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Items: 1 to 50 of 1046

1.

P2X3 Receptor Antagonism Reduces the Occurrence of Apnoeas in Newborn Rats.

Katayama PL, Abdala AP, Charles I, Pijacka W, Salgado HC, Gever J, Ford AP, Paton JFR.

Respir Physiol Neurobiol. 2020 Apr 4:103438. doi: 10.1016/j.resp.2020.103438. [Epub ahead of print]

PMID:
32259688
2.

A consensus statement on the use of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in relation to COVID-19 (corona virus disease 2019).

Talreja H, Tan J, Dawes M, Supershad S, Rabindranath K, Fisher J, Valappil S, van der Merwe V, Wong L, van der Merwe W, Paton J.

N Z Med J. 2020 Apr 3;133(1512):85-87.

PMID:
32242182
3.

Clarity of the rhythmic brainstem.

Paton JFR.

J Physiol. 2020 Mar 20. doi: 10.1113/JP279732. [Epub ahead of print] No abstract available.

PMID:
32196662
4.

Retrograde blood flow in the internal jugular veins of humans with hypertension may have implications for cerebral arterial blood flow.

Rodrigues JCL, Strelko G, Warnert EAH, Burchell AE, Neumann S, Ratcliffe LEK, Harris AD, Chant B, Bowles R, Nightingale AK, Wise RG, Paton JFR, Hart EC.

Eur Radiol. 2020 Mar 10. doi: 10.1007/s00330-020-06752-6. [Epub ahead of print]

PMID:
32157411
5.

Identification of signal peptide features for substrate specificity in human Sec62/Sec63-dependent ER protein import.

Schorr S, Nguyen D, Haßdenteufel S, Nagaraj N, Cavalié A, Greiner M, Weissgerber P, Loi M, Paton AW, Paton JC, Molinari M, Förster F, Dudek J, Lang S, Helms V, Zimmermann R.

FEBS J. 2020 Mar 4. doi: 10.1111/febs.15274. [Epub ahead of print]

PMID:
32133789
6.

Host-glycan metabolism is regulated by a species-conserved two-component system in Streptococcus pneumoniae.

Andreassen PR, Trappetti C, Minhas V, Nielsen FD, Pakula K, Paton JC, Jørgensen MG.

PLoS Pathog. 2020 Mar 4;16(3):e1008332. doi: 10.1371/journal.ppat.1008332. eCollection 2020 Mar.

7.

Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum.

Poothong J, Pottekat A, Siriin M, Campos AR, Paton AW, Paton JC, Lagunas-Acosta J, Chen Z, Swift M, Volkmann N, Hanein D, Yong J, Kaufman RJ.

Blood. 2020 Mar 3. pii: blood.2019002867. doi: 10.1182/blood.2019002867. [Epub ahead of print]

PMID:
32128578
8.

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress.

Grey MJ, Cloots E, Simpson MS, LeDuc N, Serebrenik YV, De Luca H, De Sutter D, Luong P, Thiagarajah JR, Paton AW, Paton JC, Seeliger MA, Eyckerman S, Janssens S, Lencer WI.

J Cell Biol. 2020 Feb 3;219(2). pii: e201904048. doi: 10.1083/jcb.201904048.

PMID:
31985747
9.

Therapeutic Relevance of Elevated Blood Pressure After Ischemic Stroke in the Hypertensive Rats.

Thakkar PC, McGregor AL, Barber PA, Paton JFR, Barrett CJ, McBryde FD.

Hypertension. 2020 Mar;75(3):740-747. doi: 10.1161/HYPERTENSIONAHA.119.14219. Epub 2020 Jan 20.

PMID:
31957520
10.

The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats.

Felippe ISA, Müller CJT, Siqueira AA, Dos Santos L, Cavadino A, Paton JFR, Beijamini V, Sampaio KN.

Toxicol Appl Pharmacol. 2020 Jan 15;389:114879. doi: 10.1016/j.taap.2020.114879. Epub 2020 Jan 10.

PMID:
31931016
11.

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow.

Marina N, Christie IN, Korsak A, Doronin M, Brazhe A, Hosford PS, Wells JA, Sheikhbahaei S, Humoud I, Paton JFR, Lythgoe MF, Semyanov A, Kasparov S, Gourine AV.

Nat Commun. 2020 Jan 9;11(1):131. doi: 10.1038/s41467-019-13956-y.

12.

Zibotentan, an Endothelin A Receptor Antagonist, Prevents Amyloid-β-Induced Hypertension and Maintains Cerebral Perfusion.

Palmer JC, Tayler HM, Dyer L, Kehoe PG, Paton JFR, Love S.

J Alzheimers Dis. 2020;73(3):1185-1199. doi: 10.3233/JAD-190630.

13.

Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation.

Taverner WK, Jacobus EJ, Christianson J, Champion B, Paton AW, Paton JC, Su W, Cawood R, Seymour LW, Lei-Rossmann J.

Mol Ther Oncolytics. 2019 Sep 28;15:117-130. doi: 10.1016/j.omto.2019.09.003. eCollection 2019 Dec 20.

14.

Pneumococcal Vaccines.

Briles DE, Paton JC, Mukerji R, Swiatlo E, Crain MJ.

Microbiol Spectr. 2019 Nov;7(6). doi: 10.1128/microbiolspec.GPP3-0028-2018. Review.

PMID:
31858954
15.

Active expiratory oscillator regulates nasofacial and oral motor activities in rats.

de Britto AA, Magalhães KS, da Silva MP, Paton JFR, Moraes DJA.

Exp Physiol. 2020 Feb;105(2):379-392. doi: 10.1113/EP088046. Epub 2020 Jan 14.

PMID:
31820827
16.

Optimal solid state neurons.

Abu-Hassan K, Taylor JD, Morris PG, Donati E, Bortolotto ZA, Indiveri G, Paton JFR, Nogaret A.

Nat Commun. 2019 Dec 3;10(1):5309. doi: 10.1038/s41467-019-13177-3.

17.

Efficacy of Electrical Baroreflex Activation Is Independent of Peripheral Chemoreceptor Modulation.

Heusser K, Thöne A, Lipp A, Menne J, Beige J, Reuter H, Hoffmann F, Halbach M, Eckert S, Wallbach M, Koziolek M, Haarmann H, Joyner MJ, Paton JFR, Diedrich A, Haller H, Jordan J, Tank J.

Hypertension. 2020 Jan;75(1):257-264. doi: 10.1161/HYPERTENSIONAHA.119.13925. Epub 2019 Dec 2.

PMID:
31786986
18.

Investigation and Treatment of High Blood Pressure in Young People: Too Much Medicine or Appropriate Risk Reduction?

Hinton TC, Adams ZH, Baker RP, Hope KA, Paton JFR, Hart EC, Nightingale AK.

Hypertension. 2020 Jan;75(1):16-22. doi: 10.1161/HYPERTENSIONAHA.119.13820. Epub 2019 Nov 18.

PMID:
31735086
19.

Enhancing respiratory sinus arrhythmia increases cardiac output in rats with left ventricular dysfunction.

O'Callaghan EL, Lataro RM, Roloff EL, Chauhan AS, Salgado HC, Duncan E, Nogaret A, Paton JFR.

J Physiol. 2020 Feb;598(3):455-471. doi: 10.1113/JP277293. Epub 2019 Dec 9.

PMID:
31721215
20.

Repaired coarctation of the aorta, persistent arterial hypertension and the selfish brain.

Rodrigues JCL, Jaring MFR, Werndle MC, Mitrousi K, Lyen SM, Nightingale AK, Hamilton MCK, Curtis SL, Manghat NE, Paton JFR, Hart EC.

J Cardiovasc Magn Reson. 2019 Nov 7;21(1):68. doi: 10.1186/s12968-019-0578-8.

21.

Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin.

Álvarez RS, Jancic C, Garimano N, Sacerdoti F, Paton AW, Paton JC, Ibarra C, Amaral MM.

Toxins (Basel). 2019 Nov 7;11(11). pii: E648. doi: 10.3390/toxins11110648.

22.

A6 neurons simultaneously modulate active expiration and upper airway resistance in rats.

Magalhães KS, de Britto AA, Paton JFR, Moraes DJA.

Exp Physiol. 2020 Jan;105(1):53-64. doi: 10.1113/EP088164. Epub 2019 Nov 20.

PMID:
31675759
23.

The Role of Zinc Efflux during Acinetobacter baumannii Infection.

Alquethamy SF, Adams FG, Naidu V, Khorvash M, Pederick VG, Zang M, Paton JC, Paulsen IT, Hassan KA, Cain AK, McDevitt CA, Eijkelkamp BA.

ACS Infect Dis. 2020 Jan 10;6(1):150-158. doi: 10.1021/acsinfecdis.9b00351. Epub 2019 Nov 8.

PMID:
31658418
24.

Cerebral Blood Flow Response to Simulated Hypovolemia in Essential Hypertension: A Magnetic Resonance Imaging Study.

Neumann S, Burchell AE, Rodrigues JCL, Lawton CB, Burden D, Underhill M, Kobetić MD, Adams ZH, Brooks JCW, Nightingale AK, Paton JFR, Hamilton MCK, Hart EC.

Hypertension. 2019 Dec;74(6):1391-1398. doi: 10.1161/HYPERTENSIONAHA.119.13229. Epub 2019 Oct 28.

25.

9-Azido Analogues of Three Sialic Acid Forms for Metabolic Remodeling of Cell-Surface Sialoglycans.

Cheng B, Dong L, Zhu Y, Huang R, Sun Y, You Q, Song Q, Paton JC, Paton AW, Chen X.

ACS Chem Biol. 2019 Oct 18;14(10):2141-2147. doi: 10.1021/acschembio.9b00556. Epub 2019 Oct 4.

PMID:
31584261
26.

Update of the European paediatric respiratory medicine syllabus.

Primhak R, Tabin N, Beydon N, Bhatt J, Eber E, Hammer J, Martinez-Gimeno A, Midulla F, Nenna R, Paton J, Ross Russell R.

Breathe (Sheff). 2019 Sep;15(3):173-180. doi: 10.1183/20734735.0188-2019. Review.

27.

Hypertensive Response to Ischemic Stroke in the Normotensive Wistar Rat.

Thakkar P, McGregor A, Barber PA, Paton JFR, Barrett C, McBryde F.

Stroke. 2019 Sep;50(9):2522-2530. doi: 10.1161/STROKEAHA.119.026459. Epub 2019 Aug 6.

PMID:
31449479
28.

Dietary zinc and the control of Streptococcus pneumoniae infection.

Eijkelkamp BA, Morey JR, Neville SL, Tan A, Pederick VG, Cole N, Singh PP, Ong CY, Gonzalez de Vega R, Clases D, Cunningham BA, Hughes CE, Comerford I, Brazel EB, Whittall JJ, Plumptre CD, McColl SR, Paton JC, McEwan AG, Doble PA, McDevitt CA.

PLoS Pathog. 2019 Aug 22;15(8):e1007957. doi: 10.1371/journal.ppat.1007957. eCollection 2019 Aug.

29.

Centrally acting adrenomedullin in the long-term potentiation of sympathetic vasoconstrictor activity induced by intermittent hypoxia in rats.

Zoccal DB, Colombari DSA, Colombari E, Flor KC, da Silva MP, Costa-Silva JH, Machado BH, Moraes DJA, Murphy D, Paton JFR.

Exp Physiol. 2019 Sep;104(9):1371-1383. doi: 10.1113/EP087613. Epub 2019 Aug 5.

PMID:
31328309
30.

Denervated or Not? That Remains the Question for Renal Denervation.

Paton JFR.

Hypertension. 2019 Sep;74(3):493-494. doi: 10.1161/HYPERTENSIONAHA.119.12779. Epub 2019 Jul 22. No abstract available.

PMID:
31327273
31.

Textured shoe insoles to improve balance performance in adults with diabetic peripheral neuropathy: study protocol for a randomised controlled trial.

Hatton AL, Gane EM, Maharaj JN, Burns J, Paton J, Kerr G, Rome K.

BMJ Open. 2019 Jul 17;9(7):e026240. doi: 10.1136/bmjopen-2018-026240.

32.

Heart failure developed after myocardial infarction does not affect gut microbiota composition in the rat.

Lataro RM, Imori PFM, Santos ES, Silva LEV, Duarte RTD, Silva CAA, Falcão JP, Paton JFR, Salgado HC.

Am J Physiol Gastrointest Liver Physiol. 2019 Sep 1;317(3):G342-G348. doi: 10.1152/ajpgi.00018.2019. Epub 2019 Jul 17.

PMID:
31314548
33.

SMRT sequencing reveals differential patterns of methylation in two O111:H- STEC isolates from a hemolytic uremic syndrome outbreak in Australia.

Forde BM, McAllister LJ, Paton JC, Paton AW, Beatson SA.

Sci Rep. 2019 Jul 1;9(1):9436. doi: 10.1038/s41598-019-45760-5.

34.

Clustering of IRE1α depends on sensing ER stress but not on its RNase activity.

Ricci D, Marrocco I, Blumenthal D, Dibos M, Eletto D, Vargas J, Boyle S, Iwamoto Y, Chomistek S, Paton JC, Paton AW, Argon Y.

FASEB J. 2019 Sep;33(9):9811-9827. doi: 10.1096/fj.201801240RR. Epub 2019 Jun 14.

PMID:
31199681
35.

Renal Denervation Update From the International Sympathetic Nervous System Summit: JACC State-of-the-Art Review.

Kiuchi MG, Esler MD, Fink GD, Osborn JW, Banek CT, Böhm M, Denton KM, DiBona GF, Everett TH 4th, Grassi G, Katholi RE, Knuepfer MM, Kopp UC, Lefer DJ, Lohmeier TE, May CN, Mahfoud F, Paton JFR, Schmieder RE, Pellegrino PR, Sharabi Y, Schlaich MP.

J Am Coll Cardiol. 2019 Jun 18;73(23):3006-3017. doi: 10.1016/j.jacc.2019.04.015. Review.

PMID:
31196459
36.

Proinsulin misfolding is an early event in the progression to type 2 diabetes.

Arunagiri A, Haataja L, Pottekat A, Pamenan F, Kim S, Zeltser LM, Paton AW, Paton JC, Tsai B, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P.

Elife. 2019 Jun 11;8. pii: e44532. doi: 10.7554/eLife.44532.

37.

The Logic of Carotid Body Connectivity to the Brain.

Zera T, Moraes DJA, da Silva MP, Fisher JP, Paton JFR.

Physiology (Bethesda). 2019 Jul 1;34(4):264-282. doi: 10.1152/physiol.00057.2018. Review.

PMID:
31165684
38.

Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity.

David SC, Norton T, Tyllis T, Wilson JJ, Singleton EV, Laan Z, Davies J, Hirst TR, Comerford I, McColl SR, Paton JC, Alsharifi M.

Nat Microbiol. 2019 Aug;4(8):1316-1327. doi: 10.1038/s41564-019-0443-4. Epub 2019 May 20.

PMID:
31110357
39.

Intermittent Exposure to Chlorpyrifos Differentially Impacts Neuroreflex Control of Cardiorespiratory Function in Rats.

Batista TJ, Minassa VS, Aitken AV, Jara BT, Felippe ISA, Beijamini V, Paton JFR, Dos Santos L, Sampaio KN.

Cardiovasc Toxicol. 2019 Dec;19(6):548-564. doi: 10.1007/s12012-019-09528-7.

PMID:
31098944
40.

Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance.

Ashton JL, Trew ML, LeGrice IJ, Paterson DJ, Paton JF, Gillis AM, Smaill BH.

J Physiol. 2019 Jul;597(13):3297-3313. doi: 10.1113/JP276876. Epub 2019 May 26.

PMID:
31087820
41.

On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat.

Farmer DGS, Pracejus N, Dempsey B, Turner A, Bokiniec P, Paton JFR, Pickering AE, Burguet J, Andrey P, Goodchild AK, McAllen RM, McMullan S.

J Physiol. 2019 Jul;597(13):3407-3423. doi: 10.1113/JP277661. Epub 2019 Jun 2.

PMID:
31077360
42.

Enhanced safety and immunogenicity of a pneumococcal surface antigen A mutant whole-cell inactivated pneumococcal vaccine.

David SC, Laan Z, Minhas V, Chen AY, Davies J, Hirst TR, McColl SR, Alsharifi M, Paton JC.

Immunol Cell Biol. 2019 Sep;97(8):726-739. doi: 10.1111/imcb.12257. Epub 2019 May 23.

PMID:
31050022
43.

Streptococcus pneumoniae Capsular Polysaccharide.

Paton JC, Trappetti C.

Microbiol Spectr. 2019 Mar;7(2). doi: 10.1128/microbiolspec.GPP3-0019-2018. Review.

PMID:
30977464
44.

Two Sides of the Same Coin?-Treatment of Chronic Asthma in Children and Adults.

Chung LP, Paton JY.

Front Pediatr. 2019 Mar 11;7:62. doi: 10.3389/fped.2019.00062. eCollection 2019. Review.

45.

Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy.

Van Krieken R, Mehta N, Wang T, Zheng M, Li R, Gao B, Ayaub E, Ask K, Paton JC, Paton AW, Austin RC, Krepinsky JC.

J Biol Chem. 2019 May 10;294(19):7755-7768. doi: 10.1074/jbc.RA118.006939. Epub 2019 Mar 26.

PMID:
30914477
46.
47.

Biologics for paediatric severe asthma: trick or TREAT?

Saglani S, Bush A, Carroll W, Cunningham S, Fleming L, Gaillard E, Gupta A, Murray C, Nagakumar P, Paton J, Roberts G, Seddon P, Sinha I.

Lancet Respir Med. 2019 Apr;7(4):294-296. doi: 10.1016/S2213-2600(19)30045-1. Epub 2019 Feb 26. No abstract available.

48.

Mepolizumab in adolescents with severe eosinophilic asthma not eligible for omalizumab: one center's early clinical experience.

Weir E, Paton J.

J Asthma. 2020 May;57(5):521-524. doi: 10.1080/02770903.2019.1579833. Epub 2019 Feb 22. No abstract available.

PMID:
30795693
49.

Selective Inactivation of Intracellular BiP/GRP78 Attenuates Endothelial Inflammation and Permeability in Acute Lung Injury.

Leonard A, Grose V, Paton AW, Paton JC, Yule DI, Rahman A, Fazal F.

Sci Rep. 2019 Feb 14;9(1):2096. doi: 10.1038/s41598-018-38312-w.

50.

The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating.

Ziska A, Tatzelt J, Dudek J, Paton AW, Paton JC, Zimmermann R, Haßdenteufel S.

Biol Open. 2019 Mar 5;8(3). pii: bio040691. doi: 10.1242/bio.040691.

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