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Items: 1 to 50 of 123

1.

Transferability of health cost evaluation across locations in oncology: cluster and principal component analysis as an explorative tool.

Perrier L, Buja A, Mastrangelo G, Baron PS, Ducimetière F, Pauwels PJ, Rossi CR, Gilly FN, Martin A, Favier B, Farsi F, Laramas M, Baldo V, Collard O, Cellier D, Blay JY, Ray-Coquard I.

BMC Health Serv Res. 2014 Nov 18;14:537. doi: 10.1186/s12913-014-0537-x.

2.

7th cancer scientific forum of theCancéropôle Lyon Auvergne Rhône-Alpes: March 20-21, 2012, Lyon, France.

Pauwels PJ, Dumontet C, Reichert JM, Beck A, Goetsch L, Corvaia N, Klein C, Coiffier B, Teicher B.

MAbs. 2012 Jul-Aug;4(4):434-44. doi: 10.4161/mabs.20869. Epub 2012 Jul 1.

3.

E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.

Kendall I, Slotten HA, Codony X, Burgueño J, Pauwels PJ, Vela JM, Fone KC.

Psychopharmacology (Berl). 2011 Feb;213(2-3):413-30. doi: 10.1007/s00213-010-1854-3. Epub 2010 Apr 20.

PMID:
20405281
4.

Reanalysis of constitutively active rat and human 5-HT7(a) receptors in HEK-293F cells demonstrates lack of silent properties for reported neutral antagonists.

Romero G, Pujol M, Pauwels PJ.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Oct;374(1):31-9. Epub 2006 Sep 12.

PMID:
16967291
5.

Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways.

Romero G, Sánchez E, Pujol M, Pérez P, Codony X, Holenz J, Buschmann H, Pauwels PJ.

Br J Pharmacol. 2006 Aug;148(8):1133-43. Epub 2006 Jul 24.

6.

Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats.

Fisas A, Codony X, Romero G, Dordal A, Giraldo J, Mercé R, Holenz J, Vrang N, Sørensen RV, Heal D, Buschmann H, Pauwels PJ.

Br J Pharmacol. 2006 Aug;148(7):973-83. Epub 2006 Jun 19. Erratum in: Br J Pharmacol. 2007 Jun;151(4):564. Vrang, N [added]; Sørensen, R V [added].

7.

Whole spectrum analysis of ligand efficacy at constitutively active human wild-type and S267K 5-HT6 receptors in HEK-293F cells.

Romero G, Pujol M, Pérez P, Buschmann H, Pauwels PJ.

J Pharmacol Toxicol Methods. 2007 Mar-Apr;55(2):144-50. Epub 2006 May 9.

PMID:
16769227
8.

Medicinal chemistry strategies to 5-HT(6) receptor ligands as potential cognitive enhancers and antiobesity agents.

Holenz J, Pauwels PJ, Díaz JL, Mercè R, Codony X, Buschmann H.

Drug Discov Today. 2006 Apr;11(7-8):283-99. Review.

PMID:
16580970
9.

Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling.

Heusler P, Pauwels PJ, Wurch T, Newman-Tancredi A, Tytgat J, Colpaert FC, Cussac D.

Neuropharmacology. 2005 Dec;49(7):963-76. Epub 2005 Jun 17.

PMID:
15964603
11.

Unravelling multiple ligand-activation binding sites using RASSL receptors.

Pauwels PJ.

Trends Pharmacol Sci. 2003 Oct;24(10):504-7. No abstract available.

PMID:
14559400
12.

Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation.

Pauwels PJ, Colpaert FC.

J Pharmacol Exp Ther. 2003 Nov;307(2):608-14. Epub 2003 Sep 11.

13.

Modulation of 5-HT(1A) receptor-mediated Ca(2+) responses by co-expression with various recombinant G(alpha) proteins in CHO-K1 cells.

Wurch T, Pauwels PJ.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):99-105. Epub 2003 Jul 16.

PMID:
12879209
14.

Pharmacological analysis of a dopamine D(2Short):G(alphao) fusion protein expressed in Sf9 cells.

Gazi L, Wurch T, Lopéz-Giménez JF, Pauwels PJ, Strange PG.

FEBS Lett. 2003 Jun 19;545(2-3):155-60.

17.

Endogenous RGS proteins facilitate dopamine D(2S) receptor coupling to G(alphao) proteins and Ca2+ responses in CHO-K1 cells.

Boutet-Robinet EA, Finana F, Wurch T, Pauwels PJ, De Vries L.

FEBS Lett. 2003 Jan 2;533(1-3):67-71.

18.

Constitutive coupling of a chimeric dopamine D2/alpha 1B receptor to the phospholipase C pathway: inverse agonism to silent antagonism by neuroleptic drugs.

Wurch T, Boutet-Robinet EA, Palmier C, Colpaert FC, Pauwels PJ.

J Pharmacol Exp Ther. 2003 Jan;304(1):380-90.

19.

Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.

Colpaert FC, Tarayre JP, Koek W, Pauwels PJ, Bardin L, Xu XJ, Wiesenfeld-Hallin Z, Cosi C, Carilla-Durand E, Assié MB, Vacher B.

Neuropharmacology. 2002 Nov;43(6):945-58.

PMID:
12423664
20.

Enhanced stability of wild-type and constitutively active alpha(2A)-adrenoceptors by ligands with agonist, silent and inverse agonist properties.

Pauwels PJ, Tardif S.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):134-41. Epub 2002 Jun 6.

PMID:
12122500
21.

Sign-reversal during persistent activation in mu-opioid signal transduction.

Bruins Slot LA, Pauwels PJ, Colpaert FC.

J Theor Biol. 2002 Mar 21;215(2):169-82.

PMID:
12051972
22.

Evidence for protean agonism of RX 831003 at alpha 2A-adrenoceptors by co-expression with different G alpha protein subunits.

Pauwels PJ, Rauly I, Wurch T, Colpaert FC.

Neuropharmacology. 2002 May;42(6):855-63.

PMID:
12015212
23.

Atypical kinetics for a series of putative dopamine antagonists to reverse the low-magnitude Ca2+ phase in the dopamine-bound D2short receptor state.

Pauwels PJ, Koek W.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Jan;365(1):82-5. Epub 2001 Oct 31.

PMID:
11862337
24.

Molecular cloning and expression of the porcine trigeminal ganglion cDNA encoding a 5-ht(1F) receptor.

Bhalla P, Sharma HS, Wurch T, Pauwels PJ, Saxena PR.

Eur J Pharmacol. 2002 Feb 1;436(1-2):23-33.

PMID:
11834243
25.
27.
28.
29.
30.
31.

Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor.

Bhalla P, Sharma HS, Ma X, Wurch T, Pauwels PJ, Saxena PR.

Br J Pharmacol. 2001 Jul;133(6):891-901.

32.

Different regulation of RGS2 mRNA by haloperidol and clozapine.

Robinet EA, Wurch T, Pauwels PJ.

Neuroreport. 2001 Jun 13;12(8):1731-5.

PMID:
11409749
33.

5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.

Koek W, Vacher B, Cosi C, Assié MB, Patoiseau JF, Pauwels PJ, Colpaert FC.

Eur J Pharmacol. 2001 May 25;420(2-3):103-12.

PMID:
11408031
34.

Analysis of ligand activation of alpha 2-adrenoceptor subtypes under conditions of equal G alpha protein stoichiometry.

Pauwels PJ, Wurch T, Tardif S, Finana F, Colpaert FC.

Naunyn Schmiedebergs Arch Pharmacol. 2001 May;363(5):526-36.

PMID:
11383713
35.

Modulation of ligand responses by coupling of alpha(2A)-adrenoceptors to diverse G(alpha)-proteins.

Pauwels PJ, Tardif S, Colpaert FC, Wurch T.

Biochem Pharmacol. 2001 May 1;61(9):1079-92.

PMID:
11301041
36.
37.

Diverse signalling by 5-hydroxytryptamine (5-HT) receptors.

Pauwels PJ.

Biochem Pharmacol. 2000 Dec 15;60(12):1743-50. Review.

PMID:
11108789
39.

Modulation of 5-HT(1A) receptor activation by its interaction with wild-type and mutant g(alphai3) proteins.

Dupuis DS, Wurch T, Tardif S, Colpaert FC, Pauwels PJ.

Neuropharmacology. 2001;40(1):36-47.

PMID:
11077069
40.

Molecular cloning, sequence analysis and pharmacological properties of the porcine 5-HT(1D) receptor.

Bhalla P, Sharma HS, Wurch T, Pauwels PJ, Saxena PR.

Br J Pharmacol. 2000 Nov;131(5):949-57.

41.

New substituted 1-(2,3-dihydrobenzo[1, 4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with alpha(2)-adrenoceptor antagonist activity.

Mayer P, Brunel P, Chaplain C, Piedecoq C, Calmel F, Schambel P, Chopin P, Wurch T, Pauwels PJ, Marien M, Vidaluc JL, Imbert T.

J Med Chem. 2000 Oct 5;43(20):3653-64.

PMID:
11020279
45.

Agonist efficacy at the alpha2A-adrenoceptor:G alpha15 fusion protein: an analysis based on Ca2+ responses.

Pauwels PJ, Finana F, Tardif S, Colpaert FC, Wurch T.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Jun;361(6):672-9.

PMID:
10882043
46.

Zolmitriptan stimulates a Ca(2+)-dependent K(+) current in C6 glioma cells stably expressing recombinant human 5-HT(1B) receptors.

Le Grand B, Panissié A, Perez M, Pauwels PJ, John GW.

Eur J Pharmacol. 2000 Jun 2;397(2-3):297-302.

PMID:
10844127
47.

alpha(2A)-adrenoceptor: G(alphai1) protein-mediated pertussis toxin-resistant attenuation of G(s) coupling to the cyclic AMP pathway.

Rauly I, Ailhaud M, Wurch T, Pauwels PJ.

Biochem Pharmacol. 2000 Jun 15;59(12):1531-8.

PMID:
10799649
48.
50.

Ligand-receptor interactions as controlled by wild-type and mutant Thr(370)Lys alpha2B-adrenoceptor-Galpha15 fusion proteins.

Pauwels PJ, Tardif S, Finana F, Wurch T, Colpaert FC.

J Neurochem. 2000 Jan;74(1):375-84.

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