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Items: 1 to 50 of 131

1.

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.

Maiti A, Myint W, Kanai T, Delviks-Frankenberry K, Sierra Rodriguez C, Pathak VK, Schiffer CA, Matsuo H.

Nat Commun. 2018 Jun 25;9(1):2460. doi: 10.1038/s41467-018-04872-8.

2.

Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins.

Singh I, Yadav AR, Mohanty KK, Katoch K, Sharma P, Pathak VK, Bisht D, Gupta UD, Sengupta U.

Front Immunol. 2018 Apr 3;9:642. doi: 10.3389/fimmu.2018.00642. eCollection 2018.

3.

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.

Ziegler SJ, Liu C, Landau M, Buzovetsky O, Desimmie BA, Zhao Q, Sasaki T, Burdick RC, Pathak VK, Anderson KS, Xiong Y.

PLoS One. 2018 Mar 29;13(3):e0195048. doi: 10.1371/journal.pone.0195048. eCollection 2018.

4.

Rhinoorbitocerebral Mucormycosis with Maggots in a Neglected Diabetic Patient.

Pathak VK, Saxena R, Awasthi S, Gaur S, Singh SK.

Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):156-158. doi: 10.1007/s12070-017-1171-9. Epub 2017 Jul 21.

PMID:
29456961
5.

Intricate Estimation and Assessment of Surface Conditioning of Posts to improve Interfacial Adhesion in Post-core Restorations: An in vitro Study.

Gupta P, Sharma A, Pathak VK, Mankeliya S, Bhardwaj S, Dhanare P.

J Contemp Dent Pract. 2017 Dec 1;18(12):1177-1180.

PMID:
29208794
6.

The roles of five conserved lentiviral RNA structures in HIV-1 replication.

Liu Y, Chen J, Nikolaitchik OA, Desimmie BA, Busan S, Pathak VK, Weeks KM, Hu WS.

Virology. 2018 Jan 15;514:1-8. doi: 10.1016/j.virol.2017.10.020. Epub 2017 Nov 9.

PMID:
29128752
7.

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.

Burdick RC, Delviks-Frankenberry KA, Chen J, Janaka SK, Sastri J, Hu WS, Pathak VK.

PLoS Pathog. 2017 Aug 21;13(8):e1006570. doi: 10.1371/journal.ppat.1006570. eCollection 2017 Aug.

8.

HIV-1 Sequence Necessary and Sufficient to Package Non-viral RNAs into HIV-1 Particles.

Liu Y, Nikolaitchik OA, Rahman SA, Chen J, Pathak VK, Hu WS.

J Mol Biol. 2017 Aug 4;429(16):2542-2555. doi: 10.1016/j.jmb.2017.06.018. Epub 2017 Jun 30.

PMID:
28673553
9.

Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly.

Dilley KA, Nikolaitchik OA, Galli A, Burdick RC, Levine L, Li K, Rein A, Pathak VK, Hu WS.

J Virol. 2017 Jul 27;91(16). pii: e02319-16. doi: 10.1128/JVI.02319-16. Print 2017 Aug 15.

10.

Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function.

Desimmie BA, Smith JL, Matsuo H, Hu WS, Pathak VK.

Retrovirology. 2017 Mar 17;14(1):19. doi: 10.1186/s12977-017-0346-5.

11.

APOBEC3 proteins can copackage and comutate HIV-1 genomes.

Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK.

Nucleic Acids Res. 2016 Sep 19;44(16):7848-65. doi: 10.1093/nar/gkw653. Epub 2016 Jul 20.

12.

Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.

Delviks-Frankenberry KA, Nikolaitchik OA, Burdick RC, Gorelick RJ, Keele BF, Hu WS, Pathak VK.

PLoS Pathog. 2016 May 17;12(5):e1005646. doi: 10.1371/journal.ppat.1005646. eCollection 2016 May.

13.

HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein.

Chen J, Rahman SA, Nikolaitchik OA, Grunwald D, Sardo L, Burdick RC, Plisov S, Liang E, Tai S, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E201-8. doi: 10.1073/pnas.1518572113. Epub 2015 Dec 28.

14.

A Case Report of Post Rabipur (Purified Chick Embryo Rabies Vaccine) Acute Disseminated Encephalomyelitis.

Kumar R, Singh AK, Pradhan RN, Pathak VK.

J Assoc Physicians India. 2015 Jan;63(1):56-8.

PMID:
26591130
15.

Efficacy of Epley's Maneuver in Treating BPPV Patients: A Prospective Observational Study.

Gaur S, Awasthi SK, Bhadouriya SK, Saxena R, Pathak VK, Bisht M.

Int J Otolaryngol. 2015;2015:487160. doi: 10.1155/2015/487160. Epub 2015 Oct 1.

16.

Dynamics of HIV-1 RNA Near the Plasma Membrane during Virus Assembly.

Sardo L, Hatch SC, Chen J, Nikolaitchik O, Burdick RC, Chen D, Westlake CJ, Lockett S, Pathak VK, Hu WS.

J Virol. 2015 Nov;89(21):10832-40. doi: 10.1128/JVI.01146-15. Epub 2015 Aug 19.

17.

High recombination potential of subtype A HIV-1.

Nikolaitchik O, Keele B, Gorelick R, Alvord WG, Mazurov D, Pathak VK, Hu WS.

Virology. 2015 Oct;484:334-40. doi: 10.1016/j.virol.2015.06.025. Epub 2015 Jul 9.

18.

Selection of peptide mimics of HIV-1 epitope recognized by neutralizing antibody VRC01.

Chikaev AN, Bakulina AY, Burdick RC, Karpenko LI, Pathak VK, Ilyichev AA.

PLoS One. 2015 Mar 18;10(3):e0120847. doi: 10.1371/journal.pone.0120847. eCollection 2015.

19.

Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein.

Chen J, Grunwald D, Sardo L, Galli A, Plisov S, Nikolaitchik OA, Chen D, Lockett S, Larson DR, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5205-13. doi: 10.1073/pnas.1413169111. Epub 2014 Nov 17.

20.

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

Sato K, Takeuchi JS, Misawa N, Izumi T, Kobayashi T, Kimura Y, Iwami S, Takaori-Kondo A, Hu WS, Aihara K, Ito M, An DS, Pathak VK, Koyanagi Y.

PLoS Pathog. 2014 Oct 16;10(10):e1004453. doi: 10.1371/journal.ppat.1004453. eCollection 2014 Oct.

21.

HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants.

Smith JL, Izumi T, Borbet TC, Hagedorn AN, Pathak VK.

J Virol. 2014 Sep 1;88(17):9893-908. doi: 10.1128/JVI.01318-14. Epub 2014 Jun 18.

22.

Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.

Burdick RC, Hu WS, Pathak VK.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4780-9. doi: 10.1073/pnas.1315996110. Epub 2013 Nov 18.

23.

Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.

Desimmie BA, Delviks-Frankenberrry KA, Burdick RC, Qi D, Izumi T, Pathak VK.

J Mol Biol. 2014 Mar 20;426(6):1220-45. doi: 10.1016/j.jmb.2013.10.033. Epub 2013 Nov 2. Review.

24.

Gag-dependent enrichment of HIV-1 RNA near the uropod membrane of polarized T cells.

Hatch SC, Sardo L, Chen J, Burdick R, Gorelick R, Fivash MJ Jr, Pathak VK, Hu WS.

J Virol. 2013 Nov;87(21):11912-5. doi: 10.1128/JVI.01680-13. Epub 2013 Aug 21.

25.

Generation of multiple replication-competent retroviruses through recombination between PreXMRV-1 and PreXMRV-2.

Delviks-Frankenberry K, Paprotka T, Cingöz O, Wildt S, Hu WS, Coffin JM, Pathak VK.

J Virol. 2013 Nov;87(21):11525-37. doi: 10.1128/JVI.01787-13. Epub 2013 Aug 21.

26.

Mov10 and APOBEC3G localization to processing bodies is not required for virion incorporation and antiviral activity.

Izumi T, Burdick R, Shigemi M, Plisov S, Hu WS, Pathak VK.

J Virol. 2013 Oct;87(20):11047-62. doi: 10.1128/JVI.02070-13. Epub 2013 Aug 7.

27.

Dimeric RNA recognition regulates HIV-1 genome packaging.

Nikolaitchik OA, Dilley KA, Fu W, Gorelick RJ, Tai SH, Soheilian F, Ptak RG, Nagashima K, Pathak VK, Hu WS.

PLoS Pathog. 2013 Mar;9(3):e1003249. doi: 10.1371/journal.ppat.1003249. Epub 2013 Mar 21.

28.

Xenotropic MLV envelope proteins induce tumor cells to secrete factors that promote the formation of immature blood vessels.

Murgai M, Thomas J, Cherepanova O, Delviks-Frankenberry K, Deeble P, Pathak VK, Rekosh D, Owens G.

Retrovirology. 2013 Mar 27;10:34. doi: 10.1186/1742-4690-10-34.

29.

APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.

Chaipan C, Smith JL, Hu WS, Pathak VK.

J Virol. 2013 Jan;87(1):444-53. doi: 10.1128/JVI.00676-12. Epub 2012 Oct 24.

30.

Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance.

Delviks-Frankenberry KA, Lengruber RB, Santos AF, Silveira JM, Soares MA, Kearney MF, Maldarelli F, Pathak VK.

Virology. 2013 Jan 20;435(2):433-41. doi: 10.1016/j.virol.2012.09.021. Epub 2012 Oct 13.

31.

Recombinant origin, contamination, and de-discovery of XMRV.

Delviks-Frankenberry K, Cingöz O, Coffin JM, Pathak VK.

Curr Opin Virol. 2012 Aug;2(4):499-507. doi: 10.1016/j.coviro.2012.06.009. Epub 2012 Jul 19. Review.

32.

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients.

Delviks-Frankenberry KA, Chaipan C, Bagni R, Wyvill K, Yarchoan R, Pathak VK.

Adv Virol. 2011;2011:797820. doi: 10.1155/2011/797820. Epub 2011 Sep 8.

33.

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples.

Kearney MF, Lee K, Bagni RK, Wiegand A, Spindler J, Maldarelli F, Pinto PA, Linehan WM, Vocke CD, Delviks-Frankenberry KA, Devere White RW, Del Prete GQ, Mellors JW, Lifson JD, Kewalramani VN, Pathak VK, Coffin JM, Le Grice SF.

Adv Virol. 2011;2011:272193. doi: 10.1155/2011/272193. Epub 2011 Nov 17.

34.

Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.

Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW Jr, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD.

J Virol. 2012 Mar;86(6):3152-66. doi: 10.1128/JVI.06886-11. Epub 2012 Jan 11.

35.

Characterization, mapping, and distribution of the two XMRV parental proviruses.

Cingöz O, Paprotka T, Delviks-Frankenberry KA, Wildt S, Hu WS, Pathak VK, Coffin JM.

J Virol. 2012 Jan;86(1):328-38. doi: 10.1128/JVI.06022-11. Epub 2011 Oct 26.

36.

Mechanisms and factors that influence high frequency retroviral recombination.

Delviks-Frankenberry K, Galli A, Nikolaitchik O, Mens H, Pathak VK, Hu WS.

Viruses. 2011 Sep;3(9):1650-80. doi: 10.3390/v3091650. Epub 2011 Sep 9. Review.

37.

Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.

Ndongwe TP, Adedeji AO, Michailidis E, Ong YT, Hachiya A, Marchand B, Ryan EM, Rai DK, Kirby KA, Whatley AS, Burke DH, Johnson M, Ding S, Zheng YM, Liu SL, Kodama E, Delviks-Frankenberry KA, Pathak VK, Mitsuya H, Parniak MA, Singh K, Sarafianos SG.

Nucleic Acids Res. 2012 Jan;40(1):345-59. doi: 10.1093/nar/gkr694. Epub 2011 Sep 8.

38.

The role of amino-terminal sequences in cellular localization and antiviral activity of APOBEC3B.

Pak V, Heidecker G, Pathak VK, Derse D.

J Virol. 2011 Sep;85(17):8538-47. doi: 10.1128/JVI.02645-10. Epub 2011 Jun 29.

39.

Recombinant origin of the retrovirus XMRV.

Paprotka T, Delviks-Frankenberry KA, Cingöz O, Martinez A, Kung HJ, Tepper CG, Hu WS, Fivash MJ Jr, Coffin JM, Pathak VK.

Science. 2011 Jul 1;333(6038):97-101. doi: 10.1126/science.1205292. Epub 2011 May 31.

40.

Mechanisms of human immunodeficiency virus type 2 RNA packaging: efficient trans packaging and selection of RNA copackaging partners.

Ni N, Nikolaitchik OA, Dilley KA, Chen J, Galli A, Fu W, Prasad VV, Ptak RG, Pathak VK, Hu WS.

J Virol. 2011 Aug;85(15):7603-12. doi: 10.1128/JVI.00562-11. Epub 2011 May 25.

41.

Phenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations.

Lengruber RB, Delviks-Frankenberry KA, Nikolenko GN, Baumann J, Santos AF, Pathak VK, Soares MA.

J Antimicrob Chemother. 2011 Apr;66(4):702-8. doi: 10.1093/jac/dkr005. Epub 2011 Jan 26.

42.

Severe restriction of xenotropic murine leukemia virus-related virus replication and spread in cultured human peripheral blood mononuclear cells.

Chaipan C, Dilley KA, Paprotka T, Delviks-Frankenberry KA, Venkatachari NJ, Hu WS, Pathak VK.

J Virol. 2011 May;85(10):4888-97. doi: 10.1128/JVI.00046-11. Epub 2011 Feb 16.

43.

Multiple barriers to recombination between divergent HIV-1 variants revealed by a dual-marker recombination assay.

Nikolaitchik OA, Galli A, Moore MD, Pathak VK, Hu WS.

J Mol Biol. 2011 Apr 8;407(4):521-31. doi: 10.1016/j.jmb.2011.01.052. Epub 2011 Feb 3.

44.

The "Connection" Between HIV Drug Resistance and RNase H.

Delviks-Frankenberry KA, Nikolenko GN, Pathak VK.

Viruses. 2010 Jul 1;2(7):1476-1503.

45.
46.

P body-associated protein Mov10 inhibits HIV-1 replication at multiple stages.

Burdick R, Smith JL, Chaipan C, Friew Y, Chen J, Venkatachari NJ, Delviks-Frankenberry KA, Hu WS, Pathak VK.

J Virol. 2010 Oct;84(19):10241-53. doi: 10.1128/JVI.00585-10. Epub 2010 Jul 28.

47.

Patterns of Human Immunodeficiency Virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants during replication.

Galli A, Kearney M, Nikolaitchik OA, Yu S, Chin MP, Maldarelli F, Coffin JM, Pathak VK, Hu WS.

J Virol. 2010 Aug;84(15):7651-61. doi: 10.1128/JVI.00276-10. Epub 2010 May 26.

48.

Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.

Paprotka T, Venkatachari NJ, Chaipan C, Burdick R, Delviks-Frankenberry KA, Hu WS, Pathak VK.

J Virol. 2010 Jun;84(11):5719-29. doi: 10.1128/JVI.00134-10. Epub 2010 Mar 24.

49.

A novel molecular mechanism of dual resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors.

Nikolenko GN, Delviks-Frankenberry KA, Pathak VK.

J Virol. 2010 May;84(10):5238-49. doi: 10.1128/JVI.01545-09. Epub 2010 Mar 10.

50.

APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms.

Mbisa JL, Bu W, Pathak VK.

J Virol. 2010 May;84(10):5250-9. doi: 10.1128/JVI.02358-09. Epub 2010 Mar 10.

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