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Items: 46

1.

Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability.

Barbieri F, Würth R, Pattarozzi A, Verduci I, Mazzola C, Cattaneo MG, Tonelli M, Solari A, Bajetto A, Daga A, Vicentini LM, Mazzanti M, Florio T.

Front Pharmacol. 2018 Aug 21;9:899. doi: 10.3389/fphar.2018.00899. eCollection 2018.

2.

Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G1-S Phase Progression in Human Glioblastoma Stem Cells.

Peretti M, Raciti FM, Carlini V, Verduci I, Sertic S, Barozzi S, Garré M, Pattarozzi A, Daga A, Barbieri F, Costa A, Florio T, Mazzanti M.

Mol Cancer Ther. 2018 Nov;17(11):2451-2461. doi: 10.1158/1535-7163.MCT-17-1223. Epub 2018 Aug 22.

PMID:
30135216
3.

Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects.

Baldassari S, Solari A, Zuccari G, Drava G, Pastorino S, Fucile C, Marini V, Daga A, Pattarozzi A, Ratto A, Ferrari A, Mattioli F, Barbieri F, Caviglioli G, Florio T.

Sci Rep. 2018 Mar 2;8(1):3929. doi: 10.1038/s41598-018-22054-w.

4.

In vitro and in vivo characterization of stem-like cells from canine osteosarcoma and assessment of drug sensitivity.

Gatti M, Solari A, Pattarozzi A, Campanella C, Thellung S, Maniscalco L, De Maria R, Würth R, Corsaro A, Bajetto A, Ratto A, Ferrari A, Daga A, Barbieri F, Florio T.

Exp Cell Res. 2018 Feb 1;363(1):48-64. doi: 10.1016/j.yexcr.2018.01.002. Epub 2018 Jan 4.

PMID:
29305964
5.

Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors.

Bajetto A, Pattarozzi A, Corsaro A, Barbieri F, Daga A, Bosio A, Gatti M, Pisaturo V, Sirito R, Florio T.

Front Cell Neurosci. 2017 Oct 13;11:312. doi: 10.3389/fncel.2017.00312. eCollection 2017.

6.

The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells.

Pattarozzi A, Carra E, Favoni RE, Würth R, Marubbi D, Filiberti RA, Mutti L, Florio T, Barbieri F, Daga A.

Stem Cell Res Ther. 2017 May 25;8(1):119. doi: 10.1186/s13287-017-0573-7.

7.

Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells.

Angeletti F, Fossati G, Pattarozzi A, Würth R, Solari A, Daga A, Masiello I, Barbieri F, Florio T, Comincini S.

Front Mol Neurosci. 2016 Oct 27;9:107. eCollection 2016.

8.

Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells.

Corsaro A, Bajetto A, Thellung S, Begani G, Villa V, Nizzari M, Pattarozzi A, Solari A, Gatti M, Pagano A, Würth R, Daga A, Barbieri F, Florio T.

Oncotarget. 2016 Jun 21;7(25):38638-38657. doi: 10.18632/oncotarget.9575.

9.

Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas.

Würth R, Barbieri F, Pattarozzi A, Gaudenzi G, Gatto F, Fiaschi P, Ravetti JL, Zona G, Daga A, Persani L, Ferone D, Vitale G, Florio T.

Mol Neurobiol. 2017 Sep;54(7):4879-4895. doi: 10.1007/s12035-016-0025-x. Epub 2016 Aug 11.

PMID:
27514754
10.

Canine osteosarcoma cell lines contain stem-like cancer cells: biological and pharmacological characterization.

Gatti M, Wurth R, Vito G, Pattarozzi A, Campanella C, Thellung S, Maniscalco L, De Maria R, Villa V, Corsaro A, Nizzari M, Bajetto A, Ratto A, Ferrari A, Barbieri F, Florio T.

Jpn J Vet Res. 2016 May;64(2):101-12.

PMID:
27506084
11.

The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.

Banelli B, Carra E, Barbieri F, Würth R, Parodi F, Pattarozzi A, Carosio R, Forlani A, Allemanni G, Marubbi D, Florio T, Daga A, Romani M.

Cell Cycle. 2015;14(21):3418-29. doi: 10.1080/15384101.2015.1090063.

12.

Molecular Pharmacology of Malignant Pleural Mesothelioma: Challenges and Perspectives From Preclinical and Clinical Studies.

Thellung S, Favoni RE, Würth R, Nizzari M, Pattarozzi A, Daga A, Florio T, Barbieri F.

Curr Drug Targets. 2016;17(7):824-49. Review.

PMID:
26240051
13.

In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors.

Barbieri F, Thellung S, Ratto A, Carra E, Marini V, Fucile C, Bajetto A, Pattarozzi A, Würth R, Gatti M, Campanella C, Vito G, Mattioli F, Pagano A, Daga A, Ferrari A, Florio T.

BMC Cancer. 2015 Apr 7;15:228. doi: 10.1186/s12885-015-1235-8.

14.

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current.

Gritti M, Würth R, Angelini M, Barbieri F, Peretti M, Pizzi E, Pattarozzi A, Carra E, Sirito R, Daga A, Curmi PM, Mazzanti M, Florio T.

Oncotarget. 2014 Nov 30;5(22):11252-68.

15.

Adiponectin as novel regulator of cell proliferation in human glioblastoma.

Porcile C, Di Zazzo E, Monaco ML, D'Angelo G, Passarella D, Russo C, Di Costanzo A, Pattarozzi A, Gatti M, Bajetto A, Zona G, Barbieri F, Oriani G, Moncharmont B, Florio T, Daniele A.

J Cell Physiol. 2014 Oct;229(10):1444-54. doi: 10.1002/jcp.24582.

PMID:
24648185
16.

Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages.

Giannoni P, Pietra G, Travaini G, Quarto R, Shyti G, Benelli R, Ottaggio L, Mingari MC, Zupo S, Cutrona G, Pierri I, Balleari E, Pattarozzi A, Calvaruso M, Tripodo C, Ferrarini M, de Totero D.

Haematologica. 2014 Jun;99(6):1078-87. doi: 10.3324/haematol.2013.091405. Epub 2014 Feb 21.

17.

Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity.

Gatti M, Pattarozzi A, Bajetto A, Würth R, Daga A, Fiaschi P, Zona G, Florio T, Barbieri F.

Toxicology. 2013 Dec 15;314(2-3):209-20. doi: 10.1016/j.tox.2013.10.003. Epub 2013 Oct 21.

PMID:
24157575
18.

Differential role of EGF and BFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensibility.

Bajetto A, Porcile C, Pattarozzi A, Scotti L, Aceto A, Daga A, Barbieri F, Florio T.

J Biol Regul Homeost Agents. 2013 Jan-Mar;27(1):143-54.

PMID:
23489694
19.

Peptide receptor targeting in cancer: the somatostatin paradigm.

Barbieri F, Bajetto A, Pattarozzi A, Gatti M, Würth R, Thellung S, Corsaro A, Villa V, Nizzari M, Florio T.

Int J Pept. 2013;2013:926295. doi: 10.1155/2013/926295. Epub 2013 Feb 7.

20.

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.

Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni RE, Florio T, Daga A.

Cell Cycle. 2013 Feb 1;12(3):491-500. doi: 10.4161/cc.23372. Epub 2013 Jan 16.

21.

Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

Würth R, Pattarozzi A, Gatti M, Bajetto A, Corsaro A, Parodi A, Sirito R, Massollo M, Marini C, Zona G, Fenoglio D, Sambuceti G, Filaci G, Daga A, Barbieri F, Florio T.

Cell Cycle. 2013 Jan 1;12(1):145-56. doi: 10.4161/cc.23050. Epub 2012 Dec 19.

22.

Receptor tyrosine kinase inhibitors and cytotoxic drugs affect pleural mesothelioma cell proliferation: insight into EGFR and ERK1/2 as antitumor targets.

Barbieri F, Würth R, Favoni RE, Pattarozzi A, Gatti M, Ratto A, Ferrari A, Bajetto A, Florio T.

Biochem Pharmacol. 2011 Nov 15;82(10):1467-77. doi: 10.1016/j.bcp.2011.07.073. Epub 2011 Jul 20.

PMID:
21787763
23.

An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease.

Giannoni P, Scaglione S, Quarto R, Narcisi R, Parodi M, Balleari E, Barbieri F, Pattarozzi A, Florio T, Ferrini S, Corte G, de Totero D.

Haematologica. 2011 Jul;96(7):1015-23. doi: 10.3324/haematol.2010.029736. Epub 2011 Apr 12.

24.

Expression of CXCR7 chemokine receptor in human meningioma cells and in intratumoral microvasculature.

Würth R, Barbieri F, Bajetto A, Pattarozzi A, Gatti M, Porcile C, Zona G, Ravetti JL, Spaziante R, Florio T.

J Neuroimmunol. 2011 May;234(1-2):115-23. doi: 10.1016/j.jneuroim.2011.01.006. Epub 2011 Feb 11.

PMID:
21316111
25.

In vivo and in vitro response to octreotide LAR in a TSH-secreting adenoma: characterization of somatostatin receptor expression and role of subtype 5.

Gatto F, Barbieri F, Castelletti L, Arvigo M, Pattarozzi A, Annunziata F, Saveanu A, Minuto F, Castellan L, Zona G, Florio T, Ferone D.

Pituitary. 2011 Jun;14(2):141-7. doi: 10.1007/s11102-010-0271-2.

PMID:
21086053
26.

Gefitinib targets EGFR dimerization and ERK1/2 phosphorylation to inhibit pleural mesothelioma cell proliferation.

Favoni RE, Pattarozzi A, Lo Casto M, Barbieri F, Gatti M, Paleari L, Bajetto A, Porcile C, Gaudino G, Mutti L, Corte G, Florio T.

Curr Cancer Drug Targets. 2010 Mar;10(2):176-91.

PMID:
20088784
27.

Differential efficacy of SSTR1, -2, and -5 agonists in the inhibition of C6 glioma growth in nude mice.

Barbieri F, Pattarozzi A, Gatti M, Aiello C, Quintero A, Lunardi G, Bajetto A, Ferrari A, Culler MD, Florio T.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1078-88. doi: 10.1152/ajpendo.00292.2009. Epub 2009 Aug 25.

28.

Different response of human glioma tumor-initiating cells to epidermal growth factor receptor kinase inhibitors.

Griffero F, Daga A, Marubbi D, Capra MC, Melotti A, Pattarozzi A, Gatti M, Bajetto A, Porcile C, Barbieri F, Favoni RE, Lo Casto M, Zona G, Spaziante R, Florio T, Corte G.

J Biol Chem. 2009 Mar 13;284(11):7138-48. doi: 10.1074/jbc.M807111200. Epub 2009 Jan 14.

29.

The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization.

Iuliano R, Raso C, Quintiero A, Pera IL, Pichiorri F, Palumbo T, Palmieri D, Pattarozzi A, Florio T, Viglietto G, Trapasso F, Croce CM, Fusco A.

J Biochem. 2009 Mar;145(3):377-85. doi: 10.1093/jb/mvn175. Epub 2009 Jan 3.

PMID:
19122201
30.

Overexpression of stromal cell-derived factor 1 and its receptor CXCR4 induces autocrine/paracrine cell proliferation in human pituitary adenomas.

Barbieri F, Bajetto A, Stumm R, Pattarozzi A, Porcile C, Zona G, Dorcaratto A, Ravetti JL, Minuto F, Spaziante R, Schettini G, Ferone D, Florio T.

Clin Cancer Res. 2008 Aug 15;14(16):5022-32. doi: 10.1158/1078-0432.CCR-07-4717.

31.

Somatostatin receptors 1, 2, and 5 cooperate in the somatostatin inhibition of C6 glioma cell proliferation in vitro via a phosphotyrosine phosphatase-eta-dependent inhibition of extracellularly regulated kinase-1/2.

Barbieri F, Pattarozzi A, Gatti M, Porcile C, Bajetto A, Ferrari A, Culler MD, Florio T.

Endocrinology. 2008 Sep;149(9):4736-46. doi: 10.1210/en.2007-1762. Epub 2008 Jun 19.

PMID:
18566118
32.

17beta-estradiol promotes breast cancer cell proliferation-inducing stromal cell-derived factor-1-mediated epidermal growth factor receptor transactivation: reversal by gefitinib pretreatment.

Pattarozzi A, Gatti M, Barbieri F, Würth R, Porcile C, Lunardi G, Ratto A, Favoni R, Bajetto A, Ferrari A, Florio T.

Mol Pharmacol. 2008 Jan;73(1):191-202. Epub 2007 Oct 24.

PMID:
17959712
33.

SDF-1 controls pituitary cell proliferation through the activation of ERK1/2 and the Ca2+-dependent, cytosolic tyrosine kinase Pyk2.

Massa A, Casagrande S, Bajetto A, Porcile C, Barbieri F, Thellung S, Arena S, Pattarozzi A, Gatti M, Corsaro A, Robello M, Schettini G, Florio T.

Ann N Y Acad Sci. 2006 Dec;1090:385-98.

PMID:
17384283
34.

CXC receptor and chemokine expression in human meningioma: SDF1/CXCR4 signaling activates ERK1/2 and stimulates meningioma cell proliferation.

Barbieri F, Bajetto A, Porcile C, Pattarozzi A, Massa A, Lunardi G, Zona G, Dorcaratto A, Ravetti JL, Spaziante R, Schettini G, Florio T.

Ann N Y Acad Sci. 2006 Dec;1090:332-43.

PMID:
17384278
35.

Role of stromal cell-derived factor 1 (SDF1/CXCL12) in regulating anterior pituitary function.

Barbieri F, Bajetto A, Porcile C, Pattarozzi A, Schettini G, Florio T.

J Mol Endocrinol. 2007 Mar;38(3):383-9. Review.

PMID:
17339401
36.

CXCR4 and SDF1 expression in human meningiomas: a proliferative role in tumoral meningothelial cells in vitro.

Bajetto A, Barbieri F, Pattarozzi A, Dorcaratto A, Porcile C, Ravetti JL, Zona G, Spaziante R, Schettini G, Florio T.

Neuro Oncol. 2007 Jan;9(1):3-11. Epub 2006 Nov 15.

37.

An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta.

Arena S, Pattarozzi A, Massa A, Esteve JP, Iuliano R, Fusco A, Susini C, Florio T.

Mol Endocrinol. 2007 Jan;21(1):229-46. Epub 2006 Oct 4.

PMID:
17021051
38.

Chemokine stromal cell-derived factor 1alpha induces proliferation and growth hormone release in GH4C1 rat pituitary adenoma cell line through multiple intracellular signals.

Florio T, Casagrande S, Diana F, Bajetto A, Porcile C, Zona G, Thellung S, Arena S, Pattarozzi A, Corsaro A, Spaziante R, Robello M, Schettini G.

Mol Pharmacol. 2006 Feb;69(2):539-46. Epub 2005 Oct 28.

PMID:
16258074
39.

The phosphotyrosine phosphatase eta mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2.

Massa A, Barbieri F, Aiello C, Iuliano R, Arena S, Pattarozzi A, Corsaro A, Villa V, Fusco A, Zona G, Spaziante R, Schettini G, Florio T.

Ann N Y Acad Sci. 2004 Dec;1030:264-74.

PMID:
15659806
40.

Somatostatin receptor subtype-dependent regulation of nitric oxide release: involvement of different intracellular pathways.

Arena S, Pattarozzi A, Corsaro A, Schettini G, Florio T.

Mol Endocrinol. 2005 Jan;19(1):255-67. Epub 2004 Sep 23.

PMID:
15388796
41.

The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation.

Massa A, Barbieri F, Aiello C, Arena S, Pattarozzi A, Pirani P, Corsaro A, Iuliano R, Fusco A, Zona G, Spaziante R, Florio T, Schettini G.

J Biol Chem. 2004 Jul 9;279(28):29004-12. Epub 2004 Apr 30.

42.

Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro.

Florio T, Thellung S, Corsaro A, Bocca L, Arena S, Pattarozzi A, Villa V, Massa A, Diana F, Schettini D, Barbieri F, Ravetti JL, Spaziante R, Giusti M, Schettini G.

Clin Endocrinol (Oxf). 2003 Jul;59(1):115-28.

PMID:
12807513
43.

Basic fibroblast growth factor activates endothelial nitric-oxide synthase in CHO-K1 cells via the activation of ceramide synthesis.

Florio T, Arena S, Pattarozzi A, Thellung S, Corsaro A, Villa V, Massa A, Diana F, Spoto G, Forcella S, Damonte G, Filocamo M, Benatti U, Schettini G.

Mol Pharmacol. 2003 Feb;63(2):297-310.

PMID:
12527801
44.

Nitric oxide production stimulated by the basic fibroblast growth factor requires the synthesis of ceramide.

Arena S, Pattarozzi A, Thellung S, Villa V, Corsaro A, Massa A, Diana F, Spoto G, Forcella S, Damonte G, Filocamo M, Benatti U, Schettini G, Florioa T.

Ann N Y Acad Sci. 2002 Nov;973:94-104.

PMID:
12485842
45.

[The activation of the phosphotyrosine phosphatase eta is responsible for the somatostatin inhibition of PCCl3 thyroid cell proliferation].

Florio T, Arena S, Thellung S, Iuliano R, Corsaro A, Massa A, Villa V, Pattarozzi A, Diana F, Fusco A, Schettini G.

Minerva Endocrinol. 2001 Dec;26(4):277-83. Italian.

PMID:
11782716
46.

The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation.

Florio T, Arena S, Thellung S, Iuliano R, Corsaro A, Massa A, Pattarozzi A, Bajetto A, Trapasso F, Fusco A, Schettini G.

Mol Endocrinol. 2001 Oct;15(10):1838-52.

PMID:
11579215

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