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Items: 1 to 50 of 64

1.

Good Things in Small Packages: an Innovative Delivery Approach for Inhaled Insulin.

Fink JB, Molloy L, Patton JS, Galindo-Filho VC, de Melo Barcelar J, Alcoforado L, Brandão SCS, de Andrade AD.

Pharm Res. 2017 Dec;34(12):2568-2578. doi: 10.1007/s11095-017-2215-2. Epub 2017 Jul 17.

PMID:
28718049
2.

Response to paper by Singh et al. "Hyperinsulinemia adversely affects lung structure and function".

Wolff RK, Brain JD, Patton JS, Liggitt D.

Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L180-2. doi: 10.1152/ajplung.00187.2016. No abstract available.

3.

Discovery of an L-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100.

Kim SH, Tangallapally R, Kim IC, Trovato R, Parker D, Patton JS, Reeves L, Bradford C, Wettstein D, Baichwal V, Papac D, Bajji A, Carlson R, Yager KM.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5254-7. doi: 10.1016/j.bmcl.2015.09.053. Epub 2015 Sep 28.

PMID:
26483201
4.

Reverse transcription polymerase chain reaction (RT-PCR) analysis of proteolytic enzymes in cultures of human respiratory epithelial cells.

Baginski L, Tachon G, Falson F, Patton JS, Bakowsky U, Ehrhardt C.

J Aerosol Med Pulm Drug Deliv. 2011 Apr;24(2):89-101. doi: 10.1089/jamp.2010.0842. Epub 2011 Mar 16.

PMID:
21410325
5.

The particle has landed--characterizing the fate of inhaled pharmaceuticals.

Patton JS, Brain JD, Davies LA, Fiegel J, Gumbleton M, Kim KJ, Sakagami M, Vanbever R, Ehrhardt C.

J Aerosol Med Pulm Drug Deliv. 2010 Dec;23 Suppl 2:S71-87. doi: 10.1089/jamp.2010.0836. Review.

PMID:
21133802
6.

Interview with John Patton.

Patton JS.

Ther Deliv. 2010 Sep;1(3):375-81. No abstract available.

PMID:
22816140
7.

Inhaling medicines: delivering drugs to the body through the lungs.

Patton JS, Byron PR.

Nat Rev Drug Discov. 2007 Jan;6(1):67-74. Review.

PMID:
17195033
8.

A recombinant human enzyme for enhanced interstitial transport of therapeutics.

Bookbinder LH, Hofer A, Haller MF, Zepeda ML, Keller GA, Lim JE, Edgington TS, Shepard HM, Patton JS, Frost GI.

J Control Release. 2006 Aug 28;114(2):230-41. Epub 2006 Jun 7.

PMID:
16876899
9.

A historical perspective on convergence technology.

Patton JS.

Nat Biotechnol. 2006 Mar;24(3):280-1. No abstract available.

PMID:
16525388
10.

Unlocking the opportunity of tight glycaemic control. Innovative delivery of insulin via the lung.

Patton JS.

Diabetes Obes Metab. 2005 Nov;7 Suppl 1:S5-8. Review.

PMID:
16135136
11.

The lungs as a portal of entry for systemic drug delivery.

Patton JS, Fishburn CS, Weers JG.

Proc Am Thorac Soc. 2004;1(4):338-44. Review.

PMID:
16113455
12.

Clinical pharmacokinetics and pharmacodynamics of inhaled insulin.

Patton JS, Bukar JG, Eldon MA.

Clin Pharmacokinet. 2004;43(12):781-801. Review.

PMID:
15355125
13.

Pulmonary delivery of drugs for bone disorders.

Patton JS.

Adv Drug Deliv Rev. 2000 Aug 31;42(3):239-48. Review.

PMID:
10963838
14.

Inhaled insulin.

Patton JS, Bukar J, Nagarajan S.

Adv Drug Deliv Rev. 1999 Feb 1;35(2-3):235-247.

PMID:
10837699
15.

Inhalation delivery of therapeutic peptides and proteins.

Patton JS.

J Aerosol Med. 1999 Summer;12(2):45-6. doi: 10.1089/jam.1999.12.45. No abstract available.

PMID:
19298114
16.

Polycomb group repression is blocked by the Drosophila suppressor of Hairy-wing [su(Hw)] insulator.

Mallin DR, Myung JS, Patton JS, Geyer PK.

Genetics. 1998 Jan;148(1):331-9.

17.

In situ and in vivo methods for pulmonary delivery.

Eljamal M, Nagarajan S, Patton JS.

Pharm Biotechnol. 1996;8:361-74. Review. No abstract available.

PMID:
8791819
18.

Developmental analysis of the ovarian tumor gene during Drosophila oogenesis.

Rodesch C, Geyer PK, Patton JS, Bae E, Nagoshi RN.

Genetics. 1995 Sep;141(1):191-202.

19.
20.

Drug delivery via the respiratory tract.

Byron PR, Patton JS.

J Aerosol Med. 1994;7(1):49-75.

PMID:
10147058
22.

Position-independent germline transformation in Drosophila using a cuticle pigmentation gene as a selectable marker.

Patton JS, Gomes XV, Geyer PK.

Nucleic Acids Res. 1992 Nov 11;20(21):5859-60. No abstract available.

23.

The pattern of lung injury induced after pulmonary exposure to tumor necrosis factor-alpha depends on the route of administration.

Fuchs HJ, Debs R, Patton JS, Liggitt HD.

Diagn Microbiol Infect Dis. 1990 Sep-Oct;13(5):397-404.

PMID:
2149315
24.

Inhibition of lipolysis by hydrocarbons and fatty alcohols.

Ferreira GC, Patton JS.

J Lipid Res. 1990 May;31(5):889-97.

25.

Recombinant tumor necrosis factor-alpha chronically administered in rats: lack of cachectic effect.

Mullen BJ, Harris RB, Patton JS, Martin RJ.

Proc Soc Exp Biol Med. 1990 Apr;193(4):318-25.

PMID:
2320602
26.

Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs.

Kohrogi H, Nadel JA, Malfroy B, Gorman C, Bridenbaugh R, Patton JS, Borson DB.

J Clin Invest. 1989 Sep;84(3):781-6.

27.

Early metabolic response to tumor necrosis factor in mouse sarcoma: a phosphorus-31 nuclear magnetic resonance study.

Shine N, Palladino MA Jr, Patton JS, Deisseroth A, Karczmar GS, Matson GB, Weiner MW.

Cancer Res. 1989 Apr 15;49(8):2123-7.

28.

Human immunodeficiency virus-infected T cells and monocytes are killed by monoclonal human anti-gp41 antibodies coupled to ricin A chain.

Till MA, Zolla-Pazner S, Gorny MK, Patton JS, Uhr JW, Vitetta ES.

Proc Natl Acad Sci U S A. 1989 Mar;86(6):1987-91.

29.

Growth hormone treatment reduces total body fat accumulation in Zucker obese rats.

Martin RJ, Drewry M, Jewell D, Harris RB, Young R, Patton JS.

Int J Obes. 1989;13(3):327-35.

PMID:
2767884
30.

Absorption of human growth hormone from the rat lung.

Patton JS, McCabe JG, Hansen SE, Daugherty AL.

Biotechnol Ther. 1989-1990;1(3):213-28.

PMID:
2562650
31.

Induction of monooxygenase activity in the intestine of spot (Leiostomus xanthurus), a marine teleost, by dietary polycyclic aromatic hydrocarbons.

van Veld PA, Stegeman JJ, Woodin BR, Patton JS, Lee RF.

Drug Metab Dispos. 1988 Sep-Oct;16(5):659-65.

PMID:
2906586
32.

Lung-specific delivery of cytokines induces sustained pulmonary and systemic immunomodulation in rats.

Debs RJ, Fuchs HJ, Philip R, Montgomery AB, Brunette EN, Liggitt D, Patton JS, Shellito JE.

J Immunol. 1988 May 15;140(10):3482-8.

PMID:
3283235
34.

Effects of cholecystokinin peptides on digestive enzymes in killifish in vivo.

Honkanen RE, Crim JW, Patton JS.

Comp Biochem Physiol A Comp Physiol. 1988;89(4):655-60.

PMID:
2899485
35.

Development of partial tolerance to the gastrointestinal effects of high doses of recombinant tumor necrosis factor-alpha in rodents.

Patton JS, Peters PM, McCabe J, Crase D, Hansen S, Chen AB, Liggitt D.

J Clin Invest. 1987 Dec;80(6):1587-96.

36.

Bile salt absorption in killifish intestine.

Honkanen RE, Patton JS.

Am J Physiol. 1987 Dec;253(6 Pt 1):G730-6.

PMID:
3425714
37.

Dietary fat inhibits the intestinal metabolism of the carcinogen benzo[a]pyrene in fish.

Van Veld PA, Vetter RD, Lee RF, Patton JS.

J Lipid Res. 1987 Jul;28(7):810-7.

38.

Possible relationships between in vivo antitumour activity and toxicity of tumour necrosis factor-alpha.

Palladino MA Jr, Patton JS, Figari IS, Shalaby MR.

Ciba Found Symp. 1987;131:21-38. Review.

PMID:
3330012
39.

Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.

Patton JS, Shepard HM, Wilking H, Lewis G, Aggarwal BB, Eessalu TE, Gavin LA, Grunfeld C.

Proc Natl Acad Sci U S A. 1986 Nov;83(21):8313-7.

40.

Visualization by freeze fracture, in vitro and in vivo, of the products of fat digestion.

Rigler MW, Honkanen RE, Patton JS.

J Lipid Res. 1986 Aug;27(8):836-57.

41.

Tumor necrosis factors: gene structure and biological activities.

Goeddel DV, Aggarwal BB, Gray PW, Leung DW, Nedwin GE, Palladino MA, Patton JS, Pennica D, Shepard HM, Sugarman BJ, et al.

Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:597-609. No abstract available.

PMID:
3472740
42.

Dietary fat assimilation and bile salt absorption in the killifish intestine.

Honkanen RE, Rigler MW, Patton JS.

Am J Physiol. 1985 Sep;249(3 Pt 1):G399-407.

PMID:
4037087
44.

Intramembranous particles are clustered on microvillus membrane vesicles.

Rigler MW, Ferreira GC, Patton JS.

Biochim Biophys Acta. 1985 Jun 11;816(1):131-41.

PMID:
4005232
45.
46.

Similar bioavailability and lymphatic transport of benzo(a)pyrene when administered to rats in different amounts of dietary fat.

Laher JM, Rigler MW, Vetter RD, Barrowman JA, Patton JS.

J Lipid Res. 1984 Dec 1;25(12):1337-42.

47.

A simple inexpensive cryogenic storage device for microscopy specimens.

Rigler MW, Patton JS.

J Microsc. 1984 Jun;134(Pt 3):335-6.

PMID:
6748061
48.

Solubility of fatty acids and other hydrophobic molecules in liquid trioleoylglycerol.

Patton JS, Stone B, Papa C, Abramowitz R, Yalkowsky SH.

J Lipid Res. 1984 Feb;25(2):189-97.

49.

Rapid quantification on Chromarods of cholesterol, total bile salts and phospholipids from the same microliter sample of human gallbladder bile.

Rigler MW, Leffert RL, Patton JS.

J Chromatogr. 1983 Oct 14;277:321-7. No abstract available.

PMID:
6643616
50.

Treatment of fever.

Patton JS.

N Engl J Med. 1983 Oct 13;309(15):925. No abstract available.

PMID:
6888490

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