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Items: 1 to 50 of 112

1.

Modulation of Caspase-3 activity using a redox active vitamin K3 analogue, plumbagin, as a novel strategy for radioprotection.

Checker R, Pal D, Patwardhan RS, Basu B, Sharma D, Sandur SK.

Free Radic Biol Med. 2019 Sep 4;143:560-572. doi: 10.1016/j.freeradbiomed.2019.09.001. [Epub ahead of print]

PMID:
31493505
2.

Purification and Characterization of an Active Principle, Lawsone, Responsible for the Plasmid Curing Activity of Plumbago zeylanica Root Extracts.

Patwardhan RB, Dhakephalkar PK, Chopade BA, Dhavale DD, Bhonde RR.

Front Microbiol. 2018 Nov 8;9:2618. doi: 10.3389/fmicb.2018.02618. eCollection 2018.

3.

Diabetic ketoacidosis incidence in children at first presentation of type 1 diabetes at an Australian regional hospital: The effect of health professional education.

Patwardhan R, Gorton S, Vangaveti VN, Yates J.

Pediatr Diabetes. 2018 Aug;19(5):993-999. doi: 10.1111/pedi.12666. Epub 2018 Mar 24.

PMID:
29484782
4.

Cold atmospheric plasma-modulated phorbol 12-myristate 13-acetate-induced differentiation of U937 cells to macrophage-like cells.

Maikho T, Patwardhan RS, Das TN, Sharma D, Sandur SK.

Free Radic Res. 2018 Feb;52(2):212-222. doi: 10.1080/10715762.2017.1423069. Epub 2018 Jan 18.

PMID:
29291631
5.

Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity.

Jayakumar S, Patwardhan RS, Pal D, Singh B, Sharma D, Kutala VK, Sandur SK.

Free Radic Biol Med. 2017 Dec;113:530-538. doi: 10.1016/j.freeradbiomed.2017.10.378. Epub 2017 Nov 5.

PMID:
29080841
6.

An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns.

Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, Schulze N, Jungkurth JK, Patwardhan R, Solouk D, Hampe N, Hoffmann B, Dehmelt L, Nalbant P.

J Cell Biol. 2017 Dec 4;216(12):4271-4285. doi: 10.1083/jcb.201706052. Epub 2017 Oct 20.

7.

Baicalein induces cell death in murine T cell lymphoma via inhibition of thioredoxin system.

Patwardhan RS, Pal D, Checker R, Sharma D, Sandur SK.

Int J Biochem Cell Biol. 2017 Oct;91(Pt A):45-52. doi: 10.1016/j.biocel.2017.08.015. Epub 2017 Aug 31.

PMID:
28864268
8.

Dimethoxycurcumin, a metabolically stable analogue of curcumin enhances the radiosensitivity of cancer cells: Possible involvement of ROS and thioredoxin reductase.

Jayakumar S, Patwardhan RS, Pal D, Sharma D, Sandur SK.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):446-454. doi: 10.1016/j.bbrc.2016.06.144. Epub 2016 Jul 2.

PMID:
27381867
9.

Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation.

Patwardhan RS, Sharma D, Thoh M, Checker R, Sandur SK.

Biochem Pharmacol. 2016 May 15;108:75-89. doi: 10.1016/j.bcp.2016.03.013. Epub 2016 Mar 23.

PMID:
27019135
10.

Learning the sequence determinants of alternative splicing from millions of random sequences.

Rosenberg AB, Patwardhan RP, Shendure J, Seelig G.

Cell. 2015 Oct 22;163(3):698-711. doi: 10.1016/j.cell.2015.09.054. Epub 2015 Oct 22.

11.

Spatio-temporal changes in glutathione and thioredoxin redox couples during ionizing radiation-induced oxidative stress regulate tumor radio-resistance.

Patwardhan RS, Sharma D, Checker R, Thoh M, Sandur SK.

Free Radic Res. 2015 Oct;49(10):1218-32. doi: 10.3109/10715762.2015.1056180.

PMID:
26021764
12.

Utility of liquid-based cytologic examination of distal esophageal brushings in the management of Barrett esophagus: a prospective study of 45 cases.

Walavalkar V, Patwardhan RV, Owens CL, Lithgow M, Wang X, Akalin A, Nompleggi DJ, Zivny J, Wassef W, Marshall C, Levey J, Walter O, Fischer AH.

J Am Soc Cytopathol. 2015 May - Jun;4(3):113-121. doi: 10.1016/j.jasc.2014.09.208. Epub 2014 Oct 2.

PMID:
31051691
13.

Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.

Birnbaum RY, Patwardhan RP, Kim MJ, Findlay GM, Martin B, Zhao J, Bell RJ, Smith RP, Ku AA, Shendure J, Ahituv N.

PLoS Genet. 2014 Oct 23;10(10):e1004592. doi: 10.1371/journal.pgen.1004592. eCollection 2014 Oct.

14.

Robot-assisted stereotactic laser ablation in medically intractable epilepsy: operative technique.

Gonzalez-Martinez J, Vadera S, Mullin J, Enatsu R, Alexopoulos AV, Patwardhan R, Bingaman W, Najm I.

Neurosurgery. 2014 Jun;10 Suppl 2:167-72; discussion 172-3. doi: 10.1227/NEU.0000000000000286.

PMID:
24448180
15.

1,4-Naphthoquinone, a pro-oxidant, suppresses immune responses via KEAP-1 glutathionylation.

Gambhir L, Checker R, Thoh M, Patwardhan RS, Sharma D, Kumar M, Sandur SK.

Biochem Pharmacol. 2014 Mar 1;88(1):95-105. doi: 10.1016/j.bcp.2013.12.022. Epub 2014 Jan 6.

PMID:
24406247
16.

Mitigation of radiation-induced hematopoietic injury via regulation of cellular MAPK/phosphatase levels and increasing hematopoietic stem cells.

Patwardhan RS, Sharma D, Checker R, Sandur SK.

Free Radic Biol Med. 2014 Mar;68:52-64. doi: 10.1016/j.freeradbiomed.2013.11.004. Epub 2013 Nov 25.

PMID:
24287141
17.

Plumbagin, a vitamin K3 analogue, abrogates lipopolysaccharide-induced oxidative stress, inflammation and endotoxic shock via NF-κB suppression.

Checker R, Patwardhan RS, Sharma D, Menon J, Thoh M, Sandur SK, Sainis KB, Poduval TB.

Inflammation. 2014 Apr;37(2):542-54. doi: 10.1007/s10753-013-9768-y.

PMID:
24234154
18.

Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions.

Burton JN, Adey A, Patwardhan RP, Qiu R, Kitzman JO, Shendure J.

Nat Biotechnol. 2013 Dec;31(12):1119-25. doi: 10.1038/nbt.2727. Epub 2013 Nov 3.

19.

Eltrombopag increases platelet numbers in thrombocytopenic patients with HCV infection and cirrhosis, allowing for effective antiviral therapy.

Afdhal NH, Dusheiko GM, Giannini EG, Chen PJ, Han KH, Mohsin A, Rodriguez-Torres M, Rugina S, Bakulin I, Lawitz E, Shiffman ML, Tayyab GU, Poordad F, Kamel YM, Brainsky A, Geib J, Vasey SY, Patwardhan R, Campbell FM, Theodore D.

Gastroenterology. 2014 Feb;146(2):442-52.e1. doi: 10.1053/j.gastro.2013.10.012. Epub 2013 Oct 12.

PMID:
24126097
20.

Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model.

Smith RP, Taher L, Patwardhan RP, Kim MJ, Inoue F, Shendure J, Ovcharenko I, Ahituv N.

Nat Genet. 2013 Sep;45(9):1021-1028. doi: 10.1038/ng.2713. Epub 2013 Jul 28.

21.

Involvement of ERK-Nrf-2 signaling in ionizing radiation induced cell death in normal and tumor cells.

Patwardhan RS, Checker R, Sharma D, Sandur SK, Sainis KB.

PLoS One. 2013 Jun 11;8(6):e65929. doi: 10.1371/journal.pone.0065929. Print 2013.

22.

Results of a phase I dose escalation study of eltrombopag in patients with advanced soft tissue sarcoma receiving doxorubicin and ifosfamide.

Chawla SP, Staddon A, Hendifar A, Messam CA, Patwardhan R, Kamel YM.

BMC Cancer. 2013 Mar 16;13:121. doi: 10.1186/1471-2407-13-121.

23.

Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB.

Checker R, Patwardhan RS, Sharma D, Menon J, Thoh M, Bhilwade HN, Konishi T, Sandur SK.

Free Radic Biol Med. 2012 Oct 1;53(7):1421-30. doi: 10.1016/j.freeradbiomed.2012.08.006. Epub 2012 Aug 11.

PMID:
22917978
24.

Massively parallel functional dissection of mammalian enhancers in vivo.

Patwardhan RP, Hiatt JB, Witten DM, Kim MJ, Smith RP, May D, Lee C, Andrie JM, Lee SI, Cooper GM, Ahituv N, Pennacchio LA, Shendure J.

Nat Biotechnol. 2012 Feb 26;30(3):265-70. doi: 10.1038/nbt.2136.

25.

Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT.

Checker R, Sandur SK, Sharma D, Patwardhan RS, Jayakumar S, Kohli V, Sethi G, Aggarwal BB, Sainis KB.

PLoS One. 2012;7(2):e31318. doi: 10.1371/journal.pone.0031318. Epub 2012 Feb 20.

26.

γ-Tocotrienol induces apoptosis in human T cell lymphoma through activation of both intrinsic and extrinsic pathways.

Wilankar C, Khan NM, Checker R, Sharma D, Patwardhan R, Gota V, Sandur SK, Devasagayam TP.

Curr Pharm Des. 2011;17(21):2176-89.

PMID:
21774779
27.

Dimethoxycurcumin, a metabolically stable analogue of curcumin, exhibits anti-inflammatory activities in murine and human lymphocytes.

Patwardhan RS, Checker R, Sharma D, Kohli V, Priyadarsini KI, Sandur SK.

Biochem Pharmacol. 2011 Sep 15;82(6):642-57. doi: 10.1016/j.bcp.2011.06.024. Epub 2011 Jun 24.

PMID:
21726543
28.

Vitamin K3 suppressed inflammatory and immune responses in a redox-dependent manner.

Checker R, Sharma D, Sandur SK, Khan NM, Patwardhan RS, Kohli V, Sainis KB.

Free Radic Res. 2011 Aug;45(8):975-85. doi: 10.3109/10715762.2011.585647. Epub 2011 Jun 9.

PMID:
21651451
29.

Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols.

Wilankar C, Sharma D, Checker R, Khan NM, Patwardhan R, Patil A, Sandur SK, Devasagayam TP.

Free Radic Biol Med. 2011 Jul 1;51(1):129-43. doi: 10.1016/j.freeradbiomed.2011.03.038. Epub 2011 Apr 8.

PMID:
21536125
30.

The ecoresponsive genome of Daphnia pulex.

Colbourne JK, Pfrender ME, Gilbert D, Thomas WK, Tucker A, Oakley TH, Tokishita S, Aerts A, Arnold GJ, Basu MK, Bauer DJ, Cáceres CE, Carmel L, Casola C, Choi JH, Detter JC, Dong Q, Dusheyko S, Eads BD, Fröhlich T, Geiler-Samerotte KA, Gerlach D, Hatcher P, Jogdeo S, Krijgsveld J, Kriventseva EV, Kültz D, Laforsch C, Lindquist E, Lopez J, Manak JR, Muller J, Pangilinan J, Patwardhan RP, Pitluck S, Pritham EJ, Rechtsteiner A, Rho M, Rogozin IB, Sakarya O, Salamov A, Schaack S, Shapiro H, Shiga Y, Skalitzky C, Smith Z, Souvorov A, Sung W, Tang Z, Tsuchiya D, Tu H, Vos H, Wang M, Wolf YI, Yamagata H, Yamada T, Ye Y, Shaw JR, Andrews J, Crease TJ, Tang H, Lucas SM, Robertson HM, Bork P, Koonin EV, Zdobnov EM, Grigoriev IV, Lynch M, Boore JL.

Science. 2011 Feb 4;331(6017):555-61. doi: 10.1126/science.1197761.

31.

Haplotype-resolved genome sequencing of a Gujarati Indian individual.

Kitzman JO, Mackenzie AP, Adey A, Hiatt JB, Patwardhan RP, Sudmant PH, Ng SB, Alkan C, Qiu R, Eichler EE, Shendure J.

Nat Biotechnol. 2011 Jan;29(1):59-63. doi: 10.1038/nbt.1740. Epub 2010 Dec 19. Erratum in: Nat Biotechnol. 2011 May;29(5):459.

32.

A randomized, double-blind, placebo-controlled, dose ranging study to assess the efficacy and safety of eltrombopag in patients receiving carboplatin/paclitaxel for advanced solid tumors.

Kellum A, Jagiello-Gruszfeld A, Bondarenko IN, Patwardhan R, Messam C, Mostafa Kamel Y.

Curr Med Res Opin. 2010 Oct;26(10):2339-46. doi: 10.1185/03007995.2010.510051.

PMID:
20735290
33.

Parallel, tag-directed assembly of locally derived short sequence reads.

Hiatt JB, Patwardhan RP, Turner EH, Lee C, Shendure J.

Nat Methods. 2010 Feb;7(2):119-22. doi: 10.1038/nmeth.1416. Epub 2010 Jan 17.

34.

High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis.

Patwardhan RP, Lee C, Litvin O, Young DL, Pe'er D, Shendure J.

Nat Biotechnol. 2009 Dec;27(12):1173-5. doi: 10.1038/nbt.1589.

35.

Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function.

Costello JC, Dalkilic MM, Beason SM, Gehlhausen JR, Patwardhan R, Middha S, Eads BD, Andrews JR.

Genome Biol. 2009;10(9):R97. doi: 10.1186/gb-2009-10-9-r97. Epub 2009 Sep 16.

36.

Complications of posterior cranial fossa surgery--an institutional experience of 500 patients.

Dubey A, Sung WS, Shaya M, Patwardhan R, Willis B, Smith D, Nanda A.

Surg Neurol. 2009 Oct;72(4):369-75. doi: 10.1016/j.surneu.2009.04.001. Epub 2009 Jul 14.

PMID:
19604553
37.

A study on nosocomial pathogens in ICU with special reference to multiresistant Acinetobacter baumannii harbouring multiple plasmids.

Patwardhan RB, Dhakephalkar PK, Niphadkar KB, Chopade BA.

Indian J Med Res. 2008 Aug;128(2):178-87.

PMID:
19001682
38.

Curing plasmid-mediated vancomycin resistance in Staphylococcus aureus using herbal naphthoquinones.

Jahagirdar S, Patwardhan R, Dhakephalkar PK.

J Hosp Infect. 2008 Nov;70(3):289-91. doi: 10.1016/j.jhin.2006.04.021. No abstract available.

PMID:
18799244
39.

Trigeminal neuralgia: a modern-day review.

Hunt K, Patwardhan R.

Int Rev Neurobiol. 2007;79:621-31. Review.

PMID:
17531861
40.

Left vagus nerve stimulation for depression: first implantation case post-fDA approval and review of the literature.

Patwardhan R, Cardenas R, Myers D, Ware P, Nanda A.

J La State Med Soc. 2007 Jan-Feb;159(1):38-41. Review.

PMID:
17396474
41.

Computer simulation and tank experimental verification of concentric ring electrodes.

Koka K, Patwardhan R, Besio W.

Conf Proc IEEE Eng Med Biol Soc. 2004;3:2243-6.

PMID:
17272173
42.

The voice-controlled robotic assist scope holder AESOP for the endoscopic approach to the sella.

Nathan CO, Chakradeo V, Malhotra K, D'Agostino H, Patwardhan R.

Skull Base. 2006 Aug;16(3):123-31.

43.

A one-year study comparing the efficacy and safety of rosiglitazone and glibenclamide in the treatment of type 2 diabetes.

Hanefeld M, Patwardhan R, Jones NP; Rosiglitazone Clinical Trials Study Group.

Nutr Metab Cardiovasc Dis. 2007 Jan;17(1):13-23. Epub 2006 Mar 20.

PMID:
17174222
44.

Endoscopic management of metastatic synovial sarcoma to the pancreas.

Patel S, Martins N, Yantis R, Shepro D, Levey J, Patwardhan R.

Pancreas. 2006 Aug;33(2):205-6. No abstract available.

PMID:
16868493
45.

Neurosurgical treatment of multiple sclerosis.

Patwardhan RV, Minagar A, Kelley RE, Nanda A.

Neurol Res. 2006 Apr;28(3):320-5. Review.

PMID:
16687060
46.

Intraspinal synovial cysts: a retrospective study.

Acharya R, Patwardhan RV, Smith DR, Willis BK, Fowler M, Nanda A.

Neurol India. 2006 Mar;54(1):38-41.

47.

Idiopathic primary pan intra-ventricular hemorrhage in a child.

Patwardhan RV, Fowler M, Willis BK, Nanda A.

Neurol India. 2005 Sep;53(3):373-4. No abstract available.

48.

Cyclooxygenase-2 expression in brain metastases.

Karim A, Fowler M, Jones L, Patwardhan R, Vannemreddy P, Mccarthy K, Nanda A.

Anticancer Res. 2005 Jul-Aug;25(4):2969-71.

49.

Control of refractory status epilepticus precipitated by anticonvulsant withdrawal using left vagal nerve stimulation: a case report.

Patwardhan RV, Dellabadia J Jr, Rashidi M, Grier L, Nanda A.

Surg Neurol. 2005 Aug;64(2):170-3.

PMID:
16051017
50.

Electroconvulsive therapy for seizure control: preliminary data in a new seizure generation and control model.

Patwardhan RV, Besio W, Calvert JW, Kusaka G, Kusaka I, Zhang J, Nanda A.

Front Biosci. 2005 Sep 1;10:3013-9.

PMID:
15970556

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