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Items: 1 to 50 of 140

1.

Discovery of Amantamide, a Selective CXCR7 Agonist from Marine Cyanobacteria.

Liang X, Luo D, Yan JL, Rezaei MA, Salvador-Reyes LA, Gunasekera SP, Li C, Ye T, Paul VJ, Luesch H.

Org Lett. 2019 Mar 15;21(6):1622-1626. doi: 10.1021/acs.orglett.9b00163. Epub 2019 Feb 19.

PMID:
30779584
2.

Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria.

Luo D, Putra MY, Ye T, Paul VJ, Luesch H.

Mar Drugs. 2019 Feb 1;17(2). pii: E83. doi: 10.3390/md17020083.

3.

Chemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide Macrocycles.

Gunasekera SP, Meyer JL, Ding Y, Abboud KA, Luo D, Campbell JE, Angerhofer A, Goodsell JL, Raymundo LJ, Liu J, Ye T, Luesch H, Teplitski M, Paul VJ.

J Nat Prod. 2019 Jan 25;82(1):111-121. doi: 10.1021/acs.jnatprod.8b00804. Epub 2019 Jan 13.

4.

Isolation and Characterization of Anaephenes A-C, Alkylphenols from a Filamentous Cyanobacterium ( Hormoscilla sp., Oscillatoriales).

Brumley D, Spencer KA, Gunasekera SP, Sauvage T, Biggs J, Paul VJ, Luesch H.

J Nat Prod. 2018 Nov 29. doi: 10.1021/acs.jnatprod.8b00650. [Epub ahead of print]

PMID:
30489078
5.

Spatial and temporal shifts in the diet of the barnacle Amphibalanus eburneus within a subtropical estuary.

Freeman CJ, Janiak DS, Mossop M, Osman R, Paul VJ.

PeerJ. 2018 Aug 15;6:e5485. doi: 10.7717/peerj.5485. eCollection 2018.

6.

Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium.

Al-Awadhi FH, Gao B, Rezaei MA, Kwan JC, Li C, Ye T, Paul VJ, Luesch H.

J Med Chem. 2018 Jul 26;61(14):6364-6378. doi: 10.1021/acs.jmedchem.8b00885. Epub 2018 Jul 17.

PMID:
30015488
7.

Uncovering cryptic diversity of Lyngbya: the new tropical marine cyanobacterial genus Dapis (Oscillatoriales).

Engene N, Tronholm A, Paul VJ.

J Phycol. 2018 Aug;54(4):435-446. doi: 10.1111/jpy.12752. Epub 2018 Jun 25.

PMID:
29791035
8.

Discovery of new A- and B-type laxaphycins with synergistic anticancer activity.

Cai W, Matthew S, Chen QY, Paul VJ, Luesch H.

Bioorg Med Chem. 2018 May 15;26(9):2310-2319. doi: 10.1016/j.bmc.2018.03.022. Epub 2018 Mar 14.

PMID:
29606488
9.

A Complementary Chemical and Genomic Screening Approach for Druggable Targets in the Nrf2 Pathway and Small Molecule Inhibitors to Overcome Cancer Cell Drug Resistance.

Matthews JH, Liang X, Paul VJ, Luesch H.

ACS Chem Biol. 2018 May 18;13(5):1189-1199. doi: 10.1021/acschembio.7b01025. Epub 2018 Mar 22.

PMID:
29565554
10.

Interspecific Variation in Coral Settlement and Fertilization Success in Response to Hydrogen Peroxide Exposure.

Ross C, Fogarty ND, Ritson-Williams R, Paul VJ.

Biol Bull. 2017 Dec;233(3):206-218. doi: 10.1086/696215. Epub 2018 Feb 23.

PMID:
29553820
11.

Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer.

Al-Awadhi FH, Paul VJ, Luesch H.

Chembiochem. 2018 Apr 16;19(8):815-825. doi: 10.1002/cbic.201700627. Epub 2018 Mar 23.

PMID:
29405541
12.

Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing.

Cai W, Salvador-Reyes LA, Zhang W, Chen QY, Matthew S, Ratnayake R, Seo SJ, Dolles S, Gibson DJ, Paul VJ, Luesch H.

ACS Chem Biol. 2018 Jan 19;13(1):91-99. doi: 10.1021/acschembio.7b00827. Epub 2017 Dec 5.

13.

Bloom dynamics and chemical defenses of benthic cyanobacteria in the Indian River Lagoon, Florida.

Sneed JM, Meickle T, Engene N, Reed S, Gunasekera S, Paul VJ.

Harmful Algae. 2017 Nov;69:75-82. doi: 10.1016/j.hal.2017.10.002. Epub 2017 Oct 23.

PMID:
29122244
14.

Grassystatins D-F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer.

Al-Awadhi FH, Law BK, Paul VJ, Luesch H.

J Nat Prod. 2017 Nov 22;80(11):2969-2986. doi: 10.1021/acs.jnatprod.7b00551. Epub 2017 Oct 31.

15.

Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer.

Al-Awadhi FH, Salvador LA, Law BK, Paul VJ, Luesch H.

Mar Drugs. 2017 Sep 16;15(9). pii: E290. doi: 10.3390/md15090290.

16.

Declines in plant palatability from polar to tropical latitudes depend on herbivore and plant identity.

Demko AM, Amsler CD, Hay ME, Long JD, McClintock JB, Paul VJ, Sotka EE.

Ecology. 2017 Sep;98(9):2312-2321. doi: 10.1002/ecy.1918. Epub 2017 Aug 9.

17.

Comparative Metagenomics of the Polymicrobial Black Band Disease of Corals.

Meyer JL, Paul VJ, Raymundo LJ, Teplitski M.

Front Microbiol. 2017 Apr 18;8:618. doi: 10.3389/fmicb.2017.00618. eCollection 2017.

18.

Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges.

Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS.

Nat Chem Biol. 2017 May;13(5):537-543. doi: 10.1038/nchembio.2330. Epub 2017 Mar 20.

19.

Elevated Temperature and Allelopathy Impact Coral Recruitment.

Ritson-Williams R, Ross C, Paul VJ.

PLoS One. 2016 Dec 7;11(12):e0166581. doi: 10.1371/journal.pone.0166581. eCollection 2016.

20.

Caldoramide, a Modified Pentapeptide from the Marine Cyanobacterium Caldora penicillata.

Gunasekera SP, Imperial L, Garst C, Ratnayake R, Dang LH, Paul VJ, Luesch H.

J Nat Prod. 2016 Jul 22;79(7):1867-71. doi: 10.1021/acs.jnatprod.6b00203. Epub 2016 Jul 5.

21.

Epimicrobiota Associated with the Decay and Recovery of Orbicella Corals Exhibiting Dark Spot Syndrome.

Meyer JL, Rodgers JM, Dillard BA, Paul VJ, Teplitski M.

Front Microbiol. 2016 Jun 7;7:893. doi: 10.3389/fmicb.2016.00893. eCollection 2016.

22.

Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium.

Al-Awadhi FH, Ratnayake R, Paul VJ, Luesch H.

Bioorg Med Chem. 2016 Aug 1;24(15):3276-82. doi: 10.1016/j.bmc.2016.04.062. Epub 2016 Apr 30.

23.

Discovery, Total Synthesis and Key Structural Elements for the Immunosuppressive Activity of Cocosolide, a Symmetrical Glycosylated Macrolide Dimer from Marine Cyanobacteria.

Gunasekera SP, Li Y, Ratnayake R, Luo D, Lo J, Reibenspies JH, Xu Z, Clare-Salzler MJ, Ye T, Paul VJ, Luesch H.

Chemistry. 2016 Jun 6;22(24):8158-66. doi: 10.1002/chem.201600674. Epub 2016 May 3.

24.

Pitiamides A and B, Multifunctional Fatty Acid Amides from Marine Cyanobacteria.

Cai W, Matthews JH, Paul VJ, Luesch H.

Planta Med. 2016 Jun;82(9-10):897-902. doi: 10.1055/s-0042-105157. Epub 2016 May 2.

25.

Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.

El Gamal A, Agarwal V, Diethelm S, Rahman I, Schorn MA, Sneed JM, Louie GV, Whalen KE, Mincer TJ, Noel JP, Paul VJ, Moore BS.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3797-802. doi: 10.1073/pnas.1519695113. Epub 2016 Mar 21.

26.

Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer.

Bousquet MS, Ma JJ, Ratnayake R, Havre PA, Yao J, Dang NH, Paul VJ, Carney TJ, Dang LH, Luesch H.

ACS Chem Biol. 2016 May 20;11(5):1322-31. doi: 10.1021/acschembio.5b00860. Epub 2016 Mar 3.

27.

Correction to Caylobolide B, a Macrolactone from Symplostatin 1-Producing Marine Cyanobacteria Phormidium spp. from Florida.

Salvador LA, Paul VJ, Luesch H.

J Nat Prod. 2016 Feb 26;79(2):452. doi: 10.1021/acs.jnatprod.6b00120. Epub 2016 Feb 17. No abstract available.

PMID:
26885760
28.

Selection criteria for reconstructive surgery to correct mobile hand deformities in leprosy.

Govindasamy K, Das P, Paul VJ, Kumar J.

Lepr Rev. 2015 Sep;86(3):278-82. No abstract available.

PMID:
26665364
29.

Microbiome shifts and the inhibition of quorum sensing by Black Band Disease cyanobacteria.

Meyer JL, Gunasekera SP, Scott RM, Paul VJ, Teplitski M.

ISME J. 2016 May;10(5):1204-16. doi: 10.1038/ismej.2015.184. Epub 2015 Oct 23.

30.

Draft genome sequence of Halomonas meridiana R1t3 isolated from the surface microbiota of the Caribbean Elkhorn coral Acropora palmata.

Meyer JL, Dillard BA, Rodgers JM, Ritchie KB, Paul VJ, Teplitski M.

Stand Genomic Sci. 2015 Oct 7;10:75. doi: 10.1186/s40793-015-0069-y. eCollection 2015.

31.

Caldora penicillata gen. nov., comb. nov. (cyanobacteria), a pantropical marine species with biomedical relevance.

Engene N, Tronholm A, Salvador-Reyes LA, Luesch H, Paul VJ.

J Phycol. 2015 Aug;51(4):670-81.

32.

Amantelides A and B, Polyhydroxylated Macrolides with Differential Broad-Spectrum Cytotoxicity from a Guamanian Marine Cyanobacterium.

Salvador-Reyes LA, Sneed J, Paul VJ, Luesch H.

J Nat Prod. 2015 Aug 28;78(8):1957-62. doi: 10.1021/acs.jnatprod.5b00293. Epub 2015 Jul 23.

33.

Induction of Larval Settlement in the Reef Coral Porites astreoides by a Cultivated Marine Roseobacter Strain.

Sharp KH, Sneed JM, Ritchie KB, Mcdaniel L, Paul VJ.

Biol Bull. 2015 Apr;228(2):98-107.

PMID:
25920713
34.

Crustose coralline algal species host distinct bacterial assemblages on their surfaces.

Sneed JM, Ritson-Williams R, Paul VJ.

ISME J. 2015 Nov;9(11):2527-36. doi: 10.1038/ismej.2015.67. Epub 2015 Apr 28.

35.

Targeted natural products discovery from marine cyanobacteria using combined phylogenetic and mass spectrometric evaluation.

Salvador-Reyes LA, Engene N, Paul VJ, Luesch H.

J Nat Prod. 2015 Mar 27;78(3):486-92. doi: 10.1021/np500931q. Epub 2015 Jan 30.

36.

Complexity of naturally produced polybrominated diphenyl ethers revealed via mass spectrometry.

Agarwal V, Li J, Rahman I, Borgen M, Aluwihare LI, Biggs JS, Paul VJ, Moore BS.

Environ Sci Technol. 2015 Feb 3;49(3):1339-46. doi: 10.1021/es505440j. Epub 2015 Jan 21.

37.

Carriebowlinol, an antimicrobial tetrahydroquinolinol from an assemblage of marine cyanobacteria containing a novel taxon.

Soares AR, Engene N, Gunasekera SP, Sneed JM, Paul VJ.

J Nat Prod. 2015 Mar 27;78(3):534-8. doi: 10.1021/np500598x. Epub 2014 Dec 23.

PMID:
25536090
38.

Marine chemical ecology in benthic environments.

Puglisi MP, Sneed JM, Sharp KH, Ritson-Williams R, Paul VJ.

Nat Prod Rep. 2014 Nov;31(11):1510-53. doi: 10.1039/c4np00017j. Review.

PMID:
25070776
39.

Interactions between the tropical sea anemone Aiptasia pallida and Serratia marcescens, an opportunistic pathogen of corals.

Krediet CJ, Meyer JL, Gimbrone N, Yanong R, Berzins I, Alagely A, Castro H, Ritchie KB, Paul VJ, Teplitski M.

Environ Microbiol Rep. 2014 Jun;6(3):287-92. doi: 10.1111/1758-2229.12151. Epub 2014 Mar 25.

PMID:
24983533
40.

Community shifts in the surface microbiomes of the coral Porites astreoides with unusual lesions.

Meyer JL, Paul VJ, Teplitski M.

PLoS One. 2014 Jun 17;9(6):e100316. doi: 10.1371/journal.pone.0100316. eCollection 2014.

41.

The chemical cue tetrabromopyrrole from a biofilm bacterium induces settlement of multiple Caribbean corals.

Sneed JM, Sharp KH, Ritchie KB, Paul VJ.

Proc Biol Sci. 2014 Jul 7;281(1786). pii: 20133086. doi: 10.1098/rspb.2013.3086.

42.

Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation.

Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H.

Chembiochem. 2014 Apr 14;15(6):799-804. doi: 10.1002/cbic.201300762. Epub 2014 Mar 3.

44.

Five chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. nov. (Oscillatoriales, Cyanoprokaryota).

Engene N, Paul VJ, Byrum T, Gerwick WH, Thor A, Ellisman MH.

J Phycol. 2013 Dec;49(6):1095-106. doi: 10.1111/jpy.12115. Epub 2013 Oct 21.

PMID:
27007630
45.

Cultivated sea lettuce is a multiorgan protector from oxidative and inflammatory stress by enhancing the endogenous antioxidant defense system.

Ratnayake R, Liu Y, Paul VJ, Luesch H.

Cancer Prev Res (Phila). 2013 Sep;6(9):989-99. doi: 10.1158/1940-6207.CAPR-13-0014.

46.

First identification of 5,11-dideoxytetrodotoxin in marine animals, and characterization of major fragment ions of tetrodotoxin and its analogs by high resolution ESI-MS/MS.

Yotsu-Yamashita M, Abe Y, Kudo Y, Ritson-Williams R, Paul VJ, Konoki K, Cho Y, Adachi M, Imazu T, Nishikawa T, Isobe M.

Mar Drugs. 2013 Aug 6;11(8):2799-813. doi: 10.3390/md11082799.

47.

Modular strategies for structure and function employed by marine cyanobacteria: characterization and synthesis of pitinoic acids.

Montaser R, Paul VJ, Luesch H.

Org Lett. 2013 Aug 16;15(16):4050-3. doi: 10.1021/ol401396u. Epub 2013 Aug 5.

48.

Quorum-sensing inhibitory compounds from extremophilic microorganisms isolated from a hypersaline cyanobacterial mat.

Abed RM, Dobretsov S, Al-Fori M, Gunasekera SP, Sudesh K, Paul VJ.

J Ind Microbiol Biotechnol. 2013 Jul;40(7):759-72. doi: 10.1007/s10295-013-1276-4. Epub 2013 May 5.

PMID:
23645384
49.
50.

Coral-associated micro-organisms and their roles in promoting coral health and thwarting diseases.

Krediet CJ, Ritchie KB, Paul VJ, Teplitski M.

Proc Biol Sci. 2013 Jan 30;280(1755):20122328. doi: 10.1098/rspb.2012.2328. Print 2013 Mar 22. Review.

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