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Items: 10


Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor.

Perera TPS, Jovcheva E, Mevellec L, Vialard J, De Lange D, Verhulst T, Paulussen C, Van De Ven K, King P, Freyne E, Rees DC, Squires M, Saxty G, Page M, Murray CW, Gilissen R, Ward G, Thompson NT, Newell DR, Cheng N, Xie L, Yang J, Platero SJ, Karkera JD, Moy C, Angibaud P, Laquerre S, Lorenzi MV.

Mol Cancer Ther. 2017 Jun;16(6):1010-1020. doi: 10.1158/1535-7163.MCT-16-0589. Epub 2017 Mar 24.


Fermentation assays reveal differences in sugar and (off-) flavor metabolism across different Brettanomyces bruxellensis strains.

Crauwels S, Van Opstaele F, Jaskula-Goiris B, Steensels J, Verreth C, Bosmans L, Paulussen C, Herrera-Malaver B, de Jonge R, De Clippeleer J, Marchal K, De Samblanx G, Willems KA, Verstrepen KJ, Aerts G, Lievens B.

FEMS Yeast Res. 2017 Jan;17(1). pii: fow105. doi: 10.1093/femsyr/fow105. Epub 2016 Dec 11.


Adult Parasitoids of Honeydew-Producing Insects Prefer Honeydew Sugars to Cover their Energetic Needs.

Lenaerts M, Abid L, Paulussen C, Goelen T, Wäckers F, Jacquemyn H, Lievens B.

J Chem Ecol. 2016 Oct;42(10):1028-1036. Epub 2016 Sep 13.


Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species.

Paulussen C, Hallsworth JE, Álvarez-Pérez S, Nierman WC, Hamill PG, Blain D, Rediers H, Lievens B.

Microb Biotechnol. 2017 Mar;10(2):296-322. doi: 10.1111/1751-7915.12367. Epub 2016 Jun 7. Review.


Efficacy of oleylphosphocholine (OlPC) in vitro and in a mouse model of invasive aspergillosis.

Paulussen C, Boulet G, Bosschaerts T, Cos P, Fortin A, Maes L.

Mycoses. 2015 Mar;58(3):127-32. doi: 10.1111/myc.12286. Epub 2015 Jan 15.


Animal models of invasive aspergillosis for drug discovery.

Paulussen C, Boulet GA, Cos P, Delputte P, Maes LJ.

Drug Discov Today. 2014 Sep;19(9):1380-6. doi: 10.1016/j.drudis.2014.06.006. Epub 2014 Jun 13. Review.


Pyrrolo[1,2-α][1,4]benzodiazepines show potent in vitro antifungal activity and significant in vivo efficacy in a Microsporum canis dermatitis model in guinea pigs.

Paulussen C, de Wit K, Boulet G, Cos P, Meerpoel L, Maes L.

J Antimicrob Chemother. 2014 Jun;69(6):1608-10. doi: 10.1093/jac/dku034. Epub 2014 Feb 16.


PLGA nanoparticles and nanosuspensions with amphotericin B: Potent in vitro and in vivo alternatives to Fungizone and AmBisome.

Van de Ven H, Paulussen C, Feijens PB, Matheeussen A, Rombaut P, Kayaert P, Van den Mooter G, Weyenberg W, Cos P, Maes L, Ludwig A.

J Control Release. 2012 Aug 10;161(3):795-803. doi: 10.1016/j.jconrel.2012.05.037. Epub 2012 May 26.


In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models.

de Wit K, Paulussen C, Matheeussen A, van Rossem K, Cos P, Maes L.

Antimicrob Agents Chemother. 2010 Nov;54(11):4927-9. doi: 10.1128/AAC.00730-10. Epub 2010 Aug 30.


Adenoids and tonsils, indications for surgery and immunological consequences of surgery.

Paulussen C, Claes J, Claes G, Jorissen M.

Acta Otorhinolaryngol Belg. 2000;54(3):403-8.


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