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Items: 1 to 50 of 548

1.

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense.

Huang Y, Mao K, Chen X, Sun MA, Kawabe T, Li W, Usher N, Zhu J, Urban JF Jr, Paul WE, Germain RN.

Science. 2018 Jan 5;359(6371):114-119. doi: 10.1126/science.aam5809.

PMID:
29302015
2.

Memory-phenotype CD4+ T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function.

Kawabe T, Jankovic D, Kawabe S, Huang Y, Lee PH, Yamane H, Zhu J, Sher A, Germain RN, Paul WE.

Sci Immunol. 2017 Jun 16;2(12). pii: eaam9304. doi: 10.1126/sciimmunol.aam9304.

3.

Role of CD4 T cell helper subsets in immune response and deviation of CD8 T cells in mice.

Hogg A, Sui Y, Ben-Sasson SZ, Paul WE, Berzofsky JA.

Eur J Immunol. 2017 Dec;47(12):2059-2069. doi: 10.1002/eji.201747091. Epub 2017 Aug 28.

PMID:
28741316
4.

PD-1 regulates KLRG1+ group 2 innate lymphoid cells.

Taylor S, Huang Y, Mallett G, Stathopoulou C, Felizardo TC, Sun MA, Martin EL, Zhu N, Woodward EL, Elias MS, Scott J, Reynolds NJ, Paul WE, Fowler DH, Amarnath S.

J Exp Med. 2017 Jun 5;214(6):1663-1678. doi: 10.1084/jem.20161653. Epub 2017 May 10.

5.

IL-7Rα Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin.

Kummola L, Ortutay Z, Chen X, Caucheteux S, Hämäläinen S, Aittomäki S, Yagi R, Zhu J, Pesu M, Paul WE, Junttila IS.

J Immunol. 2017 May 15;198(10):3909-3918. doi: 10.4049/jimmunol.1600753. Epub 2017 Apr 12.

6.

IL-4 Haploinsufficiency Specifically Impairs IgE Responses against Allergens in Mice.

Robinson MJ, Prout M, Mearns H, Kyle R, Camberis M, Forbes-Blom EE, Paul WE, Allen CD, Le Gros G.

J Immunol. 2017 Mar 1;198(5):1815-1822. doi: 10.4049/jimmunol.1601434. Epub 2017 Jan 23.

7.

Cytokine regulation of lung Th17 response to airway immunization using LPS adjuvant.

Caucheteux SM, Hu-Li J, Mohammed RN, Ager A, Paul WE.

Mucosal Immunol. 2017 Mar;10(2):361-372. doi: 10.1038/mi.2016.54. Epub 2016 Jun 22.

8.

IL-1β enhances inflammatory TH2 differentiation.

Caucheteux SM, Hu-Li J, Guo L, Bhattacharyya N, Crank M, Collins MT, Paul WE.

J Allergy Clin Immunol. 2016 Sep;138(3):898-901.e4. doi: 10.1016/j.jaci.2016.02.033. Epub 2016 Apr 19. No abstract available.

9.

B Cells Negatively Regulate the Establishment of CD49b(+)T-bet(+) Resting Memory T Helper Cells in the Bone Marrow.

Hojyo S, Sarkander J, Männe C, Mursell M, Hanazawa A, Zimmel D, Zhu J, Paul WE, Fillatreau S, Löhning M, Radbruch A, Tokoyoda K.

Front Immunol. 2016 Feb 2;7:26. doi: 10.3389/fimmu.2016.00026. eCollection 2016.

10.

Innate immunological function of TH2 cells in vivo.

Guo L, Huang Y, Chen X, Hu-Li J, Urban JF Jr, Paul WE.

Nat Immunol. 2015 Oct;16(10):1051-9. doi: 10.1038/ni.3244. Epub 2015 Aug 31.

11.

Inflammatory group 2 innate lymphoid cells.

Huang Y, Paul WE.

Int Immunol. 2016 Jan;28(1):23-8. doi: 10.1093/intimm/dxv044. Epub 2015 Aug 1. Review.

12.

History of interleukin-4.

Paul WE.

Cytokine. 2015 Sep;75(1):3-7. doi: 10.1016/j.cyto.2015.01.038. Epub 2015 Mar 23. Review.

13.

Dynamic tuning of lymphocytes: physiological basis, mechanisms, and function.

Grossman Z, Paul WE.

Annu Rev Immunol. 2015;33:677-713. doi: 10.1146/annurev-immunol-032712-100027. Epub 2015 Feb 6. Review.

PMID:
25665077
14.

Individual T helper cells have a quantitative cytokine memory.

Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M.

Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018. Epub 2014 Dec 25.

15.

TSLP expression: analysis with a ZsGreen TSLP reporter mouse.

Dewas C, Chen X, Honda T, Junttila I, Linton J, Udey MC, Porcella SF, Sturdevant DE, Feigenbaum L, Koo L, Williams J, Paul WE.

J Immunol. 2015 Feb 1;194(3):1372-80. doi: 10.4049/jimmunol.1400519. Epub 2014 Dec 24.

16.

IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.

Huang Y, Guo L, Qiu J, Chen X, Hu-Li J, Siebenlist U, Williamson PR, Urban JF Jr, Paul WE.

Nat Immunol. 2015 Feb;16(2):161-9. doi: 10.1038/ni.3078. Epub 2014 Dec 22.

17.

Pathogen-sensing and regulatory T cells: integrated regulators of immune responses.

Paul WE, Grossman Z.

Cancer Immunol Res. 2014 Jun;2(6):503-9. doi: 10.1158/2326-6066.CIR-14-0046.

18.

The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells.

Meylan F, Hawley ET, Barron L, Barlow JL, Penumetcha P, Pelletier M, Sciumè G, Richard AC, Hayes ET, Gomez-Rodriguez J, Chen X, Paul WE, Wynn TA, McKenzie AN, Siegel RM.

Mucosal Immunol. 2014 Jul;7(4):958-68. doi: 10.1038/mi.2013.114. Epub 2013 Dec 25.

19.

Endless fascination.

Paul WE.

Annu Rev Immunol. 2014;32:1-24. doi: 10.1146/annurev-immunol-032713-120247. Epub 2013 Oct 23.

PMID:
24161002
20.

Pathogen-sensing, regulatory T cells, and responsiveness-tuning collectively regulate foreign- and self-antigen mediated T-cell responses.

Paul WE, Milner JD, Grossman Z.

Cold Spring Harb Symp Quant Biol. 2013;78:265-76. doi: 10.1101/sqb.2013.78.020198. Epub 2013 Oct 7. Review.

PMID:
24100584
21.

IL-1β strikingly enhances antigen-driven CD4 and CD8 T-cell responses.

Ben-Sasson SZ, Wang K, Cohen J, Paul WE.

Cold Spring Harb Symp Quant Biol. 2013;78:117-24. doi: 10.1101/sqb.2013.78.021246. Epub 2013 Oct 3. Review.

PMID:
24092469
22.

Interleukin 1 enhances vaccine-induced antifungal T-helper 17 cells and resistance against Blastomyces dermatitidis infection.

Wüthrich M, LeBert V, Galles K, Hu-Li J, Ben-Sasson SZ, Paul WE, Klein BS.

J Infect Dis. 2013 Oct 1;208(7):1175-82. doi: 10.1093/infdis/jit283. Epub 2013 Jun 20.

23.

Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3.

Junttila IS, Watson C, Kummola L, Chen X, Hu-Li J, Guo L, Yagi R, Paul WE.

J Allergy Clin Immunol. 2013 Sep;132(3):704-712.e10. doi: 10.1016/j.jaci.2013.03.033. Epub 2013 May 14.

24.

Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling.

Guo L, Martens C, Bruno D, Porcella SF, Yamane H, Caucheteux SM, Zhu J, Paul WE.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):E1849-56. doi: 10.1073/pnas.1305070110. Epub 2013 Apr 29.

25.

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.

Roediger B, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St Groth B, Grimbaldeston MA, Le Gros G, Weninger W.

Nat Immunol. 2013 Jun;14(6):564-73. doi: 10.1038/ni.2584. Epub 2013 Apr 21.

26.

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells.

Ben-Sasson SZ, Hogg A, Hu-Li J, Wingfield P, Chen X, Crank M, Caucheteux S, Ratner-Hurevich M, Berzofsky JA, Nir-Paz R, Paul WE.

J Exp Med. 2013 Mar 11;210(3):491-502. doi: 10.1084/jem.20122006. Epub 2013 Mar 4.

27.

Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.

Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T.

Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011.

28.

Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets.

Yamane H, Paul WE.

Immunol Rev. 2013 Mar;252(1):12-23. doi: 10.1111/imr.12032. Review. Erratum in: Immunol Rev. 2013 Sep;255(1):275.

29.

Pillars article: Identification of a T cell-derived B cell growth factor distinct from interleukin 2. J. Exp. Med. 1982. 155: 914-923.

Howard M, Farrar J, Hilfiker M, Johnson B, Takatsu K, Hamaoka T, Paul WE.

J Immunol. 2013 Feb 1;190(3):864-73. No abstract available.

30.

Analysis of naïve lung CD4 T cells provides evidence of functional lung to lymph node migration.

Caucheteux SM, Torabi-Parizi P, Paul WE.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1821-6. doi: 10.1073/pnas.1221306110. Epub 2013 Jan 14.

31.

Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.

Junttila IS, Creusot RJ, Moraga I, Bates DL, Wong MT, Alonso MN, Suhoski MM, Lupardus P, Meier-Schellersheim M, Engleman EG, Utz PJ, Fathman CG, Paul WE, Garcia KC.

Nat Chem Biol. 2012 Dec;8(12):990-8. doi: 10.1038/nchembio.1096. Epub 2012 Oct 28.

32.

Cytokines of the γ(c) family control CD4+ T cell differentiation and function.

Yamane H, Paul WE.

Nat Immunol. 2012 Nov;13(11):1037-44. doi: 10.1038/ni.2431. Epub 2012 Oct 18. Review.

33.

The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses.

Zhu J, Jankovic D, Oler AJ, Wei G, Sharma S, Hu G, Guo L, Yagi R, Yamane H, Punkosdy G, Feigenbaum L, Zhao K, Paul WE.

Immunity. 2012 Oct 19;37(4):660-73. doi: 10.1016/j.immuni.2012.09.007. Epub 2012 Oct 4.

34.

Cytokine-induced cytokine production by conventional and innate lymphoid cells.

Guo L, Junttila IS, Paul WE.

Trends Immunol. 2012 Dec;33(12):598-606. doi: 10.1016/j.it.2012.07.006. Epub 2012 Sep 5. Review.

35.

Memory CD4+ T cells: fate determination, positive feedback and plasticity.

Yamane H, Paul WE.

Cell Mol Life Sci. 2012 May;69(10):1577-83. doi: 10.1007/s00018-012-0966-9. Epub 2012 Apr 6. Review.

36.

Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions.

Do JS, Foucras G, Kamada N, Schenk AF, Shaw M, Nuñez G, Paul WE, Min B.

Cell Immunol. 2012;272(2):117-23. doi: 10.1016/j.cellimm.2011.11.002. Epub 2011 Nov 25.

37.

Bridging innate and adaptive immunity.

Paul WE.

Cell. 2011 Dec 9;147(6):1212-5. doi: 10.1016/j.cell.2011.11.036.

38.

Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells.

Younes SA, Punkosdy G, Caucheteux S, Chen T, Grossman Z, Paul WE.

PLoS Biol. 2011 Oct;9(10):e1001171. doi: 10.1371/journal.pbio.1001171. Epub 2011 Oct 11.

39.

GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice.

Wohlfert EA, Grainger JR, Bouladoux N, Konkel JE, Oldenhove G, Ribeiro CH, Hall JA, Yagi R, Naik S, Bhairavabhotla R, Paul WE, Bosselut R, Wei G, Zhao K, Oukka M, Zhu J, Belkaid Y.

J Clin Invest. 2011 Nov;121(11):4503-15. doi: 10.1172/JCI57456. Epub 2011 Oct 3.

40.

Baruj Benacerraf (1920-2011).

Germain RN, Paul WE.

Nature. 2011 Aug 31;477(7362):34. doi: 10.1038/477034a. No abstract available.

PMID:
21886149
41.

Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types.

Wei G, Abraham BJ, Yagi R, Jothi R, Cui K, Sharma S, Narlikar L, Northrup DL, Tang Q, Paul WE, Zhu J, Zhao K.

Immunity. 2011 Aug 26;35(2):299-311. doi: 10.1016/j.immuni.2011.08.007.

42.

IL-1 acts on T cells to enhance the magnitude of in vivo immune responses.

Ben-Sasson SZ, Caucheteux S, Crank M, Hu-Li J, Paul WE.

Cytokine. 2011 Oct;56(1):122-5. doi: 10.1016/j.cyto.2011.07.006. Epub 2011 Aug 16. Review.

43.

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation.

Yagi R, Zhu J, Paul WE.

Int Immunol. 2011 Jul;23(7):415-20. doi: 10.1093/intimm/dxr029. Epub 2011 Jun 1. Review.

44.

Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number.

Bocharov G, Quiel J, Luzyanina T, Alon H, Chiglintsev E, Chereshnev V, Meier-Schellersheim M, Paul WE, Grossman Z.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3318-23. doi: 10.1073/pnas.1019706108. Epub 2011 Feb 3.

45.

Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number.

Quiel J, Caucheteux S, Laurence A, Singh NJ, Bocharov G, Ben-Sasson SZ, Grossman Z, Paul WE.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3312-7. doi: 10.1073/pnas.1018525108. Epub 2011 Feb 3.

46.

Basophils are the major producers of IL-4 during primary helminth infection.

van Panhuys N, Prout M, Forbes E, Min B, Paul WE, Le Gros G.

J Immunol. 2011 Mar 1;186(5):2719-28. doi: 10.4049/jimmunol.1000940. Epub 2011 Jan 26.

47.

The classic: Contribution to the study of spinal surgery: one successful and one unsuccessful operation for removal of tumor. 1905.

Walton GL, Paul WE.

Clin Orthop Relat Res. 2011 Mar;469(3):635-8. doi: 10.1007/s11999-010-1664-2. No abstract available.

48.

Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.

Zhu J, Paul WE.

Immunol Rev. 2010 Nov;238(1):247-62. doi: 10.1111/j.1600-065X.2010.00951.x. Review. Erratum in: Immunol Rev. 2011 Mar;240(1):317.

49.

Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.

Khandanpour C, Sharif-Askari E, Vassen L, Gaudreau MC, Zhu J, Paul WE, Okayama T, Kosan C, Möröy T.

Blood. 2010 Dec 9;116(24):5149-61. doi: 10.1182/blood-2010-04-280305. Epub 2010 Sep 8.

50.

Regulation of microRNA expression and abundance during lymphopoiesis.

Kuchen S, Resch W, Yamane A, Kuo N, Li Z, Chakraborty T, Wei L, Laurence A, Yasuda T, Peng S, Hu-Li J, Lu K, Dubois W, Kitamura Y, Charles N, Sun HW, Muljo S, Schwartzberg PL, Paul WE, O'Shea J, Rajewsky K, Casellas R.

Immunity. 2010 Jun 25;32(6):828-39. doi: 10.1016/j.immuni.2010.05.009. Epub 2010 Jun 3.

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