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Items: 1 to 50 of 93

1.

Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study.

Pui CH, Rebora P, Schrappe M, Attarbaschi A, Baruchel A, Basso G, Cavé H, Elitzur S, Koh K, Liu HC, Paulsson K, Pieters R, Silverman LB, Stary J, Vora A, Yeoh A, Harrison CJ, Valsecchi MG; Ponte di Legno Childhood ALL Working Group.

J Clin Oncol. 2019 Jan 18:JCO1800822. doi: 10.1200/JCO.18.00822. [Epub ahead of print]

PMID:
30657737
2.

Improved cytogenetic characterization and risk stratification of pediatric acute lymphoblastic leukemia using single nucleotide polymorphism array analysis: A single center experience of 296 cases.

Olsson L, Lundin-Ström KB, Castor A, Behrendtz M, Biloglav A, Norén-Nyström U, Paulsson K, Johansson B.

Genes Chromosomes Cancer. 2018 Nov;57(11):604-607. doi: 10.1002/gcc.22664. Epub 2018 Sep 11.

PMID:
30203896
3.

Genetic predisposition to B-cell acute lymphoblastic leukemia at 14q11.2 is mediated by a CEBPE promoter polymorphism.

Studd JB, Yang M, Li Z, Vijayakrishnan J, Lu Y, Yeoh AE, Paulsson K, Houlston RS.

Leukemia. 2019 Jan;33(1):1-14. doi: 10.1038/s41375-018-0184-z. Epub 2018 Jul 6.

4.

Author Correction: Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2.

Studd JB, Vijayakrishnan J, Yang M, Migliorini G, Paulsson K, Houlston RS.

Nat Commun. 2018 May 25;9:16204. doi: 10.1038/ncomms16204.

5.

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia.

Hyrenius-Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh MP, Song G, Kazi JU, Liu J, Ramakrishan R, Garcia-Ruiz C, Nance S, Gupta P, Zhang J, Rönnstrand L, Hultquist A, Downing JR, Lindkvist-Petersson K, Paulsson K, Järås M, Gruber TA, Ma J, Hagström-Andersson AK.

Nat Commun. 2018 May 2;9(1):1770. doi: 10.1038/s41467-018-04180-1.

6.

Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia.

Gunnarsson R, Dilorenzo S, Lundin-Ström KB, Olsson L, Biloglav A, Lilljebjörn H, Rissler M, Wahlberg P, Lundmark A, Castor A, Behrendtz M, Fioretos T, Paulsson K, Isaksson A, Johansson B.

Leukemia. 2018 Oct;32(10):2117-2125. doi: 10.1038/s41375-018-0092-2. Epub 2018 Mar 12.

7.

Genomic complexity and targeted genes in anaplastic thyroid cancer cell lines.

Woodward EL, Biloglav A, Ravi N, Yang M, Ekblad L, Wennerberg J, Paulsson K.

Endocr Relat Cancer. 2017 Jul;24(7):X2. doi: 10.1530/ERC-16-0522e. No abstract available.

PMID:
28673895
8.

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.

Studd JB, Vijayakrishnan J, Yang M, Migliorini G, Paulsson K, Houlston RS.

Nat Commun. 2017 Mar 3;8:14616. doi: 10.1038/ncomms14616. Erratum in: Nat Commun. 2018 May 25;9:16204.

9.

Genomic complexity and targeted genes in anaplastic thyroid cancer cell lines.

Woodward EL, Biloglav A, Ravi N, Yang M, Ekblad L, Wennerberg J, Paulsson K.

Endocr Relat Cancer. 2017 May;24(5):209-220. doi: 10.1530/ERC-16-0522. Epub 2017 Feb 24. Erratum in: Endocr Relat Cancer. 2017 Jul;24(7):X2.

PMID:
28235956
10.

Near-haploid and low-hypodiploid acute lymphoblastic leukemia: two distinct subtypes with consistently poor prognosis.

Safavi S, Paulsson K.

Blood. 2017 Jan 26;129(4):420-423. doi: 10.1182/blood-2016-10-743765. Epub 2016 Nov 30. Review.

11.

High hyperdiploid childhood acute lymphoblastic leukemia: Chromosomal gains as the main driver event.

Paulsson K.

Mol Cell Oncol. 2015 Jul 6;3(1):e1064555. doi: 10.1080/23723556.2015.1064555. eCollection 2016 Jan-Feb.

12.

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.

Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, Olsson L, Orsmark-Pietras C, von Palffy S, Askmyr M, Rissler M, Schrappe M, Cario G, Castor A, Pronk CJ, Behrendtz M, Mitelman F, Johansson B, Paulsson K, Andersson AK, Fontes M, Fioretos T.

Nat Commun. 2016 Jun 6;7:11790. doi: 10.1038/ncomms11790.

13.

The genetic landscape of paediatric de novo acute myeloid leukaemia as defined by single nucleotide polymorphism array and exon sequencing of 100 candidate genes.

Olsson L, Zettermark S, Biloglav A, Castor A, Behrendtz M, Forestier E, Paulsson K, Johansson B.

Br J Haematol. 2016 Jul;174(2):292-301. doi: 10.1111/bjh.14056. Epub 2016 Mar 28.

PMID:
27022003
14.

Single nucleotide polymorphism array analysis of clonal evolution in younger adult acute lymphoblastic leukemia.

Dirse V, Gineikiene E, Zvirblis T, Bertasiute R, Paulsson K, Griskevicius L.

Leuk Lymphoma. 2016 Nov;57(11):2716-9. doi: 10.3109/10428194.2016.1160081. Epub 2016 Mar 21. No abstract available.

PMID:
26999635
15.

Patterns and frequencies of acquired and constitutional uniparental isodisomies in pediatric and adult B-cell precursor acute lymphoblastic leukemia.

Lundin KB, Olsson L, Safavi S, Biloglav A, Paulsson K, Johansson B.

Genes Chromosomes Cancer. 2016 May;55(5):472-9. doi: 10.1002/gcc.22349. Epub 2016 Feb 4.

PMID:
26773847
16.

HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma.

Thuring C, Follin E, Geironson L, Freyhult E, Junghans V, Harndahl M, Buus S, Paulsson KM.

Br J Cancer. 2015 Dec 1;113(11):1640. doi: 10.1038/bjc.2015.387. No abstract available.

17.

Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.

Safavi S, Olsson L, Biloglav A, Veerla S, Blendberg M, Tayebwa J, Behrendtz M, Castor A, Hansson M, Johansson B, Paulsson K.

Oncotarget. 2015 Dec 15;6(40):42793-802. doi: 10.18632/oncotarget.6000.

18.

HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma.

Thuring C, Follin E, Geironson L, Freyhult E, Junghans V, Harndahl M, Buus S, Paulsson KM.

Br J Cancer. 2015 Sep 15;113(6):952-62. doi: 10.1038/bjc.2015.297. Epub 2015 Aug 27. Erratum in: Br J Cancer. 2015 Dec 1;113(11):1640.

19.

Chromosome gains drive childhood ALL.

Paulsson K.

Oncotarget. 2015 Aug 14;6(23):19360-1. No abstract available.

20.

The clinical impact of IKZF1 deletions in paediatric B-cell precursor acute lymphoblastic leukaemia is independent of minimal residual disease stratification in Nordic Society for Paediatric Haematology and Oncology treatment protocols used between 1992 and 2013.

Olsson L, Ivanov Öfverholm I, Norén-Nyström U, Zachariadis V, Nordlund J, Sjögren H, Golovleva I, Nordgren A, Paulsson K, Heyman M, Barbany G, Johansson B.

Br J Haematol. 2015 Sep;170(6):847-58. doi: 10.1111/bjh.13514. Epub 2015 May 27.

PMID:
26018335
21.

The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

Paulsson K, Lilljebjörn H, Biloglav A, Olsson L, Rissler M, Castor A, Barbany G, Fogelstrand L, Nordgren A, Sjögren H, Fioretos T, Johansson B.

Nat Genet. 2015 Jun;47(6):672-6. doi: 10.1038/ng.3301. Epub 2015 May 11.

PMID:
25961940
22.

Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A.

Karrman K, Castor A, Behrendtz M, Forestier E, Olsson L, Ehinger M, Biloglav A, Fioretos T, Paulsson K, Johansson B.

J Hematol Oncol. 2015 Apr 24;8:42. doi: 10.1186/s13045-015-0138-0.

23.

Cooperative genetic changes in pediatric B-cell precursor acute lymphoblastic leukemia with deletions or mutations of IKZF1.

Olsson L, Albitar F, Castor A, Behrendtz M, Biloglav A, Paulsson K, Johansson B.

Genes Chromosomes Cancer. 2015 May;54(5):315-25. doi: 10.1002/gcc.22245. Epub 2015 Feb 26.

PMID:
25727050
24.

A population-based single nucleotide polymorphism array analysis of genomic aberrations in younger adult acute lymphoblastic leukemia patients.

Dirse V, Bertasiute A, Gineikiene E, Zvirblis T, Dambrauskiene R, Gerbutavicius R, Juozaityte E, Malciute L, Paulsson K, Griskevicius L.

Genes Chromosomes Cancer. 2015 May;54(5):326-33. doi: 10.1002/gcc.22246. Epub 2015 Feb 23.

PMID:
25706938
25.

Risk of RAS in relapsed childhood ALL.

Paulsson K.

Blood. 2014 Nov 27;124(23):3338-9. doi: 10.1182/blood-2014-10-605030. No abstract available.

26.

Novel gene targets detected by genomic profiling in a consecutive series of 126 adults with acute lymphoblastic leukemia.

Safavi S, Hansson M, Karlsson K, Biloglav A, Johansson B, Paulsson K.

Haematologica. 2015 Jan;100(1):55-61. doi: 10.3324/haematol.2014.112912. Epub 2014 Sep 26.

27.
28.

Tapasin and human leukocyte antigen class I dysregulation correlates with survival in glioblastoma multiforme.

Thuring C, Geironson L, Paulsson K.

Anticancer Agents Med Chem. 2014;14(8):1101-9.

PMID:
25175688
29.

Allelic variants of PRDM9 associated with high hyperdiploid childhood acute lymphoblastic leukaemia.

Woodward EL, Olsson ML, Johansson B, Paulsson K.

Br J Haematol. 2014 Sep;166(6):947-9. doi: 10.1111/bjh.12914. Epub 2014 Apr 23. No abstract available.

PMID:
24754746
30.

Tapasin facilitation of natural HLA-A and -B allomorphs is strongly influenced by peptide length, depends on stability, and separates closely related allomorphs.

Geironson L, Thuring C, Harndahl M, Rasmussen M, Buus S, Røder G, Paulsson KM.

J Immunol. 2013 Oct 1;191(7):3939-47. doi: 10.4049/jimmunol.1201741. Epub 2013 Aug 26.

31.

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

Olsson L, Castor A, Behrendtz M, Biloglav A, Forestier E, Paulsson K, Johansson B.

Leukemia. 2014 Feb;28(2):302-10. doi: 10.1038/leu.2013.206. Epub 2013 Jul 4.

PMID:
23823658
32.

High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols.

Paulsson K, Forestier E, Andersen MK, Autio K, Barbany G, Borgström G, Cavelier L, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kjeldsen E, Nordgren A, Palmqvist L, Johansson B; Nordic Society of Pediatric Hematology and Oncology (NOPHO); Swedish Cytogenetic Leukemia Study Group (SCLSG); NOPHO Leukemia Cytogenetic Study Group (NLCSG).

Haematologica. 2013 Sep;98(9):1424-32. doi: 10.3324/haematol.2013.085852. Epub 2013 May 3.

33.

Genomic heterogeneity in acute leukemia.

Paulsson K.

Cytogenet Genome Res. 2013;139(3):174-80. doi: 10.1159/000346797. Epub 2013 Jan 26. Review.

PMID:
23363651
34.

In silico peptide-binding predictions of passerine MHC class I reveal similarities across distantly related species, suggesting convergence on the level of protein function.

Follin E, Karlsson M, Lundegaard C, Nielsen M, Wallin S, Paulsson K, Westerdahl H.

Immunogenetics. 2013 Apr;65(4):299-311. doi: 10.1007/s00251-012-0676-3. Epub 2013 Jan 29.

PMID:
23358931
35.

Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements.

Paulsson K, Harrison CJ, Andersen MK, Chilton L, Nordgren A, Moorman AV, Johansson B.

Leukemia. 2013 Apr;27(4):974-7. doi: 10.1038/leu.2012.263. Epub 2012 Sep 11. No abstract available.

PMID:
23032693
36.

Retained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma.

Nord KH, Paulsson K, Veerla S, Wejde J, Brosjö O, Mandahl N, Mertens F.

Neoplasia. 2012 Sep;14(9):807-12.

37.

Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia.

Safavi S, Forestier E, Golovleva I, Barbany G, Nord KH, Moorman AV, Harrison CJ, Johansson B, Paulsson K.

Leukemia. 2013 Jan;27(1):248-50. doi: 10.1038/leu.2012.227. Epub 2012 Aug 14. No abstract available.

PMID:
22889820
38.
39.

Stability of peptide-HLA-I complexes and tapasin folding facilitation--tools to define immunogenic peptides.

Geironson L, Røder G, Paulsson K.

FEBS Lett. 2012 May 7;586(9):1336-43. doi: 10.1016/j.febslet.2012.03.045. Epub 2012 Mar 28.

40.

High frequency of BTG1 deletions in acute lymphoblastic leukemia in children with down syndrome.

Lundin C, Hjorth L, Behrendtz M, Nordgren A, Palmqvist L, Andersen MK, Biloglav A, Forestier E, Paulsson K, Johansson B.

Genes Chromosomes Cancer. 2012 Feb;51(2):196-206. doi: 10.1002/gcc.20944. Epub 2011 Nov 10.

PMID:
22072402
41.

Clonal evolution through loss of chromosomes and subsequent polyploidization in chondrosarcoma.

Olsson L, Paulsson K, Bovée JV, Nord KH.

PLoS One. 2011;6(9):e24977. doi: 10.1371/journal.pone.0024977. Epub 2011 Sep 20. Erratum in: PLoS One. 2011;6(10). doi:10.1371/annotation/8f845569-8244-416b-b15e-89562177ce32.

42.

Cytotoxic effect of menadione and sodium orthovanadate in combination on human glioma cells.

Delwar ZM, Avramidis D, Follin E, Hua Y, Siden Å, Cruz M, Paulsson KM, Yakisich JS.

Invest New Drugs. 2012 Aug;30(4):1302-10. doi: 10.1007/s10637-011-9680-y. Epub 2011 May 10.

PMID:
21553345
43.

Tapasin discriminates peptide-human leukocyte antigen-A*02:01 complexes formed with natural ligands.

Roder G, Geironson L, Rasmussen M, Harndahl M, Buus S, Paulsson K.

J Biol Chem. 2011 Jun 10;286(23):20547-57. doi: 10.1074/jbc.M111.230151. Epub 2011 Apr 25.

44.

Cytogenetic and molecular genetic characterization of the 'high hyperdiploid' B-cell precursor acute lymphoblastic leukaemia cell line MHH-CALL-2 reveals a near-haploid origin.

Aburawi HE, Biloglav A, Johansson B, Paulsson K.

Br J Haematol. 2011 Jul;154(2):275-7. doi: 10.1111/j.1365-2141.2011.08601.x. Epub 2011 Apr 26. No abstract available.

PMID:
21518330
45.

The insulin receptor substrate 4 gene (IRS4) is mutated in paediatric T-cell acute lymphoblastic leukaemia.

Karrman K, Isaksson M, Paulsson K, Johansson B.

Br J Haematol. 2011 Nov;155(4):516-9. doi: 10.1111/j.1365-2141.2011.08709.x. Epub 2011 Apr 25. No abstract available.

PMID:
21517825
47.

t(9;11)(p22;p15) [NUP98/PSIP1] is a poor prognostic marker associated with de novo acute myeloid leukaemia expressing both mature and immature surface antigens.

Lundin C, Horvat A, Karlsson K, Olofsson T, Paulsson K, Johansson B.

Leuk Res. 2011 Jun;35(6):e75-6. doi: 10.1016/j.leukres.2010.11.022. Epub 2010 Dec 17. No abstract available.

PMID:
21168209
48.

Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

Paulsson K, Forestier E, Lilljebjörn H, Heldrup J, Behrendtz M, Young BD, Johansson B.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21719-24. doi: 10.1073/pnas.1006981107. Epub 2010 Nov 22.

49.

Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C.

Vita MF, Nagachar N, Avramidis D, Delwar ZM, Cruz MH, Siden Å, Paulsson KM, Yakisich JS.

Invest New Drugs. 2011 Dec;29(6):1314-20. doi: 10.1007/s10637-010-9489-0. Epub 2010 Jul 13.

50.

Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations.

Davidsson J, Paulsson K, Lindgren D, Lilljebjörn H, Chaplin T, Forestier E, Andersen MK, Nordgren A, Rosenquist R, Fioretos T, Young BD, Johansson B.

Leukemia. 2010 May;24(5):924-31. doi: 10.1038/leu.2010.39. Epub 2010 Mar 18.

PMID:
20237506

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