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Items: 46

1.

Candida albicans biofilm development is governed by cooperative attachment and adhesion maintenance proteins.

McCall AD, Pathirana RU, Prabhakar A, Cullen PJ, Edgerton M.

NPJ Biofilms Microbiomes. 2019 Aug 23;5:21. doi: 10.1038/s41522-019-0094-5. eCollection 2019.

2.

Live attenuated influenza vaccine induces tonsillar follicular T helper cell responses that correlate with antibody induction.

Lartey S, Zhou F, Brokstad KA, Mohn KG, Slettevoll SA, Pathirana RD, Cox RJ.

J Infect Dis. 2019 Jun 27. pii: jiz321. doi: 10.1093/infdis/jiz321. [Epub ahead of print]

PMID:
31250024
3.

Filamentous Non-albicans Candida Species Adhere to Candida albicans and Benefit From Dual Biofilm Growth.

Pathirana RU, McCall AD, Norris HL, Edgerton M.

Front Microbiol. 2019 May 31;10:1188. doi: 10.3389/fmicb.2019.01188. eCollection 2019.

4.

Candida albicans Ras1 Inactivation Increases Resistance to Phagosomal Killing by Human Neutrophils.

Salvatori O, Pathirana RU, Kay JG, Edgerton M.

Infect Immun. 2018 Nov 20;86(12). pii: e00685-18. doi: 10.1128/IAI.00685-18. Print 2018 Dec.

5.

Cold, antioxidant and osmotic pre-treatments maintain the structural integrity of meristematic cells and improve plant regeneration in cryopreserved kiwifruit shoot tips.

Mathew L, McLachlan A, Jibran R, Burritt DJ, Pathirana R.

Protoplasma. 2018 Jul;255(4):1065-1077. doi: 10.1007/s00709-018-1215-3. Epub 2018 Feb 5.

PMID:
29404697
6.

Fluconazole-Resistant Candida auris Is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses.

Pathirana RU, Friedman J, Norris HL, Salvatori O, McCall AD, Kay J, Edgerton M.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01872-17. doi: 10.1128/AAC.01872-17. Print 2018 Feb.

7.

Bacterial membrane vesicles: Biogenesis, immune regulation and pathogenesis.

Pathirana RD, Kaparakis-Liaskos M.

Cell Microbiol. 2016 Nov;18(11):1518-1524. doi: 10.1111/cmi.12658. Epub 2016 Sep 25. Review.

PMID:
27564529
8.

Candida albicans ISW2 Regulates Chlamydospore Suspensor Cell Formation and Virulence In Vivo in a Mouse Model of Disseminated Candidiasis.

Navarathna DH, Pathirana RU, Lionakis MS, Nickerson KW, Roberts DD.

PLoS One. 2016 Oct 11;11(10):e0164449. doi: 10.1371/journal.pone.0164449. eCollection 2016.

9.

Biotin Auxotrophy and Biotin Enhanced Germ Tube Formation in Candida albicans.

Ahmad Hussin N, Pathirana RU, Hasim S, Tati S, Scheib-Owens JA, Nickerson KW.

Microorganisms. 2016 Sep 21;4(3). pii: E37. doi: 10.3390/microorganisms4030037.

10.

Live Attenuated Influenza Vaccine in Children Induces B-Cell Responses in Tonsils.

Mohn KG, Brokstad KA, Pathirana RD, Bredholt G, Jul-Larsen Å, Trieu MC, Lartey SL, Montomoli E, Tøndel C, Aarstad HJ, Cox RJ.

J Infect Dis. 2016 Sep 1;214(5):722-31. doi: 10.1093/infdis/jiw230. Epub 2016 May 30. Erratum in: J Infect Dis. 2016 Oct 3;:.

11.

Humoral, T-cell and B-cell immune responses to seasonal influenza vaccine in solid organ transplant recipients receiving anti-T cell therapies.

Héquet D, Pascual M, Lartey S, Pathirana RD, Bredholt G, Hoschler K, Hullin R, Meylan P, Cox RJ, Manuel O.

Vaccine. 2016 Jun 30;34(31):3576-83. doi: 10.1016/j.vaccine.2016.05.021. Epub 2016 May 21.

PMID:
27219339
12.

Cell death patterns in Arabidopsis cells subjected to four physiological stressors indicate multiple signalling pathways and cell cycle phase specificity.

Pathirana R, West P, Hedderley D, Eason J.

Protoplasma. 2017 Mar;254(2):635-647. doi: 10.1007/s00709-016-0977-8. Epub 2016 May 18.

PMID:
27193098
13.

Matrix M H5N1 Vaccine Induces Cross-H5 Clade Humoral Immune Responses in a Randomized Clinical Trial and Provides Protection from Highly Pathogenic Influenza Challenge in Ferrets.

Cox RJ, Major D, Pedersen G, Pathirana RD, Hoschler K, Guilfoyle K, Roseby S, Bredholt G, Assmus J, Breakwell L, Campitelli L, Sjursen H.

PLoS One. 2015 Jul 6;10(7):e0131652. doi: 10.1371/journal.pone.0131652. eCollection 2015.

14.

Single dose vaccination of the ASO3-adjuvanted A(H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains.

Lartey S, Pathirana RD, Zhou F, Jul-Larsen Å, Montomoli E, Wood J, Cox RJ.

Hum Vaccin Immunother. 2015;11(7):1654-62. doi: 10.1080/21645515.2015.1048939.

15.

Intranasal vaccination with a plant-derived H5 HA vaccine protects mice and ferrets against highly pathogenic avian influenza virus challenge.

Major D, Chichester JA, Pathirana RD, Guilfoyle K, Shoji Y, Guzman CA, Yusibov V, Cox RJ.

Hum Vaccin Immunother. 2015;11(5):1235-43. doi: 10.4161/21645515.2014.988554.

16.

Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children.

Mohn KG, Bredholt G, Brokstad KA, Pathirana RD, Aarstad HJ, Tøndel C, Cox RJ.

J Infect Dis. 2015 May 15;211(10):1541-9. doi: 10.1093/infdis/jiu654. Epub 2014 Nov 25.

17.

Serum IgG titres, but not avidity, correlates with neutralizing antibody response after H5N1 vaccination.

Pedersen GK, Höschler K, Øie Solbak SM, Bredholt G, Pathirana RD, Afsar A, Breakwell L, Nøstbakken JK, Raae AJ, Brokstad KA, Sjursen H, Zambon M, Cox RJ.

Vaccine. 2014 Jul 31;32(35):4550-7. doi: 10.1016/j.vaccine.2014.06.009. Epub 2014 Jun 18.

PMID:
24950357
18.

Novel antiviral activity of l-dideoxy bicyclic nucleoside analogues versus vaccinia and measles viruses in vitro.

McGuigan C, Hinsinger K, Farleigh L, Pathirana RN, Bugert JJ.

J Med Chem. 2013 Feb 14;56(3):1311-22. doi: 10.1021/jm301778x. Epub 2013 Jan 29.

PMID:
23320521
19.

Reply to Sambhara.

Bredholt G, Pedersen GK, Pathirana RD, Akselsen PE, Jane Cox R.

J Infect Dis. 2013 Apr;207(7):1186-8. doi: 10.1093/infdis/jit014. Epub 2013 Jan 10. No abstract available.

PMID:
23307933
20.

A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.

Svindland SC, Pedersen GK, Pathirana RD, Bredholt G, Nøstbakken JK, Jul-Larsen Å, Guzmán CA, Montomoli E, Lapini G, Piccirella S, Jabbal-Gill I, Hinchcliffe M, Cox RJ.

Influenza Other Respir Viruses. 2013 Nov;7(6):1181-93. doi: 10.1111/irv.12056. Epub 2012 Nov 21.

21.

A(H1N1)pdm09 vaccination of health care workers: improved immune responses in low responders following revaccination.

Pathirana RD, Bredholt G, Akselsen PE, Pedersen GK, Cox RJ.

J Infect Dis. 2012 Dec 1;206(11):1660-9. doi: 10.1093/infdis/jis589. Epub 2012 Sep 11.

PMID:
22969149
22.

T-helper 1 cells elicited by H5N1 vaccination predict seroprotection.

Pedersen GK, Madhun AS, Breakwell L, Hoschler K, Sjursen H, Pathirana RD, Goudsmit J, Cox RJ.

J Infect Dis. 2012 Jul 15;206(2):158-66. doi: 10.1093/infdis/jis330. Epub 2012 May 2.

PMID:
22551811
23.

Biofortification of tomato (Solanum lycopersicum) fruit with the anticancer compound methylselenocysteine using a selenocysteine methyltransferase from a selenium hyperaccumulator.

Brummell DA, Watson LM, Pathirana R, Joyce NI, West PJ, Hunter DA, McKenzie MJ.

J Agric Food Chem. 2011 Oct 26;59(20):10987-94. doi: 10.1021/jf202583f. Epub 2011 Sep 26.

PMID:
21942920
24.

The mucosal and systemic immune responses elicited by a chitosan-adjuvanted intranasal influenza H5N1 vaccine.

Svindland SC, Jul-Larsen Å, Pathirana R, Andersen S, Madhun A, Montomoli E, Jabbal-Gill I, Cox RJ.

Influenza Other Respir Viruses. 2012 Mar;6(2):90-100. doi: 10.1111/j.1750-2659.2011.00271.x. Epub 2011 Jul 12.

25.

Haploid and doubled haploid plants from developing male and female gametes of Gentiana triflora.

Pathirana R, Frew T, Hedderley D, Timmerman-Vaughan G, Morgan E.

Plant Cell Rep. 2011 Jun;30(6):1055-65. doi: 10.1007/s00299-011-1012-3. Epub 2011 Feb 4.

PMID:
21293862
26.

Host immune responses to Porphyromonas gingivalis antigens.

Pathirana RD, O'Brien-Simpson NM, Reynolds EC.

Periodontol 2000. 2010 Feb;52(1):218-37. doi: 10.1111/j.1600-0757.2009.00330.x. Review. No abstract available.

PMID:
20017803
27.

Porphyromonas gingivalis RgpA-Kgp proteinase-adhesin complexes penetrate gingival tissue and induce proinflammatory cytokines or apoptosis in a concentration-dependent manner.

O'Brien-Simpson NM, Pathirana RD, Walker GD, Reynolds EC.

Infect Immun. 2009 Mar;77(3):1246-61. doi: 10.1128/IAI.01038-08. Epub 2008 Dec 29.

28.

Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.

McKenzie MJ, Hunter DA, Pathirana R, Watson LM, Joyce NI, Matich AJ, Rowan DD, Brummell DA.

Transgenic Res. 2009 Jun;18(3):407-24. doi: 10.1007/s11248-008-9233-0. Epub 2008 Dec 3.

PMID:
19051051
29.

The role of the RgpA-Kgp proteinase-adhesin complexes in the adherence of Porphyromonas gingivalis to fibroblasts.

Pathirana RD, O'Brien-Simpson NM, Visvanathan K, Hamilton JA, Reynolds EC.

Microbiology. 2008 Oct;154(Pt 10):2904-11. doi: 10.1099/mic.0.2008/019943-0.

PMID:
18832297
30.

Characterization of T cell responses to the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis in BALB/c mice.

Tam V, O'Brien-Simpson NM, Pathirana RD, Frazer LT, Reynolds EC.

J Immunol. 2008 Sep 15;181(6):4150-8.

31.

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.

McGuigan C, Pathirana RN, Migliore M, Adak R, Luoni G, Jones AT, Díez-Torrubia A, Camarasa MJ, Velázquez S, Henson G, Verbeken E, Sienaert R, Naesens L, Snoeck R, Andrei G, Balzarini J.

J Antimicrob Chemother. 2007 Dec;60(6):1316-30. Epub 2007 Oct 22.

PMID:
17956908
32.

Flow cytometric analysis of adherence of Porphyromonas gingivalis to oral epithelial cells.

Pathirana RD, O'Brien-Simpson NM, Visvanathan K, Hamilton JA, Reynolds EC.

Infect Immun. 2007 May;75(5):2484-92. Epub 2007 Mar 5.

33.

Kgp and RgpB, but not RgpA, are important for Porphyromonas gingivalis virulence in the murine periodontitis model.

Pathirana RD, O'Brien-Simpson NM, Brammar GC, Slakeski N, Reynolds EC.

Infect Immun. 2007 Mar;75(3):1436-42. Epub 2007 Jan 12.

34.

Characterization of proteinase-adhesin complexes of Porphyromonas gingivalis.

Pathirana RD, O'Brien-Simpson NM, Veith PD, Riley PF, Reynolds EC.

Microbiology. 2006 Aug;152(Pt 8):2381-94.

PMID:
16849802
35.

An immune response directed to proteinase and adhesin functional epitopes protects against Porphyromonas gingivalis-induced periodontal bone loss.

O'Brien-Simpson NM, Pathirana RD, Paolini RA, Chen YY, Veith PD, Tam V, Ally N, Pike RN, Reynolds EC.

J Immunol. 2005 Sep 15;175(6):3980-9.

36.

Removal of the N-linked glycan structure from the peanut peroxidase prxPNC2: influence on protein stability and activity.

Pathirana R, Watson L, Chen B, Leung S, Voisey C, Murray T, McManus MT.

Phytochemistry. 2005 Aug;66(16):1869-79.

PMID:
16112153
37.
38.

High prevalence of eating epilepsy in Sri Lanka.

Seneviratne U, Seetha T, Pathirana R, Rajapakse P.

Seizure. 2003 Dec;12(8):604-5.

39.

Knowledge, attitude, and practice of epilepsy in rural Sri Lanka.

Seneviratne U, Rajapakse P, Pathirana R, Seetha T.

Seizure. 2002 Jan;11(1):40-3.

40.

Furano pyrimidines as novel potent and selective anti-VZV agents.

McGuigan C, Brancale A, Barucki H, Srinivasan S, Jones G, Pathirana R, Carangio A, Blewett S, Luoni G, Bidet O, Jukes A, Jarvis C, Andrei G, Snoeck R, De Clercq E, Balzarini J.

Antivir Chem Chemother. 2001 Mar;12(2):77-89. Review.

PMID:
11527045
41.

Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency.

McGuigan C, Pathirana RN, Jones G, Andrei G, Snoeck R, De Clercq E, Balzarini J.

Antivir Chem Chemother. 2000 Sep;11(5):343-8.

PMID:
11142633
42.

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

Saboulard D, Naesens L, Cahard D, Salgado A, Pathirana R, Velazquez S, McGuigan C, De Clercq E, Balzarini J.

Mol Pharmacol. 1999 Oct;56(4):693-704.

PMID:
10496951
43.

Synthesis and anti-HIV activity of some novel diaryl phosphate derivatives of AZT.

McGuigan C, Davies M, Pathirana R, Mahmood N, Hay AJ.

Antiviral Res. 1994 May;24(1):69-77.

PMID:
7944314
44.

Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT.

McGuigan C, Pathirana RN, Balzarini J, De Clercq E.

J Med Chem. 1993 Apr 16;36(8):1048-52.

PMID:
8478904
45.

Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT.

McGuigan C, Pathirana RN, Mahmood N, Devine KG, Hay AJ.

Antiviral Res. 1992 Apr;17(4):311-21.

PMID:
1642482
46.

Yeasts of the coconut palm wine of Sri Lanka.

Jayatissa PM, Pathirana RA, Sivayogasunderam K, Jeyaraj EE.

J Sci Food Agric. 1978 Nov;29(11):975-8. No abstract available.

PMID:
750744

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