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Items: 1 to 50 of 141


Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor.

Liu X, Palaniyandi S, Zhu I, Tang J, Li W, Wu X, Ochsner SP, Pauza CD, Cohen JI, Zhu X.

Nat Commun. 2019 Jul 9;10(1):3020. doi: 10.1038/s41467-019-10865-y.


Persistent gamma delta T-cell dysfunction in chronic HCV infection despite direct-acting antiviral therapy induced cure.

Ghosh A, Mondal RK, Romani S, Bagchi S, Cairo C, Pauza CD, Kottilil S, Poonia B.

J Viral Hepat. 2019 Sep;26(9):1105-1116. doi: 10.1111/jvh.13121. Epub 2019 May 26.


Gamma Delta T Cell Therapy for Cancer: It Is Good to be Local.

Pauza CD, Liou ML, Lahusen T, Xiao L, Lapidus RG, Cairo C, Li H.

Front Immunol. 2018 Jun 8;9:1305. doi: 10.3389/fimmu.2018.01305. eCollection 2018. Review.


Factors associated with high cardiovascular risk in a primarily African American, urban HIV-infected population.

Bagchi S, Burrowes SA, Fantry LE, Hossain MB, Tollera GH, Kottilil S, Pauza CD, Miller M, Baumgarten M, Redfield RR.

SAGE Open Med. 2017 Aug 10;5:2050312117725644. doi: 10.1177/2050312117725644. eCollection 2017.


Cancer Diagnostic and Predictive Biomarkers 2016.

Buonaguro FM, Pauza CD, Tornesello ML, Hainaut P, Franco R, Tommasino M.

Biomed Res Int. 2017;2017:7362721. doi: 10.1155/2017/7362721. Epub 2017 Jun 18. No abstract available.


An HIV Envelope gp120-Fc Fusion Protein Elicits Effector Antibody Responses in Rhesus Macaques.

Shubin Z, Li W, Poonia B, Ferrari G, LaBranche C, Montefiori D, Zhu X, Pauza CD.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00028-17. doi: 10.1128/CVI.00028-17. Print 2017 Jun.


Interleukin-18 activates Vγ9Vδ2+ T cells from HIV-positive individuals: recovering the response to phosphoantigen.

Murday AS, Chaudhry S, Pauza CD.

Immunology. 2017 Aug;151(4):385-394. doi: 10.1111/imm.12735. Epub 2017 May 24.


Prolonged PD1 Expression on Neonatal Vδ2 Lymphocytes Dampens Proinflammatory Responses: Role of Epigenetic Regulation.

Hsu H, Boudova S, Mvula G, Divala TH, Mungwira RG, Harman C, Laufer MK, Pauza CD, Cairo C.

J Immunol. 2016 Sep 1;197(5):1884-92. doi: 10.4049/jimmunol.1600284. Epub 2016 Jul 29.


Cancer Diagnostic and Predictive Biomarkers 2015.

Buonaguro FM, Pauza CD, Tornesello ML, Hainaut P, Franco R.

Biomed Res Int. 2015;2015:235985. doi: 10.1155/2015/235985. Epub 2015 Oct 12. No abstract available.


Modulation of SIV and HIV DNA vaccine immunity by Fas-FasL signaling.

Yan J, Zapata JC, Pauza CD, Salvato MS.

Viruses. 2015 Mar 23;7(3):1429-53. doi: 10.3390/v7031429.


Evolution and function of the TCR Vgamma9 chain repertoire: It's good to be public.

Pauza CD, Cairo C.

Cell Immunol. 2015 Jul;296(1):22-30. doi: 10.1016/j.cellimm.2015.02.010. Epub 2015 Mar 4. Review.


γδ T Cells in HIV Disease: Past, Present, and Future.

Pauza CD, Poonia B, Li H, Cairo C, Chaudhry S.

Front Immunol. 2015 Jan 30;5:687. doi: 10.3389/fimmu.2014.00687. eCollection 2014. Review.


CD25(+) Bcl6(low) T follicular helper cells provide help to maturing B cells in germinal centers of human tonsil.

Li H, Pauza CD.

Eur J Immunol. 2015 Jan;45(1):298-308. doi: 10.1002/eji.201444911. Epub 2014 Oct 27.


Vγ2Vδ2 T cell Costimulation Increases NK cell Killing of Monocyte-derived Dendritic Cells.

Cairo C, Surendran N, Harris KM, Mazan-Mamczarz K, Sakoda Y, Diaz-Mendez F, Tamada K, Gartenhaus RB, Mann DL, Pauza CD.

Immunology. 2014 Sep 16. doi: 10.1111/imm.12386. [Epub ahead of print]


Levels of CD56+TIM-3- effector CD8 T cells distinguish HIV natural virus suppressors from patients receiving antiretroviral therapy.

Poonia B, Pauza CD.

PLoS One. 2014 Feb 10;9(2):e88884. doi: 10.1371/journal.pone.0088884. eCollection 2014.


Cord blood Vγ2Vδ2 T cells provide a molecular marker for the influence of pregnancy-associated malaria on neonatal immunity.

Cairo C, Longinaker N, Cappelli G, Leke RG, Ondo MM, Djokam R, Fogako J, Leke RJ, Sagnia B, Sosso S, Colizzi V, Pauza CD.

J Infect Dis. 2014 May 15;209(10):1653-62. doi: 10.1093/infdis/jit802. Epub 2013 Dec 10.


Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells.

Li H, Pauza CD.

Retrovirology. 2013 Jun 6;10:60. doi: 10.1186/1742-4690-10-60.


The γδ T-cell receptor repertoire is reconstituted in HIV patients after prolonged antiretroviral therapy.

Chaudhry S, Cairo C, Venturi V, Pauza CD.

AIDS. 2013 Jun 19;27(10):1557-62. doi: 10.1097/QAD.0b013e3283611888.


An attenuated Lassa vaccine in SIV-infected rhesus macaques does not persist or cause arenavirus disease but does elicit Lassa virus-specific immunity.

Zapata JC, Poonia B, Bryant J, Davis H, Ateh E, George L, Crasta O, Zhang Y, Slezak T, Jaing C, Pauza CD, Goicochea M, Moshkoff D, Lukashevich IS, Salvato MS.

Virol J. 2013 Feb 12;10:52. doi: 10.1186/1743-422X-10-52.


High cancer-related mortality in an urban, predominantly African-American, HIV-infected population.

Riedel DJ, Mwangi EI, Fantry LE, Alexander C, Hossain MB, Pauza CD, Redfield RR, Gilliam BL.

AIDS. 2013 Apr 24;27(7):1109-17. doi: 10.1097/QAD.0b013e32835dc068.


Depletion and dysfunction of Vγ2Vδ2 T cells in HIV disease: mechanisms, impacts and therapeutic implications.

Li H, Chaudhry S, Poonia B, Shao Y, Pauza CD.

Cell Mol Immunol. 2013 Jan;10(1):42-9. doi: 10.1038/cmi.2012.50. Epub 2012 Dec 17. Review. Erratum in: Cell Mol Immunol. 2013 May;10(3):283. Chaudry, Suchita [corrected to Chaudhry, Suchita].


Human cord blood γδ T cells expressing public Vγ2 chains dominate the response to bisphosphonate plus interleukin-15.

Cairo C, Sagnia B, Cappelli G, Colizzi V, Leke RG, Leke RJ, Pauza CD.

Immunology. 2013 Apr;138(4):346-60. doi: 10.1111/imm.12039.


The α4β7 integrin binds HIV envelope but does not mediate bystander killing of γδ T cells.

Li H, Pauza CD.

Blood. 2012 Jul 19;120(3):698-9. doi: 10.1182/blood-2012-03-420117. No abstract available.


Impact of persistent HIV replication on CD4 negative Vγ2Vδ2 T cells.

Boudová S, Li H, Sajadi MM, Redfield RR, Pauza CD.

J Infect Dis. 2012 May 1;205(9):1448-55. doi: 10.1093/infdis/jis217. Epub 2012 Mar 26.


Gamma delta T cells from HIV+ donors can be expanded in vitro by zoledronate/interleukin-2 to become cytotoxic effectors for antibody-dependent cellular cytotoxicity.

Poonia B, Pauza CD.

Cytotherapy. 2012 Feb;14(2):173-81. doi: 10.3109/14653249.2011.623693. Epub 2011 Oct 27.


HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDS.

Li H, Pauza CD.

Blood. 2011 Nov 24;118(22):5824-31. doi: 10.1182/blood-2011-05-356535. Epub 2011 Sep 16.


A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection.

Lu L, Palaniyandi S, Zeng R, Bai Y, Liu X, Wang Y, Pauza CD, Roopenian DC, Zhu X.

J Virol. 2011 Oct;85(20):10542-53. doi: 10.1128/JVI.05441-11. Epub 2011 Aug 17.


Lymphocytic choriomeningitis virus (LCMV) infection of macaques: a model for Lassa fever.

Zapata JC, Pauza CD, Djavani MM, Rodas JD, Moshkoff D, Bryant J, Ateh E, Garcia C, Lukashevich IS, Salvato MS.

Antiviral Res. 2011 Nov;92(2):125-38. doi: 10.1016/j.antiviral.2011.07.015. Epub 2011 Jul 27. Review.


Targeting γδ T cells for immunotherapy of HIV disease.

Pauza CD, Riedel DJ, Gilliam BL, Redfield RR.

Future Virol. 2011 Jan 1;6(1):73-84.


High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.

Poonia B, Kijak GH, Pauza CD.

PLoS One. 2010 Dec 20;5(12):e15562. doi: 10.1371/journal.pone.0015562.


Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro.

Li H, Pauza CD.

Cancer Immunol Immunother. 2011 Mar;60(3):361-70. doi: 10.1007/s00262-010-0945-7. Epub 2010 Nov 25.


Impact of age, gender, and race on circulating γδ T cells.

Cairo C, Armstrong CL, Cummings JS, Deetz CO, Tan M, Lu C, Davis CE, Pauza CD.

Hum Immunol. 2010 Oct;71(10):968-75. doi: 10.1016/j.humimm.2010.06.014. Epub 2010 Jun 30.


Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement.

Maniar A, Zhang X, Lin W, Gastman BR, Pauza CD, Strome SE, Chapoval AI.

Blood. 2010 Sep 9;116(10):1726-33. doi: 10.1182/blood-2009-07-234211. Epub 2010 Jun 2.


Repertoire development and the control of cytotoxic/effector function in human gammadelta T cells.

Urban EM, Chapoval AI, Pauza CD.

Clin Dev Immunol. 2010;2010:732893. doi: 10.1155/2010/732893. Epub 2010 Apr 13. Review.


Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.

Li H, Pauza CD.

PLoS One. 2009 Nov 4;4(11):e7726. doi: 10.1371/journal.pone.0007726.


Role of the Fas/FasL pathway in HIV or SIV disease.

Poonia B, Pauza CD, Salvato MS.

Retrovirology. 2009 Oct 15;6:91. doi: 10.1186/1742-4690-6-91. Review.


Control of CD56 expression and tumor cell cytotoxicity in human Vgamma2Vdelta2 T cells.

Urban EM, Li H, Armstrong C, Focaccetti C, Cairo C, Pauza CD.

BMC Immunol. 2009 Sep 21;10:50. doi: 10.1186/1471-2172-10-50.


Circulating natural killer and gammadelta T cells decrease soon after infection of rhesus macaques with lymphocytic choriomeningitis virus.

Rodas JD, Cairo C, Djavani M, Zapata JC, Ruckwardt T, Bryant J, Pauza CD, Lukashevich IS, Salvato MS.

Mem Inst Oswaldo Cruz. 2009 Jul;104(4):583-91.


Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cells.

Riedel DJ, Sajadi MM, Armstrong CL, Cummings JS, Cairo C, Redfield RR, Pauza CD.

AIDS. 2009 Sep 24;23(15):1955-64. doi: 10.1097/QAD.0b013e32832ff1ff.


Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus.

Poonia B, Salvato MS, Yagita H, Maeda T, Okumura K, Pauza CD.

Blood. 2009 Aug 6;114(6):1196-204. doi: 10.1182/blood-2009-02-202655. Epub 2009 Jun 4.


TNF-alpha is a positive regulatory factor for human Vgamma2 Vdelta2 T cells.

Li H, Luo K, Pauza CD.

J Immunol. 2008 Nov 15;181(10):7131-7.


Failure to restore the Vgamma2-Jgamma1.2 repertoire in HIV-infected men receiving highly active antiretroviral therapy (HAART).

Hebbeler AM, Propp N, Cairo C, Li H, Cummings JS, Jacobson LP, Margolick JB, Pauza CD.

Clin Immunol. 2008 Sep;128(3):349-57. doi: 10.1016/j.clim.2008.04.008. Epub 2008 Jul 7.


Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma.

Alexander AA, Maniar A, Cummings JS, Hebbeler AM, Schulze DH, Gastman BR, Pauza CD, Strome SE, Chapoval AI.

Clin Cancer Res. 2008 Jul 1;14(13):4232-40. doi: 10.1158/1078-0432.CCR-07-4912.


Impacts of HIV infection on Vgamma2Vdelta2 T cell phenotype and function: a mechanism for reduced tumor immunity in AIDS.

Cummings JS, Cairo C, Armstrong C, Davis CE, Pauza CD.

J Leukoc Biol. 2008 Aug;84(2):371-9. doi: 10.1189/jlb.1207847. Epub 2008 May 21.


Altered cord blood gammadelta T cell repertoire in Nigeria: possible impacts of environmental factors on neonatal immunity.

Cairo C, Propp N, Auricchio G, Armstrong CL, Abimiku A, Mancino G, Colizzi V, Blattner W, Pauza CD.

Mol Immunol. 2008 Jun;45(11):3190-7. doi: 10.1016/j.molimm.2008.02.029. Epub 2008 Apr 28.


Association between Vgamma2Vdelta2 T cells and disease progression after infection with closely related strains of HIV in China.

Li H, Peng H, Ma P, Ruan Y, Su B, Ding X, Xu C, Pauza CD, Shao Y.

Clin Infect Dis. 2008 May 1;46(9):1466-72. doi: 10.1086/587107.


Attenuated disease in SIV-infected macaques treated with a monoclonal antibody against FasL.

Salvato MS, Yin CC, Yagita H, Maeda T, Okumura K, Tikhonov I, Pauza CD.

Clin Dev Immunol. 2007;2007:93462. doi: 10.1155/2007/93462.


Vdelta2 T-lymphocyte responses in cord blood samples from Italy and Côte d'Ivoire.

Cairo C, Mancino G, Cappelli G, Pauza CD, Galli E, Brunetti E, Colizzi V.

Immunology. 2008 Jul;124(3):380-7. doi: 10.1111/j.1365-2567.2007.02784.x. Epub 2008 Jan 11.


Rapamycin reduces CCR5 mRNA levels in macaques: potential applications in HIV-1 prevention and treatment.

Gilliam BL, Heredia A, Devico A, Le N, Bamba D, Bryant JL, Pauza CD, Redfield RR.

AIDS. 2007 Oct 1;21(15):2108-10.


Early blood profiles of virus infection in a monkey model for Lassa fever.

Djavani MM, Crasta OR, Zapata JC, Fei Z, Folkerts O, Sobral B, Swindells M, Bryant J, Davis H, Pauza CD, Lukashevich IS, Hammamieh R, Jett M, Salvato MS.

J Virol. 2007 Aug;81(15):7960-73. Epub 2007 May 23.

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