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A Dual sgRNA Approach for Functional Genomics in Arabidopsis thaliana.

Pauwels L, De Clercq R, Goossens J, Iñigo S, Williams C, Ron M, Britt A, Goossens A.

G3 (Bethesda). 2018 Jun 8. pii: g3.200046.2018. doi: 10.1534/g3.118.200046. [Epub ahead of print]


The hepatic glucocorticoid receptor is crucial for cortisol homeostasis and sepsis survival in humans and male mice.

Jenniskens M, Weckx R, Dufour T, Vander Perre S, Pauwels L, Derde S, Téblick A, Güiza F, Van den Berghe G, Langouche L.

Endocrinology. 2018 May 17. doi: 10.1210/en.2018-00344. [Epub ahead of print]


Age-related differences in GABA levels are driven by bulk tissue changes.

Maes C, Hermans L, Pauwels L, Chalavi S, Leunissen I, Levin O, Cuypers K, Peeters R, Sunaert S, Mantini D, Puts NAJ, Edden RAE, Swinnen SP.

Hum Brain Mapp. 2018 May 2. doi: 10.1002/hbm.24201. [Epub ahead of print]


Author Correction: The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Bossche RV, De Clercq R, Eeckhout D, Ron M, Somers DE, Inzé D, Gevaert K, De Jaeger G, Vandepoele K, Pauwels L, Goossens A.

Nat Commun. 2018 Apr 10;9:16213. doi: 10.1038/ncomms16213.


The neurochemical basis of the contextual interference effect.

Chalavi S, Pauwels L, Heise KF, Zivari Adab H, Maes C, Puts NAJ, Edden RAE, Swinnen SP.

Neurobiol Aging. 2018 Jun;66:85-96. doi: 10.1016/j.neurobiolaging.2018.02.014. Epub 2018 Feb 19.


Challenge to Promote Change: The Neural Basis of the Contextual Interference Effect in Young and Older Adults.

Pauwels L, Chalavi S, Gooijers J, Maes C, Albouy G, Sunaert S, Swinnen SP.

J Neurosci. 2018 Mar 28;38(13):3333-3345. doi: 10.1523/JNEUROSCI.2640-17.2018. Epub 2018 Feb 26.


Age-Dependent Modulations of Resting State Connectivity Following Motor Practice.

Solesio-Jofre E, Beets IAM, Woolley DG, Pauwels L, Chalavi S, Mantini D, Swinnen SP.

Front Aging Neurosci. 2018 Feb 6;10:25. doi: 10.3389/fnagi.2018.00025. eCollection 2018.


STERILE APETALA modulates the stability of a repressor protein complex to control organ size in Arabidopsis thaliana.

Li N, Liu Z, Wang Z, Ru L, Gonzalez N, Baekelandt A, Pauwels L, Goossens A, Xu R, Zhu Z, Inzé D, Li Y.

PLoS Genet. 2018 Feb 5;14(2):e1007218. doi: 10.1371/journal.pgen.1007218. eCollection 2018 Feb.


The choice between deceased- vs living-donor renal transplantation in children: Analysis of data from a Belgian tertiary center.

Van Cauwenberghe K, Raes A, Pauwels L, Dehoorne J, Colenbie L, Dequidt C, Dossche L, Vande Walle J, Prytuła A.

Pediatr Transplant. 2018 Mar;22(2). doi: 10.1111/petr.13140. Epub 2018 Feb 4.


An examination of the interaction between morality and self-control in offending: A study of differences between girls and boys.

Ivert AK, Andersson F, Svensson R, Pauwels LJR, Torstensson Levander M.

Crim Behav Ment Health. 2018 Jun;28(3):282-294. doi: 10.1002/cbm.2065. Epub 2018 Jan 16.


Perceived Group Threat, Perceived Injustice, and Self-Reported Right-Wing Violence: An Integrative Approach to the Explanation Right-Wing Violence.

Pauwels LJR, Heylen B.

J Interpers Violence. 2017 Jun 1:886260517713711. doi: 10.1177/0886260517713711. [Epub ahead of print]


The Role of Autophagy in Critical Illness-induced Liver Damage.

Thiessen SE, Derese I, Derde S, Dufour T, Pauwels L, Bekhuis Y, Pintelon I, Martinet W, Van den Berghe G, Vanhorebeek I.

Sci Rep. 2017 Oct 26;7(1):14150. doi: 10.1038/s41598-017-14405-w.


Relative cortico-subcortical shift in brain activity but preserved training-induced neural modulation in older adults during bimanual motor learning.

Santos Monteiro T, Beets IAM, Boisgontier MP, Gooijers J, Pauwels L, Chalavi S, King B, Albouy G, Swinnen SP.

Neurobiol Aging. 2017 Oct;58:54-67. doi: 10.1016/j.neurobiolaging.2017.06.004. Epub 2017 Jun 19.


Corrigendum: Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.

Sonawane PD, Pollier J, Panda S, Szymanski J, Massalha H, Yona M, Unger T, Malitsky S, Arendt P, Pauwels L, Almekias-Siegl E, Rogachev I, Meir S, Cárdenas PD, Masri A, Petrikov M, Schaller H, Schaffer AA, Kamble A, Giri AP, Goossens A, Aharoni A.

Nat Plants. 2017 Jun 12;3:17101. doi: 10.1038/nplants.2017.101.


The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Vanden Bossche R, De Clercq R, Eeckhout D, Ron M, Somers DE, Inzé D, Gevaert K, De Jaeger G, Vandepoele K, Pauwels L, Goossens A.

Nat Commun. 2017 May 11;8:15235. doi: 10.1038/ncomms15235. Erratum in: Nat Commun. 2018 Apr 10;9:16213.


Economic consequences of legal and illegal drugs: The case of social costs in Belgium.

Lievens D, Vander Laenen F, Verhaeghe N, Putman K, Pauwels L, Hardyns W, Annemans L.

Int J Drug Policy. 2017 Jun;44:50-57. doi: 10.1016/j.drugpo.2017.03.005. Epub 2017 Apr 23.


Postponing a General Practitioner Visit: Describing Social Differences in Thirty-One European Countries.

Detollenaere J, Van Pottelberge A, Hanssens L, Pauwels L, van Loenen T, Willems S.

Health Serv Res. 2017 Dec;52(6):2099-2120. doi: 10.1111/1475-6773.12669. Epub 2017 Feb 19.


The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis.

Miettinen K, Pollier J, Buyst D, Arendt P, Csuk R, Sommerwerk S, Moses T, Mertens J, Sonawane PD, Pauwels L, Aharoni A, Martins J, Nelson DR, Goossens A.

Nat Commun. 2017 Feb 6;8:14153. doi: 10.1038/ncomms14153.


Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.

Sonawane PD, Pollier J, Panda S, Szymanski J, Massalha H, Yona M, Unger T, Malitsky S, Arendt P, Pauwels L, Almekias-Siegl E, Rogachev I, Meir S, Cárdenas PD, Masri A, Petrikov M, Schaller H, Schaffer AA, Kamble A, Giri AP, Goossens A, Aharoni A.

Nat Plants. 2016 Dec 22;3:16205. doi: 10.1038/nplants.2016.205. Erratum in: Nat Plants. 2017 Jun 12;3:17101.


Anatomy of Subcortical Structures Predicts Age-Related Differences in Skill Acquisition.

Chalavi S, Adab HZ, Pauwels L, Beets IAM, van Ruitenbeek P, Boisgontier MP, Monteiro TS, Maes C, Sunaert S, Swinnen SP.

Cereb Cortex. 2018 Feb 1;28(2):459-473. doi: 10.1093/cercor/bhw382.


Alterations in brain white matter contributing to age-related slowing of task switching performance: The role of radial diffusivity and magnetization transfer ratio.

Serbruyns L, Leunissen I, van Ruitenbeek P, Pauwels L, Caeyenberghs K, Solesio-Jofre E, Geurts M, Cuypers K, Meesen RL, Sunaert S, Leemans A, Swinnen SP.

Hum Brain Mapp. 2016 Nov;37(11):4084-4098. doi: 10.1002/hbm.23297.


Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

Iñigo S, Durand AN, Ritter A, Le Gall S, Termathe M, Klassen R, Tohge T, De Coninck B, Van Leene J, De Clercq R, Cammue BP, Fernie AR, Gevaert K, De Jaeger G, Leidel SA, Schaffrath R, Van Lijsebettens M, Pauwels L, Goossens A.

Plant Physiol. 2016 Oct;172(2):858-873. Epub 2016 Aug 8.


The Arabidopsis Iron-Sulfur Protein GRXS17 is a Target of the Ubiquitin E3 Ligases RGLG3 and RGLG4.

Nagels Durand A, Iñigo S, Ritter A, Iniesto E, De Clercq R, Staes A, Van Leene J, Rubio V, Gevaert K, De Jaeger G, Pauwels L, Goossens A.

Plant Cell Physiol. 2016 Sep;57(9):1801-13. doi: 10.1093/pcp/pcw122. Epub 2016 Aug 6.


The Ubiquitin System and Jasmonate Signaling.

Nagels Durand A, Pauwels L, Goossens A.

Plants (Basel). 2016 Jan 9;5(1). pii: E6. doi: 10.3390/plants5010006. Review.


Hypersensitivity of Arabidopsis TAXIMIN1 overexpression lines to light stress is correlated with decreased sinapoyl malate abundance and countered by the antibiotic cefotaxime.

Colling J, Pollier J, Vanden Bossche R, Makunga NP, Pauwels L, Goossens A.

Plant Signal Behav. 2016;11(4):e1143998. doi: 10.1080/15592324.2016.1143998.


Lessons from Domestication: Targeting Cis-Regulatory Elements for Crop Improvement.

Swinnen G, Goossens A, Pauwels L.

Trends Plant Sci. 2016 Jun;21(6):506-515. doi: 10.1016/j.tplants.2016.01.014. Epub 2016 Feb 12. Review.


It's Time for Some "Site"-Seeing: Novel Tools to Monitor the Ubiquitin Landscape in Arabidopsis thaliana.

Walton A, Stes E, Cybulski N, Van Bel M, Iñigo S, Durand AN, Timmerman E, Heyman J, Pauwels L, De Veylder L, Goossens A, De Smet I, Coppens F, Goormachtig S, Gevaert K.

Plant Cell. 2016 Jan;28(1):6-16. doi: 10.1105/tpc.15.00878. Epub 2016 Jan 7. Review.


Challenge to promote change: both young and older adults benefit from contextual interference.

Pauwels L, Vancleef K, Swinnen SP, Beets IA.

Front Aging Neurosci. 2015 Aug 11;7:157. doi: 10.3389/fnagi.2015.00157. eCollection 2015.


The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability.

Pauwels L, Ritter A, Goossens J, Durand AN, Liu H, Gu Y, Geerinck J, Boter M, Vanden Bossche R, De Clercq R, Van Leene J, Gevaert K, De Jaeger G, Solano R, Stone S, Innes RW, Callis J, Goossens A.

Plant Physiol. 2015 Oct;169(2):1405-17. doi: 10.1104/pp.15.00479. Epub 2015 Aug 28.


A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.

Gonzalez N, Pauwels L, Baekelandt A, De Milde L, Van Leene J, Besbrugge N, Heyndrickx KS, Cuéllar Pérez A, Durand AN, De Clercq R, Van De Slijke E, Vanden Bossche R, Eeckhout D, Gevaert K, Vandepoele K, De Jaeger G, Goossens A, Inzé D.

Plant Cell. 2015 Aug;27(8):2273-87. doi: 10.1105/tpc.15.00006. Epub 2015 Jul 31. Erratum in: Plant Cell. 2016 Mar;28(3):824.


Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development.

Colling J, Tohge T, De Clercq R, Brunoud G, Vernoux T, Fernie AR, Makunga NP, Goossens A, Pauwels L.

J Exp Bot. 2015 Aug;66(17):5337-49. doi: 10.1093/jxb/erv291. Epub 2015 Jun 12.


Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth.

Gasperini D, Chételat A, Acosta IF, Goossens J, Pauwels L, Goossens A, Dreos R, Alfonso E, Farmer EE.

PLoS Genet. 2015 Jun 12;11(6):e1005300. doi: 10.1371/journal.pgen.1005300. eCollection 2015 Jun.


Study protocol: SWING--social capital and well-being in neighborhoods in Ghent.

Hardyns W, Vyncke V, Pauwels L, Willems S.

Int J Equity Health. 2015 Apr 9;14:36. doi: 10.1186/s12939-015-0163-1.


Change of a conserved amino acid in the MYC2 and MYC3 transcription factors leads to release of JAZ repression and increased activity.

Goossens J, Swinnen G, Vanden Bossche R, Pauwels L, Goossens A.

New Phytol. 2015 Jun;206(4):1229-37. doi: 10.1111/nph.13398. Epub 2015 Mar 27.


How equal is the relationship between individual social capital and psychological distress? A gendered analysis using cross-sectional data from Ghent (Belgium).

Vyncke V, Hardyns W, Peersman W, Pauwels L, Groenewegen P, Willems S.

BMC Public Health. 2014 Sep 16;14:960. doi: 10.1186/1471-2458-14-960.


Contextual interference in complex bimanual skill learning leads to better skill persistence.

Pauwels L, Swinnen SP, Beets IA.

PLoS One. 2014 Jun 24;9(6):e100906. doi: 10.1371/journal.pone.0100906. eCollection 2014.


Reduced Neural Differentiation Between Feedback Conditions After Bimanual Coordination Training with and without Augmented Visual Feedback.

Beets IA, Gooijers J, Boisgontier MP, Pauwels L, Coxon JP, Wittenberg G, Swinnen SP.

Cereb Cortex. 2015 Jul;25(7):1958-69. doi: 10.1093/cercor/bhu005. Epub 2014 Feb 4.


The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.

Cuéllar Pérez A, Nagels Durand A, Vanden Bossche R, De Clercq R, Persiau G, Van Wees SC, Pieterse CM, Gevaert K, De Jaeger G, Goossens A, Pauwels L.

PLoS One. 2014 Jan 8;9(1):e84891. doi: 10.1371/journal.pone.0084891. eCollection 2014.


Yeast two-hybrid analysis of jasmonate signaling proteins.

Cuéllar AP, Pauwels L, De Clercq R, Goossens A.

Methods Mol Biol. 2013;1011:173-85. doi: 10.1007/978-1-62703-414-2_14.


Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59.

Van der Does D, Leon-Reyes A, Koornneef A, Van Verk MC, Rodenburg N, Pauwels L, Goossens A, Körbes AP, Memelink J, Ritsema T, Van Wees SC, Pieterse CM.

Plant Cell. 2013 Feb;25(2):744-61. doi: 10.1105/tpc.112.108548. Epub 2013 Feb 22.


A MultiSite Gateway™ vector set for the functional analysis of genes in the model Saccharomyces cerevisiae.

Nagels Durand A, Moses T, De Clercq R, Goossens A, Pauwels L.

BMC Mol Biol. 2012 Sep 20;13:30. doi: 10.1186/1471-2199-13-30.


The JAZ proteins: a crucial interface in the jasmonate signaling cascade.

Pauwels L, Goossens A.

Plant Cell. 2011 Sep;23(9):3089-100. doi: 10.1105/tpc.111.089300. Epub 2011 Sep 30. Review.


APETALA2/ETHYLENE RESPONSE FACTOR and basic helix-loop-helix tobacco transcription factors cooperatively mediate jasmonate-elicited nicotine biosynthesis.

De Boer K, Tilleman S, Pauwels L, Vanden Bossche R, De Sutter V, Vanderhaeghen R, Hilson P, Hamill JD, Goossens A.

Plant J. 2011 Jun;66(6):1053-65. doi: 10.1111/j.1365-313X.2011.04566.x. Epub 2011 Apr 5.


The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses.

Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico JM, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla JM, Pauwels L, Witters E, Puga MI, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R.

Plant Cell. 2011 Feb;23(2):701-15. doi: 10.1105/tpc.110.080788. Epub 2011 Feb 18.


Dissection of the one-MegaDalton JAZ1 protein complex.

Geerinck J, Pauwels L, De Jaeger G, Goossens A.

Plant Signal Behav. 2010 Aug;5(8):1039-41. Epub 2010 Aug 1.


NINJA connects the co-repressor TOPLESS to jasmonate signalling.

Pauwels L, Barbero GF, Geerinck J, Tilleman S, Grunewald W, Pérez AC, Chico JM, Bossche RV, Sewell J, Gil E, García-Casado G, Witters E, Inzé D, Long JA, De Jaeger G, Solano R, Goossens A.

Nature. 2010 Apr 1;464(7289):788-91. doi: 10.1038/nature08854.


Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin.

Grunewald W, Vanholme B, Pauwels L, Plovie E, Inzé D, Gheysen G, Goossens A.

EMBO Rep. 2009 Aug;10(8):923-8. doi: 10.1038/embor.2009.103. Epub 2009 Jul 3.


Jasmonate-inducible gene: What does it mean?

Pauwels L, Inzé D, Goossens A.

Trends Plant Sci. 2009 Feb;14(2):87-91. doi: 10.1016/j.tplants.2008.11.005. Epub 2009 Jan 21. Review.


Fine-tuning of early events in the jasmonate response.

Pauwels L, Goossens A.

Plant Signal Behav. 2008 Oct;3(10):846-7.


The auditory-visual integration of anger is impaired in alcoholism: an event-related potentials study.

Maurage P, Philippot P, Joassin F, Pauwels L, Pham T, Prieto EA, Palmero-Soler E, Zanow F, Campanella S.

J Psychiatry Neurosci. 2008 Mar;33(2):111-22.

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