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Items: 1 to 50 of 185

1.

Evidence for Chemopreventive and resilience activity of licorice: Glycyrrhiza glabra and G. inflata extracts modulate estrogen metabolism in ACI rats.

Wang S, Dunlap TL, Huang L, Liu Y, Simmler C, Lantvit DD, Crosby J, Howell CE, Dong H, Chen SN, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Cancer Prev Res (Phila). 2018 Oct 4. pii: canprevres.0178.2018. doi: 10.1158/1940-6207.CAPR-18-0178. [Epub ahead of print]

PMID:
30287522
2.

India-United States Dialogue on Traditional Medicine: Toward Collaborative Research and Generation of an Evidence Base.

White JD, O'Keefe BR, Sharma J, Javed G, Nukala V, Ganguly A, Khan IA, Kumar NB, Mukhtar H, Pauli GF, Walker L, Sivaram S, Rajaraman P, Trimble EL.

J Glob Oncol. 2018 Sep;(4):1-10. doi: 10.1200/JGO.17.00099. Epub 2017 Nov 16.

PMID:
30241135
3.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2018 Jul 13. doi: 10.1039/c7np00064b. [Epub ahead of print] Review.

PMID:
30003207
4.

Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin.

Choules MP, Klein LL, Lankin DC, McAlpine JB, Cho SH, Cheng J, Lee H, Suh JW, Jaki BU, Franzblau SG, Pauli GF.

J Org Chem. 2018 Jun 15;83(12):6664-6672. doi: 10.1021/acs.joc.8b00988. Epub 2018 May 24.

5.

Countercurrent separation assisted identification of two mammalian steroid hormones in Vitex negundo.

Fan Q, Liu Y, Kulakowski D, Chen S, Friesen JB, Pauli GF, Song Q.

J Chromatogr A. 2018 Jun 8;1553:108-115. doi: 10.1016/j.chroma.2018.04.033. Epub 2018 Apr 21.

PMID:
29699871
6.

Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.

Hajirahimkhan A, Mbachu O, Simmler C, Ellis SG, Dong H, Nikolic D, Lankin DC, van Breemen RB, Chen SN, Pauli GF, Dietz BM, Bolton JL.

J Nat Prod. 2018 Apr 27;81(4):966-975. doi: 10.1021/acs.jnatprod.7b01070. Epub 2018 Apr 11.

7.

Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives.

Liu Y, Friesen JB, McAlpine JB, Lankin DC, Chen SN, Pauli GF.

J Nat Prod. 2018 Mar 23;81(3):679-690. doi: 10.1021/acs.jnatprod.7b00945. Epub 2018 Mar 7.

PMID:
29513526
8.

Pharmacognosy in the digital era: shifting to contextualized metabolomics.

Allard PM, Bisson J, Azzollini A, Pauli GF, Cordell GA, Wolfender JL.

Curr Opin Biotechnol. 2018 Feb 27;54:57-64. doi: 10.1016/j.copbio.2018.02.010. [Epub ahead of print] Review.

PMID:
29499476
9.

The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites.

Liu Y, Zhang Y, Chen SN, Friesen JB, Nikolić D, Choules MP, McAlpine JB, Lankin DC, Gemeinhart RA, Pauli GF.

Fitoterapia. 2018 Jun;127:212-219. doi: 10.1016/j.fitote.2018.02.024. Epub 2018 Feb 21.

PMID:
29474979
10.

Centrifugal partition chromatography enables selective enrichment of trimeric and tetrameric proanthocyanidins for biomaterial development.

Phansalkar RS, Nam JW, Chen SN, McAlpine JB, Leme AA, Aydin B, Bedran-Russo AK, Pauli GF.

J Chromatogr A. 2018 Feb 2;1535:55-62. doi: 10.1016/j.chroma.2017.12.050. Epub 2017 Dec 21.

PMID:
29331224
11.

Integrated analytical assets aid botanical authenticity and adulteration management.

Simmler C, Graham JG, Chen SN, Pauli GF.

Fitoterapia. 2018 Sep;129:401-414. doi: 10.1016/j.fitote.2017.11.017. Epub 2017 Nov 22. Review.

PMID:
29175549
12.

Structural Sequencing of Oligopeptides Aided by 1H Iterative Full-Spin Analysis.

Gao W, McAlpine JB, Choules MP, Napolitano JG, Lankin DC, Simmler C, Ho NA, Lee H, Suh JW, Burton IW, Cho S, Franzblau SG, Chen SN, Pauli GF.

J Nat Prod. 2017 Oct 27;80(10):2630-2643. doi: 10.1021/acs.jnatprod.7b00207. Epub 2017 Oct 16.

PMID:
29035048
13.

Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism.

Dunlap TL, Howell CE, Mukand N, Chen SN, Pauli GF, Dietz BM, Bolton JL.

Chem Res Toxicol. 2017 Nov 20;30(11):2084-2092. doi: 10.1021/acs.chemrestox.7b00237. Epub 2017 Oct 19.

14.

Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats.

Keiler AM, Macejova D, Dietz BM, Bolton JL, Pauli GF, Chen SN, van Breemen RB, Nikolic D, Goerl F, Muders MH, Zierau O, Vollmer G.

J Steroid Biochem Mol Biol. 2017 Nov;174:234-241. doi: 10.1016/j.jsbmb.2017.09.020. Epub 2017 Sep 28.

PMID:
28964928
15.

The 9th International Countercurrent Chromatography Conference held at Dominican University, Chicago, USA, August 1-3, 2016.

Friesen JB, McAlpine JB, Chen SN, Pauli GF.

J Chromatogr A. 2017 Oct 20;1520:1-8. doi: 10.1016/j.chroma.2017.08.077. Epub 2017 Sep 19.

PMID:
28939232
16.

In Vitro Activities of Enantiopure and Racemic 1'-Acetoxychavicol Acetate against Clinical Isolates of Mycobacterium tuberculosis.

Warit S, Rukseree K, Prammananan T, Hongmanee P, Billamas P, Jaitrong S, Chaiprasert A, Jaki BU, Pauli GF, Franzblau SG, Palittapongarnpim P.

Sci Pharm. 2017 Sep 18;85(3). pii: E32. doi: 10.3390/scipharm85030032.

17.

A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus.

Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolić D, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O.

Phytomedicine. 2017 Oct 15;34:50-58. doi: 10.1016/j.phymed.2017.08.001. Epub 2017 Aug 2.

18.

DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.

Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF.

J Nat Prod. 2017 Aug 25;80(8):2284-2294. doi: 10.1021/acs.jnatprod.7b00284. Epub 2017 Aug 16.

19.

Biochemical characterization and anti-inflammatory properties of an isothiocyanate-enriched moringa (Moringa oleifera) seed extract.

Jaja-Chimedza A, Graf BL, Simmler C, Kim Y, Kuhn P, Pauli GF, Raskin I.

PLoS One. 2017 Aug 8;12(8):e0182658. doi: 10.1371/journal.pone.0182658. eCollection 2017.

20.

Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.

Li G, Simmler C, Chen L, Nikolic D, Chen SN, Pauli GF, van Breemen RB.

Eur J Pharm Sci. 2017 Nov 15;109:182-190. doi: 10.1016/j.ejps.2017.07.034. Epub 2017 Jul 31.

PMID:
28774812
21.

Stereochemistry of a Second Riolozane and Other Diterpenoids from Jatropha dioica.

Melchor-Martínez EM, Silva-Mares DA, Torres-López E, Waksman-Minsky N, Pauli GF, Chen SN, Niemitz M, Sánchez-Castellanos M, Toscano A, Cuevas G, Rivas-Galindo VM.

J Nat Prod. 2017 Aug 25;80(8):2252-2262. doi: 10.1021/acs.jnatprod.7b00193. Epub 2017 Aug 3.

22.

Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A.

Simmler C, Lankin DC, Nikolić D, van Breemen RB, Pauli GF.

Fitoterapia. 2017 Sep;121:6-15. doi: 10.1016/j.fitote.2017.06.017. Epub 2017 Jun 21.

23.

Curcumin May (Not) Defy Science.

Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA.

ACS Med Chem Lett. 2017 May 11;8(5):467-470. doi: 10.1021/acsmedchemlett.7b00139. eCollection 2017 May 11. No abstract available.

24.

Sweet spot matching: A thin-layer chromatography-based countercurrent solvent system selection strategy.

Liu Y, Friesen JB, Grzelak EM, Fan Q, Tang T, Durić K, Jaki BU, McAlpine JB, Franzblau SG, Chen SN, Pauli GF.

J Chromatogr A. 2017 Jun 30;1504:46-54. doi: 10.1016/j.chroma.2017.04.055. Epub 2017 Apr 27.

25.

Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations.

AbouZid SF, Ahmed HS, Moawad AS, Owis AI, Chen SN, Nachtergael A, McAlpine JB, Brent Friesen J, Pauli GF.

Fitoterapia. 2017 Jun;119:175-184. doi: 10.1016/j.fitote.2017.04.002. Epub 2017 Apr 6.

26.

Oligomeric proanthocyanidins released from dentin induce regenerative dental pulp cell response.

Kulakowski D, Leme-Kraus AA, Nam JW, McAlpine J, Chen SN, Pauli GF, Ravindran S, Bedran-Russo AK.

Acta Biomater. 2017 Jun;55:262-270. doi: 10.1016/j.actbio.2017.03.051. Epub 2017 Mar 29.

27.

Absolute Configuration of Native Oligomeric Proanthocyanidins with Dentin Biomodification Potency.

Nam JW, Phansalkar RS, Lankin DC, McAlpine JB, Leme-Kraus AA, Vidal CM, Gan LS, Bedran-Russo A, Chen SN, Pauli GF.

J Org Chem. 2017 Feb 3;82(3):1316-1329. doi: 10.1021/acs.joc.6b02161. Epub 2017 Jan 18.

28.

The Essential Medicinal Chemistry of Curcumin.

Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA.

J Med Chem. 2017 Mar 9;60(5):1620-1637. doi: 10.1021/acs.jmedchem.6b00975. Epub 2017 Jan 11. Review.

29.

Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract.

Phansalkar RS, Simmler C, Bisson J, Chen SN, Lankin DC, McAlpine JB, Niemitz M, Pauli GF.

J Nat Prod. 2017 Mar 24;80(3):634-647. doi: 10.1021/acs.jnatprod.6b00923. Epub 2017 Jan 9.

30.

Biostability of the Proanthocyanidins-Dentin Complex and Adhesion Studies.

Leme-Kraus AA, Aydin B, Vidal CM, Phansalkar RM, Nam JW, McAlpine J, Pauli GF, Chen S, Bedran-Russo AK.

J Dent Res. 2017 Apr;96(4):406-412. doi: 10.1177/0022034516680586. Epub 2016 Dec 7.

31.

Effect of Bioactive Primers on Bacterial-Induced Secondary Caries at the Tooth-Resin Interface.

Kim GE, Leme-Kraus AA, Phansalkar R, Viana G, Wu C, Chen SN, Pauli GF, Bedran-Russo A.

Oper Dent. 2017 Mar/Apr;42(2):196-202. doi: 10.2341/16-107-L. Epub 2016 Nov 28.

32.

Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources.

Grzelak EM, Hwang C, Cai G, Nam JW, Choules MP, Gao W, Lankin DC, McAlpine JB, Mulugeta SG, Napolitano JG, Suh JW, Yang SH, Cheng J, Lee H, Kim JY, Cho SH, Pauli GF, Franzblau SG, Jaki BU.

ACS Infect Dis. 2016 Apr 8;2(4):294-301. Epub 2016 Feb 23.

33.

Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation.

Wang S, Dunlap TL, Howell CE, Mbachu OC, Rue EA, Phansalkar R, Chen SN, Pauli GF, Dietz BM, Bolton JL.

Chem Res Toxicol. 2016 Jul 18;29(7):1142-50. doi: 10.1021/acs.chemrestox.6b00112. Epub 2016 Jun 22.

34.

Silybum marianum pericarp yields enhanced silymarin products.

AbouZid SF, Chen SN, McAlpine JB, Friesen JB, Pauli GF.

Fitoterapia. 2016 Jul;112:136-43. doi: 10.1016/j.fitote.2016.05.012. Epub 2016 May 24.

35.

Dissemination of original NMR data enhances reproducibility and integrity in chemical research.

Bisson J, Simmler C, Chen SN, Friesen JB, Lankin DC, McAlpine JB, Pauli GF.

Nat Prod Rep. 2016 Aug 25;33(9):1028-33. doi: 10.1039/c6np00022c.

36.

Silymarin content in Silybum marianum populations growing in Egypt.

AbouZid SF, Chen SN, Pauli GF.

Ind Crops Prod. 2016 May;83:729-737. Epub 2016 Jan 5.

37.

Holistic Analysis Enhances the Description of Metabolic Complexity in Dietary Natural Products.

Simmler C, Kulakowski D, Lankin DC, McAlpine JB, Chen SN, Pauli GF.

Adv Nutr. 2016 Jan;7(1):179-89. Review.

38.

Countercurrent assisted quantitative recovery of metabolites from plant-associated natural deep eutectic solvents.

Liu Y, Garzon J, Friesen JB, Zhang Y, McAlpine JB, Lankin DC, Chen SN, Pauli GF.

Fitoterapia. 2016 Jul;112:30-37. doi: 10.1016/j.fitote.2016.04.019. Epub 2016 Apr 23.

39.

Computer-assisted 1 H NMR analysis of the anti-tuberculosis drug lead ecumicin.

Gao W, Napolitano JG, Lankin DC, Kim JY, Jin YY, Lee H, Suh JW, Chen SN, Pauli GF.

Magn Reson Chem. 2017 Mar;55(3):239-244. doi: 10.1002/mrc.4425. Epub 2016 Apr 19. No abstract available.

40.

Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches.

Simmler C, Chen SN, Anderson J, Lankin DC, Phansalkar R, Krause E, Dietz B, Bolton JL, Nikolic D, van Breemen RB, Pauli GF.

HerbalGram. 2016 Spring;109:60-64.

41.

Toward Structural Correctness: Aquatolide and the Importance of 1D Proton NMR FID Archiving.

Pauli GF, Niemitz M, Bisson J, Lodewyk MW, Soldi C, Shaw JT, Tantillo DJ, Saya JM, Vos K, Kleinnijenhuis RA, Hiemstra H, Chen SN, McAlpine JB, Lankin DC, Friesen JB.

J Org Chem. 2016 Feb 5;81(3):878-89. doi: 10.1021/acs.joc.5b02456. Epub 2016 Jan 26.

42.

Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa.

Imai A, Lankin DC, Nikolić D, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen SN, Pauli GF.

J Nat Prod. 2016 Mar 25;79(3):541-54. doi: 10.1021/acs.jnatprod.5b00927. Epub 2016 Jan 13.

43.

The Generally Useful Estimate of Solvent Systems (GUESS) method enables the rapid purification of methylpyridoxine regioisomers by countercurrent chromatography.

Liu Y, Friesen JB, Klein LL, McAlpine JB, Lankin DC, Pauli GF, Chen SN.

J Chromatogr A. 2015 Dec 24;1426:248-51. doi: 10.1016/j.chroma.2015.11.046. Epub 2015 Nov 17.

44.

Correction to Importance of Purity Evaluation and the Potential of Quantitative (1)H NMR as a Purity Assay.

Pauli GF, Chen SN, Simmler C, Lankin DC, Gödecke T, Jaki BU, Friesen JB, McAlpine JB, Napolitano JG.

J Med Chem. 2015 Nov 25;58(22):9061. doi: 10.1021/acs.jmedchem.5b01667. Epub 2015 Nov 17. No abstract available.

45.

Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

Bisson J, McAlpine JB, Friesen JB, Chen SN, Graham J, Pauli GF.

J Med Chem. 2016 Mar 10;59(5):1671-90. doi: 10.1021/acs.jmedchem.5b01009. Epub 2015 Oct 27. Review.

46.

Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.

Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolić D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Chem Res Toxicol. 2015 Nov 16;28(11):2130-41. doi: 10.1021/acs.chemrestox.5b00310. Epub 2015 Nov 5.

47.

Solvent System Selection Strategies in Countercurrent Separation.

Liu Y, Friesen JB, McAlpine JB, Pauli GF.

Planta Med. 2015 Nov;81(17):1582-91. doi: 10.1055/s-0035-1546246. Epub 2015 Sep 21. Review.

48.

Metabolite Profiling and Classification of DNA-Authenticated Licorice Botanicals.

Simmler C, Anderson JR, Gauthier L, Lankin DC, McAlpine JB, Chen SN, Pauli GF.

J Nat Prod. 2015 Aug 28;78(8):2007-22. doi: 10.1021/acs.jnatprod.5b00342. Epub 2015 Aug 5.

49.

Subtle Chemical Shifts Explain the NMR Fingerprints of Oligomeric Proanthocyanidins with High Dentin Biomodification Potency.

Nam JW, Phansalkar RS, Lankin DC, Bisson J, McAlpine JB, Leme AA, Vidal CM, Ramirez B, Niemitz M, Bedran-Russo A, Chen SN, Pauli GF.

J Org Chem. 2015 Aug 7;80(15):7495-507. doi: 10.1021/acs.joc.5b01082. Epub 2015 Jul 27.

50.

Countercurrent Separation of Natural Products: An Update.

Friesen JB, McAlpine JB, Chen SN, Pauli GF.

J Nat Prod. 2015 Jul 24;78(7):1765-96. doi: 10.1021/np501065h. Epub 2015 Jul 15. Review.

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