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Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators.

Paudel S, Shrestha A, Cho P, Shrestha R, Kim Y, Lee T, Kim JH, Jeong TC, Lee ES, Lee S.

Pharmaceutics. 2019 Sep 16;11(9). pii: E479. doi: 10.3390/pharmaceutics11090479.


Induced Plant Defenses Against Herbivory in Cultivated and Wild Tomato.

Paudel S, Lin PA, Foolad MR, Ali JG, Rajotte EG, Felton GW.

J Chem Ecol. 2019 Aug;45(8):693-707. doi: 10.1007/s10886-019-01090-4. Epub 2019 Aug 1.


Anti-Inflammatory and Anti-Arthritic Efficacies of an Indian Traditional Herbo-Mineral Medicine "Divya Amvatari Ras" in Collagen Antibody-Induced Arthritis (CAIA) Mouse Model Through Modulation of IL-6/IL-1β/TNF-α/NFκB Signaling.

Balkrishna A, Sakat SS, Joshi K, Paudel S, Joshi D, Joshi K, Ranjan R, Gupta A, Bhattacharya K, Varshney A.

Front Pharmacol. 2019 Jul 1;10:659. doi: 10.3389/fphar.2019.00659. eCollection 2019.


Human TB threat to wild elephants.

Paudel S, Tsubota T, Mikota SK.

Nature. 2019 Jul;571(7764):174. doi: 10.1038/d41586-019-02114-5. No abstract available.


Physical activity participation and the risk of chronic diseases among South Asian adults: a systematic review and meta-analysis.

Paudel S, Owen AJ, Owusu-Addo E, Smith BJ.

Sci Rep. 2019 Jul 5;9(1):9771. doi: 10.1038/s41598-019-46154-3.


Identification of sulfonyl-loxoprofen as novel phase 2 conjugate in rat.

Shrestha R, Paudel S, Cho P, Shrestha A, Jeong TC, Lee ES, Lee T, Lee S.

Biopharm Drug Dispos. 2019 Jul;40(7):234-241. doi: 10.1002/bdd.2196. Epub 2019 Jul 19.


Development of a robust, field-deployable loop-mediated isothermal amplification (LAMP) assay for specific detection of potato pathogen Dickeya dianthicola targeting a unique genomic region.

Ocenar J, Arizala D, Boluk G, Dhakal U, Gunarathne S, Paudel S, Dobhal S, Arif M.

PLoS One. 2019 Jun 24;14(6):e0218868. doi: 10.1371/journal.pone.0218868. eCollection 2019.


Himalayan honey loaded iron oxide nanoparticles: synthesis, characterization and study of antioxidant and antimicrobial activities.

Neupane BP, Chaudhary D, Paudel S, Timsina S, Chapagain B, Jamarkattel N, Tiwari BR.

Int J Nanomedicine. 2019 May 15;14:3533-3541. doi: 10.2147/IJN.S196671. eCollection 2019.


Herbo-mineral formulation 'Ashwashila' attenuates rheumatoid arthritis symptoms in collagen-antibody-induced arthritis (CAIA) mice model.

Balkrishna A, Sakat SS, Joshi K, Paudel S, Joshi D, Joshi K, Ranjan R, Gupta A, Bhattacharya K, Varshney A.

Sci Rep. 2019 May 29;9(1):8025. doi: 10.1038/s41598-019-44485-9.


Mixed Mycobacterium tuberculosis Lineage Infection in 2 Elephants, Nepal.

Paudel S, Nakajima C, Mikota SK, Gairhe KP, Maharjan B, Subedi S, Poudel A, Sashika M, Shimozuru M, Suzuki Y, Tsubota T.

Emerg Infect Dis. 2019 May;25(5):1031-1032. doi: 10.3201/eid2505.181898.


Calcium Activity Dynamics Correlate with Neuronal Phenotype at a Single Cell Level and in a Threshold-Dependent Manner.

Paudel S, Ablondi E, Sehdev M, Marken J, Halleran A, Rahman A, Kemper P, Saha MS.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1880. doi: 10.3390/ijms20081880.


Cluster Formation and Entanglement in the Rheology of Antibody Solutions.

Ramallo N, Paudel S, Schmit J.

J Phys Chem B. 2019 May 9;123(18):3916-3923. doi: 10.1021/acs.jpcb.9b01511. Epub 2019 Apr 25.


A Peptide Derived from Phosphoinositide 3-kinase Inhibits Endocytosis and Influenza Virus Infection.

Fujioka Y, Satoh AO, Horiuchi K, Fujioka M, Tsutsumi K, Sasaki J, Nepal P, Kashiwagi S, Paudel S, Nishide S, Nanbo A, Sasaki T, Ohba Y.

Cell Struct Funct. 2019 Apr 25;44(1):61-74. doi: 10.1247/csf.19001. Epub 2019 Mar 21.


Molecular Characterization of Colistin-Resistant Escherichia coli Isolated from Chickens: First Report from Nepal.

Joshi PR, Thummeepak R, Paudel S, Acharya M, Pradhan S, Banjara MR, Leungtongkam U, Sitthisak S.

Microb Drug Resist. 2019 Jul/Aug;25(6):846-854. doi: 10.1089/mdr.2018.0326. Epub 2019 Mar 15.


Echo dephasing and heat capacity from constrained and unconstrained dynamics of triiodothyronine nuclear receptor protein.

Lamichhane TR, Paudel S, Yadav BK, Lamichhane HP.

J Biol Phys. 2019 Mar;45(1):107-125. doi: 10.1007/s10867-018-9518-3. Epub 2019 Feb 27.


Evaluation of Risk Factors for Antipsychotic Polypharmacy in Inpatient Psychiatry Units of a Community Hospital: A Retrospective Analysis.

Paudel S, Dahal R, Mathias J, Arjyal S, Markovic L.

Community Ment Health J. 2019 Jul;55(5):750-754. doi: 10.1007/s10597-019-00381-0. Epub 2019 Feb 25.


Intravenous administration of multipotent stromal cells and bone allograft modification to enhance allograft healing.

Paudel S, Lee WH, Lee M, Zahoor T, Mitchell R, Yang SY, Zhao H, Schon L, Zhang Z.

Regen Med. 2019 Mar;14(3):199-211. doi: 10.2217/rme-2018-0063. Epub 2019 Feb 14.


Preparative Separation of Three Monoterpenes from Perilla frutescens var. crispa Using Centrifugal Partition Chromatography.

Nam B, Paudel SB, Kim JB, Jin CH, Lee D, Nam JW, Han AR.

Int J Anal Chem. 2019 Jan 9;2019:8751345. doi: 10.1155/2019/8751345. eCollection 2019.


CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3.

Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, DeCorte JA, Le JT, Cai S, Jeyaseelan S.

Blood. 2019 Mar 21;133(12):1335-1345. doi: 10.1182/blood-2018-10-878082. Epub 2019 Feb 5.


Tuberculosis threat in Asian elephants.

Paudel S, Mikota SK, Tsubota T.

Science. 2019 Jan 25;363(6425):356. doi: 10.1126/science.aaw2342. No abstract available.


Compromised Antibacterial Function of Multipotent Stromal Cells in Diabetes.

Cho Y, Mitchell R, Paudel S, Feltham T, Schon L, Zhang Z.

Stem Cells Dev. 2019 Feb 15;28(4):268-277. doi: 10.1089/scd.2018.0219. Epub 2019 Jan 22.


Results from Nepal's 2018 Report Card on Physical Activity for Children and Youth.

Subedi N, Paudel S, Nepal S, Karki A, Magar M, Mehata S.

J Phys Act Health. 2018 Nov 1;15(S2):S386-S387. doi: 10.1123/jpah.2018-0512. No abstract available.


The genetic insulator RiboJ increases expression of insulated genes.

Clifton KP, Jones EM, Paudel S, Marken JP, Monette CE, Halleran AD, Epp L, Saha MS.

J Biol Eng. 2018 Oct 29;12:23. doi: 10.1186/s13036-018-0115-6. eCollection 2018.


Calcium Signaling in Vertebrate Development and Its Role in Disease.

Paudel S, Sindelar R, Saha M.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3390. doi: 10.3390/ijms19113390. Review.


Physical activity participation and the risk of chronic diseases among South Asian adults: protocol for a systematic review and meta-analysis.

Paudel S, Owen AJ, Owusu-Addo E, Smith BJ.

Syst Rev. 2018 Oct 30;7(1):177. doi: 10.1186/s13643-018-0848-9.


Lingual cavernous hemangioma in a Nepalese boy-'A Difficult Associate!!!'

Shrestha AL, Paudel SB.

J Surg Case Rep. 2018 Oct 23;2018(10):rjy283. doi: 10.1093/jscr/rjy283. eCollection 2018 Oct.


Identical Genetic Profiles of Escherichia coli Isolates from the Gut and Systemic Organs of Chickens Indicate Systemic Bacterial Dissemination, Most Likely Due to Intestinal Destruction Caused by Histomonosis.

Paudel S, Stessl B, Fürst C, Jandreski-Cvetkovic D, Hess M, Hess C.

Avian Dis. 2018 Sep;62(3):300-306. doi: 10.1637/11816-021818-Reg.1.


Expression of trpv channels during Xenopus laevis embryogenesis.

Dong C, Paudel S, Amoh NY, Saha MS.

Gene Expr Patterns. 2018 Dec;30:64-70. doi: 10.1016/j.gep.2018.10.001. Epub 2018 Oct 13.


Design, synthesis, and systematic evaluation of 4-arylpiperazine- and 4-benzylpiperidine napthyl ethers as inhibitors of monoamine neurotransmitters reuptake.

Paudel S, Min X, Acharya S, Khadka DB, Yoon G, Kim KM, Cheon SH.

Bioorg Med Chem. 2018 Nov 1;26(20):5538-5546. doi: 10.1016/j.bmc.2018.09.033. Epub 2018 Sep 26.


NLRC4 suppresses IL-17A-mediated neutrophil-dependent host defense through upregulation of IL-18 and induction of necroptosis during Gram-positive pneumonia.

Paudel S, Ghimire L, Jin L, Baral P, Cai S, Jeyaseelan S.

Mucosal Immunol. 2019 Jan;12(1):247-257. doi: 10.1038/s41385-018-0088-2. Epub 2018 Oct 2.


NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function.

Ghimire L, Paudel S, Jin L, Baral P, Cai S, Jeyaseelan S.

PLoS Pathog. 2018 Sep 24;14(9):e1007308. doi: 10.1371/journal.ppat.1007308. eCollection 2018 Sep.


Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol.

Cho PJ, Paudel S, Lee D, Jin YJ, Jo G, Jeong TC, Lee S, Lee T.

Pharmaceutics. 2018 Aug 30;10(3). pii: E141. doi: 10.3390/pharmaceutics10030141.


Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation.

Shrestha R, Cho PJ, Paudel S, Shrestha A, Kang MJ, Jeong TC, Lee ES, Lee S.

Pharmaceutics. 2018 Aug 2;10(3). pii: E112. doi: 10.3390/pharmaceutics10030112.


Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency.

Reagan AM, Gu X, Paudel S, Ashpole NM, Zalles M, Sonntag WE, Ungvari Z, Csiszar A, Otalora L, Freeman WM, Stout MB, Elliott MH.

Neurobiol Aging. 2018 Nov;71:1-12. doi: 10.1016/j.neurobiolaging.2018.06.039. Epub 2018 Jul 10.


Design, synthesis and docking study of 4-arylpiperazine carboxamides as monoamine neurotransmitters reuptake inhibitors.

Paudel S, Sun N, Khadka DB, Yoon G, Kim KM, Cheon SH.

Bioorg Med Chem. 2018 Aug 7;26(14):4127-4135. doi: 10.1016/j.bmc.2018.06.043. Epub 2018 Jul 2.


Deriving Economic Models for Pea Aphid (Hemiptera: Aphididae) as a Direct-Pest and a Virus-Vector on Commercial Lentils.

Paudel S, Bechinski EJ, Stokes BS, Pappu HR, Eigenbrode SD.

J Econ Entomol. 2018 Sep 26;111(5):2225-2232. doi: 10.1093/jee/toy188.


A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells.

Fujioka Y, Nishide S, Ose T, Suzuki T, Kato I, Fukuhara H, Fujioka M, Horiuchi K, Satoh AO, Nepal P, Kashiwagi S, Wang J, Horiguchi M, Sato Y, Paudel S, Nanbo A, Miyazaki T, Hasegawa H, Maenaka K, Ohba Y.

Cell Host Microbe. 2018 Jun 13;23(6):809-818.e5. doi: 10.1016/j.chom.2018.04.015. Epub 2018 May 17.


Epidemiological Characteristics of Dorsal and Lumbar Spine Trauma Presenting to a Trauma Hospital in Kathmandu, Nepal: Formulation of a National Spine Policy.

Dhakal GR, Paudel S, Dhungana S, Gurung G, Kawaguchi Y.

Spine Surg Relat Res. 2018 Apr 27;2(4):249-252. doi: 10.22603/ssrr.2017-0087. eCollection 2018 Oct 26.


The human clone ST22 SCCmec IV methicillin-resistant Staphylococcus aureus isolated from swine herds and wild primates in Nepal: is man the common source?

Roberts MC, Joshi PR, Greninger AL, Melendez D, Paudel S, Acharya M, Bimali NK, Koju NP, No D, Chalise M, Kyes RC.

FEMS Microbiol Ecol. 2018 May 1;94(5). doi: 10.1093/femsec/fiy052.


Orthotopic Transplantation of Achilles Tendon Allograft in Rats: With or without Incorporation of Autologous Mesenchymal Stem Cells.

Aynardi M, Zahoor T, Mitchell R, Loube J, Feltham T, Manandhar L, Paudel S, Schon L, Zhang Z.

Cell Transplant. 2018 Feb;27(2):245-255. doi: 10.1177/0963689717745891.


Escherichia coli isolates from femoral bone marrow of broilers exhibit diverse pheno- and genotypic characteristics that do not correlate with macroscopic lesions of bacterial chondronecrosis with osteomyelitis.

Gaußmann B, Hess C, Grafl B, Kovacs M, Troxler S, Stessl B, Hess M, Paudel S.

Avian Pathol. 2018 Jun;47(3):271-280. doi: 10.1080/03079457.2018.1440065. Epub 2018 Mar 14.


Genome Sequences of Mycobacteriophages Amgine, Amohnition, Bella96, Cain, DarthP, Hammy, Krueger, LastHope, Peanam, PhelpsODU, Phrank, SirPhilip, Slimphazie, and Unicorn.

Anders KR, Barekzi N, Best AA, Frederick GD, Mavrodi DV, Vazquez E; SEA-PHAGES, Amoh NYA, Baliraine FN, Buchser WJ, Cast TP, Chamberlain CE, Chung HM, D'Angelo WA, Farris CT, Fernandez-Martinez M, Fischman HD, Forsyth MH, Fortier AG, Gallo KF, Held GJ, Lomas MA, Maldonado-Vazquez NY, Moonsammy CH, Namboote P, Paudel S, Polley SM, Reyes GM, Rubin MR, Saha MS, Stukey J, Tobias TD, Garlena RA, Stoner TH, Cresawn SG, Jacobs-Sera D, Pope WH, Russell DA, Hatfull GF.

Genome Announc. 2017 Dec 7;5(49). pii: e01202-17. doi: 10.1128/genomeA.01202-17.


Genome Sequences of 19 Rhodococcus erythropolis Cluster CA Phages.

Bonilla JA, Isern S, Findley AM, Klyczek KK, Michael SF, Saha MS, Buchser WJ, Forsyth MH, Paudel S, Gissendanner CR, Wiedemeier AMD, Alonzo FL; University of Wisconsin–River Falls SEA-PHAGES; Florida Gulf Coast University SEA-PHAGES; University of Louisiana–Monroe SEA-PHAGES; College of William & Mary SEA-PHAGES, Garlena RA, Russell DA, Pope WH, Cresawn SG, Jacobs-Sera D, Hatfull GF.

Genome Announc. 2017 Dec 7;5(49). pii: e01201-17. doi: 10.1128/genomeA.01201-17.


Statistical analysis of co-occurrence patterns in microbial presence-absence datasets.

Mainali KP, Bewick S, Thielen P, Mehoke T, Breitwieser FP, Paudel S, Adhikari A, Wolfe J, Slud EV, Karig D, Fagan WF.

PLoS One. 2017 Nov 16;12(11):e0187132. doi: 10.1371/journal.pone.0187132. eCollection 2017.


Effect of Low-Intensity Pulsed Ultrasound on Joint Injury and Post-Traumatic Osteoarthritis: an Animal Study.

Zahoor T, Mitchell R, Bhasin P, Guo Y, Paudel S, Schon L, Zhang Z.

Ultrasound Med Biol. 2018 Jan;44(1):234-242. doi: 10.1016/j.ultrasmedbio.2017.09.014. Epub 2017 Oct 27.


Correlates of mobile screen media use among children aged 0-8: a systematic review.

Paudel S, Jancey J, Subedi N, Leavy J.

BMJ Open. 2017 Oct 24;7(10):e014585. doi: 10.1136/bmjopen-2016-014585. Review.


Presence of Avibacterium paragallinarum and Histopathologic Lesions Corresponds with Clinical Signs in a Co-infection Model with Gallibacterium anatis.

Paudel S, Ruhnau D, Wernsdorf P, Liebhart D, Hess M, Hess C.

Avian Dis. 2017 Sep;61(3):335-340. doi: 10.1637/11609-021317-RegR.


Factors determining satisfaction among facility-based maternity clients in Nepal.

Mehata S, Paudel YR, Dariang M, Aryal KK, Paudel S, Mehta R, King S, Barnett S.

BMC Pregnancy Childbirth. 2017 Sep 25;17(1):319. doi: 10.1186/s12884-017-1532-0.


Emerging Roles of Inflammasomes in Acute Pneumonia.

Ravi Kumar S, Paudel S, Ghimire L, Bergeron S, Cai S, Zemans RL, Downey GP, Jeyaseelan S.

Am J Respir Crit Care Med. 2018 Jan 15;197(2):160-171. doi: 10.1164/rccm.201707-1391PP. Review. No abstract available.


Pretreatment of agricultural biomass for anaerobic digestion: Current state and challenges.

Paudel SR, Banjara SP, Choi OK, Park KY, Kim YM, Lee JW.

Bioresour Technol. 2017 Dec;245(Pt A):1194-1205. doi: 10.1016/j.biortech.2017.08.182. Epub 2017 Sep 1. Review.


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