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Items: 38


Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells.

Xiao AY, Maynard MR, Piett CG, Nagel ZD, Alexander JS, Kevil CG, Berridge MV, Pattillo CB, Rosen LR, Miriyala S, Harrison L.

Redox Biol. 2019 Sep;26:101220. doi: 10.1016/j.redox.2019.101220. Epub 2019 May 16.


Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration.

Abdullah CS, Alam S, Aishwarya R, Miriyala S, Bhuiyan MAN, Panchatcharam M, Pattillo CB, Orr AW, Sadoshima J, Hill JA, Bhuiyan MS.

Sci Rep. 2019 Feb 14;9(1):2002. doi: 10.1038/s41598-018-37862-3.


Hydrogen sulfide: Therapeutic or injurious in ischemic stroke?

Gopalakrishnan P, Shrestha B, Kaskas AM, Green J, Alexander JS, Pattillo CB.

Pathophysiology. 2019 Mar;26(1):1-10. doi: 10.1016/j.pathophys.2018.10.005. Epub 2018 Nov 12. Review.


Effect of diabetes and hyaluronidase on the retinal endothelial glycocalyx in mice.

Leskova W, Pickett H, Eshaq RS, Shrestha B, Pattillo CB, Harris NR.

Exp Eye Res. 2019 Feb;179:125-131. doi: 10.1016/j.exer.2018.11.012. Epub 2018 Nov 13.


Decreases in GSH:GSSG activate vascular endothelial growth factor receptor 2 (VEGFR2) in human aortic endothelial cells.

Prasai PK, Shrestha B, Orr AW, Pattillo CB.

Redox Biol. 2018 Oct;19:22-27. doi: 10.1016/j.redox.2018.07.015. Epub 2018 Jul 25.


Differential arterial and venous endothelial redox responses to oxidative stress.

Shrestha B, Prasai PK, Kaskas AM, Khanna A, Letchuman V, Letchuman S, Alexander JS, Orr AW, Woolard MD, Pattillo CB.

Microcirculation. 2018 Oct;25(7):e12486. doi: 10.1111/micc.12486. Epub 2018 Jul 23.


EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity.

Funk SD, Finney AC, Yurdagul A Jr, Pattillo CB, Orr AW.

Cell Signal. 2018 Sep;49:30-38. doi: 10.1016/j.cellsig.2018.05.008. Epub 2018 May 21.


Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes.

Alam S, Abdullah CS, Aishwarya R, Orr AW, Traylor J, Miriyala S, Panchatcharam M, Pattillo CB, Bhuiyan MS.

Biosci Rep. 2017 Jul 16;37(4). pii: BSR20170898. doi: 10.1042/BSR20170898. Print 2017 Aug 31.


EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.

Finney AC, Funk SD, Green JM, Yurdagul A Jr, Rana MA, Pistorius R, Henry M, Yurochko A, Pattillo CB, Traylor JG, Chen J, Woolard MD, Kevil CG, Orr AW.

Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9.


Integrin signaling in atherosclerosis.

Finney AC, Stokes KY, Pattillo CB, Orr AW.

Cell Mol Life Sci. 2017 Jun;74(12):2263-2282. doi: 10.1007/s00018-017-2490-4. Epub 2017 Feb 28. Review.


Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression.

Yurdagul A Jr, Sulzmaier FJ, Chen XL, Pattillo CB, Schlaepfer DD, Orr AW.

J Cell Sci. 2016 Apr 15;129(8):1580-91. doi: 10.1242/jcs.182097. Epub 2016 Feb 18.


Oxygen tension, H2S, and NO bioavailability: is there an interaction?

Kolluru GK, Prasai PK, Kaskas AM, Letchuman V, Pattillo CB.

J Appl Physiol (1985). 2016 Jan 15;120(2):263-70. doi: 10.1152/japplphysiol.00365.2015. Epub 2015 Sep 17. Review.


A novel hydrogen sulfide prodrug, SG1002, promotes hydrogen sulfide and nitric oxide bioavailability in heart failure patients.

Polhemus DJ, Li Z, Pattillo CB, Gojon G Sr, Gojon G Jr, Giordano T, Krum H.

Cardiovasc Ther. 2015 Aug;33(4):216-26. doi: 10.1111/1755-5922.12128.


Nitrite anion therapy protects against chronic ischemic tissue injury in db/db diabetic mice in a NO/VEGF-dependent manner.

Bir SC, Pattillo CB, Pardue S, Kolluru GK, Shen X, Giordano T, Kevil CG.

Diabetes. 2014 Jan;63(1):270-81. doi: 10.2337/db13-0890. Epub 2013 Sep 5.


Control of angiogenesis dictated by picomolar superoxide levels.

Bir SC, Shen X, Kavanagh TJ, Kevil CG, Pattillo CB.

Free Radic Biol Med. 2013 Oct;63:135-42. doi: 10.1016/j.freeradbiomed.2013.05.015. Epub 2013 May 16.


Hydrogen sulfide stimulates ischemic vascular remodeling through nitric oxide synthase and nitrite reduction activity regulating hypoxia-inducible factor-1α and vascular endothelial growth factor-dependent angiogenesis.

Bir SC, Kolluru GK, McCarthy P, Shen X, Pardue S, Pattillo CB, Kevil CG.

J Am Heart Assoc. 2012 Oct;1(5):e004093. doi: 10.1161/JAHA.112.004093. Epub 2012 Oct 25.


Nitrite anion stimulates ischemic arteriogenesis involving NO metabolism.

Bir SC, Pattillo CB, Pardue S, Kolluru GK, Docherty J, Goyette D, Dvorsky P, Kevil CG.

Am J Physiol Heart Circ Physiol. 2012 Jul 15;303(2):H178-88. doi: 10.1152/ajpheart.01086.2010. Epub 2012 May 18.


VEGF₁₆₄ isoform specific regulation of T-cell-dependent experimental colitis in mice.

Chidlow JH Jr, Glawe JD, Pattillo CB, Pardue S, Zhang S, Kevil CG.

Inflamm Bowel Dis. 2011 Jul;17(7):1501-12. doi: 10.1002/ibd.21525. Epub 2010 Nov 9.


Inorganic nitrite therapy: historical perspective and future directions.

Kevil CG, Kolluru GK, Pattillo CB, Giordano T.

Free Radic Biol Med. 2011 Aug 1;51(3):576-93. doi: 10.1016/j.freeradbiomed.2011.04.042. Epub 2011 May 4. Review.


Measurement of plasma hydrogen sulfide in vivo and in vitro.

Shen X, Pattillo CB, Pardue S, Bir SC, Wang R, Kevil CG.

Free Radic Biol Med. 2011 May 1;50(9):1021-31. doi: 10.1016/j.freeradbiomed.2011.01.025. Epub 2011 Jan 27.


Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress.

Pattillo CB, Bir SC, Branch BG, Greber E, Shen X, Pardue S, Patel RP, Kevil CG.

Free Radic Biol Med. 2011 Jan 15;50(2):262-9. doi: 10.1016/j.freeradbiomed.2010.10.714. Epub 2010 Nov 9.


Reperfusion of chronic tissue ischemia: nitrite and dipyridamole regulation of innate immune responses.

Pattillo CB, Fang K, Terracciano J, Kevil CG.

Ann N Y Acad Sci. 2010 Oct;1207:83-8. doi: 10.1111/j.1749-6632.2010.05737.x. Review.


Temporal genomewide expression profiling of DSS colitis reveals novel inflammatory and angiogenesis genes similar to ulcerative colitis.

Fang K, Bruce M, Pattillo CB, Zhang S, Stone R 2nd, Clifford J, Kevil CG.

Physiol Genomics. 2011 Jan 7;43(1):43-56. doi: 10.1152/physiolgenomics.00138.2010. Epub 2010 Oct 5.


Inorganic nitrite and chronic tissue ischaemia: a novel therapeutic modality for peripheral vascular diseases.

Pattillo CB, Bir S, Rajaram V, Kevil CG.

Cardiovasc Res. 2011 Feb 15;89(3):533-41. doi: 10.1093/cvr/cvq297. Epub 2010 Sep 16. Review.


ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway.

Pattillo CB, Pardue S, Shen X, Fang K, Langston W, Jourd'heuil D, Kavanagh TJ, Patel RP, Kevil CG.

Free Radic Biol Med. 2010 Sep 15;49(6):1119-28. doi: 10.1016/j.freeradbiomed.2010.06.030. Epub 2010 Jul 13.


Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.

Venkatesh PK, Pattillo CB, Branch B, Hood J, Thoma S, Illum S, Pardue S, Teng X, Patel RP, Kevil CG.

Cardiovasc Res. 2010 Mar 1;85(4):661-70. doi: 10.1093/cvr/cvq002. Epub 2010 Jan 8.


Genome expression profiling and network analysis of nitrite therapy during chronic ischemia: possible mechanisms and interesting molecules.

Pattillo CB, Fang K, Pardue S, Kevil CG.

Nitric Oxide. 2010 Feb 15;22(2):168-79. doi: 10.1016/j.niox.2009.11.008. Epub 2009 Dec 4.


Hydrogen sulfide mediates cardioprotection through Nrf2 signaling.

Calvert JW, Jha S, Gundewar S, Elrod JW, Ramachandran A, Pattillo CB, Kevil CG, Lefer DJ.

Circ Res. 2009 Aug 14;105(4):365-74. doi: 10.1161/CIRCRESAHA.109.199919. Epub 2009 Jul 16.


Radiation-guided targeting of combretastatin encapsulated immunoliposomes to mammary tumors.

Pattillo CB, Venegas B, Donelson FJ, Del Valle L, Knight LC, Chong PL, Kiani MF.

Pharm Res. 2009 May;26(5):1093-100. doi: 10.1007/s11095-009-9826-1. Epub 2009 Jan 27.


Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis.

Kumar D, Branch BG, Pattillo CB, Hood J, Thoma S, Simpson S, Illum S, Arora N, Chidlow JH Jr, Langston W, Teng X, Lefer DJ, Patel RP, Kevil CG.

Proc Natl Acad Sci U S A. 2008 May 27;105(21):7540-5. doi: 10.1073/pnas.0711480105. Epub 2008 May 27.


Synthetic microvascular networks for quantitative analysis of particle adhesion.

Prabhakarpandian B, Pant K, Scott RC, Pattillo CB, Irimia D, Kiani MF, Sundaram S.

Biomed Microdevices. 2008 Aug;10(4):585-95. doi: 10.1007/s10544-008-9170-y. Erratum in: Biomed Microdevices. 2013 Dec;15(6):1087. Patillo, Christopher B [corrected to Pattillo, Christopher B].


Modeling oxygenation and selective delivery of drug carriers post-myocardial infarction.

Wang B, Scott RC, Pattillo CB, Prabhakarpandian B, Sundaram S, Kiani MF.

Adv Exp Med Biol. 2008;614:333-43. doi: 10.1007/978-0-387-74911-2_37.


Microvascular transport model predicts oxygenation changes in the infarcted heart after treatment.

Wang B, Scott RC, Pattillo CB, Prabhakarpandian B, Sundaram S, Kiani MF.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3732-9. Epub 2007 Oct 19.


Molecular mimicry in inducing DNA damage between HIV-1 Vpr and the anticancer agent, cisplatin.

Siddiqui K, Del Valle L, Morellet N, Cui J, Ghafouri M, Mukerjee R, Urbanska K, Fan S, Pattillo CB, Deshmane SL, Kiani MF, Ansari R, Khalili K, Roques BP, Reiss K, Bouaziz S, Amini S, Srinivasan A, Sawaya BE.

Oncogene. 2008 Jan 3;27(1):32-43. Epub 2007 Jul 23.


Anti-TNFA (TNF-alpha) treatment abrogates radiation-induced changes in vacular density and tissue oxygenation.

Ansari R, Gaber MW, Wang B, Pattillo CB, Miyamoto C, Kiani MF.

Radiat Res. 2007 Jan;167(1):80-6.


Targeted delivery of antibody conjugated liposomal drug carriers to rat myocardial infarction.

Scott RC, Wang B, Nallamothu R, Pattillo CB, Perez-Liz G, Issekutz A, Del Valle L, Wood GC, Kiani MF.

Biotechnol Bioeng. 2007 Mar 1;96(4):795-802.


A tumor vasculature targeted liposome delivery system for combretastatin A4: design, characterization, and in vitro evaluation.

Nallamothu R, Wood GC, Pattillo CB, Scott RC, Kiani MF, Moore BM, Thoma LA.

AAPS PharmSciTech. 2006 Apr 7;7(2):E32.


Targeting of the antivascular drug combretastatin to irradiated tumors results in tumor growth delay.

Pattillo CB, Sari-Sarraf F, Nallamothu R, Moore BM, Wood GC, Kiani MF.

Pharm Res. 2005 Jul;22(7):1117-20. Epub 2005 Jul 22.


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