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Items: 1 to 50 of 340

1.

Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.

Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, Sgambato A, Patrono C, FitzGerald GA, Yu Y, Patrignani P.

J Pharmacol Exp Ther. 2019 Sep;370(3):416-426. doi: 10.1124/jpet.119.259382. Epub 2019 Jun 27.

PMID:
31248980
2.

Role of aspirin in primary prevention of cardiovascular disease.

Patrono C, Baigent C.

Nat Rev Cardiol. 2019 Jun 26. doi: 10.1038/s41569-019-0225-y. [Epub ahead of print] Review.

PMID:
31243390
3.

A NOVEL BIOLOGICAL DOSIMETRY ASSAY AS A POTENTIAL TOOL FOR TRIAGE DOSE ASSESSMENT IN CASE OF LARGE-SCALE RADIOLOGICAL EMERGENCY.

Testa A, Palma V, Patrono C.

Radiat Prot Dosimetry. 2019 Feb 6. doi: 10.1093/rpd/ncz001. [Epub ahead of print]

PMID:
30726995
4.

Gustav Born and life as "a series of ripples widening out from an original centre".

Patrono C.

Platelets. 2018 Dec;29(8):761-762. doi: 10.1080/09537104.2018.1535289. Epub 2018 Oct 30. Review. No abstract available.

PMID:
30376389
5.

Off-Pump Coronary Artery Bypass Grafting: 30 Years of Debate.

Gaudino M, Angelini GD, Antoniades C, Bakaeen F, Benedetto U, Calafiore AM, Di Franco A, Di Mauro M, Fremes SE, Girardi LN, Glineur D, Grau J, He GW, Patrono C, Puskas JD, Ruel M, Schwann TA, Tam DY, Tatoulis J, Tranbaugh R, Vallely M, Zenati MA, Mack M, Taggart DP; Arterial Grafting International Consortium (ATLANTIC) Alliance.

J Am Heart Assoc. 2018 Aug 21;7(16):e009934. doi: 10.1161/JAHA.118.009934. No abstract available.

6.

Aspirin, platelet inhibition and cancer prevention.

Patrignani P, Patrono C.

Platelets. 2018 Dec;29(8):779-785. doi: 10.1080/09537104.2018.1492105. Epub 2018 Jul 9. Review.

PMID:
29985750
7.

The Aspirin Regimens in Essential Thrombocythemia (ARES) phase II randomized trial design: Implementation of the serum thromboxane B2 assay as an evaluation tool of different aspirin dosing regimens in the clinical setting.

De Stefano V, Rocca B, Tosetto A, Soldati D, Petrucci G, Beggiato E, Bertozzi I, Betti S, Carli G, Carpenedo M, Cattaneo D, Cavalca V, Dragani A, Elli E, Finazzi G, Iurlo A, Lanzarone G, Lissandrini L, Palandri F, Paoli C, Rambaldi A, Ranalli P, Randi ML, Ricco A, Rossi E, Ruggeri M, Specchia G, Timillero A, Turnu L, Vianelli N, Vannucchi AM, Rodeghiero F, Patrono C.

Blood Cancer J. 2018 Jun 1;8(6):49. doi: 10.1038/s41408-018-0078-3.

8.

Analysis of Radiation-Induced Chromosomal Aberrations on a Cell-by-Cell Basis after Alpha-Particle Microbeam Irradiation: Experimental Data and Simulations.

Testa A, Ballarini F, Giesen U, Gil OM, Carante MP, Tello J, Langner F, Rabus H, Palma V, Pinto M, Patrono C.

Radiat Res. 2018 Jun;189(6):597-604. doi: 10.1667/RR15005.1. Epub 2018 Apr 6.

PMID:
29624483
9.

Protein oxidative damage and redox imbalance induced by ionising radiation in CHO cells.

Pietraforte D, Paulicelli E, Patrono C, Gambardella L, Scorza G, Testa A, Fattibene P.

Free Radic Res. 2018 Apr;52(4):465-479. doi: 10.1080/10715762.2018.1446529. Epub 2018 Mar 16.

PMID:
29546780
10.

Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis.

Rocca B, Fox KAA, Ajjan RA, Andreotti F, Baigent C, Collet JP, Grove EL, Halvorsen S, Huber K, Morais J, Patrono C, Rubboli A, Seljeflot I, Sibbing D, Siegbahn A, Ten Berg J, Vilahur G, Verheugt FWA, Wallentin L, Weiss TW, Wojta J, Storey RF.

Eur Heart J. 2018 May 14;39(19):1672-1686f. doi: 10.1093/eurheartj/ehy066. No abstract available.

PMID:
29509886
11.

Effects of gastroprotectant drugs for the prevention and treatment of peptic ulcer disease and its complications: a meta-analysis of randomised trials.

Scally B, Emberson JR, Spata E, Reith C, Davies K, Halls H, Holland L, Wilson K, Bhala N, Hawkey C, Hochberg M, Hunt R, Laine L, Lanas A, Patrono C, Baigent C.

Lancet Gastroenterol Hepatol. 2018 Apr;3(4):231-241. doi: 10.1016/S2468-1253(18)30037-2. Epub 2018 Feb 21.

12.

Fighting residual cardiovascular risk in stable patients with atherosclerotic vascular disease: COMPASS in context.

Patrono C.

Cardiovasc Res. 2017 Dec 1;113(14):e61-e63. doi: 10.1093/cvr/cvx209. No abstract available.

PMID:
29186439
13.

Mechanisms, Consequences, and Prevention of Coronary Graft Failure.

Gaudino M, Antoniades C, Benedetto U, Deb S, Di Franco A, Di Giammarco G, Fremes S, Glineur D, Grau J, He GW, Marinelli D, Ohmes LB, Patrono C, Puskas J, Tranbaugh R, Girardi LN, Taggart DP; ATLANTIC (Arterial Grafting International Consortium) Alliance.

Circulation. 2017 Oct 31;136(18):1749-1764. doi: 10.1161/CIRCULATIONAHA.117.027597. Review.

PMID:
29084780
14.

Exposing primary rat retina cell cultures to γ-rays: An in vitro model for evaluating radiation responses.

Gaddini L, Balduzzi M, Campa A, Esposito G, Malchiodi-Albedi F, Patrono C, Matteucci A.

Exp Eye Res. 2018 Jan;166:21-28. doi: 10.1016/j.exer.2017.09.009. Epub 2017 Sep 27.

PMID:
28958589
15.

Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis.

Patrono C, Morais J, Baigent C, Collet JP, Fitzgerald D, Halvorsen S, Rocca B, Siegbahn A, Storey RF, Vilahur G.

J Am Coll Cardiol. 2017 Oct 3;70(14):1760-1776. doi: 10.1016/j.jacc.2017.08.037. Review.

16.

Featuring: Prof Carlo Patrono.

Patrono C.

Eur Cardiol. 2017 Aug;12(1):63-66. doi: 10.15420/ecr.2017.12.1.63. No abstract available.

17.

On-pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens.

Cavalca V, Rocca B, Veglia F, Petrucci G, Porro B, Myasoedova V, De Cristofaro R, Turnu L, Bonomi A, Songia P, Cavallotti L, Zanobini M, Camera M, Alamanni F, Parolari A, Patrono C, Tremoli E.

Clin Pharmacol Ther. 2017 Nov;102(5):849-858. doi: 10.1002/cpt.702. Epub 2017 Jul 29.

PMID:
28379623
18.

In Silico Modeling of the Antiplatelet Pharmacodynamics of Low-dose Aspirin in Health and Disease.

Giaretta A, Rocca B, Di Camillo B, Toffolo GM, Patrono C.

Clin Pharmacol Ther. 2017 Nov;102(5):823-831. doi: 10.1002/cpt.694. Epub 2017 May 30.

PMID:
28378909
19.

Coxibs, Traditional NSAIDs, and Cardiovascular Safety Post-PRECISION: What We Thought We Knew Then and What We Think We Know Now.

Patrono C, Baigent C.

Clin Pharmacol Ther. 2017 Aug;102(2):238-245. doi: 10.1002/cpt.696. Epub 2017 May 26. Review.

PMID:
28378879
20.

Low-Dose Aspirin Acetylates Cyclooxygenase-1 in Human Colorectal Mucosa: Implications for the Chemoprevention of Colorectal Cancer.

Patrignani P, Sacco A, Sostres C, Bruno A, Dovizio M, Piazuelo E, Di Francesco L, Contursi A, Zucchelli M, Schiavone S, Tacconelli S, Patrono C, Lanas A.

Clin Pharmacol Ther. 2017 Jul;102(1):52-61. doi: 10.1002/cpt.639. Epub 2017 Apr 4.

PMID:
28139830
21.

Type 2 Diabetes, Obesity, and Aspirin Responsiveness.

Patrono C, Rocca B.

J Am Coll Cardiol. 2017 Feb 14;69(6):613-615. doi: 10.1016/j.jacc.2016.11.049. Epub 2017 Jan 11. No abstract available.

22.

Should the 1h algorithm for rule in and rule out of acute myocardial infarction be used universally?

Crea F, Jaffe AS, Collinson PO, Hamm CW, Lindahl B, Mills NL, Thygesen K, Mueller C, Patrono C, Roffi M; 2015 ESC NSTE-ACS Guidelines Task Force.

Eur Heart J. 2016 Nov 21;37(44):3316-3323. doi: 10.1093/eurheartj/ehw282. No abstract available.

PMID:
28007934
23.

[2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)].

Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S.

G Ital Cardiol (Rome). 2016 Oct;17(10):831-872. doi: 10.1714/2464.25804. Italian. No abstract available.

PMID:
27869901
24.

Patient-independent variables affecting the assessment of aspirin responsiveness by serum thromboxane measurement.

Petrucci G, Rizzi A, Cavalca V, Habib A, Pitocco D, Veglia F, Ranalli P, Zaccardi F, Pagliaccia F, Tremoli E, Patrono C, Rocca B.

Thromb Haemost. 2016 Oct 28;116(5):891-896. Epub 2016 Jul 21.

PMID:
27440714
25.

RENEB - Running the European Network of biological dosimetry and physical retrospective dosimetry.

Kulka U, Abend M, Ainsbury E, Badie C, Barquinero JF, Barrios L, Beinke C, Bortolin E, Cucu A, De Amicis A, Domínguez I, Fattibene P, Frøvig AM, Gregoire E, Guogyte K, Hadjidekova V, Jaworska A, Kriehuber R, Lindholm C, Lloyd D, Lumniczky K, Lyng F, Meschini R, Mörtl S, Della Monaca S, Monteiro Gil O, Montoro A, Moquet J, Moreno M, Oestreicher U, Palitti F, Pantelias G, Patrono C, Piqueret-Stephan L, Port M, Prieto MJ, Quintens R, Ricoul M, Romm H, Roy L, Sáfrány G, Sabatier L, Sebastià N, Sommer S, Terzoudi G, Testa A, Thierens H, Turai I, Trompier F, Valente M, Vaz P, Voisin P, Vral A, Woda C, Zafiropoulos D, Wojcik A.

Int J Radiat Biol. 2017 Jan;93(1):2-14. doi: 10.1080/09553002.2016.1230239. Epub 2016 Oct 6.

PMID:
27707245
26.

Aspirin and Cancer.

Patrignani P, Patrono C.

J Am Coll Cardiol. 2016 Aug 30;68(9):967-76. doi: 10.1016/j.jacc.2016.05.083. Review.

27.

RENEB accident simulation exercise.

Brzozowska B, Ainsbury E, Baert A, Beaton-Green L, Barrios L, Barquinero JF, Bassinet C, Beinke C, Benedek A, Beukes P, Bortolin E, Buraczewska I, Burbidge C, De Amicis A, De Angelis C, Della Monaca S, Depuydt J, De Sanctis S, Dobos K, Domene MM, Domínguez I, Facco E, Fattibene P, Frenzel M, Monteiro Gil O, Gonon G, Gregoire E, Gruel G, Hadjidekova V, Hatzi VI, Hristova R, Jaworska A, Kis E, Kowalska M, Kulka U, Lista F, Lumniczky K, Martínez-López W, Meschini R, Moertl S, Moquet J, Noditi M, Oestreicher U, Orta Vázquez ML, Palma V, Pantelias G, Montoro Pastor A, Patrono C, Piqueret-Stephan L, Quattrini MC, Regalbuto E, Ricoul M, Roch-Lefevre S, Roy L, Sabatier L, Sarchiapone L, Sebastià N, Sommer S, Sun M, Suto Y, Terzoudi G, Trompier F, Vral A, Wilkins R, Zafiropoulos D, Wieser A, Woda C, Wojcik A.

Int J Radiat Biol. 2017 Jan;93(1):75-80. doi: 10.1080/09553002.2016.1206230. Epub 2016 Aug 25.

PMID:
27559844
29.

Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons.

Ainsbury E, Badie C, Barnard S, Manning G, Moquet J, Abend M, Antunes AC, Barrios L, Bassinet C, Beinke C, Bortolin E, Bossin L, Bricknell C, Brzoska K, Buraczewska I, Castaño CH, Čemusová Z, Christiansson M, Cordero SM, Cosler G, Monaca SD, Desangles F, Discher M, Dominguez I, Doucha-Senf S, Eakins J, Fattibene P, Filippi S, Frenzel M, Georgieva D, Gregoire E, Guogyte K, Hadjidekova V, Hadjiiska L, Hristova R, Karakosta M, Kis E, Kriehuber R, Lee J, Lloyd D, Lumniczky K, Lyng F, Macaeva E, Majewski M, Vanda Martins S, McKeever SW, Meade A, Medipally D, Meschini R, M'kacher R, Gil OM, Montero A, Moreno M, Noditi M, Oestreicher U, Oskamp D, Palitti F, Palma V, Pantelias G, Pateux J, Patrono C, Pepe G, Port M, Prieto MJ, Quattrini MC, Quintens R, Ricoul M, Roy L, Sabatier L, Sebastià N, Sholom S, Sommer S, Staynova A, Strunz S, Terzoudi G, Testa A, Trompier F, Valente M, Hoey OV, Veronese I, Wojcik A, Woda C.

Int J Radiat Biol. 2017 Jan;93(1):99-109. doi: 10.1080/09553002.2016.1206233. Epub 2016 Jul 20. Erratum in: Int J Radiat Biol. 2017 Jan;93(1):x.

PMID:
27437830
30.

Cardiovascular effects of cyclooxygenase-2 inhibitors: a mechanistic and clinical perspective.

Patrono C.

Br J Clin Pharmacol. 2016 Oct;82(4):957-64. doi: 10.1111/bcp.13048. Epub 2016 Jul 18. Review.

31.

Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.

Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P.

Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655.

32.

Clinical Perspectives and Pearls from the 2015 ESC NSTE-ACS Guidelines.

Roffi M, Gencer B, Storey RF, Andreotti F, Patrono C.

Curr Cardiol Rep. 2016 May;18(5):48. doi: 10.1007/s11886-016-0722-0. Review.

PMID:
27068306
33.

Cardiovascular Effects of Nonsteroidal Anti-inflammatory Drugs.

Patrono C.

Curr Cardiol Rep. 2016 Mar;18(3):25. doi: 10.1007/s11886-016-0702-4. Review.

PMID:
26841787
34.

CardioPulse: What's new in the 2015 European Society of Cardiology Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation.

Roffi M, Patrono C, Zamorano JL.

Eur Heart J. 2016 Jan 14;37(3):206-7. doi: 10.1093/eurheartj/ehv654. No abstract available.

PMID:
26768211
35.

[2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation].

Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S.

Kardiol Pol. 2015;73(12):1207-94. doi: 10.5603/KP.2015.0243. Polish. No abstract available.

36.

2015 ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-segment Elevation.

Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S.

Rev Esp Cardiol (Engl Ed). 2015 Dec;68(12):1125. doi: 10.1016/j.rec.2015.10.009. No abstract available.

37.

In Vivo Platelet Activation and Aspirin Responsiveness in Type 1 Diabetes.

Zaccardi F, Rizzi A, Petrucci G, Ciaffardini F, Tanese L, Pagliaccia F, Cavalca V, Ciminello A, Habib A, Squellerio I, Rizzo P, Tremoli E, Rocca B, Pitocco D, Patrono C.

Diabetes. 2016 Feb;65(2):503-9. doi: 10.2337/db15-0936. Epub 2015 Oct 15.

38.

Questions and answers on antithrombotic therapy: a companion document of the 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation†.

Collet JP, Roffi M, Mueller C, Valgimigli M, Patrono C, Baumgartner H, Gaemperli O, Zamorano JL.

Eur Heart J. 2015 Aug 29. pii: ehv407. [Epub ahead of print] No abstract available.

PMID:
26320115
39.

Questions and answers on diagnosis and risk assessment: a companion document of the 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation†.

Authors:, Mueller C, Patrono C, Valgimigli M, Collet JP, Roffi M; Authors.

Eur Heart J. 2015 Aug 29. pii: ehv409. [Epub ahead of print] No abstract available.

PMID:
26320114
40.

Questions and answers on coronary revascularization: a companion document of the 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation.

Valgimigli M, Patrono C, Collet JP, Mueller C, Roffi M; Authors.

Eur Heart J. 2015 Aug 29. pii: ehv408. [Epub ahead of print] No abstract available.

PMID:
26320111
41.

2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC).

Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S; ESC Scientific Document Group .

Eur Heart J. 2016 Jan 14;37(3):267-315. doi: 10.1093/eurheartj/ehv320. Epub 2015 Aug 29. No abstract available.

42.

Platelet progenitors: the hidden drug target.

Rocca B, Patrono C.

Eur Heart J. 2015 Dec 1;36(45):3211-3. doi: 10.1093/eurheartj/ehv366. Epub 2015 Aug 1. No abstract available.

PMID:
26233852
43.

Antithrombotic therapy in the elderly: expert position paper of the European Society of Cardiology Working Group on Thrombosis.

Andreotti F, Rocca B, Husted S, Ajjan RA, ten Berg J, Cattaneo M, Collet JP, De Caterina R, Fox KA, Halvorsen S, Huber K, Hylek EM, Lip GY, Montalescot G, Morais J, Patrono C, Verheugt FW, Wallentin L, Weiss TW, Storey RF; ESC Thrombosis Working Group.

Eur Heart J. 2015 Dec 7;36(46):3238-49. doi: 10.1093/eurheartj/ehv304. Epub 2015 Jul 9. Review. No abstract available.

PMID:
26163482
44.

The Multifaceted Clinical Readouts of Platelet Inhibition by Low-Dose Aspirin.

Patrono C.

J Am Coll Cardiol. 2015 Jul 7;66(1):74-85. doi: 10.1016/j.jacc.2015.05.012. Review.

45.

Homocysteine, methylenetetrahydrofolate reductase, folate status and atherothrombosis: A mechanistic and clinical perspective.

Santilli F, Davì G, Patrono C.

Vascul Pharmacol. 2016 Mar;78:1-9. doi: 10.1016/j.vph.2015.06.009. Epub 2015 Jun 22. Review.

PMID:
26111718
46.

'BioQuaRT' project: design of a novel in situ protocol for the simultaneous visualisation of chromosomal aberrations and micronuclei after irradiation at microbeam facilities.

Patrono C, Monteiro Gil O, Giesen U, Langner F, Pinto M, Rabus H, Testa A.

Radiat Prot Dosimetry. 2015 Sep;166(1-4):197-9. doi: 10.1093/rpd/ncv160. Epub 2015 Apr 15.

PMID:
25877532
47.

Polymorphisms in base excision repair genes: Breast cancer risk and individual radiosensitivity.

Patrono C, Sterpone S, Testa A, Cozzi R.

World J Clin Oncol. 2014 Dec 10;5(5):874-82. doi: 10.5306/wjco.v5.i5.874. Review.

48.

Role of clinical pharmacology in the development of antiplatelet drugs.

Patrono C.

Clin Ther. 2014 Dec 1;36(12):2096-2111. doi: 10.1016/j.clinthera.2014.10.012. Epub 2014 Nov 20. Review.

PMID:
25467192
49.

Cyclooxygenase inhibitors: From pharmacology to clinical read-outs.

Patrignani P, Patrono C.

Biochim Biophys Acta. 2015 Apr;1851(4):422-32. doi: 10.1016/j.bbalip.2014.09.016. Epub 2014 Sep 28. Review.

PMID:
25263946
50.

Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action.

Patrignani P, Tacconelli S, Piazuelo E, Di Francesco L, Dovizio M, Sostres C, Marcantoni E, Guillem-Llobat P, Del Boccio P, Zucchelli M, Patrono C, Lanas A.

J Thromb Haemost. 2014 Aug;12(8):1320-30. doi: 10.1111/jth.12637. Epub 2014 Jul 18.

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