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Items: 1 to 50 of 59

1.

Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes.

Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8731-E8740. doi: 10.1073/pnas.1714385114. Epub 2017 Sep 25.

2.

Computer-aided vaccine designing approach against fish pathogens Edwardsiella tarda and Flavobacterium columnare using bioinformatics softwares.

Mahendran R, Jeyabaskar S, Sitharaman G, Michael RD, Paul AV.

Drug Des Devel Ther. 2016 May 23;10:1703-14. doi: 10.2147/DDDT.S95691. eCollection 2016.

3.

A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPase Causes Conditional Defects in Encapsidation and Uncoating.

Asare E, Mugavero J, Jiang P, Wimmer E, Paul AV.

J Virol. 2016 Jun 24;90(14):6174-6186. doi: 10.1128/JVI.02877-15. Print 2016 Jul 15.

4.

Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses.

Schein CH, Ye M, Paul AV, Oberste MS, Chapman N, van der Heden van Noort GJ, Filippov DV, Choi KH.

Virology. 2015 Oct;484:80-5. doi: 10.1016/j.virol.2015.05.016. Epub 2015 Jun 11.

5.

Initiation of protein-primed picornavirus RNA synthesis.

Paul AV, Wimmer E.

Virus Res. 2015 Aug 3;206:12-26. doi: 10.1016/j.virusres.2014.12.028. Epub 2015 Jan 12. Review.

6.

Picornavirus morphogenesis.

Jiang P, Liu Y, Ma HC, Paul AV, Wimmer E.

Microbiol Mol Biol Rev. 2014 Sep;78(3):418-37. doi: 10.1128/MMBR.00012-14. Review.

7.

An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses.

Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P.

PLoS Pathog. 2014 Apr 10;10(4):e1004052. doi: 10.1371/journal.ppat.1004052. eCollection 2014 Apr.

8.

A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis.

Wang C, Ma HC, Wimmer E, Jiang P, Paul AV.

J Gen Virol. 2014 Jun;95(Pt 6):1255-65. doi: 10.1099/vir.0.062497-0. Epub 2014 Feb 20.

9.

Dyslipidaemia among type 2 diabetes mellitus patients in a rural hospital in Erode district, Tamilnadu.

Subburam R, Manohar CR, Subramaniyam P, Sachithanantham S, Paul AV, Sankarapandian M.

J Indian Med Assoc. 2013 Jan;111(1):10-3.

PMID:
24000500
10.

Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design.

Song Y, Liu Y, Ward CB, Mueller S, Futcher B, Skiena S, Paul AV, Wimmer E.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14301-7. doi: 10.1073/pnas.1211484109. Epub 2012 Aug 10.

11.

Alanine scanning of poliovirus 2CATPase reveals new genetic evidence that capsid protein/2CATPase interactions are essential for morphogenesis.

Wang C, Jiang P, Sand C, Paul AV, Wimmer E.

J Virol. 2012 Sep;86(18):9964-75. doi: 10.1128/JVI.00914-12. Epub 2012 Jul 3.

12.

Evolution of poliovirus defective interfering particles expressing Gaussia luciferase.

Song Y, Paul AV, Wimmer E.

J Virol. 2012 Feb;86(4):1999-2010. doi: 10.1128/JVI.05871-11. Epub 2011 Dec 7.

13.

Synthetic poliovirus and other designer viruses: what have we learned from them?

Wimmer E, Paul AV.

Annu Rev Microbiol. 2011;65:583-609. doi: 10.1146/annurev-micro-090110-102957. Review.

PMID:
21756105
15.

Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis.

Liu Y, Wang C, Mueller S, Paul AV, Wimmer E, Jiang P.

PLoS Pathog. 2010 Aug 26;6(8):e1001066. doi: 10.1371/journal.ppat.1001066.

16.

Cis-acting RNA elements in human and animal plus-strand RNA viruses.

Liu Y, Wimmer E, Paul AV.

Biochim Biophys Acta. 2009 Sep-Oct;1789(9-10):495-517. doi: 10.1016/j.bbagrm.2009.09.007. Epub 2009 Sep 23. Review.

17.

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

Graci JD, Harki DA, Korneeva VS, Edathil JP, Too K, Franco D, Smidansky ED, Paul AV, Peterson BR, Brown DM, Loakes D, Cameron CE.

J Virol. 2007 Oct;81(20):11256-66. Epub 2007 Aug 8.

18.

Complete protein linkage map between the P2 and P3 non-structural proteins of poliovirus.

Yin J, Liu Y, Wimmer E, Paul AV.

J Gen Virol. 2007 Aug;88(Pt 8):2259-67.

PMID:
17622630
20.

Membrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication.

Fujita K, Krishnakumar SS, Franco D, Paul AV, London E, Wimmer E.

Biochemistry. 2007 May 1;46(17):5185-99. Epub 2007 Apr 7.

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24.

Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro.

Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV.

J Virol. 2005 May;79(10):6358-67.

25.
26.

A "slide-back" mechanism for the initiation of protein-primed RNA synthesis by the RNA polymerase of poliovirus.

Paul AV, Yin J, Mugavero J, Rieder E, Liu Y, Wimmer E.

J Biol Chem. 2003 Nov 7;278(45):43951-60. Epub 2003 Aug 22.

28.

Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus.

Paul AV, Peters J, Mugavero J, Yin J, van Boom JH, Wimmer E.

J Virol. 2003 Jan;77(2):891-904.

29.

Vaccines should be kept even if polio is wiped out.

Cello J, Paul AV, Wimmer E.

Nature. 2002 Aug 29;418(6901):915. No abstract available.

PMID:
12198515
30.

Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template.

Cello J, Paul AV, Wimmer E.

Science. 2002 Aug 9;297(5583):1016-8. Epub 2002 Jul 11.

31.

Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation.

Pathak HB, Ghosh SK, Roberts AW, Sharma SD, Yoder JD, Arnold JJ, Gohara DW, Barton DJ, Paul AV, Cameron CE.

J Biol Chem. 2002 Aug 30;277(35):31551-62. Epub 2002 Jun 19.

34.

Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation.

Rieder E, Paul AV, Kim DW, van Boom JH, Wimmer E.

J Virol. 2000 Nov;74(22):10371-80.

35.
36.
37.

Paradoxes of the replication of picornaviral genomes.

Agol VI, Paul AV, Wimmer E.

Virus Res. 1999 Aug;62(2):129-47. Review.

PMID:
10507323
38.
39.

Protein-primed RNA synthesis by purified poliovirus RNA polymerase.

Paul AV, van Boom JH, Filippov D, Wimmer E.

Nature. 1998 May 21;393(6682):280-4.

PMID:
9607767
40.

Molecular dissection of the multifunctional poliovirus RNA-binding protein 3AB.

Xiang W, Cuconati A, Paul AV, Cao X, Wimmer E.

RNA. 1995 Nov;1(9):892-904.

41.

Studies with poliovirus polymerase 3Dpol. Stimulation of poly(U) synthesis in vitro by purified poliovirus protein 3AB.

Paul AV, Cao X, Harris KS, Lama J, Wimmer E.

J Biol Chem. 1994 Nov 18;269(46):29173-81.

42.

Stimulation of poliovirus proteinase 3Cpro-related proteolysis by the genome-linked protein VPg and its precursor 3AB.

Molla A, Harris KS, Paul AV, Shin SH, Mugavero J, Wimmer E.

J Biol Chem. 1994 Oct 28;269(43):27015-20.

43.
44.

Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C.

Paul AV, Molla A, Wimmer E.

Virology. 1994 Feb 15;199(1):188-99.

PMID:
8116242
45.
46.

Studies on dicistronic polioviruses implicate viral proteinase 2Apro in RNA replication.

Molla A, Paul AV, Schmid M, Jang SK, Wimmer E.

Virology. 1993 Oct;196(2):739-47.

PMID:
8396807
47.
48.

In vitro synthesis of poliovirus.

Molla A, Paul AV, Wimmer E.

Dev Biol Stand. 1993;78:39-53.

PMID:
8388831
49.

Cardioviral internal ribosomal entry site is functional in a genetically engineered dicistronic poliovirus.

Molla A, Jang SK, Paul AV, Reuer Q, Wimmer E.

Nature. 1992 Mar 19;356(6366):255-7.

PMID:
1313153
50.

Cell-free, de novo synthesis of poliovirus.

Molla A, Paul AV, Wimmer E.

Science. 1991 Dec 13;254(5038):1647-51.

PMID:
1661029

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