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Items: 1 to 50 of 57

1.

SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.

Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ.

Nat Rev Neurol. 2019 Jul;15(7):419-427. doi: 10.1038/s41582-019-0222-0. Epub 2019 Jun 20. Review.

PMID:
31222062
2.

Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy.

Firth NC, Primativo S, Marinescu RV, Shakespeare TJ, Suarez-Gonzalez A, Lehmann M, Carton A, Ocal D, Pavisic I, Paterson RW, Slattery CF, Foulkes AJM, Ridha BH, Gil-Néciga E, Oxtoby NP, Young AL, Modat M, Cardoso MJ, Ourselin S, Ryan NS, Miller BL, Rabinovici GD, Warrington EK, Rossor MN, Fox NC, Warren JD, Alexander DC, Schott JM, Yong KXX, Crutch SJ.

Brain. 2019 Jun 20. pii: awz136. doi: 10.1093/brain/awz136. [Epub ahead of print]

3.

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

Bridel C, van Wieringen WN, Zetterberg H, Tijms BM, Teunissen CE; and the NFL Group, Alvarez-Cermeño JC, Andreasson U, Axelsson M, Bäckström DC, Bartos A, Bjerke M, Blennow K, Boxer A, Brundin L, Burman J, Christensen T, Fialová L, Forsgren L, Frederiksen JL, Gisslén M, Gray E, Gunnarsson M, Hall S, Hansson O, Herbert MK, Jakobsson J, Jessen-Krut J, Janelidze S, Johannsson G, Jonsson M, Kappos L, Khademi M, Khalil M, Kuhle J, Landén M, Leinonen V, Logroscino G, Lu CH, Lycke J, Magdalinou NK, Malaspina A, Mattsson N, Meeter LH, Mehta SR, Modvig S, Olsson T, Paterson RW, Pérez-Santiago J, Piehl F, Pijnenburg YAL, Pyykkö OT, Ragnarsson O, Rojas JC, Romme Christensen J, Sandberg L, Scherling CS, Schott JM, Sellebjerg FT, Simone IL, Skillbäck T, Stilund M, Sundström P, Svenningsson A, Tortelli R, Tortorella C, Trentini A, Troiano M, Turner MR, van Swieten JC, Vågberg M, Verbeek MM, Villar LM, Visser PJ, Wallin A, Weiss A, Wikkelsø C, Wild EJ.

JAMA Neurol. 2019 Jun 17. doi: 10.1001/jamaneurol.2019.1534. [Epub ahead of print]

PMID:
31206160
4.

Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest.

Foiani MS, Cicognola C, Ermann N, Woollacott IOC, Heller C, Heslegrave AJ, Keshavan A, Paterson RW, Ye K, Kornhuber J, Fox NC, Schott JM, Warren JD, Lewczuk P, Zetterberg H, Blennow K, Höglund K, Rohrer JD.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):740-746. doi: 10.1136/jnnp-2018-319266. Epub 2019 Apr 13.

5.

Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.

Arber C, Toombs J, Lovejoy C, Ryan NS, Paterson RW, Willumsen N, Gkanatsiou E, Portelius E, Blennow K, Heslegrave A, Schott JM, Hardy J, Lashley T, Fox NC, Zetterberg H, Wray S.

Mol Psychiatry. 2019 Apr 12. doi: 10.1038/s41380-019-0410-8. [Epub ahead of print]

PMID:
30980041
6.

The functional neuroanatomy of musical memory in Alzheimer's disease.

Slattery CF, Agustus JL, Paterson RW, McCallion O, Foulkes AJM, Macpherson K, Carton AM, Harding E, Golden HL, Jaisin K, Mummery CJ, Schott JM, Warren JD.

Cortex. 2019 Jun;115:357-370. doi: 10.1016/j.cortex.2019.02.003. Epub 2019 Feb 15.

7.

Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's disease.

Parker TD, Slattery CF, Yong KXX, Nicholas JM, Paterson RW, Foulkes AJM, Malone IB, Thomas DL, Cash DM, Crutch SJ, Fox NC, Schott JM.

Neuroimage Clin. 2019;21:101632. doi: 10.1016/j.nicl.2018.101632. Epub 2018 Dec 11.

8.

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup.

Woollacott IOC, Nicholas JM, Heslegrave A, Heller C, Foiani MS, Dick KM, Russell LL, Paterson RW, Keshavan A, Fox NC, Warren JD, Schott JM, Zetterberg H, Rohrer JD.

Alzheimers Res Ther. 2018 Aug 16;10(1):79. doi: 10.1186/s13195-018-0405-8.

9.

Navigational cue effects in Alzheimer's disease and posterior cortical atrophy.

Yong KXX, McCarthy ID, Poole T, Suzuki T, Yang B, Carton AM, Holloway C, Papadosifos N, Boampong D, Langham J, Slattery CF, Paterson RW, Foulkes AJM, Schott JM, Frost C, Tyler N, Crutch SJ.

Ann Clin Transl Neurol. 2018 Apr 20;5(6):697-709. doi: 10.1002/acn3.566. eCollection 2018 Jun.

10.

Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios.

Toombs J, Foiani MS, Wellington H, Paterson RW, Arber C, Heslegrave A, Lunn MP, Schott JM, Wray S, Zetterberg H.

Alzheimers Dement (Amst). 2018 Mar 22;10:311-321. doi: 10.1016/j.dadm.2018.02.005. eCollection 2018.

11.

Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging.

Parker TD, Slattery CF, Zhang J, Nicholas JM, Paterson RW, Foulkes AJM, Malone IB, Thomas DL, Modat M, Cash DM, Crutch SJ, Alexander DC, Ourselin S, Fox NC, Zhang H, Schott JM.

Hum Brain Mapp. 2018 Jul;39(7):3005-3017. doi: 10.1002/hbm.24056. Epub 2018 Mar 25.

12.

Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.

Paterson RW, Slattery CF, Poole T, Nicholas JM, Magdalinou NK, Toombs J, Chapman MD, Lunn MP, Heslegrave AJ, Foiani MS, Weston PSJ, Keshavan A, Rohrer JD, Rossor MN, Warren JD, Mummery CJ, Blennow K, Fox NC, Zetterberg H, Schott JM.

Alzheimers Res Ther. 2018 Mar 20;10(1):32. doi: 10.1186/s13195-018-0361-3.

13.

CSF neurogranin or tau distinguish typical and atypical Alzheimer disease.

Wellington H, Paterson RW, Suárez-González A, Poole T, Frost C, Sjöbom U, Slattery CF, Magdalinou NK, Lehmann M, Portelius E, Fox NC, Blennow K, Zetterberg H, Schott JM.

Ann Clin Transl Neurol. 2018 Jan 11;5(2):162-171. doi: 10.1002/acn3.518. eCollection 2018 Feb.

14.

Inhibiting the Ca2+ Influx Induced by Human CSF.

Drews A, De S, Flagmeier P, Wirthensohn DC, Chen WH, Whiten DR, Rodrigues M, Vincke C, Muyldermans S, Paterson RW, Slattery CF, Fox NC, Schott JM, Zetterberg H, Dobson CM, Gandhi S, Klenerman D.

Cell Rep. 2017 Dec 12;21(11):3310-3316. doi: 10.1016/j.celrep.2017.11.057.

15.

Music models aberrant rule decoding and reward valuation in dementia.

Clark CN, Golden HL, McCallion O, Nicholas JM, Cohen MH, Slattery CF, Paterson RW, Fletcher PD, Mummery CJ, Rohrer JD, Crutch SJ, Warren JD.

Soc Cogn Affect Neurosci. 2018 Feb 1;13(2):192-202. doi: 10.1093/scan/nsx140.

16.

Eyetracking Metrics in Young Onset Alzheimer's Disease: A Window into Cognitive Visual Functions.

Pavisic IM, Firth NC, Parsons S, Rego DM, Shakespeare TJ, Yong KXX, Slattery CF, Paterson RW, Foulkes AJM, Macpherson K, Carton AM, Alexander DC, Shawe-Taylor J, Fox NC, Schott JM, Crutch SJ, Primativo S.

Front Neurol. 2017 Aug 7;8:377. doi: 10.3389/fneur.2017.00377. eCollection 2017.

17.

ApoE influences regional white-matter axonal density loss in Alzheimer's disease.

Slattery CF, Zhang J, Paterson RW, Foulkes AJM, Carton A, Macpherson K, Mancini L, Thomas DL, Modat M, Toussaint N, Cash DM, Thornton JS, Henley SMD, Crutch SJ, Alexander DC, Ourselin S, Fox NC, Zhang H, Schott JM.

Neurobiol Aging. 2017 Sep;57:8-17. doi: 10.1016/j.neurobiolaging.2017.04.021. Epub 2017 May 3.

18.

Effect of Spinal Manometers on Cerebrospinal Fluid Amyloid-β Concentration.

Toombs J, Foiani MS, Paterson RW, Heslegrave A, Wray S, Schott JM, Fox NC, Lunn MP, Blennow K, Zetterberg H.

J Alzheimers Dis. 2017;56(3):885-891. doi: 10.3233/JAD-161126.

PMID:
28059797
19.

A targeted proteomic multiplex CSF assay identifies increased malate dehydrogenase and other neurodegenerative biomarkers in individuals with Alzheimer's disease pathology.

Paterson RW, Heywood WE, Heslegrave AJ, Magdalinou NK, Andreasson U, Sirka E, Bliss E, Slattery CF, Toombs J, Svensson J, Johansson P, Fox NC, Zetterberg H, Mills K, Schott JM.

Transl Psychiatry. 2016 Nov 15;6(11):e952. doi: 10.1038/tp.2016.194.

20.

Music Perception in Dementia.

Golden HL, Clark CN, Nicholas JM, Cohen MH, Slattery CF, Paterson RW, Foulkes AJM, Schott JM, Mummery CJ, Crutch SJ, Warren JD.

J Alzheimers Dis. 2017;55(3):933-949. doi: 10.3233/JAD-160359.

21.

Diagnosing Dementia in the Clinical Setting: Can Amyloid PET Provide Additional Value Over Cerebrospinal Fluid?

Weston PS, Paterson RW, Dickson J, Barnes A, Bomanji JB, Kayani I, Lunn MP, Mummery CJ, Warren JD, Rossor MN, Fox NC, Zetterberg H, Schott JM.

J Alzheimers Dis. 2016 Oct 18;54(4):1297-1302.

22.

Effect of age at onset on cortical thickness and cognition in posterior cortical atrophy.

Suárez-González A, Lehmann M, Shakespeare TJ, Yong KXX, Paterson RW, Slattery CF, Foulkes AJM, Rabinovici GD, Gil-Néciga E, Roldán-Lora F, Schott JM, Fox NC, Crutch SJ.

Neurobiol Aging. 2016 Aug;44:108-113. doi: 10.1016/j.neurobiolaging.2016.04.012. Epub 2016 Apr 25.

23.

Do cerebrospinal fluid transfer methods affect measured amyloid β42, total tau, and phosphorylated tau in clinical practice?

Paterson RW, Toombs J, Chapman MD, Nicholas JM, Heslegrave AJ, Slattery CF, Foulkes AJ, Clark CN, Lane CA, Weston PS, Lunn MP, Fox NC, Zetterberg H, Schott JM.

Alzheimers Dement (Amst). 2015 Jul 2;1(3):380-4. doi: 10.1016/j.dadm.2015.06.003. eCollection 2015 Sep.

24.

Significant cognitive improvement with cholinesterase inhibition in AD with cerebral amyloid angiopathy.

Paterson RW, Abdi Z, Haines A, Schott JM.

Clin Neurol Neurosurg. 2016 May;144:64-6. doi: 10.1016/j.clineuro.2016.02.036. Epub 2016 Mar 3. No abstract available.

PMID:
26989943
25.

Erratum to: Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay.

Heywood WE, Galimberti D, Bliss E, Sirka E, Paterson RW, Magdalinou NK, Carecchio M, Reid E, Heslegrave A, Fenoglio C, Scarpini E, Schott JM, Fox NC, Hardy J, Bhatia KP, Heales S, Sebire NJ, Zetterberg H, Mills K.

Mol Neurodegener. 2016 Feb 23;11:20. doi: 10.1186/s13024-016-0086-3. No abstract available.

26.

Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes.

Weston PS, Paterson RW, Modat M, Burgos N, Cardoso MJ, Magdalinou N, Lehmann M, Dickson JC, Barnes A, Bomanji JB, Kayani I, Cash DM, Ourselin S, Toombs J, Lunn MP, Mummery CJ, Warren JD, Rossor MN, Fox NC, Zetterberg H, Schott JM.

Alzheimers Dement (Amst). 2015 Nov 2;1(4):440-446. eCollection 2015 Dec.

27.

Increased CSF neurogranin concentration is specific to Alzheimer disease.

Wellington H, Paterson RW, Portelius E, Törnqvist U, Magdalinou N, Fox NC, Blennow K, Schott JM, Zetterberg H.

Neurology. 2016 Mar 1;86(9):829-35. doi: 10.1212/WNL.0000000000002423. Epub 2016 Jan 29.

28.

Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay.

Heywood WE, Galimberti D, Bliss E, Sirka E, Paterson RW, Magdalinou NK, Carecchio M, Reid E, Heslegrave A, Fenoglio C, Scarpini E, Schott JM, Fox NC, Hardy J, Bhatia K, Heales S, Sebire NJ, Zetterberg H, Mills K.

Mol Neurodegener. 2015 Dec 1;10:64. doi: 10.1186/s13024-015-0059-y. Erratum in: Mol Neurodegener. 2016;11:20. Bahtia, Kailash and Zetterburg, Henrik [Corrected to Bhatia, Kailash and Zetterberg, Henrik].

29.

Pain and temperature processing in dementia: a clinical and neuroanatomical analysis.

Fletcher PD, Downey LE, Golden HL, Clark CN, Slattery CF, Paterson RW, Rohrer JD, Schott JM, Rossor MN, Warren JD.

Brain. 2015 Nov;138(Pt 11):3360-72. doi: 10.1093/brain/awv276. Epub 2015 Oct 12.

30.

Dissecting IWG-2 typical and atypical Alzheimer's disease: insights from cerebrospinal fluid analysis.

Paterson RW, Toombs J, Slattery CF, Nicholas JM, Andreasson U, Magdalinou NK, Blennow K, Warren JD, Mummery CJ, Rossor MN, Lunn MP, Crutch SJ, Fox NC, Zetterberg H, Schott JM.

J Neurol. 2015 Dec;262(12):2722-30. doi: 10.1007/s00415-015-7904-3. Epub 2015 Sep 26.

PMID:
26410752
31.

The impact of Tween 20 on repeatability of amyloid β and tau measurements in cerebrospinal fluid.

Toombs J, Paterson RW, Nicholas JM, Petzold A, Schott JM, Zetterberg H.

Clin Chem Lab Med. 2015 Nov;53(12):e329-32. doi: 10.1515/cclm-2015-0414. No abstract available.

32.

Auditory hedonic phenotypes in dementia: A behavioural and neuroanatomical analysis.

Fletcher PD, Downey LE, Golden HL, Clark CN, Slattery CF, Paterson RW, Schott JM, Rohrer JD, Rossor MN, Warren JD.

Cortex. 2015 Jun;67:95-105. doi: 10.1016/j.cortex.2015.03.021. Epub 2015 Apr 8.

33.

Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy.

Shakespeare TJ, Kaski D, Yong KX, Paterson RW, Slattery CF, Ryan NS, Schott JM, Crutch SJ.

Brain. 2015 Jul;138(Pt 7):1976-91. doi: 10.1093/brain/awv103. Epub 2015 Apr 19.

34.

A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes.

Magdalinou NK, Paterson RW, Schott JM, Fox NC, Mummery C, Blennow K, Bhatia K, Morris HR, Giunti P, Warner TT, de Silva R, Lees AJ, Zetterberg H.

J Neurol Neurosurg Psychiatry. 2015 Nov;86(11):1240-7. doi: 10.1136/jnnp-2014-309562. Epub 2015 Jan 14.

35.

Biomarkers in dementia: clinical utility and new directions.

Ahmed RM, Paterson RW, Warren JD, Zetterberg H, O'Brien JT, Fox NC, Halliday GM, Schott JM.

J Neurol Neurosurg Psychiatry. 2014 Dec;85(12):1426-34. doi: 10.1136/jnnp-2014-307662. Epub 2014 Sep 26. Review.

36.

Clinical relevance of serum antibodies to extracellular N-methyl-D-aspartate receptor epitopes.

Zandi MS, Paterson RW, Ellul MA, Jacobson L, Al-Diwani A, Jones JL, Cox AL, Lennox B, Stamelou M, Bhatia KP, Schott JM, Coles AJ, Kullmann DM, Vincent A.

J Neurol Neurosurg Psychiatry. 2015 Jul;86(7):708-13. doi: 10.1136/jnnp-2014-308736. Epub 2014 Sep 22.

37.

Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals.

Paterson RW, Bartlett JW, Blennow K, Fox NC; Alzheimer's Disease Neuroimaging Initiative, Shaw LM, Trojanowski JQ, Zetterberg H, Schott JM.

Transl Psychiatry. 2014 Jul 29;4:e419. doi: 10.1038/tp.2014.58.

38.

Amyloid-beta 42 adsorption following serial tube transfer.

Toombs J, Paterson RW, Schott JM, Zetterberg H.

Alzheimers Res Ther. 2014 Jan 28;6(1):5. doi: 10.1186/alzrt236. eCollection 2014.

39.

Biomarker modelling of early molecular changes in Alzheimer's disease.

Paterson RW, Toombs J, Slattery CF, Schott JM, Zetterberg H.

Mol Diagn Ther. 2014 Apr;18(2):213-27. doi: 10.1007/s40291-013-0069-9. Review.

PMID:
24281842
40.

Identification of an important potential confound in CSF AD studies: aliquot volume.

Toombs J, Paterson RW, Lunn MP, Nicholas JM, Fox NC, Chapman MD, Schott JM, Zetterberg H.

Clin Chem Lab Med. 2013 Dec;51(12):2311-7. doi: 10.1515/cclm-2013-0293.

41.

Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: experience from a tertiary referral centre.

Paterson RW, Zandi MS, Armstrong R, Vincent A, Schott JM.

J Neurol Neurosurg Psychiatry. 2014 Jun;85(6):625-30. doi: 10.1136/jnnp-2013-305218. Epub 2013 Jun 11.

42.

Recurrent stereotyped episodes in cerebral amyloid angiopathy: response to migraine prophylaxis in two patients.

Paterson RW, Uchino K, Emsley HC, Pullicino P.

Cerebrovasc Dis Extra. 2013 May 18;3(1):81-4. doi: 10.1159/000347114. Print 2013 Jan.

43.

Diagnosis and treatment of rapidly progressive dementias.

Paterson RW, Takada LT, Geschwind MD.

Neurol Clin Pract. 2012 Sep;2(3):187-200.

44.

The European Association of Young Neurologists and Trainees in 2013: striking a blow for European junior neurologists.

Macerollo A, Varga ET, Györfi O, Kobeleva X, Paterson RW, Sellner J.

Eur J Neurol. 2013 Apr;20(4):e54-8. doi: 10.1111/ene.12114.

PMID:
23490115
45.

Subacute peripheral and optic neuropathy syndrome with no evidence of a toxic or nutritional cause.

Allen D, Riordan-Eva P, Paterson RW, Hadden RD.

Clin Neurol Neurosurg. 2013 Aug;115(8):1389-93. doi: 10.1016/j.clineuro.2013.01.002. Epub 2013 Feb 4.

PMID:
23384546
46.

Differential diagnosis of Jakob-Creutzfeldt disease.

Paterson RW, Torres-Chae CC, Kuo AL, Ando T, Nguyen EA, Wong K, DeArmond SJ, Haman A, Garcia P, Johnson DY, Miller BL, Geschwind MD.

Arch Neurol. 2012 Dec;69(12):1578-82. doi: 10.1001/2013.jamaneurol.79.

47.

Career mentorship for young neurologists in Europe.

Paterson RW, Waldermar G, Chaudhuri KR, Varga ET, Sztriha LK, Sellner J, Sauerbier A, Kondziella D, Macerollo A, Valkovic P, Oertel WH.

Neurology. 2012 Jul 24;79(4):381-3. doi: 10.1212/WNL.0b013e318260cdd7. No abstract available.

PMID:
22826543
48.

Heterogeneity in preferences for smoking cessation.

Paterson RW, Boyle KJ, Parmeter CF, Neumann JE, De Civita P.

Health Econ. 2008 Dec;17(12):1363-77. doi: 10.1002/hec.1336.

PMID:
18189227
49.

Drug-induced meningitis.

Wong JG, Hathaway SC, Paat JJ, Paterson RW, Steele GH Jr.

Postgrad Med. 1994 Dec;96(6):117-124. doi: 10.1080/00325481.1994.11945926.

PMID:
29211590
50.

Drug-induced meningitis. A case involving trimethoprim-sulfamethoxazole.

Wong JG, Hathaway SC, Paat JJ, Paterson RW, Steele GH Jr.

Postgrad Med. 1994 Nov 1;96(6):117-8, 121,124.

PMID:
7971606

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