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Items: 1 to 50 of 432

1.

Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and α1 receptor antagonists.

Heng HL, Chee CF, Chin SP, Ouyang Y, Wang H, Buckle MJC, Herr DR, Paterson IC, Doughty SW, Abd Rahman N, Chung LY.

Medchemcomm. 2018 Feb 26;9(3):576-582. doi: 10.1039/c7md00629b. eCollection 2018 Mar 1.

PMID:
30108948
2.

The Dynamic Roles of TGF-β Signalling in EBV-Associated Cancers.

Velapasamy S, Dawson CW, Young LS, Paterson IC, Yap LF.

Cancers (Basel). 2018 Jul 27;10(8). pii: E247. doi: 10.3390/cancers10080247. Review.

3.

Corrigendum: A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.

Melling GE, Flannery SE, Abidin SA, Clemmens H, Prajapati P, Hinsley EE, Hunt S, Catto JWF, Coletta RD, Mellone M, Thomas GJ, Parkinson EK, Prime SS, Paterson IC, Buttle DJ, Lambert DW.

Carcinogenesis. 2018 Jul 4. doi: 10.1093/carcin/bgy083. [Epub ahead of print] No abstract available.

PMID:
29982353
4.

Clinico-pathological features of oropharyngeal squamous cell carcinomas in Malaysia with reference to HPV infection.

Yap LF, Lai SL, Rhodes A, Sathasivam HP, Abdullah MA, Pua KC, Rajadurai P, Cheah PL, Thavaraj S, Robinson M, Paterson IC.

Infect Agent Cancer. 2018 Jun 11;13:21. doi: 10.1186/s13027-018-0193-6. eCollection 2018.

5.

Genotyping-by-sequencing of genome-wide microsatellite loci reveals fine-scale harvest composition in a coastal Atlantic salmon fishery.

Bradbury IR, Wringe BF, Watson B, Paterson I, Horne J, Beiko R, Lehnert SJ, Clément M, Anderson EC, Jeffery NW, Duffy S, Sylvester E, Robertson M, Bentzen P.

Evol Appl. 2018 Mar 11;11(6):918-930. doi: 10.1111/eva.12606. eCollection 2018 Jul.

6.

Comparison of epicardial adipose tissue radiodensity threshold between contrast and non-contrast enhanced computed tomography scans: A cohort study of derivation and validation.

Xu L, Xu Y, Coulden R, Sonnex E, Hrybouski S, Paterson I, Butler C.

Atherosclerosis. 2018 May 11;275:74-79. doi: 10.1016/j.atherosclerosis.2018.05.013. [Epub ahead of print]

PMID:
29864608
7.

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.

Menchon G, Prota AE, Lucena-Agell D, Bucher P, Jansen R, Irschik H, Müller R, Paterson I, Díaz JF, Altmann KH, Steinmetz MO.

Nat Commun. 2018 May 29;9(1):2106. doi: 10.1038/s41467-018-04535-8.

8.

What is the minimum change in left ventricular ejection fraction, which can be measured with contrast echocardiography?

Suwatanaviroj T, He W, Pituskin E, Paterson I, Choy J, Becher H.

Echo Res Pract. 2018 Jun;5(2):71-77. doi: 10.1530/ERP-18-0003. Epub 2018 Apr 11.

9.

Expansive reed populations-alien invasion or disturbed wetlands?

Canavan K, Paterson ID, Lambertini C, Hill MP.

AoB Plants. 2018 Feb 23;10(2):ply014. doi: 10.1093/aobpla/ply014. eCollection 2018 Mar.

10.

A synthesis-enabled relative stereochemical assignment of the C1-C28 region of hemicalide.

Han BY, Lam NYS, MacGregor CI, Goodman JM, Paterson I.

Chem Commun (Camb). 2018 Mar 27;54(26):3247-3250. doi: 10.1039/c8cc00933c.

PMID:
29536067
11.

A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.

Melling GE, Flannery SE, Abidin SA, Clemmens H, Prajapati P, Hinsley EE, Hunt S, Catto JWF, Coletta RD, Mellone M, Thomas GJ, Parkinson EK, Prime SS, Paterson IC, Buttle DJ, Lambert DW.

Carcinogenesis. 2018 May 28;39(6):798-807. doi: 10.1093/carcin/bgy032.

PMID:
29506142
12.

Chloroquine-induced cardiomyopathy: a reversible cause of heart failure.

Yogasundaram H, Hung W, Paterson ID, Sergi C, Oudit GY.

ESC Heart Fail. 2018 Jun;5(3):372-375. doi: 10.1002/ehf2.12276. Epub 2018 Feb 20.

13.

Toward aplyronine payloads for antibody-drug conjugates: total synthesis of aplyronines A and D.

AnŽiček N, Williams S, Housden MP, Paterson I.

Org Biomol Chem. 2018 Feb 21;16(8):1343-1350. doi: 10.1039/c7ob03204h.

PMID:
29393939
14.

Home Exercise Training Improves Exercise Capacity in Cirrhosis Patients: Role of Exercise Adherence.

Kruger C, McNeely ML, Bailey RJ, Yavari M, Abraldes JG, Carbonneau M, Newnham K, DenHeyer V, Ma M, Thompson R, Paterson I, Haykowsky MJ, Tandon P.

Sci Rep. 2018 Jan 8;8(1):99. doi: 10.1038/s41598-017-18320-y.

15.

Variability of left ventricular volume and ejection fraction measurements using contrast echocardiography: The influence of the left ventricular length measurements in a large cohort of patients during monitoring cardiotoxic effects of chemotherapy.

Suwatanaviroj T, He W, Mirhadi E, Paakanen R, Pituskin E, Paterson I, Choy J, Becher H.

Echocardiography. 2018 Mar;35(3):322-328. doi: 10.1111/echo.13783. Epub 2017 Dec 22.

PMID:
29272561
16.

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.

Michelakis ED, Gurtu V, Webster L, Barnes G, Watson G, Howard L, Cupitt J, Paterson I, Thompson RB, Chow K, O'Regan DP, Zhao L, Wharton J, Kiely DG, Kinnaird A, Boukouris AE, White C, Nagendran J, Freed DH, Wort SJ, Gibbs JSR, Wilkins MR.

Sci Transl Med. 2017 Oct 25;9(413). pii: eaao4583. doi: 10.1126/scitranslmed.aao4583.

17.

Challenges and discoveries in the total synthesis of complex polyketide natural products.

Paterson I, Lam NYS.

J Antibiot (Tokyo). 2018 Feb;71(2):215-233. doi: 10.1038/ja.2017.111. Epub 2017 Oct 25. Review.

PMID:
29066790
18.

Subclinical Pulmonary Edema Is Associated With Reduced Exercise Capacity in HFpEF and HFrEF.

Thompson RB, Pagano JJ, Chow K, Sekowski V, Paterson I, Ezekowitz J, Anderson T, Dyck JRB, Haykowsky MJ; Alberta HEART investigators.

J Am Coll Cardiol. 2017 Oct 3;70(14):1827-1828. doi: 10.1016/j.jacc.2017.07.787. No abstract available.

PMID:
28958338
19.

The Role of Cardio-Oncology in the Interprofessional Care of Adult Patients Receiving Cancer Therapy.

Pituskin E, Paterson I, Cox-Kennett N, Rothe D, Perri M, Becher H.

Semin Oncol Nurs. 2017 Nov;33(4):384-392. doi: 10.1016/j.soncn.2017.08.010. Epub 2017 Sep 21. Review.

PMID:
28941563
20.

A prospective evaluation of the established criteria for heart failure with preserved ejection fraction using the Alberta HEART cohort.

Ezekowitz JA, McAlister FA, Howlett J, Alemayehu W, Paterson I, Belenkie I, Oudit GY, Kaul P, Dyck JR, Anderson T; Alberta HEART Investigators.

ESC Heart Fail. 2018 Feb;5(1):19-26. doi: 10.1002/ehf2.12200. Epub 2017 Jul 25.

21.

Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.

Chan A, Gilfillan C, Templeton N, Paterson I, Northcote PT, Miller JH.

Invest New Drugs. 2017 Dec;35(6):706-717. doi: 10.1007/s10637-017-0493-5. Epub 2017 Jul 22.

PMID:
28733703
22.

Distinct Biological Potential of Streptococcus gordonii and Streptococcus sanguinis Revealed by Comparative Genome Analysis.

Zheng W, Tan MF, Old LA, Paterson IC, Jakubovics NS, Choo SW.

Sci Rep. 2017 Jun 7;7(1):2949. doi: 10.1038/s41598-017-02399-4.

23.

Beta blockers and improved progression-free survival in patients with advanced HER2 negative breast cancer: a retrospective analysis of the ROSE/TRIO-012 study.

Spera G, Fresco R, Fung H, Dyck JRB, Pituskin E, Paterson I, Mackey JR.

Ann Oncol. 2017 Aug 1;28(8):1836-1841. doi: 10.1093/annonc/mdx264.

PMID:
28520849
24.

Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.

Field JJ, Northcote PT, Paterson I, Altmann KH, Díaz JF, Miller JH.

Int J Mol Sci. 2017 May 3;18(5). pii: E971. doi: 10.3390/ijms18050971.

25.

Synthesis and biological evaluation of indole core-based derivatives with potent antibacterial activity against resistant bacterial pathogens.

Hong W, Li J, Chang Z, Tan X, Yang H, Ouyang Y, Yang Y, Kaur S, Paterson IC, Ngeow YF, Wang H.

J Antibiot (Tokyo). 2017 Jul;70(7):832-844. doi: 10.1038/ja.2017.55. Epub 2017 May 3.

PMID:
28465626
26.

Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming.

Verusingam ND, Yeap SK, Ky H, Paterson IC, Khoo SP, Cheong SK, Ong AHK, Kamarul T.

PeerJ. 2017 Apr 13;5:e3174. doi: 10.7717/peerj.3174. eCollection 2017.

27.

Mechanisms of sphingosine 1-phosphate receptor signalling in cancer.

Patmanathan SN, Wang W, Yap LF, Herr DR, Paterson IC.

Cell Signal. 2017 Jun;34:66-75. doi: 10.1016/j.cellsig.2017.03.002. Epub 2017 Mar 14. Review.

PMID:
28302566
28.

Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.

Lee HM, Lo KW, Wei W, Tsao SW, Chung GTY, Ibrahim MH, Dawson CW, Murray PG, Paterson IC, Yap LF.

J Pathol. 2017 May;242(1):62-72. doi: 10.1002/path.4879. Epub 2017 Mar 15.

29.

Structural Basis of Microtubule Stabilization by Discodermolide.

Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB 3rd, Yang CH, McDaid HM, Paterson I, Horwitz SB, Fernando Díaz J, Steinmetz MO.

Chembiochem. 2017 May 18;18(10):905-909. doi: 10.1002/cbic.201600696. Epub 2017 Mar 27.

30.

Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.

Trigili C, Barasoain I, Sánchez-Murcia PA, Bargsten K, Redondo-Horcajo M, Nogales A, Gardner NM, Meyer A, Naylor GJ, Gómez-Rubio E, Gago F, Steinmetz MO, Paterson I, Prota AE, Díaz JF.

ACS Omega. 2016 Dec 31;1(6):1192-1204. doi: 10.1021/acsomega.6b00317. Epub 2016 Dec 13.

31.

HOPX functions as a tumour suppressor in head and neck cancer.

Yap LF, Lai SL, Patmanathan SN, Gokulan R, Robinson CM, White JB, Chai SJ, Rajadurai P, Prepageran N, Liew YT, Lopes V, Wei W, Hollows RJ, Murray PG, Lambert DW, Hunter KD, Paterson IC.

Sci Rep. 2016 Dec 9;6:38758. doi: 10.1038/srep38758.

32.

An Expedient Total Synthesis of Chivosazole F: an Actin-Binding Antimitotic Macrolide from the Myxobacterium Sorangium Cellulosum.

Williams S, Jin J, Kan SB, Li M, Gibson LJ, Paterson I.

Angew Chem Int Ed Engl. 2017 Jan 9;56(2):645-649. doi: 10.1002/anie.201610636. Epub 2016 Nov 29.

PMID:
27897365
33.

Optimising Antibiotic Usage to Treat Bacterial Infections.

Paterson IK, Hoyle A, Ochoa G, Baker-Austin C, Taylor NG.

Sci Rep. 2016 Nov 28;6:37853. doi: 10.1038/srep37853.

34.

Influenza H1N1 Infection Leading To Cardiac Tamponade in a Previously Healthy Patient: A Case Report.

Sidhu RS, Sharma A, Paterson ID, Bainey KR.

Res Cardiovasc Med. 2016 Jul 16;5(3):e31546. eCollection 2016 Aug.

35.

Differential Responses of Post-Exercise Recovery of Leg Blood Flow and Oxygen Uptake Kinetics in HFpEF versus HFrEF.

Thompson RB, Pagano JJ, Mathewson KW, Paterson I, Dyck JR, Kitzman DW, Haykowsky MJ.

PLoS One. 2016 Oct 4;11(10):e0163513. doi: 10.1371/journal.pone.0163513. eCollection 2016.

36.

Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy.

Makani V, Zhang B, Han H, Yao Y, Lassalas P, Lou K, Paterson I, Lee VM, Trojanowski JQ, Ballatore C, Smith AB 3rd, Brunden KR.

Acta Neuropathol Commun. 2016 Sep 29;4(1):106.

37.

Two in one: cryptic species discovered in biological control agent populations using molecular data and crossbreeding experiments.

Paterson ID, Mangan R, Downie DA, Coetzee JA, Hill MP, Burke AM, Downey PO, Henry TJ, Compton SG.

Ecol Evol. 2016 Jul 30;6(17):6139-50. doi: 10.1002/ece3.2297. eCollection 2016 Sep.

38.

Rationale and design of the multidisciplinary team IntervenTion in cArdio-oNcology study (TITAN).

Pituskin E, Haykowsky M, McNeely M, Mackey J, Chua N, Paterson I.

BMC Cancer. 2016 Sep 15;16(1):733. doi: 10.1186/s12885-016-2761-8.

39.

PGD: a pangolin genome hub for the research community.

Tan TK, Tan KY, Hari R, Mohamed Yusoff A, Wong GJ, Siow CC, Mutha NV, Rayko M, Komissarov A, Dobrynin P, Krasheninnikova K, Tamazian G, Paterson IC, Warren WC, Johnson WE, O'Brien SJ, Choo SW.

Database (Oxford). 2016 Sep 11;2016. pii: baw063. doi: 10.1093/database/baw063. Print 2016.

40.

Comparative Genome Analysis of Fusobacterium nucleatum.

Ang MY, Dutta A, Wee WY, Dymock D, Paterson IC, Choo SW.

Genome Biol Evol. 2016 Oct 5;8(9):2928-2938.

41.

Pangolin genomes and the evolution of mammalian scales and immunity.

Choo SW, Rayko M, Tan TK, Hari R, Komissarov A, Wee WY, Yurchenko AA, Kliver S, Tamazian G, Antunes A, Wilson RK, Warren WC, Koepfli KP, Minx P, Krasheninnikova K, Kotze A, Dalton DL, Vermaak E, Paterson IC, Dobrynin P, Sitam FT, Rovie-Ryan JJ, Johnson WE, Yusoff AM, Luo SJ, Karuppannan KV, Fang G, Zheng D, Gerstein MB, Lipovich L, O'Brien SJ, Wong GJ.

Genome Res. 2016 Oct;26(10):1312-1322. Epub 2016 Aug 10.

42.

Glycogen Storage Disease Because of a PRKAG2 Mutation Causing Severe Biventricular Hypertrophy and High-Grade Atrio-Ventricular Block.

Yogasundaram H, Paterson ID, Graham M, Sergi C, Oudit GY.

Circ Heart Fail. 2016 Aug;9(8). pii: e003367. doi: 10.1161/CIRCHEARTFAILURE.116.003367. No abstract available.

PMID:
27496753
43.

A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts.

Kabir TD, Leigh RJ, Tasena H, Mellone M, Coletta RD, Parkinson EK, Prime SS, Thomas GJ, Paterson IC, Zhou D, McCall J, Speight PM, Lambert DW.

Aging (Albany NY). 2016 Aug;8(8):1608-35. doi: 10.18632/aging.100987.

44.

Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy.

Virani SA, Dent S, Brezden-Masley C, Clarke B, Davis MK, Jassal DS, Johnson C, Lemieux J, Paterson I, Sebag IA, Simmons C, Sulpher J, Thain K, Thavendiranathan P, Wentzell JR, Wurtele N, Côté MA, Fine NM, Haddad H, Hayley BD, Hopkins S, Joy AA, Rayson D, Stadnick E, Straatman L.

Can J Cardiol. 2016 Jul;32(7):831-41. doi: 10.1016/j.cjca.2016.02.078. Epub 2016 Apr 7. Review.

PMID:
27343741
45.

megasat: automated inference of microsatellite genotypes from sequence data.

Zhan L, Paterson IG, Fraser BA, Watson B, Bradbury IR, Nadukkalam Ravindran P, Reznick D, Beiko RG, Bentzen P.

Mol Ecol Resour. 2017 Mar;17(2):247-256. doi: 10.1111/1755-0998.12561. Epub 2016 Jul 19.

PMID:
27333119
46.

Reduced Right Ventricular Native Myocardial T1 in Anderson-Fabry Disease: Comparison to Pulmonary Hypertension and Healthy Controls.

Pagano JJ, Chow K, Khan A, Michelakis E, Paterson I, Oudit GY, Thompson RB.

PLoS One. 2016 Jun 15;11(6):e0157565. doi: 10.1371/journal.pone.0157565. eCollection 2016.

47.

Fibroblast activation and senescence in oral cancer.

Prime SS, Cirillo N, Hassona Y, Lambert DW, Paterson IC, Mellone M, Thomas GJ, James EN, Parkinson EK.

J Oral Pathol Med. 2017 Feb;46(2):82-88. doi: 10.1111/jop.12456. Epub 2016 May 30. Review.

PMID:
27237745
48.

Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.

Patmanathan SN, Johnson SP, Lai SL, Panja Bernam S, Lopes V, Wei W, Ibrahim MH, Torta F, Narayanaswamy P, Wenk MR, Herr DR, Murray PG, Yap LF, Paterson IC.

Sci Rep. 2016 May 10;6:25650. doi: 10.1038/srep25650.

49.

StreptoBase: An Oral Streptococcus mitis Group Genomic Resource and Analysis Platform.

Zheng W, Tan TK, Paterson IC, Mutha NV, Siow CC, Tan SY, Old LA, Jakubovics NS, Choo SW.

PLoS One. 2016 May 3;11(5):e0151908. doi: 10.1371/journal.pone.0151908. eCollection 2016.

50.

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