA, Brook BS, Smallwood RH, Brightling CE.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaao6451. doi: 10.1126/scitranslmed.aao6451.

PMID:
30760581
17.

Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials. Bridging Clinical and Patient Perspectives.

Siddiqui S, Denlinger LC, Fowler SJ, Akuthota P, Shaw DE, Heaney LG, Brown L, Castro M, Winders TA, Kraft M, Wagers S, Peters MC, Pavord ID, Walker S, Jarjour NN.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):823-829. doi: 10.1164/rccm.201809-1817PP. No abstract available.

PMID:
30726120
18.

Prospective observational study in patients with obstructive lung disease: NOVELTY design.

Reddel HK, Gerhardsson de Verdier M, Agustí A, Anderson G, Beasley R, Bel EH, Janson C, Make B, Martin RJ, Pavord I, Price D, Keen C, Gardev A, Rennard S, Sveréus A, Bansal AT, Brannman L, Karlsson N, Nuevo J, Nyberg F, Young SS, Vestbo J.

ERJ Open Res. 2019 Feb 1;5(1). pii: 00036-2018. doi: 10.1183/23120541.00036-2018. eCollection 2019 Feb.

19.

Inhaled Corticosteroid Therapy in Adult Asthma. Time for a New Therapeutic Dose Terminology.

Beasley R, Harper J, Bird G, Maijers I, Weatherall M, Pavord ID.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1471-1477. doi: 10.1164/rccm.201810-1868CI.

PMID:
30645143
20.

Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST.

McKeever T, Mortimer K, Bradshaw L, Haydock R, Pavord I, Higgins B, Walker S, Wilson A, Price D, Thomas M, Devereux G, Brightling C, Renwick C, Parrott S, Mitchell E, Duley L, Harrison T.

Health Technol Assess. 2018 Dec;22(70):1-82. doi: 10.3310/hta22700.

21.

Correction: Synergistic activation of pro-inflammatory type-2 CD8 + T lymphocytes by lipid mediators in severe eosinophilic asthma.

Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L.

Mucosal Immunol. 2019 Mar;12(2):581. doi: 10.1038/s41385-018-0121-5.

PMID:
30518781
22.

Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids.

Siddiqui SH, Pavord ID, Barnes NC, Guasconi A, Lettis S, Pascoe S, Petruzzelli S.

Int J Chron Obstruct Pulmon Dis. 2018 Nov 6;13:3669-3676. doi: 10.2147/COPD.S179425. eCollection 2018.

23.

Exacerbations of severe asthma in patients treated with mepolizumab.

Shrimanker R, Pavord ID, Yancey S, Heaney LG, Green RH, Bradding P, Hargadon B, Brightling CE, Wardlaw AJ, Haldar P.

Eur Respir J. 2018 Dec 13;52(6). pii: 1801127. doi: 10.1183/13993003.01127-2018. Print 2018 Dec. No abstract available.

PMID:
30464012
24.

Oral corticosteroid-dependent asthma: current knowledge and future needs.

Pavord ID.

Curr Opin Pulm Med. 2019 Jan;25(1):51-58. doi: 10.1097/MCP.0000000000000541.

PMID:
30461530
25.

Current Controversies in Chronic Obstructive Pulmonary Disease. A Report from the Global Initiative for Chronic Obstructive Lung Disease Scientific Committee.

Criner GJ, Martinez FJ, Aaron S, Agusti A, Anzueto A, Bafadhel M, Barnes PJ, Bourbeau J, Chen R, Ewig J, Fabbri LM, Frith P, Halpin DMG, Han M, Montes de Oca M, Nishimura M, O'Donnell D, Papi A, Pavord I, Roche N, Rodriguez-Roisin R, Salvi S, Singh D, Sin DD, Stockley R, López Varela MV, Vestbo J, Vogelmeier CF, Washko G, Wedzicha JA, Celli BR.

Ann Am Thorac Soc. 2019 Jan;16(1):29-39. doi: 10.1513/AnnalsATS.201808-557PS. No abstract available.

PMID:
30427736
26.

Do we really need a new classification of airway diseases?

Agusti A, Pavord ID.

Lancet Respir Med. 2018 Dec;6(12):891-893. doi: 10.1016/S2213-2600(18)30386-2. Epub 2018 Nov 9. No abstract available.

PMID:
30420248
27.

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Nonadherence in Severe Asthma.

Heaney LG, Busby J, Bradding P, Chaudhuri R, Mansur AH, Niven R, Pavord ID, Lindsay JT, Costello RW; Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK).

Am J Respir Crit Care Med. 2019 Feb 15;199(4):454-464. doi: 10.1164/rccm.201806-1182OC.

PMID:
30339770
28.

Association between blood eosinophil count and risk of readmission for patients with asthma: Historical cohort study.

Kerkhof M, Tran TN, van den Berge M, Brusselle GG, Gopalan G, Jones RCM, Kocks JWH, Menzies-Gow A, Nuevo J, Pavord ID, Rastogi S, Price DB.

PLoS One. 2018 Jul 25;13(7):e0201143. doi: 10.1371/journal.pone.0201143. eCollection 2018.

29.

GLUCOLD, eosinophils and chronic obstructive pulmonary disease.

Pavord ID.

Respirology. 2018 Nov;23(11):966-967. doi: 10.1111/resp.13361. Epub 2018 Jun 26. No abstract available.

30.

Will precision medicine become an effective tool for airway disease?

Shrimanker R, Pavord ID.

Per Med. 2018 Jul 1;15(4):243-245. doi: 10.2217/pme-2018-0027. Epub 2018 Jun 21. No abstract available.

PMID:
29927347
31.

Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis.

Psallidas I, Kanellakis NI, Gerry S, Thézénas ML, Charles PD, Samsonova A, Schiller HB, Fischer R, Asciak R, Hallifax RJ, Mercer R, Dobson M, Dong T, Pavord ID, Collins GS, Kessler BM, Pass HI, Maskell N, Stathopoulos GT, Rahman NM.

Lancet Oncol. 2018 Jul;19(7):930-939. doi: 10.1016/S1470-2045(18)30294-8. Epub 2018 Jun 13.

PMID:
29908990
32.

Synergistic activation of pro-inflammatory type-2 CD8+ T lymphocytes by lipid mediators in severe eosinophilic asthma.

Hilvering B, Hinks TSC, Stöger L, Marchi E, Salimi M, Shrimanker R, Liu W, Chen W, Luo J, Go S, Powell T, Cane J, Thulborn S, Kurioka A, Leng T, Matthews J, Connolly C, Borg C, Bafadhel M, Willberg CB, Ramasamy A, Djukanović R, Ogg G, Pavord ID, Klenerman P, Xue L.

Mucosal Immunol. 2018 Sep;11(5):1408-1419. doi: 10.1038/s41385-018-0049-9. Epub 2018 Jun 15. Erratum in: Mucosal Immunol. 2018 Dec 5;:.

33.

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma.

Castro M, Corren J, Pavord ID, Maspero J, Wenzel S, Rabe KF, Busse WW, Ford L, Sher L, FitzGerald JM, Katelaris C, Tohda Y, Zhang B, Staudinger H, Pirozzi G, Amin N, Ruddy M, Akinlade B, Khan A, Chao J, Martincova R, Graham NMH, Hamilton JD, Swanson BN, Stahl N, Yancopoulos GD, Teper A.

N Engl J Med. 2018 Jun 28;378(26):2486-2496. doi: 10.1056/NEJMoa1804092. Epub 2018 May 21.

34.

Biologics and chronic obstructive pulmonary disease.

Pavord ID.

J Allergy Clin Immunol. 2018 Jun;141(6):1983-1991. doi: 10.1016/j.jaci.2018.04.020. Epub 2018 May 4. Review.

PMID:
29729941
35.

Liberty Asthma QUEST: Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate Dupilumab Efficacy/Safety in Patients with Uncontrolled, Moderate-to-Severe Asthma.

Busse WW, Maspero JF, Rabe KF, Papi A, Wenzel SE, Ford LB, Pavord ID, Zhang B, Staudinger H, Pirozzi G, Amin N, Akinlade B, Eckert L, Chao J, Graham NMH, Teper A.

Adv Ther. 2018 May;35(5):737-748. doi: 10.1007/s12325-018-0702-4. Epub 2018 May 3.

36.

Blood eosinophil levels as a biomarker in COPD.

Brusselle G, Pavord ID, Landis S, Pascoe S, Lettis S, Morjaria N, Barnes N, Hilton E.

Respir Med. 2018 May;138:21-31. doi: 10.1016/j.rmed.2018.03.016. Epub 2018 Mar 15. Review.

PMID:
29724389
37.

Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.

Ghebre MA, Pang PH, Diver S, Desai D, Bafadhel M, Haldar K, Kebadze T, Cohen S, Newbold P, Rapley L, Woods J, Rugman P, Pavord ID, Johnston SL, Barer M, May RD, Brightling CE.

J Allergy Clin Immunol. 2018 Jun;141(6):2027-2036.e12. doi: 10.1016/j.jaci.2018.04.013. Epub 2018 Apr 28.

38.

The association between blood eosinophils and risk and treatment outcome in COPD is not dichotomised.

Pascoe S, Pavord I, Hinds D, Locantore N, Barnes N.

Lancet Respir Med. 2018 May;6(5):e18. doi: 10.1016/S2213-2600(18)30137-1. Epub 2018 Apr 5. No abstract available.

PMID:
29627194
39.

Associations between blood eosinophils and decline in lung function among adults with and without asthma.

Hancox RJ, Pavord ID, Sears MR.

Eur Respir J. 2018 Apr 19;51(4). pii: 1702536. doi: 10.1183/13993003.02536-2017. Print 2018 Apr.

PMID:
29563173
40.

Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations.

McKeever T, Mortimer K, Wilson A, Walker S, Brightling C, Skeggs A, Pavord I, Price D, Duley L, Thomas M, Bradshaw L, Higgins B, Haydock R, Mitchell E, Devereux G, Harrison T.

N Engl J Med. 2018 Mar 8;378(10):902-910. doi: 10.1056/NEJMoa1714257. Epub 2018 Mar 3.

41.

Mepolizumab for Eosinophilic COPD.

Sciurba FC, Bradford ES, Pavord ID.

N Engl J Med. 2018 Feb 15;378(7):681-683. doi: 10.1056/NEJMc1715454. No abstract available.

PMID:
29443666
42.

A retrospective cohort study in severe asthma describing commonly measured biomarkers: Eosinophil count and IgE levels.

Haughney J, Morice A, Blyth KG, Lee AJ, Coutts A, McKnight E, Pavord I.

Respir Med. 2018 Jan;134:117-123. doi: 10.1016/j.rmed.2017.12.001. Epub 2017 Dec 5.

PMID:
29413497
43.

COUNTERPOINT: Should an Attempt Be Made to Withdraw Inhaled Corticosteroids in All Patients With Stable GOLD 3 (30% ≤ FEV1 < 50% Predicted) COPD? No.

Pavord ID.

Chest. 2018 Apr;153(4):782-784. doi: 10.1016/j.chest.2018.01.030. Epub 2018 Feb 2. No abstract available.

PMID:
29410364
44.

Rebuttal From Dr Pavord.

Pavord ID.

Chest. 2018 Apr;153(4):786-787. doi: 10.1016/j.chest.2018.01.026. Epub 2018 Feb 2. No abstract available.

PMID:
29410251
45.

'We can't diagnose asthma until <insert arbitrary age>'.

Bush A, Pavord ID.

Arch Dis Child. 2018 Aug;103(8):729-731. doi: 10.1136/archdischild-2017-314180. Epub 2018 Jan 5. No abstract available.

46.

A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.

Hanratty CE, Matthews JG, Arron JR, Choy DF, Pavord ID, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Djukanovic R, Gallagher N, Fowler SJ, Hardman TC, Harrison T, Holweg CT, Howarth PH, Lordan J, Mansur AH, Menzies-Gow A, Mosesova S, Niven RM, Robinson DS, Shaw DE, Walker S, Woodcock A, Heaney LG; RASP-UK (Refractory Asthma Stratification Programme) Consortium.

Trials. 2018 Jan 4;19(1):5. doi: 10.1186/s13063-017-2384-7.

47.

Evaluation of Potential Continuation Rules for Mepolizumab Treatment of Severe Eosinophilic Asthma.

Gunsoy NB, Cockle SM, Yancey SW, Keene ON, Bradford ES, Albers FC, Pavord ID.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):874-882.e4. doi: 10.1016/j.jaip.2017.11.026. Epub 2017 Dec 16.

48.

Physiotherapy breathing retraining for asthma: a randomised controlled trial.

Bruton A, Lee A, Yardley L, Raftery J, Arden-Close E, Kirby S, Zhu S, Thiruvothiyur M, Webley F, Taylor L, Gibson D, Yao G, Stafford-Watson M, Versnel J, Moore M, George S, Little P, Djukanovic R, Price D, Pavord ID, Holgate ST, Thomas M.

Lancet Respir Med. 2018 Jan;6(1):19-28. doi: 10.1016/S2213-2600(17)30474-5. Epub 2017 Dec 14.

49.

Biomarkers for severe eosinophilic asthma.

Yancey SW, Keene ON, Albers FC, Ortega H, Bates S, Bleecker ER, Pavord I.

J Allergy Clin Immunol. 2017 Dec;140(6):1509-1518. doi: 10.1016/j.jaci.2017.10.005. Review.

50.

Author Correction: The impact of poor asthma control among asthma patients treated with inhaled corticosteroids plus long-acting β2-agonists in the United Kingdom: a cross-sectional analysis.

Pavord ID, Mathieson N, Scowcroft A, Pedersini R, Isherwood G, Price D.

NPJ Prim Care Respir Med. 2017 Dec 5;27(1):65. doi: 10.1038/s41533-017-0063-5.

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