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Items: 1 to 50 of 170

1.

Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-β Signaling in Murine Hepatic Stellate Cells.

Mehta KJ, Coombes JD, Briones-Orta M, Manka PP, Williams R, Patel VB, Syn WK.

Am J Med Sci. 2018 Feb;355(2):183-190. doi: 10.1016/j.amjms.2017.08.012. Epub 2017 Aug 23.

PMID:
29406047
2.

Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides.

Seipone ID, Singh R, Patel VB, Singh A, Gordon ML, Muema DM, Dheda K, Ndung'u T.

PLoS One. 2018 Feb 2;13(2):e0192060. doi: 10.1371/journal.pone.0192060. eCollection 2018.

3.

TIMP3 deficiency exacerbates iron overload-mediated cardiomyopathy and liver disease.

Zhabyeyev P, Das SK, Basu R, Shen M, Patel VB, Kassiri Z, Oudit GY.

Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H978-H990. doi: 10.1152/ajpheart.00597.2017. Epub 2018 Jan 26.

PMID:
29373036
4.

Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.

Das SK, Zhabyeyev P, Basu R, Patel VB, Dyck JRB, Kassiri Z, Oudit GY.

Biosci Rep. 2018 Jan 10;38(1). pii: BSR20171302. doi: 10.1042/BSR20171302. Print 2018 Feb 28.

PMID:
29208771
5.

Stability Indicating Liquid Chromatographic Method for Simultaneous determination of Aspirin and Omeprazole.

Patel VB, Patel AD, Shah DA.

Curr Drug Discov Technol. 2017 Oct 23. doi: 10.2174/1570163814666171023144105. [Epub ahead of print]

PMID:
29065836
6.

Possible anti-depressant effect of efavirenz and pro-depressive-like effect of voriconazole in specified doses in various experimental models of depression in mice.

Patel TK, Patel VB, Rana DG.

Pharmacol Rep. 2017 Oct;69(5):1082-1087. doi: 10.1016/j.pharep.2017.04.018. Epub 2017 May 1.

PMID:
28986123
7.

Erratum to: HFE mRNA expression is responsive to intracellular and extracellular iron loading: short communication.

Mehta KJ, Farnaud S, Patel VB.

Mol Biol Rep. 2017 Oct;44(5):405. doi: 10.1007/s11033-017-4127-y.

PMID:
28929467
8.

HFE mRNA expression is responsive to intracellular and extracellular iron loading: short communication.

Mehta KJ, Farnaud S, Patel VB.

Mol Biol Rep. 2017 Oct;44(5):399-403. doi: 10.1007/s11033-017-4123-2. Epub 2017 Aug 24. Erratum in: Mol Biol Rep. 2017 Sep 19;:.

9.

Epicardial adipose tissue as a metabolic transducer: role in heart failure and coronary artery disease.

Patel VB, Shah S, Verma S, Oudit GY.

Heart Fail Rev. 2017 Nov;22(6):889-902. doi: 10.1007/s10741-017-9644-1. Review.

PMID:
28762019
10.

Tissue Inhibitor of Matrix Metalloproteinase-1 Promotes Myocardial Fibrosis by Mediating CD63-Integrin β1 Interaction.

Takawale A, Zhang P, Patel VB, Wang X, Oudit G, Kassiri Z.

Hypertension. 2017 Jun;69(6):1092-1103. doi: 10.1161/HYPERTENSIONAHA.117.09045. Epub 2017 Apr 3.

PMID:
28373589
11.

Recombinant Human ACE2 and the Angiotensin 1-7 Axis as Potential New Therapies for Heart Failure.

Patel VB, Lezutekong JN, Chen X, Oudit GY.

Can J Cardiol. 2017 Jul;33(7):943-946. doi: 10.1016/j.cjca.2016.12.012. Epub 2016 Dec 23. Review.

PMID:
28279521
12.

Murine recombinant angiotensin-converting enzyme 2 attenuates kidney injury in experimental Alport syndrome.

Bae EH, Fang F, Williams VR, Konvalinka A, Zhou X, Patel VB, Song X, John R, Oudit GY, Pei Y, Scholey JW.

Kidney Int. 2017 Jun;91(6):1347-1361. doi: 10.1016/j.kint.2016.12.022. Epub 2017 Feb 27.

PMID:
28249676
13.

Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress.

Das SK, Patel VB, Basu R, Wang W, DesAulniers J, Kassiri Z, Oudit GY.

J Am Heart Assoc. 2017 Jan 23;6(1). pii: e003456. doi: 10.1161/JAHA.116.003456.

14.

A comparative study of CIDP in a cohort of HIV-infected and HIV-uninfected patients.

Moodley K, Bill PL, Patel VB.

Neurol Neuroimmunol Neuroinflamm. 2016 Dec 15;4(2):e315. doi: 10.1212/NXI.0000000000000315. eCollection 2017 Mar.

15.

In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration.

Mathison M, Singh VP, Chiuchiolo MJ, Sanagasetti D, Mao Y, Patel VB, Yang J, Kaminsky SM, Crystal RG, Rosengart TK.

J Thorac Cardiovasc Surg. 2017 Feb;153(2):329-339.e3. doi: 10.1016/j.jtcvs.2016.09.041. Epub 2016 Sep 23.

16.

Characterization of hepcidin response to holotransferrin in novel recombinant TfR1 HepG2 cells.

Mehta K, Busbridge M, Renshaw D, Evans RW, Farnaud S, Patel VB.

Blood Cells Mol Dis. 2016 Oct;61:37-45. doi: 10.1016/j.bcmd.2016.06.008. Epub 2016 Jun 30.

17.

Repeat-measures longitudinal study evaluating behavioural and gastrointestinal symptoms in children with autism before, during and after visceral osteopathic technique (VOT).

Bramati-Castellarin I, Patel VB, Drysdale IP.

J Bodyw Mov Ther. 2016 Jul;20(3):461-70. doi: 10.1016/j.jbmt.2016.01.001. Epub 2016 Jan 14.

PMID:
27634066
18.

ACE2/Ang 1-7 axis: A critical regulator of epicardial adipose tissue inflammation and cardiac dysfunction in obesity.

Patel VB, Basu R, Oudit GY.

Adipocyte. 2016 Jan 6;5(3):306-11. doi: 10.1080/21623945.2015.1131881. eCollection 2016 Jul-Sep.

19.

Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart Failure.

Patel VB, Zhong JC, Grant MB, Oudit GY.

Circ Res. 2016 Apr 15;118(8):1313-26. doi: 10.1161/CIRCRESAHA.116.307708. Review.

21.

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.

Das SK, Wang W, Zhabyeyev P, Basu R, McLean B, Fan D, Parajuli N, DesAulniers J, Patel VB, Hajjar RJ, Dyck JR, Kassiri Z, Oudit GY.

Sci Rep. 2015 Dec 7;5:18132. doi: 10.1038/srep18132.

22.

Regulators of G-Protein Signaling 10 and Heart Failure: The Importance of Negative Regulators of Heart Disease.

Patel VB, McLean BA, Chen X, Oudit GY.

Hypertension. 2016 Jan;67(1):38-40. doi: 10.1161/HYPERTENSIONAHA.115.06109. Epub 2015 Nov 16. No abstract available.

PMID:
26573716
23.

Interventional Therapies for Chronic Low Back Pain: A Focused Review (Efficacy and Outcomes).

Patel VB, Wasserman R, Imani F.

Anesth Pain Med. 2015 Aug 22;5(4):e29716. doi: 10.5812/aapm.29716. eCollection 2015 Aug. Review.

24.

ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity.

Patel VB, Mori J, McLean BA, Basu R, Das SK, Ramprasath T, Parajuli N, Penninger JM, Grant MB, Lopaschuk GD, Oudit GY.

Diabetes. 2016 Jan;65(1):85-95. doi: 10.2337/db15-0399. Epub 2015 Jul 29.

25.

Characterisation of hepcidin response to holotransferrin treatment in CHO TRVb-1 cells.

Mehta K, Greenwell P, Renshaw D, Busbridge M, Garcia M, Farnaud S, Patel VB.

Blood Cells Mol Dis. 2015 Aug;55(2):110-8. doi: 10.1016/j.bcmd.2015.05.002. Epub 2015 May 8.

PMID:
26142326
26.

Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules.

Pan SJ, Tapley A, Adamson J, Little T, Urbanowski M, Cohen K, Pym A, Almeida D, Dorasamy A, Layre E, Young DC, Singh R, Patel VB, Wallengren K, Ndung'u T, Wilson D, Moody DB, Bishai W.

J Infect Dis. 2015 Dec 1;212(11):1827-34. doi: 10.1093/infdis/jiv312. Epub 2015 May 26.

27.

Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2.

Patel VB, Takawale A, Ramprasath T, Das SK, Basu R, Grant MB, Hall DA, Kassiri Z, Oudit GY.

J Mol Med (Berl). 2015 Sep;93(9):1003-13. doi: 10.1007/s00109-015-1285-z. Epub 2015 Apr 15.

28.

New insights into the role of the branched-chain aminotransferase proteins in the human brain.

Hull J, Patel VB, Hutson SM, Conway ME.

J Neurosci Res. 2015 Jul;93(7):987-98. doi: 10.1002/jnr.23558. Epub 2015 Feb 2. Review.

PMID:
25639459
29.

PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.

McLean BA, Zhabyeyev P, Patel VB, Basu R, Parajuli N, DesAulniers J, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY.

Cardiovasc Res. 2015 Mar 1;105(3):292-303. doi: 10.1093/cvr/cvv016. Epub 2015 Jan 24.

PMID:
25618408
30.

Dual loss of PI3Kα and PI3Kγ signaling leads to an age-dependent cardiomyopathy.

Zhabyeyev P, McLean B, Patel VB, Wang W, Ramprasath T, Oudit GY.

J Mol Cell Cardiol. 2014 Dec;77:155-9. doi: 10.1016/j.yjmcc.2014.10.008. Epub 2014 Oct 24.

PMID:
25451171
31.

Selective omission of level V nodal coverage for patients with oropharyngeal cancer: Clinical validation of intensity-modulated radiotherapy experience and dosimetric significance.

Mohindra P, Urban E, Pagan JD, Geye HM, Patel VB, Bayliss RA, Bender ET, Harari PM.

Head Neck. 2016 Apr;38(4):499-505. doi: 10.1002/hed.23924. Epub 2015 Jun 16.

PMID:
25445257
32.

Hydrogen sulfide: an old gas with new cardioprotective effects.

Patel VB, McLean BA, Chen X, Oudit GY.

Clin Sci (Lond). 2015 Mar;128(5):321-3. doi: 10.1042/CS20140668.

PMID:
25394290
33.

Comparison of amplicor and GeneXpert MTB/RIF tests for diagnosis of tuberculous meningitis.

Patel VB, Connolly C, Singh R, Lenders L, Matinyenya B, Theron G, Ndung'u T, Dheda K.

J Clin Microbiol. 2014 Oct;52(10):3777-80. doi: 10.1128/JCM.01235-14. Epub 2014 Jul 23.

34.

Academic portfolio in the digital era: organizing and maintaining a portfolio using reference managers.

Bhargava P, Patel VB, Iyer RS, Moshiri M, Robinson TJ, Lall C, Heller MT.

J Digit Imaging. 2015 Feb;28(1):10-7. doi: 10.1007/s10278-014-9713-0. Review.

35.

Targeting angiotensin-converting enzyme 2 as a new therapeutic target for cardiovascular diseases.

Parajuli N, Ramprasath T, Patel VB, Wang W, Putko B, Mori J, Oudit GY.

Can J Physiol Pharmacol. 2014 Jul;92(7):558-65. doi: 10.1139/cjpp-2013-0488. Epub 2014 Apr 8. Review.

PMID:
24861775
36.

Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling.

Patel VB, Zhong JC, Fan D, Basu R, Morton JS, Parajuli N, McMurtry MS, Davidge ST, Kassiri Z, Oudit GY.

Hypertension. 2014 Jul;64(1):157-64. doi: 10.1161/HYPERTENSIONAHA.114.03388. Epub 2014 May 5.

PMID:
24799609
37.

Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease.

Wang W, Patel VB, Parajuli N, Fan D, Basu R, Wang Z, Ramprasath T, Kassiri Z, Penninger JM, Oudit GY.

J Mol Med (Berl). 2014 Aug;92(8):847-58. doi: 10.1007/s00109-014-1149-y. Epub 2014 Apr 15.

PMID:
24728465
38.

Deglutition-Induced Real-Time Directional Displacements in Head-and-Neck Cancer Patients --- Dynamic Volume Shuttle Imaging Analysis.

Shankar V, Haritha C, Patel VB, Prajapathi JD, Mathews PK, Sunith GJ, Shinde P, Chaudhari LN, Meshram M, Joseph J; et al.

Pract Radiat Oncol. 2013 Apr-Jun;3(2 Suppl 1):S6. doi: 10.1016/j.prro.2013.01.020. Epub 2013 Mar 25. No abstract available.

PMID:
24674565
39.

Loss of NOX2 (gp91phox) prevents oxidative stress and progression to advanced heart failure.

Parajuli N, Patel VB, Wang W, Basu R, Oudit GY.

Clin Sci (Lond). 2014 Sep;127(5):331-40. doi: 10.1042/CS20130787.

PMID:
24624929
40.

Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inflammation, and lipotoxicity.

Mori J, Patel VB, Ramprasath T, Alrob OA, DesAulniers J, Scholey JW, Lopaschuk GD, Oudit GY.

Am J Physiol Renal Physiol. 2014 Apr 15;306(8):F812-21. doi: 10.1152/ajprenal.00655.2013. Epub 2014 Feb 19.

41.

Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation.

Mori J, Patel VB, Abo Alrob O, Basu R, Altamimi T, Desaulniers J, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY.

Circ Heart Fail. 2014 Mar 1;7(2):327-39. doi: 10.1161/CIRCHEARTFAILURE.113.000672. Epub 2014 Jan 3.

PMID:
24389129
42.

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS.

Patel VB, Clarke N, Wang Z, Fan D, Parajuli N, Basu R, Putko B, Kassiri Z, Turner AJ, Oudit GY.

J Mol Cell Cardiol. 2014 Jan;66:167-76. doi: 10.1016/j.yjmcc.2013.11.017. Epub 2013 Dec 9.

PMID:
24332999
43.

Role of angiotensin-converting enzyme 2 (ACE2) in diabetic cardiovascular complications.

Patel VB, Parajuli N, Oudit GY.

Clin Sci (Lond). 2014 Apr;126(7):471-82. doi: 10.1042/CS20130344. Review.

PMID:
24329564
44.

Stability-indicating HPLC Method for Simultaneous Determination of Aspirin and Prasugrel.

Patel SM, Patel CN, Patel VB.

Indian J Pharm Sci. 2013 Jul;75(4):413-9. doi: 10.4103/0250-474X.119816.

45.

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study.

Patel VB, Theron G, Lenders L, Matinyena B, Connolly C, Singh R, Coovadia Y, Ndung'u T, Dheda K.

PLoS Med. 2013 Oct;10(10):e1001536. doi: 10.1371/journal.pmed.1001536. Epub 2013 Oct 22.

46.

The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's disease.

El Hindy M, Hezwani M, Corry D, Hull J, El Amraoui F, Harris M, Lee C, Forshaw T, Wilson A, Mansbridge A, Hassler M, Patel VB, Kehoe PG, Love S, Conway ME.

Antioxid Redox Signal. 2014 Jun 1;20(16):2497-513. doi: 10.1089/ars.2012.4869. Epub 2013 Dec 21.

47.

Doxorubicin mediated cardiotoxicity in rats: protective role of felodipine on cardiac indices.

Gandhi H, Patel VB, Mistry N, Patni N, Nandania J, Balaraman R.

Environ Toxicol Pharmacol. 2013 Nov;36(3):787-95. doi: 10.1016/j.etap.2013.07.007. Epub 2013 Jul 22.

PMID:
23958971
48.

Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues.

Wang W, McKinnie SM, Patel VB, Haddad G, Wang Z, Zhabyeyev P, Das SK, Basu R, McLean B, Kandalam V, Penninger JM, Kassiri Z, Vederas JC, Murray AG, Oudit GY.

J Am Heart Assoc. 2013 Jul 1;2(4):e000249. doi: 10.1161/JAHA.113.000249.

49.

Diffusely metastatic digital papillary adenocarcinoma 11 years after initial presentation treated with palliative chemotherapy and radiotherapy.

Jones JA, Patel VB, Goldsmith B, Teitelbaum U, Plastaras JP.

J Clin Oncol. 2013 Aug 1;31(22):e386-9. doi: 10.1200/JCO.2012.46.4693. Epub 2013 Jun 24. No abstract available.

PMID:
23797003

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