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Items: 7

1.

Dynamics of drug response informs rational combination regimens.

Paudel BB, Quaranta V.

Sci Signal. 2019 Aug 20;12(595). pii: eaax9742. doi: 10.1126/scisignal.aax9742. Review.

PMID:
31431544
2.

Quantifying Drug Combination Synergy along Potency and Efficacy Axes.

Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V.

Cell Syst. 2019 Feb 27;8(2):97-108.e16. doi: 10.1016/j.cels.2019.01.003. Epub 2019 Feb 20.

PMID:
30797775
3.

Metabolic plasticity meets gene regulation.

Paudel BB, Quaranta V.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3370-3372. doi: 10.1073/pnas.1900169116. Epub 2019 Feb 8. No abstract available.

4.

A Nonquiescent "Idling" Population State in Drug-Treated, BRAF-Mutated Melanoma.

Paudel BB, Harris LA, Hardeman KN, Abugable AA, Hayford CE, Tyson DR, Quaranta V.

Biophys J. 2018 Mar 27;114(6):1499-1511. doi: 10.1016/j.bpj.2018.01.016.

5.

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition.

Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP.

Sci Rep. 2017 Feb 16;7:42604. doi: 10.1038/srep42604.

6.

An unbiased metric of antiproliferative drug effect in vitro.

Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR.

Nat Methods. 2016 Jun;13(6):497-500. doi: 10.1038/nmeth.3852. Epub 2016 May 2.

7.

Quantifying heterogeneity and dynamics of clonal fitness in response to perturbation.

Frick PL, Paudel BB, Tyson DR, Quaranta V.

J Cell Physiol. 2015 Jul;230(7):1403-12. doi: 10.1002/jcp.24888.

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