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A case of idiopathic multicentric Castleman disease in an alemtuzumab-treated patient with MS.

Rolfes L, Pfeuffer S, Ruck T, Windhagen S, Oschlies I, Pavenstädt HJ, Angenendt L, Wiendl H, Krämer J, Meuth SG.

Neurol Neuroimmunol Neuroinflamm. 2019 Nov 8;7(1). pii: e638. doi: 10.1212/NXI.0000000000000638. Print 2020 Jan. No abstract available. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2019 Dec 5;7(1):.


Correction: Fast Tac Metabolizers at Risk-It is Time for a C/D Ratio Calculation. J. Clin. Med. 2019, 8, 587.

Schütte-Nütgen K, Thölking G, Steinke J, Pavenstädt H, Schmidt R, Suwelack B, Reuter S.

J Clin Med. 2019 Nov 4;8(11). pii: E1870. doi: 10.3390/jcm8111870.


Protein Abundance of Clinically Relevant Drug Transporters in The Human Kidneys.

Oswald S, Müller J, Neugebauer U, Schröter R, Herrmann E, Pavenstädt H, Ciarimboli G.

Int J Mol Sci. 2019 Oct 24;20(21). pii: E5303. doi: 10.3390/ijms20215303.


A Low Tacrolimus Concentration/Dose Ratio Increases the Risk for the Development of Acute Calcineurin Inhibitor-Induced Nephrotoxicity.

Thölking G, Schütte-Nütgen K, Schmitz J, Rovas A, Dahmen M, Bautz J, Jehn U, Pavenstädt H, Heitplatz B, Van Marck V, Suwelack B, Reuter S.

J Clin Med. 2019 Oct 2;8(10). pii: E1586. doi: 10.3390/jcm8101586.


Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.

Drost CC, Rovas A, Kusche-Vihrog K, Van Slyke P, Kim H, Hoang VC, Maynes JT, Wennmann DO, Pavenstädt H, Linke W, Lukasz A, Hesse B, Kümpers P.

Thromb Haemost. 2019 Nov;119(11):1827-1838. doi: 10.1055/s-0039-1695768. Epub 2019 Sep 7.


An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection.

Hucke A, Rinschen MM, Bauer OB, Sperling M, Karst U, Köppen C, Sommer K, Schröter R, Ceresa C, Chiorazzi A, Canta A, Semperboni S, Marmiroli P, Cavaletti G, Schlatt S, Schlatter E, Pavenstädt H, Heitplatz B, Van Marck V, Sparreboom A, Barz V, Knief A, Deuster D, Zehnhoff-Dinnesen AA, Ciarimboli G.

Arch Toxicol. 2019 Oct;93(10):2835-2848. doi: 10.1007/s00204-019-02557-9. Epub 2019 Sep 6.


Validation of the Kidney Donor Profile Index (KDPI) to assess a deceased donor's kidneys' outcome in a European cohort.

Dahmen M, Becker F, Pavenstädt H, Suwelack B, Schütte-Nütgen K, Reuter S.

Sci Rep. 2019 Aug 2;9(1):11234. doi: 10.1038/s41598-019-47772-7.


Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis.

Rovas A, Seidel LM, Vink H, Pohlkötter T, Pavenstädt H, Ertmer C, Hessler M, Kümpers P.

Crit Care. 2019 Jul 24;23(1):260. doi: 10.1186/s13054-019-2542-2.


Phenotypic and Genotypic Characterization of Escherichia coli Causing Urinary Tract Infections in Kidney-Transplanted Patients.

Abo Basha J, Kiel M, Görlich D, Schütte-Nütgen K, Witten A, Pavenstädt H, Kahl BC, Dobrindt U, Reuter S.

J Clin Med. 2019 Jul 7;8(7). pii: E988. doi: 10.3390/jcm8070988.


Nephrin Signaling Results in Integrin β1 Activation.

Dlugos CP, Picciotto C, Lepa C, Krakow M, Stöber A, Eddy ML, Weide T, Jeibmann A, P Krahn M, Van Marck V, Klingauf J, Ricker A, Wedlich-Söldner R, Pavenstädt H, Klämbt C, George B.

J Am Soc Nephrol. 2019 Jun;30(6):1006-1019. doi: 10.1681/ASN.2018040362. Epub 2019 May 16.


Fast Tac Metabolizers at Risk ⁻ It is Time for a C/D Ratio Calculation.

Schütte-Nütgen K, Thölking G, Steinke J, Pavenstädt H, Schmidt R, Suwelack B, Reuter S.

J Clin Med. 2019 Apr 28;8(5). pii: E587. doi: 10.3390/jcm8050587. Erratum in: J Clin Med. 2019 Nov 04;8(11):.


Expanding the donor pool in kidney transplantation: Should organs with acute kidney injury be accepted?-A retrospective study.

Schütte-Nütgen K, Finke M, Ehlert S, Thölking G, Pavenstädt H, Suwelack B, Palmes D, Bahde R, Koch R, Reuter S.

PLoS One. 2019 Mar 13;14(3):e0213608. doi: 10.1371/journal.pone.0213608. eCollection 2019.


Increased soluble fms-like tyrosine kinase 1 after ischemia reperfusion contributes to adverse clinical outcomes following kidney transplantation.

Wewers TM, Mayer AB, Pfleiderer A, Beul K, Schmidt R, Heitplatz B, Van Marck V, Nolte I, Pavenstädt H, Reuter S, Brand M, Di Marco GS.

Kidney Int. 2019 May;95(5):1091-1102. doi: 10.1016/j.kint.2018.11.023. Epub 2019 Feb 26.


Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease.

Schmitz B, Kleber ME, Lenders M, Delgado GE, Engelbertz C, Huang J, Pavenstädt H, Breithardt G, Brand SM, März W, Brand E.

Sci Rep. 2019 Feb 26;9(1):2750. doi: 10.1038/s41598-019-39055-y.


[Response of dermatomyositis with lung involvement to Janus kinase inhibitor treatment].

Hornig J, Weinhage T, Schmidt LH, Buerke B, Schneider U, Pavenstädt H, Becker H, Gabriëls G.

Z Rheumatol. 2018 Dec;77(10):952-957. doi: 10.1007/s00393-018-0565-8. German.


Notch Signaling Activity Determines Uptake and Biological Effect of Imatinib in Systemic Sclerosis Dermal Fibroblasts.

Harrach S, Barz V, Pap T, Pavenstädt H, Schlatter E, Edemir B, Distler J, Ciarimboli G, Bertrand J.

J Invest Dermatol. 2019 Feb;139(2):439-447. doi: 10.1016/j.jid.2018.08.021. Epub 2018 Sep 28.


Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria.

Schenk LK, Buchholz B, Henke SF, Michgehl U, Daniel C, Amann K, Kunzelmann K, Pavenstädt H.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1777-F1786. doi: 10.1152/ajprenal.00638.2017. Epub 2018 Aug 29.


Nuclear YAP localization as a key regulator of podocyte function.

Bonse J, Wennmann DO, Kremerskothen J, Weide T, Michgehl U, Pavenstädt H, Vollenbröker B.

Cell Death Dis. 2018 Aug 28;9(9):850. doi: 10.1038/s41419-018-0878-1.


Nephron-specific knockin of the PIKfyve-binding-deficient Vac14L156R mutant results in albuminuria and mesangial expansion.

Michgehl U, Skryabin BV, Bayraktar S, Vollenbröker B, Ciarimboli G, Heitplatz B, Van Marck V, Gröne HJ, Pavenstädt H, Weide T.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1307-F1319. doi: 10.1152/ajprenal.00191.2018. Epub 2018 Aug 1.


Getting a Notch closer to renal dysfunction: activated Notch suppresses expression of the adaptor protein Disabled-2 in tubular epithelial cells.

Schütte-Nütgen K, Edeling M, Mendl G, Krahn MP, Edemir B, Weide T, Kremerskothen J, Michgehl U, Pavenstädt H.

FASEB J. 2019 Jan;33(1):821-832. doi: 10.1096/fj.201800392RR. Epub 2018 Jul 27.


Regulation and Function of TMEM16F in Renal Podocytes.

Schenk LK, Ousingsawat J, Skryabin BV, Schreiber R, Pavenstädt H, Kunzelmann K.

Int J Mol Sci. 2018 Jun 18;19(6). pii: E1798. doi: 10.3390/ijms19061798.


[Fever and Pulmo-Renal Syndrome with Cholecystitis in a Traveller - a Differential Diagnostic Challenge].

Schenk LK, Pavenstädt H, Kümpers P.

Dtsch Med Wochenschr. 2018 Feb;143(4):263-266. doi: 10.1055/s-0043-122705. Epub 2018 Feb 26. German.


Bedside analysis of the sublingual microvascular glycocalyx in the emergency room and intensive care unit - the GlycoNurse study.

Rovas A, Lukasz AH, Vink H, Urban M, Sackarnd J, Pavenstädt H, Kümpers P.

Scand J Trauma Resusc Emerg Med. 2018 Feb 14;26(1):16. doi: 10.1186/s13049-018-0483-4.


Is there a "weekend effect" in kidney transplantation?

Schütte-Nütgen K, Thölking G, Dahmen M, Becker F, Kebschull L, Schmidt R, Pavenstädt H, Suwelack B, Reuter S.

PLoS One. 2017 Dec 28;12(12):e0190227. doi: 10.1371/journal.pone.0190227. eCollection 2017.


Tropomyosin-related kinase C (TrkC) enhances podocyte migration by ERK-mediated WAVE2 activation.

Gromnitza S, Lepa C, Weide T, Schwab A, Pavenstädt H, George B.

FASEB J. 2018 Mar;32(3):1665-1676. doi: 10.1096/fj.201700703R. Epub 2018 Jan 3.


Male kidney allograft recipients at risk for urinary tract infection?

Thölking G, Schuette-Nuetgen K, Vogl T, Dobrindt U, Kahl BC, Brand M, Pavenstädt H, Suwelack B, Koch R, Reuter S.

PLoS One. 2017 Nov 16;12(11):e0188262. doi: 10.1371/journal.pone.0188262. eCollection 2017.


WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway.

Hermann A, Wennmann DO, Gromnitza S, Edeling M, Van Marck V, Sudol M, Schaefer L, Duning K, Weide T, Pavenstädt H, Kremerskothen J.

Hepatology. 2018 Apr;67(4):1546-1559. doi: 10.1002/hep.29647. Epub 2018 Feb 18.


Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma.

Schelleckes K, Schmitz B, Ciarimboli G, Lenders M, Pavenstädt HJ, Herrmann E, Brand SM, Brand E.

Clin Epigenetics. 2017 Oct 6;9:109. doi: 10.1186/s13148-017-0415-6. eCollection 2017.


Bone marrow-derived cells and their conditioned medium induce microvascular repair in uremic rats by stimulation of endogenous repair mechanisms.

Golle L, Gerth HU, Beul K, Heitplatz B, Barth P, Fobker M, Pavenstädt H, Di Marco GS, Brand M.

Sci Rep. 2017 Aug 25;7(1):9444. doi: 10.1038/s41598-017-09883-x.


Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes.

Schenk LK, Möller-Kerutt A, Klosowski R, Wolters D, Schaffner-Reckinger E, Weide T, Pavenstädt H, Vollenbröker B.

FASEB J. 2017 Nov;31(11):5019-5035. doi: 10.1096/fj.201700142R. Epub 2017 Aug 2.


Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes.

Hochapfel F, Denk L, Mendl G, Schulze U, Maaßen C, Zaytseva Y, Pavenstädt H, Weide T, Rachel R, Witzgall R, Krahn MP.

Cell Mol Life Sci. 2017 Dec;74(24):4573-4586. doi: 10.1007/s00018-017-2593-y. Epub 2017 Jul 17.


GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection.

Kentrup D, Bovenkamp P, Busch A, Schuette-Nuetgen K, Pawelski H, Pavenstädt H, Schlatter E, Herrmann KH, Reichenbach JR, Löffler B, Heitplatz B, Van Marck V, Yadav NN, Liu G, van Zijl PCM, Reuter S, Hoerr V.

Kidney Int. 2017 Sep;92(3):757-764. doi: 10.1016/j.kint.2017.04.015. Epub 2017 Jul 12.


Intracellular APOL1 Risk Variants Cause Cytotoxicity Accompanied by Energy Depletion.

Granado D, Müller D, Krausel V, Kruzel-Davila E, Schuberth C, Eschborn M, Wedlich-Söldner R, Skorecki K, Pavenstädt H, Michgehl U, Weide T.

J Am Soc Nephrol. 2017 Nov;28(11):3227-3238. doi: 10.1681/ASN.2016111220. Epub 2017 Jul 10.


Molecular Adsorbent Recirculating System Can Reduce Short-Term Mortality Among Patients With Acute-on-Chronic Liver Failure-A Retrospective Analysis.

Gerth HU, Pohlen M, Thölking G, Pavenstädt H, Brand M, Hüsing-Kabar A, Wilms C, Maschmeier M, Kabar I, Torner J, Pavesi M, Arroyo V, Banares R, Schmidt HHJ.

Crit Care Med. 2017 Oct;45(10):1616-1624. doi: 10.1097/CCM.0000000000002562.


Cross talk between the Crumbs complex and Hippo signaling in renal epithelial cells.

Michgehl U, Pavenstädt H, Vollenbröker B.

Pflugers Arch. 2017 Aug;469(7-8):917-926. doi: 10.1007/s00424-017-2004-0. Epub 2017 Jun 13. Review.


Two-year outcome and risk factors for mortality in patients with coronary artery disease and renal failure: The prospective, observational CAD-REF Registry.

Engelbertz C, Reinecke H, Breithardt G, Schmieder RE, Fobker M, Fischer D, Schmitz B, Pinnschmidt HO, Wegscheider K, Pavenstädt H, Brand E.

Int J Cardiol. 2017 Sep 15;243:65-72. doi: 10.1016/j.ijcard.2017.05.022. Epub 2017 May 7.


Hyponatremia upon presentation to the emergency department - the need for urgent neuroimaging studies.

Bokemeyer A, Dziewas R, Wiendl H, Schwindt W, Bicsán P, Kümpers P, Pavenstädt H.

Sci Rep. 2017 May 16;7(1):1953. doi: 10.1038/s41598-017-02030-6.


Endothelial glycocalyx breakdown is mediated by angiopoietin-2.

Lukasz A, Hillgruber C, Oberleithner H, Kusche-Vihrog K, Pavenstädt H, Rovas A, Hesse B, Goerge T, Kümpers P.

Cardiovasc Res. 2017 May 1;113(6):671-680. doi: 10.1093/cvr/cvx023.


Molecular adsorbent recirculating system (MARS) in acute liver injury and graft dysfunction: Results from a case-control study.

Gerth HU, Pohlen M, Thölking G, Pavenstädt H, Brand M, Wilms C, Hüsing-Kabar A, Görlich D, Kabar I, Schmidt HH.

PLoS One. 2017 Apr 12;12(4):e0175529. doi: 10.1371/journal.pone.0175529. eCollection 2017.


Sepsis recognition in the emergency department - impact on quality of care and outcome?

Morr M, Lukasz A, Rübig E, Pavenstädt H, Kümpers P.

BMC Emerg Med. 2017 Mar 23;17(1):11. doi: 10.1186/s12873-017-0122-9.


[Extracorporeal liver support of liver failure].

Gerth HU, Pohlen M, Pavenstädt H, Schmidt H.

Z Gastroenterol. 2017 Apr;55(4):383-393. doi: 10.1055/s-0043-100020. Epub 2017 Mar 14. Review. German.


Structural cartilage damage attracts circulating rheumatoid arthritis synovial fibroblasts into affected joints.

Hillen J, Geyer C, Heitzmann M, Beckmann D, Krause A, Winkler I, Pavenstädt H, Bremer C, Pap T, Korb-Pap A.

Arthritis Res Ther. 2017 Feb 28;19(1):40. doi: 10.1186/s13075-017-1245-9.


Cellular vacuolization caused by overexpression of the PIKfyve-binding deficient Vac14L156R is rescued by starvation and inhibition of vacuolar-ATPase.

Schulze U, Vollenbröker B, Kühnl A, Granado D, Bayraktar S, Rescher U, Pavenstädt H, Weide T.

Biochim Biophys Acta Mol Cell Res. 2017 May;1864(5):749-759. doi: 10.1016/j.bbamcr.2017.02.012. Epub 2017 Feb 16.


Differential effects of anoctamins on intracellular calcium signals.

Cabrita I, Benedetto R, Fonseca A, Wanitchakool P, Sirianant L, Skryabin BV, Schenk LK, Pavenstädt H, Schreiber R, Kunzelmann K.

FASEB J. 2017 May;31(5):2123-2134. doi: 10.1096/fj.201600797RR. Epub 2017 Feb 9.


Pals1 Haploinsufficiency Results in Proteinuria and Cyst Formation.

Weide T, Vollenbröker B, Schulze U, Djuric I, Edeling M, Bonse J, Hochapfel F, Panichkina O, Wennmann DO, George B, Kim S, Daniel C, Seggewiß J, Amann K, Kriz W, Krahn MP, Pavenstädt H.

J Am Soc Nephrol. 2017 Jul;28(7):2093-2107. doi: 10.1681/ASN.2016040474. Epub 2017 Feb 2.


Tetraspanin CD63 controls basolateral sorting of organic cation transporter 2 in renal proximal tubules.

Schulze U, Brast S, Grabner A, Albiker C, Snieder B, Holle S, Schlatter E, Schröter R, Pavenstädt H, Herrmann E, Lambert C, Spoden GA, Florin L, Saftig P, Ciarimboli G.

FASEB J. 2017 Apr;31(4):1421-1433. doi: 10.1096/fj.201600901R. Epub 2016 Dec 28.


Calcium-mediated actin reset (CaAR) mediates acute cell adaptations.

Wales P, Schuberth CE, Aufschnaiter R, Fels J, García-Aguilar I, Janning A, Dlugos CP, Schäfer-Herte M, Klingner C, Wälte M, Kuhlmann J, Menis E, Hockaday Kang L, Maier KC, Hou W, Russo A, Higgs HN, Pavenstädt H, Vogl T, Roth J, Qualmann B, Kessels MM, Martin DE, Mulder B, Wedlich-Söldner R.

Elife. 2016 Dec 6;5. pii: e19850. doi: 10.7554/eLife.19850.


A Comparison of Different Algorithms for the Assessment of Cardiovascular Risk in Patients at Waiting List for Kidney Transplantation.

Reuter S, Reiermann S, Malyar V, Schütte-Nütgen K, Schmidt R, Pavenstädt H, Reinecke H, Suwelack B.

PLoS One. 2016 Oct 21;11(10):e0161927. doi: 10.1371/journal.pone.0161927. eCollection 2016.


MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients.

Harrach S, Schmidt-Lauber C, Pap T, Pavenstädt H, Schlatter E, Schmidt E, Berdel WE, Schulze U, Edemir B, Jeromin S, Haferlach T, Ciarimboli G, Bertrand J.

Blood Cancer J. 2016 Sep 16;6:e470. doi: 10.1038/bcj.2016.79.


Influence of tacrolimus metabolism rate on BKV infection after kidney transplantation.

Thölking G, Schmidt C, Koch R, Schuette-Nuetgen K, Pabst D, Wolters H, Kabar I, Hüsing A, Pavenstädt H, Reuter S, Suwelack B.

Sci Rep. 2016 Aug 30;6:32273. doi: 10.1038/srep32273.

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