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Items: 25


Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.

Kumar G, Patlolla JM, Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Singh A, Gillaspy A, Lightfoot S, Steele VE, Kopelovich L, Rao CV.

Am J Cancer Res. 2016 May 1;6(5):894-909. eCollection 2016.


Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo.

Madka V, Mohammed A, Li Q, Zhang Y, Biddick L, Patlolla JM, Lightfoot S, Towner RA, Wu XR, Steele VE, Kopelovich L, Rao CV.

Cancer Prev Res (Phila). 2016 Jan;9(1):53-62. doi: 10.1158/1940-6207.CAPR-15-0199. Epub 2015 Nov 17.


Early and delayed intervention with rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice.

Patlolla JM, Kopelovich L, Qian L, Zhang Y, Kumar G, Madka V, Mohammed A, Biddick L, Sadeghi M, Lightfoot S, Rao CV.

Oncol Rep. 2015 Dec;34(6):2925-34. doi: 10.3892/or.2015.4277. Epub 2015 Sep 16.


Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression.

Mohammed A, Janakiram NB, Madka V, Brewer M, Ritchie RL, Lightfoot S, Kumar G, Sadeghi M, Patlolla JM, Yamada HY, Cruz-Monserrate Z, May R, Houchen CW, Steele VE, Rao CV.

Oncotarget. 2015 Jun 20;6(17):15524-39.


Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.

Mohammed A, Janakiram NB, Madka V, Ritchie RL, Brewer M, Biddick L, Patlolla JM, Sadeghi M, Lightfoot S, Steele VE, Rao CV.

Cancer Prev Res (Phila). 2014 Dec;7(12):1198-209. doi: 10.1158/1940-6207.CAPR-14-0176. Epub 2014 Sep 23.


Chemoprevention of urothelial cell carcinoma growth and invasion by the dual COX-LOX inhibitor licofelone in UPII-SV40T transgenic mice.

Madka V, Mohammed A, Li Q, Zhang Y, Patlolla JM, Biddick L, Lightfoot S, Wu XR, Steele V, Kopelovich L, Rao CV.

Cancer Prev Res (Phila). 2014 Jul;7(7):708-16. doi: 10.1158/1940-6207.CAPR-14-0087. Epub 2014 May 2.


Chemopreventive effects of the p53-modulating agents CP-31398 and Prima-1 in tobacco carcinogen-induced lung tumorigenesis in A/J mice.

Rao CV, Patlolla JM, Qian L, Zhang Y, Brewer M, Mohammed A, Desai D, Amin S, Lightfoot S, Kopelovich L.

Neoplasia. 2013 Sep;15(9):1018-27.


β-Escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells.

Patlolla JM, Qian L, Biddick L, Zhang Y, Desai D, Amin S, Lightfoot S, Rao CV.

Cancer Prev Res (Phila). 2013 Oct;6(10):1140-9. doi: 10.1158/1940-6207.CAPR-13-0216. Epub 2013 Aug 20.


Prevention of familial adenomatous polyp development in APC min mice and azoxymethane-induced colon carcinogenesis in F344 Rats by ω-3 fatty acid rich perilla oil.

Rao CV, Patlolla JM, Cooma I, Kawamori T, Steele VE.

Nutr Cancer. 2013;65 Suppl 1:54-60. doi: 10.1080/01635581.2013.785009.


Anti-carcinogenic properties of omeprazole against human colon cancer cells and azoxymethane-induced colonic aberrant crypt foci formation in rats.

Patlolla JM, Zhang Y, Li Q, Steele VE, Rao CV.

Int J Oncol. 2012 Jan;40(1):170-5. doi: 10.3892/ijo.2011.1214. Epub 2011 Sep 28.


Triterpenoids for cancer prevention and treatment: current status and future prospects.

Patlolla JM, Rao CV.

Curr Pharm Biotechnol. 2012 Jan;13(1):147-55. Review.


Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.

Steele VE, Rao CV, Zhang Y, Patlolla J, Boring D, Kopelovich L, Juliana MM, Grubbs CJ, Lubet RA.

Cancer Prev Res (Phila). 2009 Nov;2(11):951-6. doi: 10.1158/1940-6207.CAPR-09-0080.


Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats.

Rao CV, Steele VE, Swamy MV, Patlolla JM, Guruswamy S, Kopelovich L.

Cancer Res. 2009 Oct 15;69(20):8175-82. doi: 10.1158/0008-5472.CAN-09-1377. Epub 2009 Oct 13.


Curcumin protects retinal cells from light-and oxidant stress-induced cell death.

Mandal MN, Patlolla JM, Zheng L, Agbaga MP, Tran JT, Wicker L, Kasus-Jacobi A, Elliott MH, Rao CV, Anderson RE.

Free Radic Biol Med. 2009 Mar 1;46(5):672-9. doi: 10.1016/j.freeradbiomed.2008.12.006. Epub 2008 Dec 24.


Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids.

Swamy MV, Citineni B, Patlolla JM, Mohammed A, Zhang Y, Rao CV.

Nutr Cancer. 2008;60 Suppl 1:81-9. doi: 10.1080/01635580802416703.


Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats.

Rao CV, Joseph S, Gao L, Patlolla JM, Choi CI, Kopelovich L, Steele VE, Rigas B.

Int J Oncol. 2008 Oct;33(4):799-805.


Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice.

Rao CV, Swamy MV, Patlolla JM, Kopelovich L.

Cancer Res. 2008 Sep 15;68(18):7670-5. doi: 10.1158/0008-5472.CAN-08-1610.


Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice.

Swamy MV, Patlolla JM, Steele VE, Kopelovich L, Reddy BS, Rao CV.

Cancer Res. 2006 Jul 15;66(14):7370-7.


Nitric oxide-releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets.

Rao CV, Reddy BS, Steele VE, Wang CX, Liu X, Ouyang N, Patlolla JM, Simi B, Kopelovich L, Rigas B.

Mol Cancer Ther. 2006 Jun;5(6):1530-8.


Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence.

Raju J, Swamy MV, Cooma I, Patlolla JM, Pittman B, Reddy BS, Steele VE, Rao CV.

Int J Cancer. 2005 Feb 20;113(5):798-802.


Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines.

Patlolla JM, Swamy MV, Raju J, Rao CV.

Oncol Rep. 2004 May;11(5):957-63.


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