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Visualizing the translation and packaging of HIV-1 full-length RNA.

Chen J, Liu Y, Wu B, Nikolaitchik OA, Mohan PR, Chen J, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6145-6155. doi: 10.1073/pnas.1917590117. Epub 2020 Mar 4.


HIV-1 uncoats in the nucleus near sites of integration.

Burdick RC, Li C, Munshi M, Rawson JMO, Nagashima K, Hu WS, Pathak VK.

Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5486-5493. doi: 10.1073/pnas.1920631117. Epub 2020 Feb 24.


Vaccination coverage and vaccine hesitancy among vulnerable population of India.

Priya P K, Pathak VK, Giri AK.

Hum Vaccin Immunother. 2020 Feb 4:1-6. doi: 10.1080/21645515.2019.1708164. [Epub ahead of print]


Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.

Hu Y, Desimmie BA, Nguyen HC, Ziegler SJ, Cheng TC, Chen J, Wang J, Wang H, Zhang K, Pathak VK, Xiong Y.

Nat Struct Mol Biol. 2019 Dec;26(12):1176-1183. doi: 10.1038/s41594-019-0343-6. Epub 2019 Dec 2.


Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G.

Delviks-Frankenberry KA, Ackerman D, Timberlake ND, Hamscher M, Nikolaitchik OA, Hu WS, Torbett BE, Pathak VK.

Mol Ther Nucleic Acids. 2019 Dec 6;18:1023-1038. doi: 10.1016/j.omtn.2019.10.024. Epub 2019 Oct 31.


A notorious vector-borne disease: Dengue fever, its evolution as public health threat.

Pathak VK, Mohan M.

J Family Med Prim Care. 2019 Oct 31;8(10):3125-3129. doi: 10.4103/jfmpc.jfmpc_716_19. eCollection 2019 Oct. Review.


Authentication Analysis of MT-4 Cells Distributed by the National Institutes of Health AIDS Reagent Program.

Fernandez MV, Delviks-Frankenberry KA, Scheiblin DA, Happel C, Pathak VK, Freed EO.

J Virol. 2019 Nov 26;93(24). pii: e01390-19. doi: 10.1128/JVI.01390-19. Print 2019 Dec 15.


Correction: Health behaviors, outcomes and their relationships among young men aged 18-24 years in a rural area of north India: A cross-sectional study.

Malhotra S, Kant S, Ahamed F, Rath R, Kaladivani M, Gupta SK, Ramadass S, Pathak VK, Jaiswal A, Parthasarathy R, Acharya BP, Dwarakanathan V.

PLoS One. 2019 Aug 15;14(8):e0221493. doi: 10.1371/journal.pone.0221493. eCollection 2019.


Health behaviors, outcomes and their relationships among young men aged 18-24 years in a rural area of north India: A cross-sectional study.

Malhotra S, Kant S, Ahamed F, Rath R, Kalaivani M, Gupta SK, Ramadass S, Pathak VK, Jaiswal A, Parthasarath R, Acharya BP, Dwarakanathan V.

PLoS One. 2019 Jul 26;14(7):e0220285. doi: 10.1371/journal.pone.0220285. eCollection 2019. Erratum in: PLoS One. 2019 Aug 15;14(8):e0221493.


Utility of multiplex PCR for early diagnosis and household contact surveillance for leprosy.

Pathak VK, Singh I, Turankar RP, Lavania M, Ahuja M, Singh V, Sengupta U.

Diagn Microbiol Infect Dis. 2019 Nov;95(3):114855. doi: 10.1016/j.diagmicrobio.2019.06.007. Epub 2019 Jun 20.


VDR polymorphism, gene expression and vitamin D levels in leprosy patients from North Indian population.

Singh I, Lavania M, Pathak VK, Ahuja M, Turankar RP, Singh V, Sengupta U.

PLoS Negl Trop Dis. 2018 Nov 27;12(11):e0006823. doi: 10.1371/journal.pntd.0006823. eCollection 2018 Nov.


Association of non-tuberculous mycobacteria with Mycobacterium leprae in environment of leprosy endemic regions in India.

Turankar RP, Singh V, Gupta H, Pathak VK, Ahuja M, Singh I, Lavania M, Dinda AK, Sengupta U.

Infect Genet Evol. 2019 Aug;72:191-198. doi: 10.1016/j.meegid.2018.11.010. Epub 2018 Nov 13.


Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity.

Rawson JMO, Nikolaitchik OA, Keele BF, Pathak VK, Hu WS.

Nucleic Acids Res. 2018 Nov 16;46(20):10535-10545. doi: 10.1093/nar/gky910.


Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.

Maiti A, Myint W, Kanai T, Delviks-Frankenberry K, Sierra Rodriguez C, Pathak VK, Schiffer CA, Matsuo H.

Nat Commun. 2018 Jun 25;9(1):2460. doi: 10.1038/s41467-018-04872-8.


Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins.

Singh I, Yadav AR, Mohanty KK, Katoch K, Sharma P, Pathak VK, Bisht D, Gupta UD, Sengupta U.

Front Immunol. 2018 Apr 3;9:642. doi: 10.3389/fimmu.2018.00642. eCollection 2018.


Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.

Ziegler SJ, Liu C, Landau M, Buzovetsky O, Desimmie BA, Zhao Q, Sasaki T, Burdick RC, Pathak VK, Anderson KS, Xiong Y.

PLoS One. 2018 Mar 29;13(3):e0195048. doi: 10.1371/journal.pone.0195048. eCollection 2018.


Rhinoorbitocerebral Mucormycosis with Maggots in a Neglected Diabetic Patient.

Pathak VK, Saxena R, Awasthi S, Gaur S, Singh SK.

Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):156-158. doi: 10.1007/s12070-017-1171-9. Epub 2017 Jul 21.


Intricate Estimation and Assessment of Surface Conditioning of Posts to improve Interfacial Adhesion in Post-core Restorations: An in vitro Study.

Gupta P, Sharma A, Pathak VK, Mankeliya S, Bhardwaj S, Dhanare P.

J Contemp Dent Pract. 2017 Dec 1;18(12):1177-1180.


The roles of five conserved lentiviral RNA structures in HIV-1 replication.

Liu Y, Chen J, Nikolaitchik OA, Desimmie BA, Busan S, Pathak VK, Weeks KM, Hu WS.

Virology. 2018 Jan 15;514:1-8. doi: 10.1016/j.virol.2017.10.020. Epub 2017 Nov 9.


Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.

Burdick RC, Delviks-Frankenberry KA, Chen J, Janaka SK, Sastri J, Hu WS, Pathak VK.

PLoS Pathog. 2017 Aug 21;13(8):e1006570. doi: 10.1371/journal.ppat.1006570. eCollection 2017 Aug.


HIV-1 Sequence Necessary and Sufficient to Package Non-viral RNAs into HIV-1 Particles.

Liu Y, Nikolaitchik OA, Rahman SA, Chen J, Pathak VK, Hu WS.

J Mol Biol. 2017 Aug 4;429(16):2542-2555. doi: 10.1016/j.jmb.2017.06.018. Epub 2017 Jun 30.


Interactions between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly.

Dilley KA, Nikolaitchik OA, Galli A, Burdick RC, Levine L, Li K, Rein A, Pathak VK, Hu WS.

J Virol. 2017 Jul 27;91(16). pii: e02319-16. doi: 10.1128/JVI.02319-16. Print 2017 Aug 15.


Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function.

Desimmie BA, Smith JL, Matsuo H, Hu WS, Pathak VK.

Retrovirology. 2017 Mar 17;14(1):19. doi: 10.1186/s12977-017-0346-5.


APOBEC3 proteins can copackage and comutate HIV-1 genomes.

Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK.

Nucleic Acids Res. 2016 Sep 19;44(16):7848-65. doi: 10.1093/nar/gkw653. Epub 2016 Jul 20.


Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.

Delviks-Frankenberry KA, Nikolaitchik OA, Burdick RC, Gorelick RJ, Keele BF, Hu WS, Pathak VK.

PLoS Pathog. 2016 May 17;12(5):e1005646. doi: 10.1371/journal.ppat.1005646. eCollection 2016 May.


HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein.

Chen J, Rahman SA, Nikolaitchik OA, Grunwald D, Sardo L, Burdick RC, Plisov S, Liang E, Tai S, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E201-8. doi: 10.1073/pnas.1518572113. Epub 2015 Dec 28.


A Case Report of Post Rabipur (Purified Chick Embryo Rabies Vaccine) Acute Disseminated Encephalomyelitis.

Kumar R, Singh AK, Pradhan RN, Pathak VK.

J Assoc Physicians India. 2015 Jan;63(1):56-8.


Efficacy of Epley's Maneuver in Treating BPPV Patients: A Prospective Observational Study.

Gaur S, Awasthi SK, Bhadouriya SK, Saxena R, Pathak VK, Bisht M.

Int J Otolaryngol. 2015;2015:487160. doi: 10.1155/2015/487160. Epub 2015 Oct 1.


Dynamics of HIV-1 RNA Near the Plasma Membrane during Virus Assembly.

Sardo L, Hatch SC, Chen J, Nikolaitchik O, Burdick RC, Chen D, Westlake CJ, Lockett S, Pathak VK, Hu WS.

J Virol. 2015 Nov;89(21):10832-40. doi: 10.1128/JVI.01146-15. Epub 2015 Aug 19.


High recombination potential of subtype A HIV-1.

Nikolaitchik O, Keele B, Gorelick R, Alvord WG, Mazurov D, Pathak VK, Hu WS.

Virology. 2015 Oct;484:334-40. doi: 10.1016/j.virol.2015.06.025. Epub 2015 Jul 9.


Selection of peptide mimics of HIV-1 epitope recognized by neutralizing antibody VRC01.

Chikaev AN, Bakulina AY, Burdick RC, Karpenko LI, Pathak VK, Ilyichev AA.

PLoS One. 2015 Mar 18;10(3):e0120847. doi: 10.1371/journal.pone.0120847. eCollection 2015.


Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein.

Chen J, Grunwald D, Sardo L, Galli A, Plisov S, Nikolaitchik OA, Chen D, Lockett S, Larson DR, Pathak VK, Hu WS.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5205-13. doi: 10.1073/pnas.1413169111. Epub 2014 Nov 17.


APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

Sato K, Takeuchi JS, Misawa N, Izumi T, Kobayashi T, Kimura Y, Iwami S, Takaori-Kondo A, Hu WS, Aihara K, Ito M, An DS, Pathak VK, Koyanagi Y.

PLoS Pathog. 2014 Oct 16;10(10):e1004453. doi: 10.1371/journal.ppat.1004453. eCollection 2014 Oct.


HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants.

Smith JL, Izumi T, Borbet TC, Hagedorn AN, Pathak VK.

J Virol. 2014 Sep 1;88(17):9893-908. doi: 10.1128/JVI.01318-14. Epub 2014 Jun 18.


Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.

Burdick RC, Hu WS, Pathak VK.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4780-9. doi: 10.1073/pnas.1315996110. Epub 2013 Nov 18.


Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.

Desimmie BA, Delviks-Frankenberrry KA, Burdick RC, Qi D, Izumi T, Pathak VK.

J Mol Biol. 2014 Mar 20;426(6):1220-45. doi: 10.1016/j.jmb.2013.10.033. Epub 2013 Nov 2. Review.


Gag-dependent enrichment of HIV-1 RNA near the uropod membrane of polarized T cells.

Hatch SC, Sardo L, Chen J, Burdick R, Gorelick R, Fivash MJ Jr, Pathak VK, Hu WS.

J Virol. 2013 Nov;87(21):11912-5. doi: 10.1128/JVI.01680-13. Epub 2013 Aug 21.


Generation of multiple replication-competent retroviruses through recombination between PreXMRV-1 and PreXMRV-2.

Delviks-Frankenberry K, Paprotka T, Cingöz O, Wildt S, Hu WS, Coffin JM, Pathak VK.

J Virol. 2013 Nov;87(21):11525-37. doi: 10.1128/JVI.01787-13. Epub 2013 Aug 21.


Mov10 and APOBEC3G localization to processing bodies is not required for virion incorporation and antiviral activity.

Izumi T, Burdick R, Shigemi M, Plisov S, Hu WS, Pathak VK.

J Virol. 2013 Oct;87(20):11047-62. doi: 10.1128/JVI.02070-13. Epub 2013 Aug 7.


Dimeric RNA recognition regulates HIV-1 genome packaging.

Nikolaitchik OA, Dilley KA, Fu W, Gorelick RJ, Tai SH, Soheilian F, Ptak RG, Nagashima K, Pathak VK, Hu WS.

PLoS Pathog. 2013 Mar;9(3):e1003249. doi: 10.1371/journal.ppat.1003249. Epub 2013 Mar 21.


Xenotropic MLV envelope proteins induce tumor cells to secrete factors that promote the formation of immature blood vessels.

Murgai M, Thomas J, Cherepanova O, Delviks-Frankenberry K, Deeble P, Pathak VK, Rekosh D, Owens G.

Retrovirology. 2013 Mar 27;10:34. doi: 10.1186/1742-4690-10-34.


APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.

Chaipan C, Smith JL, Hu WS, Pathak VK.

J Virol. 2013 Jan;87(1):444-53. doi: 10.1128/JVI.00676-12. Epub 2012 Oct 24.


Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance.

Delviks-Frankenberry KA, Lengruber RB, Santos AF, Silveira JM, Soares MA, Kearney MF, Maldarelli F, Pathak VK.

Virology. 2013 Jan 20;435(2):433-41. doi: 10.1016/j.virol.2012.09.021. Epub 2012 Oct 13.


Recombinant origin, contamination, and de-discovery of XMRV.

Delviks-Frankenberry K, Cingöz O, Coffin JM, Pathak VK.

Curr Opin Virol. 2012 Aug;2(4):499-507. doi: 10.1016/j.coviro.2012.06.009. Epub 2012 Jul 19. Review.


Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients.

Delviks-Frankenberry KA, Chaipan C, Bagni R, Wyvill K, Yarchoan R, Pathak VK.

Adv Virol. 2011;2011:797820. doi: 10.1155/2011/797820. Epub 2011 Sep 8.


Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples.

Kearney MF, Lee K, Bagni RK, Wiegand A, Spindler J, Maldarelli F, Pinto PA, Linehan WM, Vocke CD, Delviks-Frankenberry KA, Devere White RW, Del Prete GQ, Mellors JW, Lifson JD, Kewalramani VN, Pathak VK, Coffin JM, Le Grice SF.

Adv Virol. 2011;2011:272193. doi: 10.1155/2011/272193. Epub 2011 Nov 17.


Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.

Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW Jr, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD.

J Virol. 2012 Mar;86(6):3152-66. doi: 10.1128/JVI.06886-11. Epub 2012 Jan 11.


Characterization, mapping, and distribution of the two XMRV parental proviruses.

Cingöz O, Paprotka T, Delviks-Frankenberry KA, Wildt S, Hu WS, Pathak VK, Coffin JM.

J Virol. 2012 Jan;86(1):328-38. doi: 10.1128/JVI.06022-11. Epub 2011 Oct 26.


Mechanisms and factors that influence high frequency retroviral recombination.

Delviks-Frankenberry K, Galli A, Nikolaitchik O, Mens H, Pathak VK, Hu WS.

Viruses. 2011 Sep;3(9):1650-80. doi: 10.3390/v3091650. Epub 2011 Sep 9. Review.


Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.

Ndongwe TP, Adedeji AO, Michailidis E, Ong YT, Hachiya A, Marchand B, Ryan EM, Rai DK, Kirby KA, Whatley AS, Burke DH, Johnson M, Ding S, Zheng YM, Liu SL, Kodama E, Delviks-Frankenberry KA, Pathak VK, Mitsuya H, Parniak MA, Singh K, Sarafianos SG.

Nucleic Acids Res. 2012 Jan;40(1):345-59. doi: 10.1093/nar/gkr694. Epub 2011 Sep 8.

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