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Items: 1 to 50 of 128

1.

Whole-genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation.

Paulsson JO, Backman S, Wang N, Stenman A, Crona J, Thutkawkorapin J, Ghaderi M, Tham E, Stålberg P, Zedenius J, Juhlin CC.

J Pathol. 2019 Oct 17. doi: 10.1002/path.5359. [Epub ahead of print]

PMID:
31621921
2.

Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator.

Riglar DT, Richmond DL, Potvin-Trottier L, Verdegaal AA, Naydich AD, Bakshi S, Leoncini E, Lyon LG, Paulsson J, Silver PA.

Nat Commun. 2019 Oct 11;10(1):4665. doi: 10.1038/s41467-019-12638-z.

3.

Stochastic antagonism between two proteins governs a bacterial cell fate switch.

Lord ND, Norman TM, Yuan R, Bakshi S, Losick R, Paulsson J.

Science. 2019 Oct 4;366(6461):116-120. doi: 10.1126/science.aaw4506.

PMID:
31604312
4.

Kinetic Uncertainty Relations for the Control of Stochastic Reaction Networks.

Yan J, Hilfinger A, Vinnicombe G, Paulsson J.

Phys Rev Lett. 2019 Sep 6;123(10):108101. doi: 10.1103/PhysRevLett.123.108101.

PMID:
31573304
5.

Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease.

Hysek M, Paulsson JO, Jatta K, Shabo I, Stenman A, Höög A, Larsson C, Zedenius J, Juhlin CC.

Cancers (Basel). 2019 Sep 26;11(10). pii: E1443. doi: 10.3390/cancers11101443.

6.

A universal control system for synthetic gene networks.

Olsman N, Paulsson J.

Nature. 2019 Jun;570(7762):452-453. doi: 10.1038/d41586-019-01772-9. No abstract available.

PMID:
31235938
7.

TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up.

Stenman A, Hysek M, Jatta K, Bränström R, Darai-Ramqvist E, Paulsson JO, Wang N, Larsson C, Zedenius J, Juhlin CC.

Endocr Pathol. 2019 Sep;30(3):246-248. doi: 10.1007/s12022-019-09580-7.

PMID:
31154561
8.

Quantification of very low-abundant proteins in bacteria using the HaloTag and epi-fluorescence microscopy.

Lepore A, Taylor H, Landgraf D, Okumus B, Jaramillo-Riveri S, McLaren L, Bakshi S, Paulsson J, Karoui ME.

Sci Rep. 2019 May 27;9(1):7902. doi: 10.1038/s41598-019-44278-0.

9.

Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.

Strell C, Paulsson J, Jin SB, Tobin NP, Mezheyeuski A, Roswall P, Mutgan C, Mitsios N, Johansson H, Wickberg SM, Svedlund J, Nilsson M, Hall P, Mulder J, Radisky DC, Pietras K, Bergh J, Lendahl U, Wärnberg F, Östman A.

J Natl Cancer Inst. 2019 Sep 1;111(9):983-995. doi: 10.1093/jnci/djy234.

PMID:
30816935
10.

Design of Y2 Receptor Selective and Proteolytically Stable PYY3-36 Analogues.

Østergaard S, Kofoed J, Paulsson JF, Madsen KG, Jorgensen R, Wulff BS.

J Med Chem. 2018 Dec 13;61(23):10519-10530. doi: 10.1021/acs.jmedchem.8b01046. Epub 2018 Nov 20.

PMID:
30399314
11.

TERT Immunohistochemistry Is a Poor Predictor of TERT Promoter Mutations and Gene Expression in Follicular Thyroid Carcinoma.

Paulsson JO, Olander A, Haglund F, Zedenius J, Juhlin CC.

Endocr Pathol. 2018 Dec;29(4):380-383. doi: 10.1007/s12022-018-9551-6. No abstract available.

12.

Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3338.

13.

Papillary thyroid carcinoma with pleomorphic tumor giant cells in a pregnant woman - a case report.

Paulsson JO, Zedenius J, Juhlin CC.

BMC Endocr Disord. 2018 Jul 5;18(1):46. doi: 10.1186/s12902-018-0275-x.

14.

TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma.

Svahn F, Paulsson JO, Stenman A, Fotouhi O, Mu N, Murtha TD, Korah R, Carling T, Bäckdahl M, Wang N, Juhlin CC, Larsson C.

Int J Mol Med. 2018 Sep;42(3):1675-1683. doi: 10.3892/ijmm.2018.3735. Epub 2018 Jun 20.

PMID:
29956721
15.

Monolith affinity chromatography for the rapid quantification of a single-chain variable fragment immunotoxin.

Satzer P, Sommer R, Paulsson J, Rodler A, Zehetner R, Hofstädter K, Klade C, Jungbauer A.

J Sep Sci. 2018 Aug;41(15):3051-3059. doi: 10.1002/jssc.201800257. Epub 2018 Jul 1.

16.

TERT promoter mutational screening as a tool to predict malignant behaviour in follicular thyroid tumours-three examples from the clinical routine.

Hysek M, Paulsson JO, Wang N, Jatta K, Lindh C, Fuentes-Martinez N, Shabo I, Zedenius J, Juhlin CC.

Virchows Arch. 2018 Nov;473(5):639-643. doi: 10.1007/s00428-018-2386-1. Epub 2018 Jun 2.

PMID:
29860621
17.

Comprehensive Genetic Analysis of Follicular Thyroid Carcinoma Predicts Prognosis Independent of Histology.

Nicolson NG, Murtha TD, Dong W, Paulsson JO, Choi J, Barbieri AL, Brown TC, Kunstman JW, Larsson C, Prasad ML, Korah R, Lifton RP, Juhlin CC, Carling T.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2640-2650. doi: 10.1210/jc.2018-00277.

PMID:
29726952
18.

TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours.

Paulsson JO, Mu N, Shabo I, Wang N, Zedenius J, Larsson C, Juhlin CC.

Endocr Relat Cancer. 2018 Jul;25(7):723-733. doi: 10.1530/ERC-18-0050. Epub 2018 Apr 24.

PMID:
29692346
19.

Microfluidics and single-cell microscopy to study stochastic processes in bacteria.

Potvin-Trottier L, Luro S, Paulsson J.

Curr Opin Microbiol. 2018 Jun;43:186-192. doi: 10.1016/j.mib.2017.12.004. Epub 2018 Feb 27. Review.

20.

Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor.

Xu B, Vasile S, Østergaard S, Paulsson JF, Pruner J, Åqvist J, Wulff BS, Gutiérrez-de-Terán H, Larhammar D.

Mol Pharmacol. 2018 Apr;93(4):323-334. doi: 10.1124/mol.117.110627. Epub 2018 Jan 24.

PMID:
29367257
21.

Single-cell microscopy of suspension cultures using a microfluidics-assisted cell screening platform.

Okumus B, Baker CJ, Arias-Castro JC, Lai GC, Leoncini E, Bakshi S, Luro S, Landgraf D, Paulsson J.

Nat Protoc. 2018 Jan;13(1):170-194. doi: 10.1038/nprot.2017.127. Epub 2017 Dec 21.

22.

Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma.

Svahn F, Juhlin CC, Paulsson JO, Fotouhi O, Zedenius J, Larsson C, Stenman A.

Clin Endocrinol (Oxf). 2018 Feb;88(2):343-345. doi: 10.1111/cen.13513. Epub 2017 Nov 27. No abstract available.

PMID:
29130501
23.

Noise in a phosphorelay drives stochastic entry into sporulation in Bacillus subtilis.

Russell JR, Cabeen MT, Wiggins PA, Paulsson J, Losick R.

EMBO J. 2017 Oct 2;36(19):2856-2869. doi: 10.15252/embj.201796988. Epub 2017 Aug 24.

25.

Use of a microfluidic platform to uncover basic features of energy and environmental stress responses in individual cells of Bacillus subtilis.

Cabeen MT, Russell JR, Paulsson J, Losick R.

PLoS Genet. 2017 Jul 20;13(7):e1006901. doi: 10.1371/journal.pgen.1006901. eCollection 2017 Jul.

26.

Ribosomes are optimized for autocatalytic production.

Reuveni S, Ehrenberg M, Paulsson J.

Nature. 2017 Jul 19;547(7663):293-297. doi: 10.1038/nature22998.

PMID:
28726822
27.

Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.

Strell C, Norberg KJ, Mezheyeuski A, Schnittert J, Kuninty PR, Moro CF, Paulsson J, Schultz NA, Calatayud D, Löhr JM, Frings O, Verbeke CS, Heuchel RL, Prakash J, Johansen JS, Östman A.

Br J Cancer. 2017 Jun 27;117(1):65-77. doi: 10.1038/bjc.2017.140. Epub 2017 May 18.

28.

Cell-Size Control and Homeostasis in Bacteria.

Taheri-Araghi S, Bradde S, Sauls JT, Hill NS, Levin PA, Paulsson J, Vergassola M, Jun S.

Curr Biol. 2017 May 8;27(9):1392. doi: 10.1016/j.cub.2017.04.028. No abstract available.

29.

The processive kinetics of gene conversion in bacteria.

Paulsson J, El Karoui M, Lindell M, Hughes D.

Mol Microbiol. 2017 Jun;104(5):752-760. doi: 10.1111/mmi.13661. Epub 2017 Mar 13.

30.

High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancer.

Paulsson J, Rydén L, Strell C, Frings O, Tobin NP, Fornander T, Bergh J, Landberg G, Stål O, Östman A.

J Pathol Clin Res. 2016 Sep 14;3(1):38-43. doi: 10.1002/cjp2.56. eCollection 2017 Jan.

31.

Random versus Cell Cycle-Regulated Replication Initiation in Bacteria: Insights from Studying Vibrio cholerae Chromosome 2.

Ramachandran R, Jha J, Paulsson J, Chattoraj D.

Microbiol Mol Biol Rev. 2016 Nov 30;81(1). pii: e00033-16. Print 2017 Mar. Review.

32.

Synchronous long-term oscillations in a synthetic gene circuit.

Potvin-Trottier L, Lord ND, Vinnicombe G, Paulsson J.

Nature. 2016 Oct 27;538(7626):514-517. doi: 10.1038/nature19841. Epub 2016 Oct 12.

33.

Amount of stroma is associated with mammographic density and stromal expression of oestrogen receptor in normal breast tissues.

Gabrielson M, Chiesa F, Paulsson J, Strell C, Behmer C, Rönnow K, Czene K, Östman A, Hall P.

Breast Cancer Res Treat. 2016 Jul;158(2):253-61. doi: 10.1007/s10549-016-3877-x. Epub 2016 Jun 27.

PMID:
27349429
34.

Corrigendum: Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.

Okumus B, Landgraf D, Lai GC, Bakshi S, Arias-Castro JC, Yildiz S, Huh D, Fernandez-Lopez R, Peterson CN, Toprak E, El Karoui M, Paulsson J.

Nat Commun. 2016 Jun 24;7:12130. doi: 10.1038/ncomms12130. No abstract available.

35.

Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.

Okumus B, Landgraf D, Lai GC, Bakshi S, Arias-Castro JC, Yildiz S, Huh D, Fernandez-Lopez R, Peterson CN, Toprak E, El Karoui M, Paulsson J.

Nat Commun. 2016 May 18;7:11641. doi: 10.1038/ncomms11641. Erratum in: Nat Commun. 2016 Jun 24;7:12130. Bakhsi, Somenath [corrected to Bakshi, Somenath].

36.

Exploiting Natural Fluctuations to Identify Kinetic Mechanisms in Sparsely Characterized Systems.

Hilfinger A, Norman TM, Paulsson J.

Cell Syst. 2016 Apr 27;2(4):251-9. doi: 10.1016/j.cels.2016.04.002. Epub 2016 Apr 27.

37.

Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.

Uphoff S, Lord ND, Okumus B, Potvin-Trottier L, Sherratt DJ, Paulsson J.

Science. 2016 Mar 4;351(6277):1094-7. doi: 10.1126/science.aac9786.

38.

Constraints on Fluctuations in Sparsely Characterized Biological Systems.

Hilfinger A, Norman TM, Vinnicombe G, Paulsson J.

Phys Rev Lett. 2016 Feb 5;116(5):058101. doi: 10.1103/PhysRevLett.116.058101. Epub 2016 Feb 1.

39.

Visualization of Periplasmic and Cytoplasmic Proteins with a Self-Labeling Protein Tag.

Ke N, Landgraf D, Paulsson J, Berkmen M.

J Bacteriol. 2016 Jan 19;198(7):1035-43. doi: 10.1128/JB.00864-15.

40.

Accurate concentration control of mitochondria and nucleoids.

Jajoo R, Jung Y, Huh D, Viana MP, Rafelski SM, Springer M, Paulsson J.

Science. 2016 Jan 8;351(6269):169-72. doi: 10.1126/science.aaa8714.

41.

Absence of the BRAF V600E mutation in pheochromocytoma.

Paulsson JO, Svahn F, Welander J, Brunaud L, Söderkvist P, Gimm O, Stenman A, Juhlin CC.

J Endocrinol Invest. 2016 Jun;39(6):715-6. doi: 10.1007/s40618-015-0420-6. Epub 2015 Dec 28.

PMID:
26710756
42.

Stochastic Switching of Cell Fate in Microbes.

Norman TM, Lord ND, Paulsson J, Losick R.

Annu Rev Microbiol. 2015;69:381-403. doi: 10.1146/annurev-micro-091213-112852. Epub 2015 Aug 21. Review.

PMID:
26332088
43.

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells.

Hong J, Tobin NP, Rundqvist H, Li T, Lavergne M, García-Ibáñez Y, Qin H, Paulsson J, Zeitelhofer M, Adzemovic MZ, Nilsson I, Roswall P, Hartman J, Johnson RS, Östman A, Bergh J, Poljakovic M, Genové G.

J Natl Cancer Inst. 2015 Aug 21;107(10). pii: djv209. doi: 10.1093/jnci/djv209. Print 2015 Oct. Erratum in: J Natl Cancer Inst. 2016 Mar;108(3). pii: djv434. doi: 10.1093/jnci/djv434.

44.

The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling.

Williams MJ, Eriksson A, Shaik M, Voisin S, Yamskova O, Paulsson J, Thombare K, Fredriksson R, Schiöth HB.

Mol Endocrinol. 2015 Sep;29(9):1303-19. doi: 10.1210/ME.2015-1077. Epub 2015 Jul 13.

45.

Systems biology: Defiant daughters and coordinated cousins.

Hilfinger A, Paulsson J.

Nature. 2015 Mar 26;519(7544):422-3. doi: 10.1038/nature14210. Epub 2015 Mar 11. No abstract available.

PMID:
25762142
46.

In vivo seeding and cross-seeding of localized amyloidosis: a molecular link between type 2 diabetes and Alzheimer disease.

Oskarsson ME, Paulsson JF, Schultz SW, Ingelsson M, Westermark P, Westermark GT.

Am J Pathol. 2015 Mar;185(3):834-46. doi: 10.1016/j.ajpath.2014.11.016. Epub 2015 Feb 17.

PMID:
25700985
47.

Cell-size control and homeostasis in bacteria.

Taheri-Araghi S, Bradde S, Sauls JT, Hill NS, Levin PA, Paulsson J, Vergassola M, Jun S.

Curr Biol. 2015 Feb 2;25(3):385-391. doi: 10.1016/j.cub.2014.12.009. Epub 2014 Dec 24. Erratum in: Curr Biol. 2017 May 8;27(9):1392.

48.

Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.

Truffaux N, Philippe C, Paulsson J, Andreiuolo F, Guerrini-Rousseau L, Cornilleau G, Le Dret L, Richon C, Lacroix L, Puget S, Geoerger B, Vassal G, Östman A, Grill J.

Neuro Oncol. 2015 Jul;17(7):953-64. doi: 10.1093/neuonc/nou330. Epub 2014 Dec 21.

49.

PDGF receptors in tumor biology: prognostic and predictive potential.

Paulsson J, Ehnman M, Östman A.

Future Oncol. 2014;10(9):1695-708. doi: 10.2217/fon.14.83. Review.

PMID:
25145436
50.

Design and Synthesis of Peptide YY Analogues with C-terminal Backbone Amide-to-Ester Modifications.

Albertsen L, Andersen JJ, Paulsson JF, Thomsen JK, Norrild JC, Strømgaard K.

ACS Med Chem Lett. 2013 Oct 21;4(12):1228-32. doi: 10.1021/ml400335g. eCollection 2013 Dec 12.

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