Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Maternal diet-induced obesity alters muscle mitochondrial function in offspring without changing insulin sensitivity.

McMurray F, MacFarlane M, Kim K, Patten DA, Wei-LaPierre L, Fullerton MD, Harper ME.

FASEB J. 2019 Dec;33(12):13515-13526. doi: 10.1096/fj.201901150R. Epub 2019 Oct 3.


p53 Promotes chemoresponsiveness by regulating hexokinase II gene transcription and metabolic reprogramming in epithelial ovarian cancer.

Han CY, Patten DA, Lee SG, Parks RJ, Chan DW, Harper ME, Tsang BK.

Mol Carcinog. 2019 Nov;58(11):2161-2174. doi: 10.1002/mc.23106. Epub 2019 Sep 4.


The Role of Stabilin-1 in Lymphocyte Trafficking and Macrophage Scavenging in the Liver Microenvironment.

Patten DA, Shetty S.

Biomolecules. 2019 Jul 16;9(7). pii: E283. doi: 10.3390/biom9070283. Review.


Tumour-associated macrophages in hepatocellular carcinoma: Pressing the metabolic switch to prevent T cell responses.

O'Rourke JM, Patten DA, Shetty S.

J Hepatol. 2019 Aug;71(2):243-245. doi: 10.1016/j.jhep.2019.05.019. Epub 2019 Jun 14. No abstract available.


Mitochondrial adaptation in human mesenchymal stem cells following ionizing radiation.

Patten DA, Ouellet M, Allan DS, Germain M, Baird SD, Harper ME, Richardson RB.

FASEB J. 2019 Aug;33(8):9263-9278. doi: 10.1096/fj.201801483RR. Epub 2019 May 21.


Erratum: Novel Targets in the Immune Microenvironment of the Hepatic Sinusoids for Treating Liver Diseases.

Patten DA, Shepherd EL, Weston C, Shetty S.

Semin Liver Dis. 2019 May;39(2):e1. doi: 10.1055/s-0039-1688409. Epub 2019 Apr 16. No abstract available.


Novel Targets in the Immune Microenvironment of the Hepatic Sinusoids for Treating Liver Diseases.

Patten DA, Shepherd EL, Weston CJ, Shetty S.

Semin Liver Dis. 2019 May;39(2):111-123. doi: 10.1055/s-0039-1678727. Epub 2019 Mar 25. Review. Erratum in: Semin Liver Dis. 2019 May;39(2):e1.


Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3.

McBride S, Wei-LaPierre L, McMurray F, MacFarlane M, Qiu X, Patten DA, Dirksen RT, Harper ME.

Arch Biochem Biophys. 2019 Mar 15;663:239-248. doi: 10.1016/ Epub 2019 Jan 16.


More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking.

Patten DA, Shetty S.

Front Immunol. 2018 Dec 12;9:2904. doi: 10.3389/fimmu.2018.02904. eCollection 2018. Review.


Tumor metabolism regulating chemosensitivity in ovarian cancer.

Han CY, Patten DA, Richardson RB, Harper ME, Tsang BK.

Genes Cancer. 2018 May;9(5-6):155-175. doi: 10.18632/genesandcancer.176. Review.


IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation.

Nadeau L, Patten DA, Caron A, Garneau L, Pinault-Masson E, Foretz M, Haddad P, Anderson BG, Quinn LS, Jardine K, McBurney MW, Pistilli EE, Harper ME, Aguer C.

Biochim Biophys Acta Gen Subj. 2019 Feb;1863(2):395-407. doi: 10.1016/j.bbagen.2018.10.021. Epub 2018 Nov 15.


Atrial Fibrillation Is Associated With Impaired Atrial Mitochondrial Energetics and Supercomplex Formation in Adults With Type 2 Diabetes.

Kanaan GN, Patten DA, Redpath CJ, Harper ME.

Can J Diabetes. 2019 Feb;43(1):67-75.e1. doi: 10.1016/j.jcjd.2018.05.007. Epub 2018 May 31.


SCARF1: a multifaceted, yet largely understudied, scavenger receptor.

Patten DA.

Inflamm Res. 2018 Aug;67(8):627-632. doi: 10.1007/s00011-018-1154-7. Epub 2018 May 3. Review.


Chronic liver disease: scavenger hunt for novel therapies.

Patten DA, Shetty S.

Lancet. 2018 Jan 13;391(10116):104-105. doi: 10.1016/S0140-6736(17)32671-5. No abstract available.


SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress.

Patten DA, Kamarajah SK, Rose JM, Tickle J, Shepherd EL, Adams DH, Weston CJ, Shetty S.

Sci Rep. 2017 Dec 14;7(1):17600. doi: 10.1038/s41598-017-17928-4.


Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.

Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack RS, Al-Dirbashi OY, Dent R, McPherson R, Harper ME.

Int J Obes (Lond). 2018 Mar;42(3):353-362. doi: 10.1038/ijo.2017.286. Epub 2017 Nov 20.


Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.

Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME.

Redox Biol. 2018 Apr;14:509-521. doi: 10.1016/j.redox.2017.10.019. Epub 2017 Oct 26.


Commensal-derived OMVs elicit a mild proinflammatory response in intestinal epithelial cells.

Patten DA, Hussein E, Davies SP, Humphreys PN, Collett A.

Microbiology. 2017 May;163(5):702-711. doi: 10.1099/mic.0.000468. Epub 2017 May 22.


CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma.

Wadkin JCR, Patten DA, Kamarajah SK, Shepherd EL, Novitskaya V, Berditchevski F, Adams DH, Weston CJ, Shetty S.

Am J Physiol Gastrointest Liver Physiol. 2017 Aug 1;313(2):G138-G149. doi: 10.1152/ajpgi.00411.2016. Epub 2017 May 4.


Reactive Oxygen Species and Oxidative Stress in Obesity-Recent Findings and Empirical Approaches.

McMurray F, Patten DA, Harper ME.

Obesity (Silver Spring). 2016 Nov;24(11):2301-2310. doi: 10.1002/oby.21654. Review.


Human liver sinusoidal endothelial cells promote intracellular crawling of lymphocytes during recruitment: A new step in migration.

Patten DA, Wilson GK, Bailey D, Shaw RK, Jalkanen S, Salmi M, Rot A, Weston CJ, Adams DH, Shetty S.

Hepatology. 2017 Jan;65(1):294-309. doi: 10.1002/hep.28879. Epub 2016 Nov 25.


NOTCH1 mediates a switch between two distinct secretomes during senescence.

Hoare M, Ito Y, Kang TW, Weekes MP, Matheson NJ, Patten DA, Shetty S, Parry AJ, Menon S, Salama R, Antrobus R, Tomimatsu K, Howat W, Lehner PJ, Zender L, Narita M.

Nat Cell Biol. 2016 Sep;18(9):979-92. doi: 10.1038/ncb3397. Epub 2016 Aug 15.


Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.

Rantakari P, Patten DA, Valtonen J, Karikoski M, Gerke H, Dawes H, Laurila J, Ohlmeier S, Elima K, Hübscher SG, Weston CJ, Jalkanen S, Adams DH, Salmi M, Shetty S.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9298-303. doi: 10.1073/pnas.1604780113. Epub 2016 Jul 29.


Erratum to: Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Antoun G, McMurray F, Thrush AB, Patten DA, Peixoto AC, Slack RS, McPherson R, Dent R, Harper ME.

Diabetologia. 2016 Feb;59(2):396-7. doi: 10.1007/s00125-015-3821-3. No abstract available.


Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Antoun G, McMurray F, Thrush AB, Patten DA, Peixoto AC, Slack RS, McPherson R, Dent R, Harper ME.

Diabetologia. 2015 Dec;58(12):2861-6. doi: 10.1007/s00125-015-3772-8. Epub 2015 Sep 24. Erratum in: Diabetologia. 2016 Feb;59(2):396-7.


Lactobacillus-produced exopolysaccharides and their potential health benefits: a review.

Patten DA, Laws AP.

Benef Microbes. 2015;6(4):457-71. doi: 10.3920/BM2014.0117. Epub 2015 Feb 12. Review.


OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

Patten DA, Wong J, Khacho M, Soubannier V, Mailloux RJ, Pilon-Larose K, MacLaurin JG, Park DS, McBride HM, Trinkle-Mulcahy L, Harper ME, Germain M, Slack RS.

EMBO J. 2014 Nov 18;33(22):2676-91. doi: 10.15252/embj.201488349. Epub 2014 Oct 8.


The structure and immunomodulatory activity on intestinal epithelial cells of the EPSs isolated from Lactobacillus helveticus sp. Rosyjski and Lactobacillus acidophilus sp. 5e2.

Patten DA, Leivers S, Chadha MJ, Maqsood M, Humphreys PN, Laws AP, Collett A.

Carbohydr Res. 2014 Jan 30;384:119-27. doi: 10.1016/j.carres.2013.12.008. Epub 2013 Dec 12.


Exploring the immunomodulatory potential of microbial-associated molecular patterns derived from the enteric bacterial microbiota.

Patten DA, Collett A.

Microbiology. 2013 Aug;159(Pt 8):1535-1544. doi: 10.1099/mic.0.064717-0. Epub 2013 Jul 12. Review.


LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction.

Germain M, Nguyen AP, Khacho M, Patten DA, Screaton RA, Park DS, Slack RS.

Hum Mol Genet. 2013 Mar 1;22(5):952-62. doi: 10.1093/hmg/dds500. Epub 2012 Nov 27.


The Werner syndrome gene product (WRN): a repressor of hypoxia-inducible factor-1 activity.

Labbé A, Lafleur VN, Patten DA, Robitaille GA, Garand C, Lamalice L, Lebel M, Richard DE.

Exp Cell Res. 2012 Aug 15;318(14):1620-32. doi: 10.1016/j.yexcr.2012.04.010. Epub 2012 May 31.


Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species.

Patten DA, Lafleur VN, Robitaille GA, Chan DA, Giaccia AJ, Richard DE.

Mol Biol Cell. 2010 Sep 15;21(18):3247-57. doi: 10.1091/mbc.E10-01-0025. Epub 2010 Jul 21.


Reactive oxygen species: stuck in the middle of neurodegeneration.

Patten DA, Germain M, Kelly MA, Slack RS.

J Alzheimers Dis. 2010;20 Suppl 2:S357-67. doi: 10.3233/JAD-2010-100498. Review.


Case of the day. Angioblastic meningioma.

Auringer ST, Patten DA, Sumner TE.

J Ultrasound Med. 1993 Apr;12(4):242-3. No abstract available.


Supplemental Content

Loading ...
Support Center