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Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium.

Johnston BC, Zeraatkar D, Han MA, Vernooij RWM, Valli C, El Dib R, Marshall C, Stover PJ, Fairweather-Taitt S, Wójcik G, Bhatia F, de Souza R, Brotons C, Meerpohl JJ, Patel CJ, Djulbegovic B, Alonso-Coello P, Bala MM, Guyatt GH.

Ann Intern Med. 2019 Oct 1. doi: 10.7326/M19-1621. [Epub ahead of print]


The Landscape of Genetic Content in the Gut and Oral Human Microbiome.

Tierney BT, Yang Z, Luber JM, Beaudin M, Wibowo MC, Baek C, Mehlenbacher E, Patel CJ, Kostic AD.

Cell Host Microbe. 2019 Aug 14;26(2):283-295.e8. doi: 10.1016/j.chom.2019.07.008.


Family History-Wide Association Study to Identify Clinical and Environmental Risk Factors for Common Chronic Diseases.

Rasooly D, Ioannidis JPA, Khoury MJ, Patel CJ.

Am J Epidemiol. 2019 Aug 1;188(8):1563-1568. doi: 10.1093/aje/kwz125.


Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets.

Manrai AK, Ioannidis JPA, Patel CJ.

Am J Epidemiol. 2019 May 1;188(5):846-850. doi: 10.1093/aje/kwz031.


Age-dependent co-dependency structure of biomarkers in the general population of the United States.

Le Goallec A, Patel CJ.

Aging (Albany NY). 2019 Feb 28;11(5):1404-1426. doi: 10.18632/aging.101842.


Author Correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes.

Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ.

Nat Genet. 2019 Apr;51(4):764-765. doi: 10.1038/s41588-019-0377-z.


Conducting a Reproducible Mendelian Randomization Analysis Using the R Analytic Statistical Environment.

Rasooly D, Patel CJ.

Curr Protoc Hum Genet. 2019 Apr;101(1):e82. doi: 10.1002/cphg.82. Epub 2019 Jan 15.


Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes.

Lakhani CM, Tierney BT, Manrai AK, Yang J, Visscher PM, Patel CJ.

Nat Genet. 2019 Feb;51(2):327-334. doi: 10.1038/s41588-018-0313-7. Epub 2019 Jan 14. Erratum in: Nat Genet. 2019 Apr;51(4):764-765.


Exposome-wide association study of semen quality: Systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes.

Chung MK, Buck Louis GM, Kannan K, Patel CJ.

Environ Int. 2019 Apr;125:505-514. doi: 10.1016/j.envint.2018.11.037. Epub 2018 Dec 22.


Publisher Correction: Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.

Sagers JE, Brown AS, Vasilijic S, Lewis RM, Sahin MI, Landegger LD, Perlis RH, Kohane IS, Welling DB, Patel CJ, Stankovic KM.

Sci Rep. 2018 Nov 23;8(1):17449. doi: 10.1038/s41598-018-36016-9.


Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.

Wolthers BO, Frandsen TL, Patel CJ, Abaji R, Attarbaschi A, Barzilai S, Colombini A, Escherich G, Grosjean M, Krajinovic M, Larsen E, Liang DC, Möricke A, Rasmussen KK, Samarasinghe S, Silverman LB, van der Sluis IM, Stanulla M, Tulstrup M, Yadav R, Yang W, Zapotocka E, Gupta R, Schmiegelow K; Ponte di Legno toxicity working group.

Haematologica. 2019 Mar;104(3):556-563. doi: 10.3324/haematol.2018.199356. Epub 2018 Nov 22.


Using Big Data to Determine Reference Values for Laboratory Tests-Reply.

Manrai AK, Patel CJ, Ioannidis JPA.

JAMA. 2018 Oct 9;320(14):1496. doi: 10.1001/jama.2018.10956. No abstract available.


Toward Capturing the Exposome: Exposure Biomarker Variability and Coexposure Patterns in the Shared Environment.

Chung MK, Kannan K, Louis GM, Patel CJ.

Environ Sci Technol. 2018 Aug 7;52(15):8801-8810. doi: 10.1021/acs.est.8b01467. Epub 2018 Jul 20.


Bedside Lung Ultrasound in Emergency Protocol as a Diagnostic Tool in Patients of Acute Respiratory Distress Presenting to Emergency Department.

Patel CJ, Bhatt HB, Parikh SN, Jhaveri BN, Puranik JH.

J Emerg Trauma Shock. 2018 Apr-Jun;11(2):125-129. doi: 10.4103/JETS.JETS_21_17.


Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility.

Corona E, Wang L, Ko D, Patel CJ.

PLoS One. 2018 May 25;13(5):e0196676. doi: 10.1371/journal.pone.0196676. eCollection 2018.


In the Era of Precision Medicine and Big Data, Who Is Normal?

Manrai AK, Patel CJ, Ioannidis JPA.

JAMA. 2018 May 15;319(19):1981-1982. doi: 10.1001/jama.2018.2009. No abstract available.


Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.

Sagers JE, Brown AS, Vasilijic S, Lewis RM, Sahin MI, Landegger LD, Perlis RH, Kohane IS, Welling DB, Patel CJ, Stankovic KM.

Sci Rep. 2018 Apr 3;8(1):5437. doi: 10.1038/s41598-018-23609-7. Erratum in: Sci Rep. 2018 Nov 23;8(1):17449.


Model-averaged confounder adjustment for estimating multivariate exposure effects with linear regression.

Wilson A, Zigler CM, Patel CJ, Dominici F.

Biometrics. 2018 Sep;74(3):1034-1044. doi: 10.1111/biom.12860. Epub 2018 Mar 22.


Systematic identification of correlates of HIV infection: an X-wide association study.

Patel CJ, Bhattacharya J, Ioannidis JPA, Bendavid E.

AIDS. 2018 Apr 24;32(7):933-943. doi: 10.1097/QAD.0000000000001767.


Reasons for Abortion: Religion, Religiosity/Spirituality and Attitudes of Male Secondary School Youth in South Africa.

Selebalo-Bereng L, Patel CJ.

J Relig Health. 2018 Jan 17. doi: 10.1007/s10943-017-0547-1. [Epub ahead of print]


Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes.

Tangirala S, Patel CJ.

Sci Rep. 2018 Jan 8;8(1):17. doi: 10.1038/s41598-017-18585-3.


Rcupcake: an R package for querying and analyzing biomedical data through the BD2K PIC-SURE RESTful API.

Gutiérrez-Sacristán A, Guedj R, Korodi G, Stedman J, Furlong LI, Patel CJ, Kohane IS, Avillach P.

Bioinformatics. 2018 Apr 15;34(8):1431-1432. doi: 10.1093/bioinformatics/btx788.


Aether: leveraging linear programming for optimal cloud computing in genomics.

Luber JM, Tierney BT, Cofer EM, Patel CJ, Kostic AD.

Bioinformatics. 2018 May 1;34(9):1565-1567. doi: 10.1093/bioinformatics/btx787.


Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections.

Johnson CH, Athersuch TJ, Collman GW, Dhungana S, Grant DF, Jones DP, Patel CJ, Vasiliou V.

Hum Genomics. 2017 Dec 8;11(1):32. doi: 10.1186/s40246-017-0128-0.


Covariate selection for association screening in multiphenotype genetic studies.

Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N.

Nat Genet. 2017 Dec;49(12):1789-1795. doi: 10.1038/ng.3975. Epub 2017 Oct 16.


Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases.

McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS.

Am J Epidemiol. 2017 Oct 1;186(7):753-761. doi: 10.1093/aje/kwx227.


Update on the State of the Science for Analytical Methods for Gene-Environment Interactions.

Gauderman WJ, Mukherjee B, Aschard H, Hsu L, Lewinger JP, Patel CJ, Witte JS, Amos C, Tai CG, Conti D, Torgerson DG, Lee S, Chatterjee N.

Am J Epidemiol. 2017 Oct 1;186(7):762-770. doi: 10.1093/aje/kwx228.


Leveraging Population-Based Clinical Quantitative Phenotyping for Drug Repositioning.

Brown AS, Rasooly D, Patel CJ.

CPT Pharmacometrics Syst Pharmacol. 2018 Feb;7(2):124-129. doi: 10.1002/psp4.12258. Epub 2018 Jan 24.


Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives.

Magni P, Bier DM, Pecorelli S, Agostoni C, Astrup A, Brighenti F, Cook R, Folco E, Fontana L, Gibson RA, Guerra R, Guyatt GH, Ioannidis JP, Jackson AS, Klurfeld DM, Makrides M, Mathioudakis B, Monaco A, Patel CJ, Racagni G, Schünemann HJ, Shamir R, Zmora N, Peracino A.

Adv Nutr. 2017 Jul 14;8(4):532-545. doi: 10.3945/an.116.014738. Print 2017 Jul.


Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies.

Patel CJ, Kerr J, Thomas DC, Mukherjee B, Ritz B, Chatterjee N, Jankowska M, Madan J, Karagas MR, McAllister KA, Mechanic LE, Fallin MD, Ladd-Acosta C, Blair IA, Teitelbaum SL, Amos CI.

Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1370-1380. doi: 10.1158/1055-9965.EPI-17-0459. Epub 2017 Jul 14. Review.


A standard database for drug repositioning.

Brown AS, Patel CJ.

Sci Data. 2017 Mar 14;4:170029. doi: 10.1038/sdata.2017.29.


Analytic Complexity and Challenges in Identifying Mixtures of Exposures Associated with Phenotypes in the Exposome Era.

Patel CJ.

Curr Epidemiol Rep. 2017;4(1):22-30. doi: 10.1007/s40471-017-0100-5. Epub 2017 Jan 18. Review.


The Exposome Research Paradigm: an Opportunity to Understand the Environmental Basis for Human Health and Disease.

Buck Louis GM, Smarr MM, Patel CJ.

Curr Environ Health Rep. 2017 Mar;4(1):89-98. doi: 10.1007/s40572-017-0126-3. Review.


Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health.

Manrai AK, Cui Y, Bushel PR, Hall M, Karakitsios S, Mattingly CJ, Ritchie M, Schmitt C, Sarigiannis DA, Thomas DC, Wishart D, Balshaw DM, Patel CJ.

Annu Rev Public Health. 2017 Mar 20;38:279-294. doi: 10.1146/annurev-publhealth-082516-012737. Epub 2016 Dec 23. Review.



Manrai AK, Patel CJ, Gehlenborg N, Tatonetti NP, Ioannidis JP, Kohane IS.

Pac Symp Biocomput. 2016;21:180-182. No abstract available.



Karczewski KJ, Tatonetti NP, Manrai AK, Patel CJ, Titus Brown C, Ioannidis JPA.

Pac Symp Biocomput. 2017;22:117-119. doi: 10.1142/9789813207813_0012.


A review of validation strategies for computational drug repositioning.

Brown AS, Patel CJ.

Brief Bioinform. 2018 Jan 1;19(1):174-177. doi: 10.1093/bib/bbw110. Review.


Comment: Addressing the Need for Portability in Big Data Model Building and Calibration.

Patel CJ, Dominici F.

J Am Stat Assoc. 2016;111(513):127-129. Epub 2016 May 5. No abstract available.


The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.

Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS.

Environ Health Perspect. 2016 Nov;124(11):1671-1682. Epub 2016 Apr 19. Review.


A data-driven search for semen-related phenotypes in conception delay.

Patel CJ, Sundaram R, Buck Louis GM.

Andrology. 2017 Jan;5(1):95-102. doi: 10.1111/andr.12288. Epub 2016 Oct 28.


A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey.

Patel CJ, Pho N, McDuffie M, Easton-Marks J, Kothari C, Kohane IS, Avillach P.

Sci Data. 2016 Oct 25;3:160096. doi: 10.1038/sdata.2016.96.


MeSHDD: Literature-based drug-drug similarity for drug repositioning.

Brown AS, Patel CJ.

J Am Med Inform Assoc. 2017 May 1;24(3):614-618. doi: 10.1093/jamia/ocw142.


Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999-2012).

McGinnis DP, Brownstein JS, Patel CJ.

Sci Rep. 2016 Jul 26;6:30373. doi: 10.1038/srep30373.


Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.

Gao C, Patel CJ, Michailidou K, Peters U, Gong J, Schildkraut J, Schumacher FR, Zheng W, Boffetta P, Stucker I, Willett W, Gruber S, Easton DF, Hunter DJ, Sellers TA, Haiman C, Henderson BE, Hung RJ, Amos C, Pierce BL, Lindström S, Kraft P; the Colorectal Transdisciplinary Study (CORECT); Discovery, Biology and Risk of Inherited Variants in Breast Cancer (DRIVE); Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE); Follow-up of Ovarian Cancer Genetic Association and Interaction Studies (FOCI); and Transdisciplinary Research in Cancer of the Lung (TRICL).

Int J Epidemiol. 2016 Jun;45(3):896-908. doi: 10.1093/ije/dyw129. Epub 2016 Jul 17.


Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, Dudley JT.

Bioinformatics. 2016 Jun 15;32(12):i101-i110. doi: 10.1093/bioinformatics/btw282.


Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length.

Patel CJ, Manrai AK, Corona E, Kohane IS.

Int J Epidemiol. 2017 Feb 1;46(1):44-56. doi: 10.1093/ije/dyw043.


ksRepo: a generalized platform for computational drug repositioning.

Brown AS, Kong SW, Kohane IS, Patel CJ.

BMC Bioinformatics. 2016 Feb 9;17:78. doi: 10.1186/s12859-016-0931-y.



Manrai AK, Wang BL, Patel CJ, Kohane IS.

Pac Symp Biocomput. 2016;21:231-42.

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