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Items: 1 to 50 of 159

1.

The roles and controls of GATA factors in blood and cardiac development.

Dobrzycki T, Lalwani M, Telfer C, Monteiro R, Patient R.

IUBMB Life. 2019 Nov 28. doi: 10.1002/iub.2178. [Epub ahead of print]

PMID:
31778014
2.

Direct interaction between the hepatitis B virus core and envelope proteins analyzed in a cellular context.

Pastor F, Herrscher C, Patient R, Eymieux S, Moreau A, Burlaud-Gaillard J, Seigneuret F, de Rocquigny H, Roingeard P, Hourioux C.

Sci Rep. 2019 Nov 7;9(1):16178. doi: 10.1038/s41598-019-52824-z.

3.

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium.

Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R.

Nat Commun. 2019 Aug 8;10(1):3577. doi: 10.1038/s41467-019-11423-2.

4.

Gene Regulatory Networks Governing the Generation and Regeneration of Blood.

Ciau-Uitz A, Patient R.

J Comput Biol. 2019 Jul;26(7):719-725. doi: 10.1089/cmb.2019.0114. Epub 2019 May 29.

PMID:
31140835
5.

Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos.

Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C.

Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y.

6.

New methods for computational decomposition of whole-mount in situ images enable effective curation of a large, highly redundant collection of Xenopus images.

Patrushev I, James-Zorn C, Ciau-Uitz A, Patient R, Gilchrist MJ.

PLoS Comput Biol. 2018 Aug 29;14(8):e1006077. doi: 10.1371/journal.pcbi.1006077. eCollection 2018 Aug.

7.

An optimised pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridisation.

Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R.

Biol Open. 2018 Apr 9;7(4). pii: bio031096. doi: 10.1242/bio.031096.

8.

High-Resolution Magnetic Resonance Imaging of the Regenerating Adult Zebrafish Heart.

Koth J, Maguire ML, McClymont D, Diffley L, Thornton VL, Beech J, Patient RK, Riley PR, Schneider JE.

Sci Rep. 2017 Jun 7;7(1):2917. doi: 10.1038/s41598-017-03050-y.

9.

Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage.

Kirmizitas A, Meiklejohn S, Ciau-Uitz A, Stephenson R, Patient R.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):5814-5821. doi: 10.1073/pnas.1610615114.

10.

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T, Vaidya H, Mead AJ, Atkinson D, Böiers C, Carrelha J, Macaulay IC, Patient R, Geissmann F, Nerlov C, Sandberg R, de Bruijn MFTR, Blackburn CC, Godin I, Jacobsen SEW.

Nat Immunol. 2016 Dec;17(12):1424-1435. doi: 10.1038/ni.3576. Epub 2016 Oct 3.

11.

The embryonic origins and genetic programming of emerging haematopoietic stem cells.

Ciau-Uitz A, Patient R.

FEBS Lett. 2016 Nov;590(22):4002-4015. doi: 10.1002/1873-3468.12363. Epub 2016 Sep 1. Review.

12.

Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells.

Monteiro R, Pinheiro P, Joseph N, Peterkin T, Koth J, Repapi E, Bonkhofer F, Kirmizitas A, Patient R.

Dev Cell. 2016 Aug 22;38(4):358-70. doi: 10.1016/j.devcel.2016.06.024. Epub 2016 Aug 4.

13.

Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved.

Long HK, King HW, Patient RK, Odom DT, Klose RJ.

Nucleic Acids Res. 2016 Aug 19;44(14):6693-706. doi: 10.1093/nar/gkw258. Epub 2016 Apr 15.

14.

Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors.

Short S, Peterkin T, Guille M, Patient R, Sharpe C.

Open Biol. 2015 Aug;5(8). pii: 150063. doi: 10.1098/rsob.150063.

15.

A novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedback.

Gu W, Monteiro R, Zuo J, Simões FC, Martella A, Andrieu-Soler C, Grosveld F, Sauka-Spengler T, Patient R.

PLoS Biol. 2015 Feb 9;13(2):e1002051. doi: 10.1371/journal.pbio.1002051. eCollection 2015 Feb.

16.

FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway.

Pouget C, Peterkin T, Simões FC, Lee Y, Traver D, Patient R.

Nat Commun. 2014 Nov 27;5:5588. doi: 10.1038/ncomms6588.

17.

Developmental hematopoiesis: ontogeny, genetic programming and conservation.

Ciau-Uitz A, Monteiro R, Kirmizitas A, Patient R.

Exp Hematol. 2014 Aug;42(8):669-83. doi: 10.1016/j.exphem.2014.06.001. Epub 2014 Jun 17. Review.

PMID:
24950425
18.

Stochastic specification of primordial germ cells from mesoderm precursors in axolotl embryos.

Chatfield J, O'Reilly MA, Bachvarova RF, Ferjentsik Z, Redwood C, Walmsley M, Patient R, Loose M, Johnson AD.

Development. 2014 Jun;141(12):2429-40. doi: 10.1242/dev.105346.

19.

The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity.

Gorsi B, Liu F, Ma X, Chico TJ, v A, Kramer KL, Bridges E, Monteiro R, Harris AL, Patient R, Stringer SE.

Angiogenesis. 2014 Jan;17(1):77-91. doi: 10.1007/s10456-013-9379-0.

PMID:
23959107
20.

ETS transcription factors in hematopoietic stem cell development.

Ciau-Uitz A, Wang L, Patient R, Liu F.

Blood Cells Mol Dis. 2013 Dec;51(4):248-55. doi: 10.1016/j.bcmd.2013.07.010. Epub 2013 Aug 6. Review.

PMID:
23927967
21.

MiR-142-3p controls the specification of definitive hemangioblasts during ontogeny.

Nimmo R, Ciau-Uitz A, Ruiz-Herguido C, Soneji S, Bigas A, Patient R, Enver T.

Dev Cell. 2013 Aug 12;26(3):237-49. doi: 10.1016/j.devcel.2013.06.023. Epub 2013 Aug 1.

22.

A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.

Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM.

Cancer Cell. 2013 Aug 12;24(2):229-41. doi: 10.1016/j.ccr.2013.06.004. Epub 2013 Jul 18.

23.

Structural basis for LMO2-driven recruitment of the SCL:E47bHLH heterodimer to hematopoietic-specific transcriptional targets.

El Omari K, Hoosdally SJ, Tuladhar K, Karia D, Hall-Ponselé E, Platonova O, Vyas P, Patient R, Porcher C, Mancini EJ.

Cell Rep. 2013 Jul 11;4(1):135-47. doi: 10.1016/j.celrep.2013.06.008. Epub 2013 Jul 3.

24.

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.

Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-Del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11893-8. doi: 10.1073/pnas.1300805110. Epub 2013 Jul 1.

25.

Gene regulatory networks in the genomics era.

Loose M, Patient R, Fang X, Lei H.

Genomics Proteomics Bioinformatics. 2013 Jun;11(3):133-4. doi: 10.1016/j.gpb.2013.05.004. Epub 2013 Jun 3. No abstract available.

26.

VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus.

Ciau-Uitz A, Pinheiro P, Kirmizitas A, Zuo J, Patient R.

Development. 2013 Jun;140(12):2632-42. doi: 10.1242/dev.090829. Epub 2013 May 1.

27.

Fev regulates hematopoietic stem cell development via ERK signaling.

Wang L, Liu T, Xu L, Gao Y, Wei Y, Duan C, Chen GQ, Lin S, Patient R, Zhang B, Hong D, Liu F.

Blood. 2013 Jul 18;122(3):367-75. doi: 10.1182/blood-2012-10-462655. Epub 2013 Apr 16.

PMID:
23591790
28.

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.

Long HK, Sims D, Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R, Ponting CP, Klose RJ.

Elife. 2013 Feb 26;2:e00348. doi: 10.7554/eLife.00348.

29.

Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification.

Leung A, Ciau-Uitz A, Pinheiro P, Monteiro R, Zuo J, Vyas P, Patient R, Porcher C.

Dev Cell. 2013 Jan 28;24(2):144-58. doi: 10.1016/j.devcel.2012.12.004. Epub 2013 Jan 11.

30.

Chimeric hepatitis B virus/hepatitis C virus envelope proteins elicit broadly neutralizing antibodies and constitute a potential bivalent prophylactic vaccine.

Beaumont E, Patient R, Hourioux C, Dimier-Poisson I, Roingeard P.

Hepatology. 2013 Apr;57(4):1303-13. doi: 10.1002/hep.26132. Epub 2013 Mar 14.

31.

The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis.

Bridge G, Monteiro R, Henderson S, Emuss V, Lagos D, Georgopoulou D, Patient R, Boshoff C.

Blood. 2012 Dec 13;120(25):5063-72. doi: 10.1182/blood-2012-04-423004. Epub 2012 Oct 18.

PMID:
23086751
32.

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.

van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F.

Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16.

33.

Hematopoietic stem cell development and regulatory signaling in zebrafish.

Zhang C, Patient R, Liu F.

Biochim Biophys Acta. 2013 Feb;1830(2):2370-4. doi: 10.1016/j.bbagen.2012.06.008. Epub 2012 Jun 15. Review.

PMID:
22705943
34.

Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.

Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ.

Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5.

35.

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.

Luc S, Luis TC, Boukarabila H, Macaulay IC, Buza-Vidas N, Bouriez-Jones T, Lutteropp M, Woll PS, Loughran SJ, Mead AJ, Hultquist A, Brown J, Mizukami T, Matsuoka S, Ferry H, Anderson K, Duarte S, Atkinson D, Soneji S, Domanski A, Farley A, Sanjuan-Pla A, Carella C, Patient R, de Bruijn M, Enver T, Nerlov C, Blackburn C, Godin I, Jacobsen SE.

Nat Immunol. 2012 Feb 19;13(4):412-9. doi: 10.1038/ni.2255.

36.

Bio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNA.

Blackledge NP, Long HK, Zhou JC, Kriaucionis S, Patient R, Klose RJ.

Nucleic Acids Res. 2012 Feb;40(4):e32. doi: 10.1093/nar/gkr1207. Epub 2011 Dec 10.

37.

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos.

Wang L, Zhang P, Wei Y, Gao Y, Patient R, Liu F.

Blood. 2011 Oct 13;118(15):4102-10. doi: 10.1182/blood-2011-05-353235. Epub 2011 Aug 17.

PMID:
21849483
38.

Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators.

Simões FC, Peterkin T, Patient R.

Development. 2011 Aug;138(15):3235-45. doi: 10.1242/dev.059634.

39.

Both innate and adaptive immunity mediate protective immunity against hepatitis C virus infection in chimpanzees.

Barth H, Rybczynska J, Patient R, Choi Y, Sapp RK, Baumert TF, Krawczynski K, Liang TJ.

Hepatology. 2011 Oct;54(4):1135-48. doi: 10.1002/hep.24489. Epub 2011 Aug 11.

40.

The gata1/pu.1 lineage fate paradigm varies between blood populations and is modulated by tif1γ.

Monteiro R, Pouget C, Patient R.

EMBO J. 2011 Mar 16;30(6):1093-103. doi: 10.1038/emboj.2011.34. Epub 2011 Feb 18.

41.

Cardiopoietic factors: extracellular signals for cardiac lineage commitment.

Noseda M, Peterkin T, Simões FC, Patient R, Schneider MD.

Circ Res. 2011 Jan 7;108(1):129-52. doi: 10.1161/CIRCRESAHA.110.223792.

42.

Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex.

El Omari K, Hoosdally SJ, Tuladhar K, Karia D, Vyas P, Patient R, Porcher C, Mancini EJ.

Blood. 2011 Feb 17;117(7):2146-56. doi: 10.1182/blood-2010-07-293357. Epub 2010 Nov 12.

PMID:
21076045
43.

Separating early sensory neuron and blood vessel patterning.

Miller LC, Freter S, Liu F, Taylor JS, Patient R, Begbie J.

Dev Dyn. 2010 Dec;239(12):3297-302. doi: 10.1002/dvdy.22464.

44.

Genetic control of hematopoietic development in Xenopus and zebrafish.

Ciau-Uitz A, Liu F, Patient R.

Int J Dev Biol. 2010;54(6-7):1139-49. doi: 10.1387/ijdb.093055ac. Review.

45.

Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling.

Ciau-Uitz A, Pinheiro P, Gupta R, Enver T, Patient R.

Dev Cell. 2010 Apr 20;18(4):569-78. doi: 10.1016/j.devcel.2010.02.009.

46.

Notch signalling and haematopoietic stem cell formation during embryogenesis.

Gering M, Patient R.

J Cell Physiol. 2010 Jan;222(1):11-6. doi: 10.1002/jcp.21905. Review.

PMID:
19725072
47.

Morphogenesis of hepatitis B virus and its subviral envelope particles.

Patient R, Hourioux C, Roingeard P.

Cell Microbiol. 2009 Nov;11(11):1561-70. doi: 10.1111/j.1462-5822.2009.01363.x. Epub 2009 Aug 5. Review.

48.

Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta.

Wilkinson RN, Pouget C, Gering M, Russell AJ, Davies SG, Kimelman D, Patient R.

Dev Cell. 2009 Jun;16(6):909-16. doi: 10.1016/j.devcel.2009.04.014.

49.

Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: implications for the design of new vaccine strategies.

Patient R, Hourioux C, Vaudin P, Pagès JC, Roingeard P.

N Biotechnol. 2009 Apr;25(4):226-34. doi: 10.1016/j.nbt.2009.01.001. Epub 2009 Jan 21.

50.

Common genetic control of haemangioblast and cardiac development in zebrafish.

Peterkin T, Gibson A, Patient R.

Development. 2009 May;136(9):1465-74. doi: 10.1242/dev.032748. Epub 2009 Mar 18.

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