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Items: 21

1.

The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis.

Harwood MD, Zhang M, Pathak SM, Neuhoff S.

Drug Metab Dispos. 2019 Aug;47(8):854-864. doi: 10.1124/dmd.119.086959. Epub 2019 May 10.

PMID:
31076413
2.

Biopharmaceutic IVIVE-Mechanistic Modeling of Single- and Two-Phase In Vitro Experiments to Obtain Drug-Specific Parameters for Incorporation Into PBPK Models.

Pathak SM, Schaefer KJ, Jamei M, Turner DB.

J Pharm Sci. 2019 Apr;108(4):1604-1618. doi: 10.1016/j.xphs.2018.11.034. Epub 2018 Nov 23.

3.

In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.

Hens B, Pathak SM, Mitra A, Patel N, Liu B, Patel S, Jamei M, Brouwers J, Augustijns P, Turner DB.

Mol Pharm. 2017 Dec 4;14(12):4321-4333. doi: 10.1021/acs.molpharmaceut.7b00396. Epub 2017 Sep 5.

PMID:
28817288
4.

Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective Using Ketoconazole as a Model Drug.

Pathak SM, Ruff A, Kostewicz ES, Patel N, Turner DB, Jamei M.

Mol Pharm. 2017 Dec 4;14(12):4305-4320. doi: 10.1021/acs.molpharmaceut.7b00406. Epub 2017 Aug 25.

5.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results.

Margolskee A, Darwich AS, Pepin X, Aarons L, Galetin A, Rostami-Hodjegan A, Carlert S, Hammarberg M, Hilgendorf C, Johansson P, Karlsson E, Murphy D, Tannergren C, Thörn H, Yasin M, Mazuir F, Nicolas O, Ramusovic S, Xu C, Pathak SM, Korjamo T, Laru J, Malkki J, Pappinen S, Tuunainen J, Dressman J, Hansmann S, Kostewicz E, He H, Heimbach T, Wu F, Hoft C, Laplanche L, Pang Y, Bolger MB, Huehn E, Lukacova V, Mullin JM, Szeto KX, Costales C, Lin J, McAllister M, Modi S, Rotter C, Varma M, Wong M, Mitra A, Bevernage J, Biewenga J, Van Peer A, Lloyd R, Shardlow C, Langguth P, Mishenzon I, Nguyen MA, Brown J, Lennernäs H, Abrahamsson B.

Eur J Pharm Sci. 2017 Jan 1;96:610-625. doi: 10.1016/j.ejps.2016.10.036. Epub 2016 Nov 2.

PMID:
27816631
6.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes.

Darwich AS, Margolskee A, Pepin X, Aarons L, Galetin A, Rostami-Hodjegan A, Carlert S, Hammarberg M, Hilgendorf C, Johansson P, Karlsson E, Murphy D, Tannergren C, Thörn H, Yasin M, Mazuir F, Nicolas O, Ramusovic S, Xu C, Pathak SM, Korjamo T, Laru J, Malkki J, Pappinen S, Tuunainen J, Dressman J, Hansmann S, Kostewicz E, He H, Heimbach T, Wu F, Hoft C, Pang Y, Bolger MB, Huehn E, Lukacova V, Mullin JM, Szeto KX, Costales C, Lin J, McAllister M, Modi S, Rotter C, Varma M, Wong M, Mitra A, Bevernage J, Biewenga J, Van Peer A, Lloyd R, Shardlow C, Langguth P, Mishenzon I, Nguyen MA, Brown J, Lennernäs H, Abrahamsson B.

Eur J Pharm Sci. 2017 Jan 1;96:626-642. doi: 10.1016/j.ejps.2016.09.037. Epub 2016 Sep 28.

PMID:
27693299
7.

IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds.

Margolskee A, Darwich AS, Pepin X, Pathak SM, Bolger MB, Aarons L, Rostami-Hodjegan A, Angstenberger J, Graf F, Laplanche L, Müller T, Carlert S, Daga P, Murphy D, Tannergren C, Yasin M, Greschat-Schade S, Mück W, Muenster U, van der Mey D, Frank KJ, Lloyd R, Adriaenssen L, Bevernage J, De Zwart L, Swerts D, Tistaert C, Van Den Bergh A, Van Peer A, Beato S, Nguyen-Trung AT, Bennett J, McAllister M, Wong M, Zane P, Ollier C, Vicat P, Kolhmann M, Marker A, Brun P, Mazuir F, Beilles S, Venczel M, Boulenc X, Loos P, Lennernäs H, Abrahamsson B.

Eur J Pharm Sci. 2017 Jan 1;96:598-609. doi: 10.1016/j.ejps.2016.09.027. Epub 2016 Sep 23.

PMID:
27671970
8.

Comment on "In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-Based Absorption Models".

Turner DB, Liu B, Patel N, Pathak SM, Polak S, Jamei M, Dressman J, Rostami-Hodjegan A.

Mol Pharm. 2017 Jan 3;14(1):336-339. doi: 10.1021/acs.molpharmaceut.6b00469. Epub 2016 Dec 16. No abstract available.

PMID:
27392013
9.

The clinical and demographic profile of male patients with alcohol dependence syndrome.

Reddy MP, Babu RS, Pathak SM, Venkateshwarlu S.

Indian J Psychol Med. 2014 Oct;36(4):418-21. doi: 10.4103/0253-7176.140735.

10.

An epidemiological study of road traffic accident cases admitted in a tertiary care hospital.

Pathak SM, Jindal AK, Verma AK, Mahen A.

Med J Armed Forces India. 2014 Jan;70(1):32-5. doi: 10.1016/j.mjafi.2013.04.012. Epub 2013 Aug 30.

11.

Critical attributes of transdermal drug delivery system (TDDS)--a generic product development review.

Ruby PK, Pathak SM, Aggarwal D.

Drug Dev Ind Pharm. 2014 Nov;40(11):1421-8. doi: 10.3109/03639045.2013.879720. Epub 2014 Jan 27. Review.

PMID:
24467407
12.

In vitro and in vivo equivalence testing of nanoparticulate intravenous formulations.

Pathak SM, Ruby PK, Aggarwal D.

Drug Res (Stuttg). 2014 Apr;64(4):169-76. doi: 10.1055/s-0033-1357204. Epub 2013 Nov 7.

PMID:
24203084
13.

Establishment of in vitro-in vivo equivalence of highly variable drugs - a generic product development perspective.

Pathak SM, Aggarwal D, Venkateswarlu V.

Pharm Dev Technol. 2014 Jun;19(4):401-10. doi: 10.3109/10837450.2013.788513. Epub 2013 Apr 22.

PMID:
23607272
14.

Novel liquid chromatographic method for simultaneous estimation of pioglitazone and glimepiride in rat plasma by solid phase extraction: application to preclinical pharmacokinetic studies.

Musmade PB, Talole KB, Deshpande PB, Karthik A, Pathak SM, Pandey S, Udupa N.

Arzneimittelforschung. 2011;61(1):23-31. doi: 10.1055/s-0031-1296164.

PMID:
21355443
15.

Validated HPLC method for quantitative determination of talinolol in rat plasma and application to a preclinical pharmacokinetic study.

Pathak SM, Musmade PB, Bhat KM, Udupa N.

Bioanalysis. 2010 Jan;2(1):95-104. doi: 10.4155/bio.09.162.

PMID:
21083123
16.

Enhanced oral absorption of saquinavir with Methyl-Beta-Cyclodextrin-Preparation and in vitro and in vivo evaluation.

Pathak SM, Musmade P, Dengle S, Karthik A, Bhat K, Udupa N.

Eur J Pharm Sci. 2010 Nov 20;41(3-4):440-51. doi: 10.1016/j.ejps.2010.07.013. Epub 2010 Jul 23.

PMID:
20656025
17.

Pre-clinical evidence of enhanced oral bioavailability of the P-glycoprotein substrate talinolol in combination with morin.

Pathak SM, Udupa N.

Biopharm Drug Dispos. 2010 Mar;31(2-3):202-14. doi: 10.1002/bdd.703.

PMID:
20238375
18.

An exploratory analysis of the impact of family functioning on treatment for depression in adolescents.

Feeny NC, Silva SG, Reinecke MA, McNulty S, Findling RL, Rohde P, Curry JF, Ginsburg GS, Kratochvil CJ, Pathak SM, May DE, Kennard BD, Simons AD, Wells KC, Robins M, Rosenberg D, March JS.

J Clin Child Adolesc Psychol. 2009 Nov;38(6):814-25. doi: 10.1080/15374410903297148.

19.

A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.

Pathak SM, Kumar AR, Musmade P, Udupa N.

Talanta. 2008 Jul 15;76(2):338-46. doi: 10.1016/j.talanta.2008.02.047. Epub 2008 Mar 13.

PMID:
18585287
20.
21.

The effect of various drugs on maternal serum cystine aminopeptidase.

Himaya A, Pathak SM, Nuyens AJ, Krzaniak S, Taylor GO.

Eur J Obstet Gynecol Reprod Biol. 1977;7(6):377-82.

PMID:
264065

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