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Items: 1 to 50 of 89

1.

GlyGen: Computational and Informatics Resources for Glycoscience.

York WS, Mazumder R, Ranzinger R, Edwards N, Kahsay R, Aoki-Kinoshita KF, Campbell MP, Cummings RD, Feizi T, Martin M, Natale DA, Packer NH, Woods RJ, Agarwal G, Arpinar S, Bhat S, Blake J, Castro LJG, Fochtman B, Gildersleeve J, Goldman R, Holmes X, Jain V, Kulkarni S, Mahadik R, Mehta A, Mousavi R, Nakarakommula S, Navelkar R, Pattabiraman N, Pierce MJ, Ross K, Vasudev P, Vora J, Williamson T, Zhang W.

Glycobiology. 2020 Jan 28;30(2):72-73. doi: 10.1093/glycob/cwz080. No abstract available.

PMID:
31616925
2.

Dysregulated calcium homeostasis prevents plasma membrane repair in Anoctamin 5/TMEM16E-deficient patient muscle cells.

Chandra G, Defour A, Mamchoui K, Pandey K, Mishra S, Mouly V, Sreetama S, Mahad Ahmad M, Mahjneh I, Morizono H, Pattabiraman N, Menon AK, Jaiswal JK.

Cell Death Discov. 2019 Jul 18;5:118. doi: 10.1038/s41420-019-0197-z. eCollection 2019.

3.

Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway.

Chen J, Zaidi S, Rao S, Chen JS, Phan L, Farci P, Su X, Shetty K, White J, Zamboni F, Wu X, Rashid A, Pattabiraman N, Mazumder R, Horvath A, Wu RC, Li S, Xiao C, Deng CX, Wheeler DA, Mishra B, Akbani R, Mishra L.

Gastroenterology. 2018 Jan;154(1):195-210. doi: 10.1053/j.gastro.2017.09.007. Epub 2017 Sep 15.

4.

Discovery of novel inhibitors of multidrug-resistant Acinetobacter baumannii.

Soojhawon I, Pattabiraman N, Tsang A, Roth AL, Kang E, Noble SM.

Bioorg Med Chem. 2017 Oct 15;25(20):5477-5482. doi: 10.1016/j.bmc.2017.08.014. Epub 2017 Aug 9.

PMID:
28830719
5.

Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model.

Bagh MB, Peng S, Chandra G, Zhang Z, Singh SP, Pattabiraman N, Liu A, Mukherjee AB.

Nat Commun. 2017 Mar 7;8:14612. doi: 10.1038/ncomms14612.

6.

Impact of germline and somatic missense variations on drug binding sites.

Yan C, Pattabiraman N, Goecks J, Lam P, Nayak A, Pan Y, Torcivia-Rodriguez J, Voskanian A, Wan Q, Mazumder R.

Pharmacogenomics J. 2017 Mar;17(2):128-136. doi: 10.1038/tpj.2015.97. Epub 2016 Jan 26.

7.

Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.

Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, Lallas CD, Gupta S, Ellsworth E, Blackmon S, Ertel A, Fortina P, Leiby B, Xia G, Rui H, Hoang DT, Gomella LG, Cingolani G, Njar V, Pattabiraman N, Calabretta B, Nevalainen MT.

Mol Cancer Ther. 2015 Aug;14(8):1777-93. doi: 10.1158/1535-7163.MCT-14-0883. Epub 2015 May 29.

8.

Modulating Acinetobacter baumannii biofilm development with molecules containing 3,4,5-trimethoxy-N,N',N'-trimethylbenzohydrazide moiety.

Sambanthamoorthy K, Hickman M, Pattabiraman N, Palys T, Wagar EJ.

Bioorg Med Chem Lett. 2015;25(10):2238-42. doi: 10.1016/j.bmcl.2015.03.005. Epub 2015 Mar 10.

PMID:
25881818
9.

Structure-function analysis of hepatitis C virus envelope glycoproteins E1 and E2.

Nayak A, Pattabiraman N, Fadra N, Goldman R, Kosakovsky Pond SL, Mazumder R.

J Biomol Struct Dyn. 2015;33(8):1682-94. doi: 10.1080/07391102.2014.967300. Epub 2014 Oct 15.

10.

Identification of small molecules inhibiting diguanylate cyclases to control bacterial biofilm development.

Sambanthamoorthy K, Luo C, Pattabiraman N, Feng X, Koestler B, Waters CM, Palys TJ.

Biofouling. 2014 Jan;30(1):17-28. doi: 10.1080/08927014.2013.832224. Epub 2013 Oct 11.

11.

An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation.

Kirilyuk A, Shimoji M, Catania J, Sahu G, Pattabiraman N, Giordano A, Albanese C, Mocchetti I, Toretsky JA, Uversky VN, Avantaggiati ML.

PLoS One. 2012;7(11):e48243. doi: 10.1371/journal.pone.0048243. Epub 2012 Nov 1.

12.

Amino acid residues at the N- and C-termini are essential for the folding of active human butyrylcholinesterase polypeptide.

Naik RS, Pattabiraman N, Patel KA, Doctor BP, Saxena A.

Chem Biol Interact. 2013 Mar 25;203(1):24-9. doi: 10.1016/j.cbi.2012.09.018. Epub 2012 Oct 6.

PMID:
23044488
13.

Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase.

Belinskaya T, Pattabiraman N, diTargiani R, Choi M, Saxena A.

Biochim Biophys Acta. 2012 May;1824(5):701-10. doi: 10.1016/j.bbapap.2012.02.007. Epub 2012 Feb 28.

PMID:
22401958
14.

Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1.

Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, Suñé C, Cvekl A, Wu K, Jiang J, Wang C, Pestell RG.

J Biol Chem. 2010 Dec 17;285(51):40342-50. doi: 10.1074/jbc.M110.156141. Epub 2010 Oct 18.

15.

Y124 at the peripheral anionic site is important for the reactivation of nerve agent-inhibited acetylcholinesterase by H oximes.

Luo C, Chambers C, Pattabiraman N, Tong M, Tipparaju P, Saxena A.

Biochem Pharmacol. 2010 Nov 1;80(9):1427-36. doi: 10.1016/j.bcp.2010.07.020. Epub 2010 Jul 22.

PMID:
20655881
16.

Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS.

Ariyannur PS, Moffett JR, Manickam P, Pattabiraman N, Arun P, Nitta A, Nabeshima T, Madhavarao CN, Namboodiri AM.

Brain Res. 2010 Jun 4;1335:1-13. doi: 10.1016/j.brainres.2010.04.008. Epub 2010 Apr 10.

PMID:
20385109
17.

Carprofen induction of p75NTR-dependent apoptosis via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.

Khwaja FS, Quann EJ, Pattabiraman N, Wynne S, Djakiew D.

Mol Cancer Ther. 2008 Nov;7(11):3539-45. doi: 10.1158/1535-7163.MCT-08-0512. Epub 2008 Oct 30.

18.

Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen.

Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R.

Antimicrob Agents Chemother. 2008 Sep;52(9):3385-93. doi: 10.1128/AAC.01508-07. Epub 2008 Jul 7. Erratum in: Antimicrob Agents Chemother. 2009 Jan;53(1):341.

19.

Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.

Velu CS, Niture SK, Doneanu CE, Pattabiraman N, Srivenugopal KS.

Biochemistry. 2007 Jul 3;46(26):7765-80. Epub 2007 Jun 8.

20.

Mutational analysis of aspartoacylase: implications for Canavan disease.

Hershfield JR, Pattabiraman N, Madhavarao CN, Namboodiri MA.

Brain Res. 2007 May 7;1148:1-14. Epub 2007 Mar 3.

21.

Multiple enzyme activities of flavivirus proteins.

Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K.

Novartis Found Symp. 2006;277:74-84; discussion 84-6, 251-3. Review.

PMID:
17319155
22.

Hormonal control of androgen receptor function through SIRT1.

Fu M, Liu M, Sauve AA, Jiao X, Zhang X, Wu X, Powell MJ, Yang T, Gu W, Avantaggiati ML, Pattabiraman N, Pestell TG, Wang F, Quong AA, Wang C, Pestell RG.

Mol Cell Biol. 2006 Nov;26(21):8122-35. Epub 2006 Aug 21.

23.

Selectivity and potency of cyclin-dependent kinase inhibitors.

Sridhar J, Akula N, Pattabiraman N.

AAPS J. 2006 Mar 24;8(1):E204-21. Review.

24.

In-silico screening using flexible ligand binding pockets: a molecular dynamics-based approach.

Sivanesan D, Rajnarayanan RV, Doherty J, Pattabiraman N.

J Comput Aided Mol Des. 2005 Apr;19(4):213-28.

PMID:
16163449
25.

3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation.

Yin Y, Yuan H, Wang C, Pattabiraman N, Rao M, Pestell RG, Glazer RI.

Mol Endocrinol. 2006 Feb;20(2):268-78. Epub 2005 Sep 8.

PMID:
16150867
26.

Web-based interface facilitating sequence-to-structure analysis of BLAST alignment reports.

Ganesan N, Bennett NF, Velauthapillai M, Pattabiraman N, Squier R, Kalyanasundaram B.

Biotechniques. 2005 Aug;39(2):186, 188. No abstract available.

27.

Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators.

Mandal AK, Ray R, Zhang Z, Chowdhury B, Pattabiraman N, Mukherjee AB.

J Biol Chem. 2005 Sep 23;280(38):32897-904. Epub 2005 Aug 1.

28.

Identification of novel angiogenesis inhibitors.

Sridhar J, Akula N, Sivanesan D, Narasimhan M, Rathinavelu A, Pattabiraman N.

Bioorg Med Chem Lett. 2005 Sep 15;15(18):4125-9.

PMID:
15993586
29.

Analysis of the hormone-binding domain of steroid receptors using chimeras generated by homologous recombination.

Martinez ED, Pattabiraman N, Danielsen M.

Exp Cell Res. 2005 Aug 15;308(2):320-33.

PMID:
15936754
30.

A systematic search method for the identification of tightly packed transmembrane parallel alpha-helices.

Akula N, Pattabiraman N.

J Biomol Struct Dyn. 2005 Jun;22(6):625-34.

PMID:
15842168
31.

Homology model of the CDK1/cyclin B complex.

McGrath CF, Pattabiraman N, Kellogg GE, Lemcke T, Kunick C, Sausville EA, Zaharevitz DW, Gussio R.

J Biomol Struct Dyn. 2005 Apr;22(5):493-502.

PMID:
15702922
32.

"Teaching old drugs to kill new bugs": structure-based discovery of anti-SARS drugs.

Rajnarayanan RV, Dakshanamurthy S, Pattabiraman N.

Biochem Biophys Res Commun. 2004 Aug 20;321(2):370-8.

PMID:
15358186
33.

Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR.

Akula N, Bhalla J, Sridhar J, Pattabiraman N.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3397-400.

PMID:
15177440
34.

Uteroglobin represses allergen-induced inflammatory response by blocking PGD2 receptor-mediated functions.

Mandal AK, Zhang Z, Ray R, Choi MS, Chowdhury B, Pattabiraman N, Mukherjee AB.

J Exp Med. 2004 May 17;199(10):1317-30.

35.

A composite chiral pair of rotational bands in the odd-A nucleus 135Nd.

Zhu S, Garg U, Nayak BK, Ghugre SS, Pattabiraman NS, Fossan DB, Koike T, Starosta K, Vaman C, Janssens RV, Chakrawarthy RS, Whitehead M, Macchiavelli AO, Frauendorf S.

Phys Rev Lett. 2003 Sep 26;91(13):132501. Epub 2003 Sep 25.

PMID:
14525299
36.

Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.

Wang C, Pattabiraman N, Zhou JN, Fu M, Sakamaki T, Albanese C, Li Z, Wu K, Hulit J, Neumeister P, Novikoff PM, Brownlee M, Scherer PE, Jones JG, Whitney KD, Donehower LA, Harris EL, Rohan T, Johns DC, Pestell RG.

Mol Cell Biol. 2003 Sep;23(17):6159-73.

37.

Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors.

Kuang D, Yao Y, Wang M, Pattabiraman N, Kotra LP, Hampson DR.

J Biol Chem. 2003 Oct 24;278(43):42551-9. Epub 2003 Aug 11.

38.

Molecular modeling and mutagenesis of the ligand-binding pocket of the mGlu3 subtype of metabotropic glutamate receptor.

Yao Y, Pattabiraman N, Michne WF, Huang XP, Hampson DR.

J Neurochem. 2003 Aug;86(4):947-57.

39.

Molecular modeling and dynamics studies of HIV-1 kissing loop structures.

Pattabiraman N, Martinez HM, Shapiro BA.

J Biomol Struct Dyn. 2002 Dec;20(3):397-412.

PMID:
12437378
40.

Analysis of ligand-macromolecule contacts: computational methods.

Pattabiraman N.

Curr Med Chem. 2002 Mar;9(5):609-21. Review.

PMID:
11945127
41.

Uteroglobin/Clara cell 10-kDa family of proteins: nomenclature committee report.

Klug J, Beier HM, Bernard A, Chilton BS, Fleming TP, Lehrer RI, Miele L, Pattabiraman N, Singh G.

Ann N Y Acad Sci. 2000;923:348-54. Review. No abstract available.

PMID:
11193777
42.

Crystal structure analysis of recombinant human uteroglobin and molecular modeling of ligand binding.

Pattabiraman N, Matthews JH, Ward KB, Mantile-Selvaggi G, Miele L, Mukherjee AB.

Ann N Y Acad Sci. 2000;923:113-27.

PMID:
11193750
43.

Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition.

Gussio R, Zaharevitz DW, McGrath CF, Pattabiraman N, Kellogg GE, Schultz C, Link A, Kunick C, Leost M, Meijer L, Sausville EA.

Anticancer Drug Des. 2000 Feb;15(1):53-66.

PMID:
10888036
44.

The RESID Database of protein structure modifications and the NRL-3D Sequence-Structure Database.

Garavelli JS, Hou Z, Pattabiraman N, Stephens RM.

Nucleic Acids Res. 2001 Jan 1;29(1):199-201.

45.
46.

Uteroglobin: a novel cytokine?

Mukherjee AB, Kundu GC, Mantile-Selvaggi G, Yuan CJ, Mandal AK, Chattopadhyay S, Zheng F, Pattabiraman N, Zhang Z.

Cell Mol Life Sci. 1999 May;55(5):771-87. Review.

PMID:
10379362
47.

Uteroglobin: physiological role in normal glomerular function uncovered by targeted disruption of the uteroglobin gene in mice.

Mukherjee AB, Kundu GC, Mandal AK, Pattabiraman N, Yuan CJ, Zhang Z.

Am J Kidney Dis. 1998 Dec;32(6):1106-20. Review.

PMID:
9856533
48.

Ion-RNA interactions in the RNA pseudoknot of a ribosomal frameshifting site: molecular modeling studies.

Le SY, Chen JH, Pattabiraman N, Maizel JV Jr.

J Biomol Struct Dyn. 1998 Aug;16(1):1-11.

PMID:
9745889
49.
50.

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