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Items: 7

1.

Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells.

Patsali P, Turchiano G, Papasavva P, Romito M, Loucari CC, Stephanou C, Christou S, Sitarou M, Mussolino C, Cornu TI, Antoniou MN, Lederer CW, Cathomen T, Kleanthous M.

Haematologica. 2019 Nov;104(11):e497-e501. doi: 10.3324/haematol.2018.215178. Epub 2019 Apr 19. No abstract available.

2.

Disruptive Technology: CRISPR/Cas-Based Tools and Approaches.

Patsali P, Kleanthous M, Lederer CW.

Mol Diagn Ther. 2019 Apr;23(2):187-200. doi: 10.1007/s40291-019-00391-4. Review.

3.

Short-hairpin RNA against aberrant HBBIVSI-110(G>A) mRNA restores β-globin levels in a novel cell model and acts as mono- and combination therapy for β-thalassemia in primary hematopoietic stem cells.

Patsali P, Papasavva P, Stephanou C, Christou S, Sitarou M, Antoniou MN, Lederer CW, Kleanthous M.

Haematologica. 2018 Sep;103(9):e419-e423. doi: 10.3324/haematol.2018.189357. Epub 2018 Apr 26. No abstract available.

4.

Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.

Loucari CC, Patsali P, van Dijk TB, Stephanou C, Papasavva P, Zanti M, Kurita R, Nakamura Y, Christou S, Sitarou M, Philipsen S, Lederer CW, Kleanthous M.

Hum Gene Ther Methods. 2018 Feb;29(1):60-74. doi: 10.1089/hgtb.2017.190.

5.

Suitability of small diagnostic peripheral-blood samples for cell-therapy studies.

Stephanou C, Papasavva P, Zachariou M, Patsali P, Epitropou M, Ladas P, Al-Abdulla R, Christou S, Antoniou MN, Lederer CW, Kleanthous M.

Cytotherapy. 2017 Feb;19(2):311-326. doi: 10.1016/j.jcyt.2016.11.007.

PMID:
28088294
6.

Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.

Christodoulou I, Patsali P, Stephanou C, Antoniou M, Kleanthous M, Lederer CW.

Gene Ther. 2016 Jan;23(1):113-8. doi: 10.1038/gt.2015.60. Epub 2015 Jun 30.

7.

Enhanced central nervous system transduction with lentiviral vectors pseudotyped with RVG/HIV-1gp41 chimeric envelope glycoproteins.

Trabalza A, Eleftheriadou I, Sgourou A, Liao TY, Patsali P, Lee H, Mazarakis ND.

J Virol. 2014 Mar;88(5):2877-90. doi: 10.1128/JVI.03376-13. Epub 2013 Dec 26.

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